초록 ▼

Methods for peroxide vapor sterilization of medical devices and similar instruments having long narrow lumens or diffusion restricted areas includes the step of contacting the article to be sterilized or a diffusion-restricted environment containing said article with a source of peroxide prior to ex

Methods for peroxide vapor sterilization of medical devices and similar instruments having long narrow lumens or diffusion restricted areas includes the step of contacting the article to be sterilized or a diffusion-restricted environment containing said article with a source of peroxide prior to exposure to a vacuum or a vacuum followed by plasma. The methods are such that, upon vaporization of the source of peroxide caused by the vacuum, the peroxide remains in contact with the article for a time sufficient to achieve sterilization.

대표청구항 ▼

[ What is claimed is:] [1.] A method for sterilizing an article within a container in a vacuum chamber, said method comprising:(a) placing said article in said container, wherein said container is in fluid communication with the chamber through an exit tube having a length to internal diameter ratio

[ What is claimed is:] [1.] A method for sterilizing an article within a container in a vacuum chamber, said method comprising:(a) placing said article in said container, wherein said container is in fluid communication with the chamber through an exit tube having a length to internal diameter ratio greater than or equal to 1.1;(b) contacting the interior of the container with a source of peroxide which releases hydrogen peroxide vapor, said placing and contacting steps being performed in either order;(c) reducing the pressure of the chamber and container below the vapor pressure of hydrogen peroxide;(d) generating hydrogen peroxide vapor in the container;(e) diffusing said hydrogen peroxide vapor from the container through the exit tube into said vacuum chamber; and(f) exposing said article to said hydrogen peroxide vapor for a time period sufficient to effect sterilization of said article.