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Polymer formulation for prevention of surgical adhesions 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/08
  • A61K-047/34
  • A61K-047/22
출원번호 US-0877391 (1997-06-17)
발명자 / 주소
  • Southard Jeffrey L.
  • Dunn Richard L.
출원인 / 주소
  • Atrix Laboratories, Inc.
대리인 / 주소
    Merchant & Gould P.C.
인용정보 피인용 횟수 : 34  인용 특허 : 28

초록

The invention is directed to a polymer formulation in which a pharmaceutically acceptable, biocompatible, biodegradable and/or bioerodible, water-coagulable thermoplastic polymer or copolymer which is substantially insoluble in an aqueous medium is dissolved in .epsilon.-caprolactone, a pharmaceutic

대표청구항

[ What is claimed is:] [1.] A polymer formulation suitable for use in preventing adhesions comprising:(a) .epsilon.-caprolactone;(b) a pharmaceutically acceptable biodegradable thermoplastic polymer that is substantially insoluble in an aqueous or body fluid and soluble in .epsilon.-caprolactone; an

이 특허에 인용된 특허 (28)

  1. Polson Alan M. (Fort Collins CO) Swanbom Deryl D. (Fort Collins CO) Dunn Richard L. (Fort Collins CO) Cox Charles P. (Fort Collins CO) Norton Richard L. (Fort Collins CO) Lowe Bryan K. (Fort Collins , Apparatus for forming a biodegradable implant precursor.
  2. Tipton Arthur J. (Birmingham AL) Fujita Shawn M. (Amsterdam NLX) Dunn Richard L. (Fort Collins CO), Biodegradable film dressing and method for its formation.
  3. Polson Alan M. (Fort Collins CO) Swanbom Deryl D. (Fort Collins CO) Dunn Richard L. (Fort Collins CO) Cox Charles P. (Fort Collins CO) Norton Richard L. (Fort Collins CO) Lowe Bryan K. (Fort Collins , Biodegradable implant precursor.
  4. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods for producing the same.
  5. Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.
  6. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
  7. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David P. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
  8. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.
  9. Norton Richard L. (Fort Collins CO) Knight Stephen Michael Gregory (Fort Collins CO) Tipton Arthur J. (Birmingham AL), Biodegradable polymeric composition.
  10. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable system for regenerating the periodontium.
  11. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable system for regenerating the periodontium.
  12. Messier Kenneth A. (Jewett City CT) Rhum Joseph D. (Old Lyme CT), Caprolactone polymers for suture coating.
  13. Ludwig Nelson H. (Greenfield IN) Ose Earl E. (Greenfield IN), Controlled release formulations and method of treatment.
  14. Dell, John D., Film-forming composition containing an antimicrobial agent and methods.
  15. Oh Young S. (Fairfield OH) Juneja Prem S. (Cincinnati OH) Connor Daniel S. (Cincinnati OH), Gel stick antiperspirant compositions.
  16. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Harkrader Ronald J. (Louisville CO) Rogers Jack A. (Fort Collins CO), Intragingival delivery systems for treatment of periodontal disease.
  17. St. John Kenneth (Tracy CA), Medical putty for tissue augmentation.
  18. Gregory John B. (Wayland MA), Method of treating burns using a poly-e 상세보기
  • Dunn Richard L. (Fort Collins CO) Godowski Kenneth C. (Fort Collins CO) Harkrader Ronald J. (Louisville CO) Southard George L. (Fort Collins CO), Muscosal delivery systems for treatment of periodontal disease.
  • Lundberg, Robert D., Polycaprolactone polymers.
  • Fox ; Jr. Charles L. (Ft. Lauderdale FL) Keith Alec D. (State College PA) Snipes Wallace (Pine Grove Mills PA), Polymeric diffusion burn matrix and method of use.
  • DeLuca Patrick P. (Lexington KY) Kanke Motoko (Fukuyama JPX) Sato Toyomi (Tokyo CA JPX) Schroeder Hans G. (Encinitas CA), Porous microspheres for drug delivery and methods for making same.
  • Sudmann Einar (Os CA NOX) Bonsen Pieter (Los Altos CA) Lee Eun S. (Redwood City CA), Post-surgical applications for bioerodible polymers.
  • Keith Alec D. (Miami FL) Snipes Wallace (State College PA), Protective skin matrix.
  • Harkrader Ronald J. (Louisville CO) Jones Richard R. (Fort Collins CO), Purification of benzophenanthridine alkaloids extracts from alkaloid extracts.
  • Stockel Richard F. (475 Rolling Hills Rd. Bridgewater NJ 08807), Spray on wound dressing compositions.
  • Shalaby Shalaby W. (Lebanon NJ) Jamiolkowski Dennis D. (Long Valley NJ), Surgical articles of copolymers of glycolide and e 상세보기
  • Pitt Colin G. (RTI ; P. O. Box 12194 Research Triangle Park NC 27709) Schindler Anton E. (RTI ; P. O. Box 12194 Research Triangle Park NC 27709), Sustained subdermal delivery ofdrugs using poly(e 상세보기
  • 이 특허를 인용한 특허 (34)

    1. Maspero, Fabrizio Alessandro; Ruffieux, Kurt, Biocompatible bone implant compositions and methods for repairing a bone defect.
    2. Langrana, Noshir; Verma, Devendra; Previtera, Michelle, Biomaterial and methods of use thereof for the prevention of post-operative adhesions.
    3. Molz, Fred; Felton, Sharonda, Coatings on medical implants to guide soft tissue healing.
    4. Lee-Sepsick, Kathy; Azevedo, Max S., Contrast agent generation and injection system for sonographic imaging.
    5. Lee-Sepsick, Kathy; Azevedo, Max S., Contrast agent injection system for sonographic imaging.
    6. Dunn, Richard L., Low viscosity liquid polymeric delivery system.
    7. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Method and devices for conduit occlusion.
    8. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S., Methods and devices for conduit occlusion.
    9. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S., Methods and devices for conduit occlusion.
    10. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S., Methods and devices for conduit occlusion.
    11. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S., Methods and devices for conduit occlusion.
    12. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
    13. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
    14. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
    15. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
    16. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
    17. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
    18. Lee-Sepsick, Kathy; Paxton, Lani L. L.; Marcus, Jeffrey A.; Williams, Stephen N., Methods and devices for conduit occlusion.
    19. Lee-Sepsick, Kathy, Methods and devices for delivering to conduit.
    20. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S.; Marcus, Jeffrey A., Methods and devices for delivery of compositions to conduits.
    21. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S.; Marcus, Jeffrey A., Methods and devices for delivery of compositions to conduits.
    22. Lee-Sepsick, Kathy; Azevedo, Max S.; Currie, Daniel S.; Marcus, Jeffrey A., Methods and devices for delivery of compositions to conduits.
    23. Lee-Sepsick, Kathy; Azevedo, Max S., Methods and devices for sonographic imaging.
    24. Lee-Sepsick, Kathy; Azevedo, Max S., Methods and devices for sonographic imaging.
    25. Sawhney, Amarpreet S., Methods for forming regional tissue adherent barriers and drug delivery systems.
    26. Sawhney,Amarpreet S., Methods for forming regional tissue adherent barriers and drug delivery systems.
    27. Palasis, Maria; Gordon, Lucas S., Methods of sealing an injection site.
    28. Branham,Keith; Chaubal,Mahesh V.; English,James P.; Hall,Donna; Zhao,Zhong, Phosphorous-containing compounds with polymeric chains, and methods of making and using the same.
    29. Branham, Keith; Chaubal, Mahesh V.; English, James P.; Hall, Donna; Zhao, Zhong, Phosphorus-containing compounds with polymeric chains, and methods of making and using the same.
    30. Branham, Keith; Chaubal, Mahesh V.; English, James P.; Hall, Donna; Zhao, Zhong, Phosphorus-containing compounds with polymeric chains, and methods of making and using the same.
    31. Maspero, Fabrizio Alessandro; Ruffieux, Kurt, Porous biocompatible implant material and method for its fabrication.
    32. Trieu, Hai H.; Molz, Fred, Surface treatments for promoting selective tissue attachment to medical impants.
    33. Niazi Sarfaraz K., Use of fluorocarbons for the prevention of surgical adhesions.
    34. Asgharian, Bahram; Chowhan, Masood A.; Wax, Martin B., Water insoluble polymer matrix for drug delivery.

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