$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

In vivo gene transfer methods for wound healing 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-048/00
출원번호 US-0631334 (1996-04-12)
발명자 / 주소
  • Goldstein Steven A.
  • Bonadio Jeffrey
출원인 / 주소
  • The Regent of the University of Michigan
대리인 / 주소
    Pennie & Edmonds LLP
인용정보 피인용 횟수 : 64  인용 특허 : 164

초록

The present invention relates to an in vivo method for specific targeting and transfer of DNA into mammalian repair cells. The transferred DNA may include any DNA encoding a therapeutic protein of interest. The invention is based on the discovery that mammalian repair cells proliferate and migrate i

대표청구항

[ What is claimed is:] [1.] A method for transferring a DNA molecule that directs the expression of a gene product into a mammalian repair cell, comprising applying a biocompatible matrix containing the DNA molecule to a wound in a mammalian subject, so that repair cells at the wound site acquire th

이 특허에 인용된 특허 (164)

  1. Tunc, Deger C., Absorbable bone fixation device.
  2. Okuzumi Yuzi (Belle Mead NJ) Mellon A. Darline (Bridgewater NJ) Wasserman David (Springfield NJ), Addition copolymers of lactide and glycolide and method of preparation.
  3. Brekke John H. (Duluth MN), Apparatus for biodegradable, osteogenic, bone graft substitute device.
  4. Delcommune Luc (Monfalcone ITX) Ghyselinck Philippe (Braine-L\Alleud BEX), Article made of lactic acid polymer capable of being employed particularly as a biodegradable prosthesis and process for.
  5. Kulkarni R. K. (4207 Briggs Chaney Rd. Beltsville MD 20705), Assimilable hydrophilic prosthesis.
  6. Sawyer Philip N. (7600 Ridge Blvd. Brooklyn NY 11209), Bandage with hemostatic agent and methods for preparing and employing the same.
  7. Calhoun Jason H. (Galveston TX) Mader Jon T. (Galveston TX), Biodegradable antibiotic implants and methods of their use in treating and preventing infections.
  8. Daniels Alma U. (Salt Lake City UT) Heller Jorge (Woodside CA), Biodegradable composites for internal medical use.
  9. Tuan Rocky S. (Chester Springs PA) Lin Sheldon S. (Philadelphia PA), Biodegradable drug delivery system for the prevention and treatment of osteomyelitis.
  10. Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.
  11. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
  12. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David P. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
  13. Silver Frederick A. (Long Valley NJ) Berg Richard A. (Lambertville NJ) Birk David E. (Somerset NJ) Weadock Kevin (Piscataway NJ) Whyne Conrad (Somerset NJ), Biodegradable matrix and methods for producing same.
  14. Urist Marshall R. (Pacific Palisades CA), Biodegradable organic polymer delivery system for bone morphogenetic protein.
  15. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.
  16. Urist Marshall R. (Pacific Palisade CA), Biodegradable porous ceramic delivery system for bone morphogenetic protein.
  17. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable system for regenerating the periodontium.
  18. Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Biologically inert, biocompatible-polymer conjugates.
  19. Kaplan, Donald S.; Hermes, Matthew; Muth, Ross R.; Kennedy, John, Blends of glycolide and/or lactide polymers and caprolactone and/or trimethylene carbonate polymers and absorbable surgical devices made therefrom.
  20. Kuberasampath Thangavel (Medway MA) Ridge Richard J. (Acton MA), Bone collagen matrix for implants.
  21. Kuberasampath Thangavel (Medway MA) Ridge Richard J. (Acton MA), Bone collagen matrix for xenogenic implants.
  22. Kuberasampath Thangavel (Medway MA) Ridge Richard J. (Acton MA), Bone collagen matrix for zenogenic implants.
  23. Adams Steven W. (Sunnyvale CA) Armstrong Rosa (Palo Alto CA) Rosen David (San Jose CA), Bone growth factors and inhibitors of bone resorption for promoting bone formation.
  24. Bao Qi-Bin (Livingston NJ) Dumbleton John H. (Ringwood NJ) Higham Paul A. (Ringwood NJ), Bone growth stimulator.
  25. Lynch Kenneth L. (Brookfield WI), Bone induction method.
  26. Urist Marshall R. (Pacific Palisades CA), Bone morphogenetic agents.
  27. Urist Marshall R. (Pacific Palisades CA), Bone morphogenetic protein.
  28. Urist Marshall R. (Pacific Palisades CA), Bone morphogenetic protein composition.
  29. Urist Marshall R. (Pacific Palisades CA), Bone morphogenetic protein composition.
  30. Urist Marshall R. (Pacific Palisades CA), Bone morphogenetic protein composition.
  31. Felgner, Philip L.; Kumar, Raj; Basava, Channa; Border, Richard C.; Hwang-Felgner, Jiin-Yu, Cationic lipids for intracellular delivery of biologically active molecules.
  32. Berg Richard A. (Lambertville NJ) Silver Frederick H. (Bangor PA) Pachence James M. (Lawrenceville NJ), Collagen matrix beads for soft tissue repair.
  33. Silver Fred (Bangor PA) Sharma Vinay (Long Valley NJ) Berndt Dieter R. (Allenwood NJ) Marn Louis E. (Morris Plains NJ), Collagen-based wound dressing and method for applying same.
  34. Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239) Gutmann James L. (10112 Daventry Dr. Cockeysville MD 21030) Heatfield Barry M. (33 Penny La. Baltimore MD 21209), Collagen-enzyme conjugates that exhibit no inflammatory response and method for making the same.
  35. Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Collagen-polymer conjugates.
  36. Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Collagen-polymer conjugates.
  37. Rhee Woonza (Palo Alto CA) McCullough Kimberly (Hayward CA), Collagen-polymer tubes for use in vascular surgery.
  38. Nuwayser Elie S. (Wellesley MA) Nucefora William A. (Bedford MA), Composite core coated microparticles and process of preparing same.
  39. Hutchinson Francis G. (Lymm GBX), Continuous release pharmaceutical compositions.
  40. Hutchinson Francis G. (Lymm GBX), Continuous release pharmaceutical compositions formed by freeze drying acetic acid solutions of polylactide.
  41. Nuwayser Elie S. (Wellesley MA) Nucefora William A. (Bedford MA), Controlled release composite core coated microparticles.
  42. Sparks Randall T. (Gainesville GA) Geoghegan Edward J. (Athlone IEX), Controlled release powder and process for its preparation.
  43. Cioca Gheorghe (Coatesville PA), Cosmetic and pharmaceutical sheet material containing polypeptides.
  44. Cioca Gheorghe (Coatesville PA), Cosmetic and pharmaceutical sheet material containing polypeptides.
  45. Wang Elizabeth A. (Carlisle MA) Wozney John M. (Hudson MA) Rosen Vicki (Brookline MA), DNA sequences encoding.
  46. Wozney John M. (Hudson MA) Rosen Vicki A. (Brookline MA) Wang Elizabeth A. (Carlisle MA), DNA sequences encoding 5 proteins.
  47. Wang Elizabeth A. (Carlisle MA) Wozney John M. (Hudson MA) Rosen Vicki (Brookline MA), DNA sequences encoding BMP-1 products.
  48. Wozney John M. (Hudson MA) Wang Elizabeth A. (Carlisle MA) Rosen Vicki A. (Brookline MA) Celeste Anthony J. (Hudson MA), DNA sequences encoding BMP-6 proteins.
  49. Rosen, Vicki A.; Wang, Elizabeth A.; Wozney, John M., DNA sequences encoding BMP-7 proteins.
  50. Wang Elizabeth A. (Carlisle MA) Wozney John M. (Hudson MA) Rosen Vicki (Brookline MA), DNA sequences encoding osteoinductive products.
  51. Wang Elizabeth A. (Carlisle MA) Wozney John M. (Hudson MA) Rosen Vicki A. (Brookline MA), DNA sequences encoding the osteoinductive proteins.
  52. Seeburg Peter H. (San Francisco CA), DNA vectors encoding a novel human growth hormone-variant protein.
  53. Jarrett Peter K. (Southbury CT) Casey Donald J. (Mars PA) Peake Steven L. (Ridgefield CT), Deformable, absorbable surgical device.
  54. Rhee Woonza (Palo Alto CA) Fries Louis (Los Altos CA) Damani Ramesh (Mountain View CA) McCullough Kimberly (Hayward CA) DeLustro Frank (Belmont CA), Dehydrated collagen-polymer strings.
  55. McGinity James W. (Austin TX) Ashley Susan L. (Overland Park KS), Delivery of therapeutic agents.
  56. Li Shu-Tung (1 Kiowa Ter. Oakland NJ 07436), Dense collagen membrane matrices for medical uses.
  57. Muchow David C. (Transit Township ; Sibley County MN) Sirvio Larry M. (Cottage Grove MN), Device and method for extended delivery of pharmacologically active agents to the ear.
  58. Pawelchak, John M.; Freeman, Frank M., Dressings, granules, and their use in treating wounds.
  59. Hoffman ; Jr. Harmon (Wyckoff NJ) Schankereli Kemal (Stillwater MN) Chvapil Milos (Tucson AZ), Drug delivery collagen-impregnated synthetic vascular graft.
  60. Kaufman Herbert E. (300 Lake Marina Dr. ; Unit 18E New Orleans LA 70124), Drug delivery system.
  61. Kaufman Herbert E. (300 Lake Marina Dr. ; Unit 18E New Orleans LA 70124), Drug delivery system.
  62. Sahatjian Ronald (Lexington MA), Drug delivery system making use of a hydrogel polymer coating.
  63. Balazs Endre A. (Ft. Lee NJ) Leshchiner Adolf (Fairview NJ) Larsen Nancy E. (Ridgefield Park NJ), Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same.
  64. Woo Savio L. C. (5343 Rutherglenn Houston TX 77096) Nordloh Peter W. (1104 S. 8th St. Burlington IA 52601) Stenlund Arne (1 Bungtown Rd. Cold Spring Harbor NY 11724), Episomal vector systems and related methods.
  65. Sindrey Dennis R. (Etobicoke CAX), Essentially pure human parathyroid hormone.
  66. Reich Cary (Laguna Hills CA), Fibronectin wound-healing dressings.
  67. Badylak Stephen F. (2610 Nottingham Pla. West Lafayette IN 47906) Demeter Robert J. (360 Cottonwood Dr. Mooresville IN 46158) Hiles Michael (3817 Cologne Ct. Indianapolis IN 46208) Voytik Sherry (271, Fluidized intestinal submucosa and its use as an injectable tissue graft.
  68. Huc Alain (Ste Foy-les-Lyons FRX) Gimeno Rene (Pelussin FRX) Herbage Daniel (Lyons FRX), Forms of microencapsulation of medicinal substances by homogeneous layers of native collagen.
  69. Ron Eyal (Lexington MA) Schaub Robert G. (Pelham NH) Turek Thomas J. (Boston MA), Formulations of blood clot-polymer matrix for delivery of osteogenic proteins.
  70. Erwin Robert L. (San Francisco CA), Glucan/collagen therapeutic eye shields.
  71. Badylak Stephen F. (W. Lafayette IN) Geddes Leslie A. (W. Lafayette IN) Shelbourne K. Donald (Indianapolis IN) Lantz Gary C. (Lafayette IN) Coffey Arthur C. (Indianapolis IN), Graft for promoting autogenous tissue growth.
  72. Badylak Stephen F. (W. Lafayette IN) Geddes Leslie A. (W. Lafayette IN) Shelbourne K. Donald (Indianapolis IN) Lantz Gary C. (Lafayette IN) Coffey Arthur C. (Indianapolis IN), Graft for promoting autogenous tissue growth.
  73. Lewis Danny H. (Hartselle AL), Growth promoters for animals.
  74. Magnusson Ingvar (High Springs FL) Batich Christopher (Gainesville FL), Guided periodontal tissue regeneration.
  75. Nathan Ranga (Newark CA) Seyedin Saied (Mountain View CA) Piez Karl (Menlo Park CA) Bentz Hanne (Palo Alto CA), Inductive collagen based bone repair preparations.
  76. Nathan Ranga (Newark) Seyedin Saeid (Mountain View) Piez Karl (Menlo Park) Bentz Hanne (Palo Alto CA), Inductive collagen-based bone repair preparations.
  77. Lemons J. E. (c/o University of Alabama in Birmingham ; School of Dentistry ; Box 49 Birmingham AL 35294), Inorganic and organic composition for treatment of bone lesions.
  78. Joffe Edward J. (940 Park Ave. Linden NJ 07036), Interconnecting panels for knockdown structures.
  79. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Harkrader Ronald J. (Louisville CO) Rogers Jack A. (Fort Collins CO), Intragingival delivery systems for treatment of periodontal disease.
  80. Berg Eric P. (Plymouth MN) Tuch Ronald J. (Plymouth MN) Dror Michael (Edina MN) Wolff Rodney G. (Minnetonka Beach MN), Intravascular stent and method.
  81. Trml Pertti (Reikonkatu 7 C 7 SF-33730 Tampere FIX) Vainionp Seppo (Orapihlajatie 21-27 B 12 SF-00320 Helsinki FIX) Rokkanen Pentti (Marjaniemenranta 29 SF-00930 Helsinki FIX) Helevirta Pertti (Ojava, Layered surgical biocomposite material.
  82. Hostetler Karl Y. (Del Mar CA) Kumar Raj (San Diego CA) Stuhmiller Louise M. (Rancho Santa Fe CA), Liponucleotide-containing liposomes.
  83. Nozawa Takamitsu (Tokyo JPX) Kishi Takao (Funabashi JPX) Iizuka Shigeo (Tokyo JPX), Liquid spraying device.
  84. Tice Thomas R. (Birmingham AL) Meyers William E. (Helena AL), Living cells encapsulated in crosslinked protein.
  85. Rosenberg Robert D. (Jamestown RI) Simons Michael (Chestnut Hill MA) Edelman Elazer (Brookline MA) Langer Robert S. (Newton MA) DeKeyser Jean-Luc (Brussels BEX), Localized oligonucleotide therapy.
  86. Hammonds ; Jr. R. Glenn (Berkeley CA) Mason Anthony J. (Burlingame CA), Mammalian expression of the bone morphogenetic protein-2B using BMP2A/BMP2B fusion.
  87. Leonard Robert J. (Lynnfield MA) Harman S. Mitchell (Ellicott City MD), Manufacture of partially fused peptide pellet.
  88. Tang Reginald T. (Warren NJ) Mares Frank (Whippany NJ) Boyle ; Jr. William J. (Parsippany NJ) Chiu Tin-Ho (Millburn NJ) Patel Kundanbhai M. (Landing NJ), Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lact.
  89. Wahlig Helmut (Darmstadt DEX) Dingeldain Elvira (Dreieich DEX) Braun Dietrich (Darmstadt-Arheilgen DEX), Medicinally useful, shaped mass of collagen resorbable in the body.
  90. Peyman Gholam A. (123 Walnut St. New Orleans LA 70118), Method and apparatus for controlled release drug delivery to the cornea and anterior chamber of the eye.
  91. Brekke John H. (Duluth MN), Method and apparatus for diodegradable, osteogenic, bone graft substitute device.
  92. Davis William M. (Tucson AZ) Chvapil Milos (Tucson AZ), Method and apparatus for treatment of fibrotic lesions.
  93. March Keith L. (Carmel IN) Hathaway David R. (Indianapolis IN) Wilensky Robert L. (Indianapolis IN), Method for delivery of smooth muscle cell inhibitors.
  94. Schwarz Martin A. ; Sullivan Lee M. ; Bober Loretta A. ; Grace Michael J., Method for enhancing wound healing/repair with IL-4.
  95. Hermes Matthew E. (Easton CT) Muth Ross R. (Brookfield CT), Method for improving the storage stability of a polymeric article susceptible to hydrolytic degradation and resulting ar.
  96. Ogawa Yasushi (Pacifica CA) Schmidt David K. (Santa Cruz CA) Armstrong Rosa (Palo Alto CA) Nathan Ranga (Newark CA) Thompson Andrea Y. (Mountain View CA) Seyedin Saeid M. (Saratoga CA), Method for inducing bone growth.
  97. Mathiowitz Edith (Brookline MA) Bernstein Howard (Cambridge MA) Morrel Eric (Needham MA) Schwaller Kirsten (Duxbury MA), Method for producing protein microspheres.
  98. Eppley Barry L. (7702C Chaterly Ct. Indianapolis IN 46214) Krukowski Marilyn D. (24 Washington Terrace St. Louis MO 63112) Osdoby Philip A. (134 Holly Garden Dr. Ballwin MO 63021), Method for promoting hard tissue growth and repair in mammals.
  99. Tice Thomas R. (Birmingham AL) Dillon Deborah L. (Helena AL) Mason David W. (Birmingham AL) McRae-McFarlane Amanda (Vastra Frolunda SEX) Dahlstrom Annica B. (Askin SEX), Method for stimulating nerve fiber growth.
  100. Brizzolara Nancy S. (Congers NY) Lanzilotti Michael G. (Pearl River NY) Lawter James R. (Goshen NY), Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket,.
  101. Neer Robert M. (Cambridge MA) Potts ; Jr. John T. (Newton MA) Slovik David M. (Newton MA), Method of increasing bone mass.
  102. Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239), Method of inducing osseous formation by implanting bone graft material.
  103. Bentz Hanne (Palo Alto CA) Ellingsworth Larry (San Jose CA) Armstrong Rosa (Palo Alto CA), Method of treating inflammation.
  104. Hunziker Ernst B. (Riedholz CHX), Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone.
  105. Wozney John M. (Hudson MA) Wang Elizabeth A. (Carlisle MA) Rosen Vicki A. (Brookline MA), Methods for producing BMP-7 proteins.
  106. Wallace Donald G. (Menlo Park CA) Smestad Thomas L. (Palo Alto CA) McPherson John M. (Sunnyvale CA) Piez Karl A. (Menlo Park CA) Seyedin Saeid (Sunnyvale CA) Armstrong Rosa (Palo Alto CA), Methods of bone repair using collagen.
  107. Schwartz Robert J. (Houston TX) DeMayo Franco J. (Houston TX) O\Malley Bert W. (Houston TX), Myogenic vector systems.
  108. Vert Michel (Deville-les-Rouen FRX) Chabot Francois (Rouen FRX) Leray Jean (Sevres FRX) Christel Pascal (Paris FRX), New prosthesis parts, their preparation and their application.
  109. Kuberasampath Thangavel (Medway MA) Rueger David C. (West Roxbury MA), Osteogenic devices.
  110. Oppermann Hermann (Medway MA) Kuberasampath Thangavel (Medway MA) Rueger David C. (West Roxbury MA) Ozkaynak Engin (Milford MA), Osteogenic devices.
  111. Oppermann Hermann (Medway MA) Ozkaynak Engin (Milford MA) Kuberasampath Thangavel (Medway MA) Rueger David C. (Hopkinton MA) Pang Roy H. L. (Medway MA), Osteogenic devices.
  112. Oppermann Hermann (Medway MA) Ozkaynak Engin (Milford MA) Rueger David C. (Hopkinton MA) Kuberasampath Thangavel (Medway MA), Osteogenic devices.
  113. Parsons Thomas F. (Arcadia CA) Sen Arup (Van Nuys CA) Grinna Lynn (Santa Monica CA) Hersh Carol (Great Neck NY) Theofan Georgia (Los Angeles CA), Osteogenic factors.
  114. Oppermann Hermann (Medway MA) Kuberasampath Thangavel (Medway MA) Rueger David C. (West Roxbury MA) Ozkaynak Engin (Milford MA), Osteogenic proteins.
  115. Oppermann Hermann (Medway MA) Kuberasampath Thangavel (Medway MA) Rueger David C. (West Roxbury MA) Ozkaynak Engin (Milford MA), Osteogenic proteins.
  116. Oppermann Hermann (Medway MA) Ozkaynak Engin (Milford MA) Kuberasampath Thangavel (Medway MA) Rueger David C. (Hopkinton MA) Pang Roy H. L. (Medway MA), Osteogenic proteins.
  117. Kuberasampath Thangavel (Medway MA) Rueger David C. (West Roxbury MA), Osteogenic proteins and polypeptides.
  118. Wang Elizabeth A. (Carlisle MA) Wozney John M. (Hudson MA) Rosen Vicki (Boston MA), Osteoinductive factors.
  119. Ikada Yoshito (Uji JPX) Suong Hyu H. (Uji JPX) Shimizu Yoshihiko (Uji JPX) Watanabe Satoshi (Kyoto JPX) Nakamura Tatsuo (Kyoto JPX) Suzuki Masakazu (Ayabe JPX) Shimamoto Takeshi (Nagaokakyo JPX), Osteosynthetic pin.
  120. Pang Peter K. T. (University of Alberta ; Dept. of Physiology ; 7-55 Medical Science Bldg. Edmonton CAX T6G 2H7) Shan Jie (Edmonton CAX), Parathyroid hormone analogues substituted at AA 25, 26, 27, and use in osteoporosis treatment.
  121. Leonard Robert J. (Lynnfield MA) Harman S. Mitchell (Ellicott City MD), Partially fused peptide pellet.
  122. Grinnell Frederick (Dallas TX), Peptide inhibitors of wound contraction.
  123. Jernberg Gary R. (99 Navaho Ave. Suite 102 Mankato MN 56001), Periodontal barrier and method for aiding periodontal tissue regeneration.
  124. Ikada Yoshito (Uji JPX) Gen Shokyu (Kyoto JPX), Periodontium-regenerative materials.
  125. Prisell Per (Wollmar Yxkullsgatan 15A S-116 50 Stockholm SEX) Norstedt Gunnar (Foerfattavaegen 46 S-116 42 Bromma SEX), Pharmaceutical preparation.
  126. Hollinger Jeffrey O. (Glenwood MD), Polylactic-polyglycolic acids combined with an acidic phospholipid-lysozyme complex for healing osseous tissue.
  127. Mathiowitz Edith (Brookline MA) Langer Robert S. (Somerville MA) Warshawsky Abraham (Rehovot MA ILX) Edelman Elazar (Brookline MA), Polymer composite for controlled release or membrane formation.
  128. Jarrett Peter K. (Southbury CT) Casey Donald J. (Mars PA) Rosati Louis (Norwalk CT) Dwyer James W. (Brookfield CT), Polymeric surgical staple.
  129. Findlay Christopher J. (Cambridge CAX), Porous immobilization support prepared from animal bone.
  130. DeLuca Patrick P. (Lexington KY) Kanke Motoko (Fukuyama JPX) Sato Toyomi (Tokyo CA JPX) Schroeder Hans G. (Encinitas CA), Porous microspheres for drug delivery and methods for making same.
  131. Chu George (Sunnyvale CA), Preparation of collagen hydroxyapatite matrix for bone repair.
  132. Kaplan Donald S. (Weston CT) Hermes Matthew E. (Norwalk CT) Muth Ross R. (Brookfield CT) Kennedy John J. (Stratford CT), Process for making a surgical device using two-phase compositions.
  133. Fong, Jones W., Process for preparation of microspheres.
  134. Kaplan Donald S. (Weston CT) Hermes Matthew E. (Norwalk CT) Muth Ross R. (Brookfield CT) Kennedy John J. (Stratford CT), Process of making an absorbable surgical device.
  135. Fong Jones W. (Parsippany NJ), Processes for preparation of microspheres.
  136. Chu George H. (Sunnyvale CA) Ogawa Yasushi (Pacifica CA) McPherson John M. (Framingham MA) Ksander George (Redwood City CA) Pratt Bruce (Union City CA) Hendricks Diana (Brea CA) McMullin Hugh (San Br, Processes for producing collagen matrixes and methods of using same.
  137. Rueger David C. (Hopkinton MA) Kuberasampath Thangavel (Medway MA) Oppermann Hermann (Medway MA) Ozkaynak Engin (Milford MA), Prosthetic devices having enhanced osteogenic properties.
  138. Kronenberg Henry M. (Belmont MA) Nussbaum Samuel R. (Weston MA) Doi Tomoko (Osaka JPX), Recombinant DNA method for production of parathyroid hormone.
  139. Kandel Rita A. (Toronto CAX), Reconstituted cartridge tissue.
  140. Fues Johann-Friedrich (Grevenbroich DEX) Ritter Wolfgang (Haan DEX), Resorbable bone wax.
  141. Fues Johann-Friedrich (Grevenbroich DEX) Ritter Wolfgang (Haan DEX), Resorbable bone wax.
  142. Li Shu-Tung (1 Kiowa Ter. Oakland NJ 07436), Soft tissue closure systems.
  143. Ledley Fred D. ; O'Malley ; Jr. Bert W., Somatic gene therapy to cells associated with fluid spaces.
  144. Jamiolkowski Dennis D. (Long Valley NJ) Gaterud Mark T. (Annandale NJ) Newman ; Jr. Hugh D. (Chester NJ) Shalaby Shalaby W. (Lebanon NJ), Surgical fastener made from glycolide-rich polymer blends.
  145. Smith Carl R. (Bloomingdale NJ) Gaterud Mark T. (Annandale NJ) Jamiolkowski Dennis D. (Long Valley NJ) Newman ; Jr. Hugh D. (Chester NJ) Shalaby Shalaby W. (Lebanon NJ), Surgical fastener made from glycolide-rich polymer blends.
  146. Orsolini Piero (Martigny) Mauvernay Rolland-Yves (Lausanne) Deghenghi Romano (Lausanne CHX), Sustained and controlled release of water insoluble polypeptides.
  147. Fujioka Keiji (Ibaraki JPX) Sato Shigeji (Ibaraki JPX) Takada Yoshihiro (Ibaraki JPX) Sasaki Yoshio (Ibaraki JPX) Tamura Nobuhiko (Ibaraki JPX), Sustained pulsewise release pharmaceutical preparation.
  148. Stadler Joan K. (3313 Oakland St. Ames IA 50010) Antonelli Nunzio M. (via Pezze del Sole ; 24 Bari ITX 70125), Synergistic method for host cell transformation.
  149. Rosensaft Michael N. (Monsey NY) Webb Richard L. (Darien CT), Synthetic polyester surgical articles.
  150. Rosensaft Michael N. (Monsey NY) Webb Richard L. (Darien CT), Synthetic polyester surgical articles.
  151. Kossovsky Nir (Los Angeles CA) Hnatyszyn H. James (Los Angeles CA) Gelman Andrew (Los Angeles CA), Targeted transfection nanoparticles.
  152. Badylak Stephen F. (West Lafayette IN) Geddes Leslie A. (West Lafayette IN) Shelbourne K. Donald (Indianapolis IN) Lantz Gary C. (Lafayette IN) Coffey Arthur C. (Indianapolis IN), Tendon or ligament graft for promoting autogenous tissue growth.
  153. Badylak Stephen F. (West Lafayette IN) Geddes Leslie A. (West Lafayette IN) Lantz Gary (Lafayette IN) Coffey Arthur C. (Indianapolis IN), Tissue graft composition.
  154. Badylak Stephen F. (West Lafayette IN) Geddes Leslie A. (West Lafayette IN) Lantz Gary (Lafayette IN) Coffey Arthur C. (Indianapolis IN), Tissue graft composition.
  155. Badylak Steven F. (2610 Nottingham Pl. West Lafayette IN 47906) Demeter Robert J. (360 Cottonwood Dr. Mooresville IN 46158) Hiles Michael (3817 Cologne Ct. Indianapolis IN 46208) Voytik Sherry (271 S, Tissue graft for surgical reconstruction of a collagenous meniscus and method therefor.
  156. Koezuka Masahiro (Osaka JPX) Takaoka Kunio (Osaka JPX) Suzuki Kaneo (Nara JPX) Yasugi Shigeo (Nara JPX), Tissue-affinitive collagen for osteogenesis and method of producing the same.
  157. Recker Robert R. (3309 S. 116th St. Omaha NE 68144), Treatment for osteoporosis using growth hormone releasing factor (GRF) in combination with parathyroid hormone (PTH).
  158. Nabel Elizabeth G. (Ann Arbor MI) Nabel Gary J. (Ann Arbor MI), Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor.
  159. Nabel Elizabeth G. ; Nabel Gary J., Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor.
  160. Kaplan Donald S. (Weston CT) Hermes Matthew E. (Norwalk CT) Muth Ross R. (Brookfield CT) Kennedy John J. (Stratford CT), Two-phase compositions for absorbable surgical devices.
  161. Kavoussi Harold P. (2717 N. San Angelo Dr. Claremont CA 91711), Viscoelastic collagen gel for ophthalmic surgery.
  162. Shioya, Nobuyuki; Kuroyanagi, Yoshimitsu; Kounami, Yasuo; Kobayashi, Tatsuhiko, Wound covering.
  163. Bentley J. Peter (Portland OR) Fellman Jack H. (Portland OR), Wound dressing protocol utilizing collagen gelatin formed with iodine.
  164. Bentley J. Peter (Portland OR) Fellman Jack H. (Portland OR), Wound healing kit comprised of gelable collagen.

이 특허를 인용한 특허 (64)

  1. Lockwood, Jeffrey S.; Petrosenko, Robert, Access openings in vacuum bandage.
  2. Zhang,Guanghui, Bioabsorbable blends and surgical articles therefrom.
  3. Sybert, Daryl R.; Shimp, Lawrence A.; Boyce, Todd M.; Boyle, John W., Biocompatible osteogenic band for repair of spinal disorders.
  4. Sybert, Daryl R.; Shimp, Lawrence A.; Boyce, Todd M.; Boyle, John W., Biocompatible osteogenic band for repair of spinal disorders.
  5. Sybert, Daryl R.; Shimp, Lawrence A.; Boyce, Todd M.; Boyle, John W., Biocompatible osteogenic band for repair of spinal disorders.
  6. Sybert,Daryl R; Shimp,Lawrence A.; Boyce,Todd M; Boyle,John W., Biocompatible osteogenic band for repair of spinal disorders.
  7. Isaev, Artur Aleksandrovich; Kiselev, Sergej L'vovich; Deev, Roman Vadimovich; Bozo, Il'ya Yadigerovich; Filonenko, Elena Sergeevna, Biocomposite for regeneration of injured tissue and organs, a kit for making the biocomposite, a method of making the biocomposite and a method of treating injuries.
  8. Dutta,Debashis, Biodegradable drug delivery material for stent.
  9. Dutta, Debashis, Biodegradable stent of a polyorthoester polymer or a polyanhydride polymer.
  10. Cook, Russell L.; Antone, Duraid S., Bone graft materials and methods.
  11. Cook, Russell L.; Antone, Duraid S., Bone graft materials and methods.
  12. Fritz, Ulf; Fritz, Olaf; Gordy, Thomas A.; Wojcik, Ronald; Blümmel, Jacques; Küller, Alexander, Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same.
  13. Williams, Lewis T., Combination PDGF, KGF, IGF, and IGFBP for wound healing.
  14. Coffey, Arthur C., Combination SIS and vacuum bandage and method.
  15. Badylak, Stephen F.; Bonadio, Jeffrey; Voytik, Sherry, Composition and method for production of transformed cells.
  16. Badylak, Stephen F.; Bonadio, Jeffrey; Voytik, Sherry, Composition and method for production of transformed cells.
  17. Goldstein Steven ; Levy Robert J. ; Labhasetwar Vinod ; Bonadio Jeffrey F., Compositions and methods for coating medical devices.
  18. Baird, Andrew; Gonzalez, Ana Maria; Logan, Ann; Berry, Martin, Compositions and methods for delivery of agents for neuronal regeneration and survival.
  19. Upton, Zee; Van Lonkhuyzen, Derek, Fibronectin: growth factor chimeras.
  20. Banerjee,Pallab; Reichardt,Wilfried; Weissleder,Ralph; Bogdanov,Alexei, Hyperbranched dendron and methods of synthesis and use thereof.
  21. Boyce, Todd M; Shimp, Lawrence A., Implant for orthopedic applications.
  22. Fritz, Ulf; Fritz, Olaf; Gordy, Thomas A.; Wojcik, Ronald; Blümmel, Jacques; Küller, Alexander, Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same.
  23. Fritz, Ulf; Fritz, Olaf; Gordy, Thomas A.; Wojcik, Ronald; Blümmel, Jacques; Küller, Alexander, Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same.
  24. Harder, Philipp; Fritz, Olaf; Fritz, Ulf, Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same.
  25. Harder, Philipp; Fritz, Olaf; Fritz, Ulf, Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same.
  26. Hendriks, Marc, Medical devices and methods for reducing localized fibrosis.
  27. Donald A. Tomalia ; Lajos Balogh, Method and articles for transfection of genetic material.
  28. Dalal, Paresh S.; Diamaano, Godofredo R.; Kulkarni, Shailesh C., Method for producing porous β-tricalcium phosphate granules.
  29. Dalal,Paresh S; Dimaano,Godofredo R; Toth,Carol A; Kulkarni,Shailesh C, Method of delivering a bioactive agent with porous β-tricalcium phosphate granules.
  30. Luo Dan ; Saltzman W. Mark ; Han Ernest ; Belcheva Nadya, Method of enhancing the delivery of nucleic acids using silica nanoparticles.
  31. Dalal,Paresh S; Dimaano,Godofredo R; Toth,Carol A; Kulkarni,Shailesh C, Method of forming bone with porous βtricalcium phosphate granules.
  32. Beaulieu, Andre; Paquin, Robert, Method of producing concentrated non-buffered solutions of fibronectin.
  33. Meenhard Herlyn ; Mark Nesbit ; Kapaettu Satyamoorthy, Methods for inducing localized vascular development and enhancing the repair of a wound in the mammamian dermis.
  34. Herndon, David N.; Perez-Polo, Jose R.; Barrow, Robert E., Methods to enhance wound healing and enhanced wound coverage material.
  35. Murphy, William L.; Mooney, David J.; Kohn, David H.; Spalding, Gabriel C.; Dearing, Matthew T., Mineral and cellular patterning on biomaterial surfaces.
  36. Murphy, William L.; Peters, Martin C.; Mooney, David J., Mineralization and biological modification of biomaterial surfaces.
  37. Murphy, William L.; Peters, Martin C.; Mooney, David J.; Kohn, David H., Mineralization and biological modification of biomaterial surfaces.
  38. Murphy, William L.; Peters, Martin C.; Mooney, David J.; Kohn, David H., Mineralization and biological modification of biomaterial surfaces.
  39. Unger, Gretchen M., Nanoparticle encapsulation system and method.
  40. Wiederanders,Bernd; Maubach,Gunter, Nucleic acids encoding chimeric proteins comprising BMP-2 and a proteinase inhibitor.
  41. Garigapati, Venkat R.; TenHuisen, Kevor S., Organophosphorous and multivalent metal compound compositions and methods.
  42. Garigapati, Venkat R.; Hess, Brian J.; Kimsey, Cassandra L.; Murphy, Matthew E., Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods.
  43. Herlyn,Meenhard; Kalabis,Jiri, Organotypic intestinal culture and methods of use thereof.
  44. Gopal,T. Venkat, Peptide-mediated gene transfer.
  45. Dalal, Paresh S.; Dimaano, Godofredo R.; Toth, Carol Ann; Kulkarni, Shailesh C., Porous β-tricalcium phosphate granules for regeneration of bone tissue.
  46. Serhan, Hassan; Mraz, Paul; Slivka, Michael Andrew; O'Neil, Mike, Regenerative implants for stabilizing the spine and devices for attachment of said implants.
  47. Beaulieu,Andre; Paquin,Robert; Lariviere,Benoit, Solid wound healing formulations containing fibronectin.
  48. Grunze, Michael; Fritz, Ulf, Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface.
  49. Awad, Hani A.; Schwarz, Edward M., Targeted delivery of therapeutic agents with lyophilized matrices.
  50. Intini, Giuseppe; Andreana, Sebastiano; Dziak, Rosemary; Bobek, Libuse Anna, Tissue implants and methods for making and using same.
  51. Geremakis, Perry; Grasso, Jennifer; Knaack, David; Lin, Jo-Wen; Shimp, Lawrence; Waterman, Robert; Winterbottom, John, Tissue-derived mesh for orthopedic regeneration.
  52. Sosnowski, Barbara A.; Pierce, Glenn, Traversal of nucleic acid molecules through a fluid space and expression in repair cells.
  53. Lockwood, Jeffrey S.; Petrosenko, Robert, Vacuum bandage packing.
  54. Lockwood, Jeffrey S.; Petrosenko, Robert; Risk, Jr., James R., Vacuum therapy and cleansing dressing for wounds.
  55. Lockwood, Jeffrey S.; Petrosenko, Robert; Risk, Jr., James Robert, Vacuum therapy and cleansing dressing for wounds.
  56. Lockwood, Jeffrey S.; Petrosenko, Robert; Risk, Jr., James Robert, Vacuum therapy and cleansing dressing for wounds.
  57. Lockwood, Jeffrey S.; Petrosenko, Robert, Vented vacuum bandage with irrigation for wound healing and method.
  58. Petrosenko, Robert; Wilkinson, Kevin L., Wound packing for preventing wound closure.
  59. Henley, Alan Wayne; Moses, Leigh Marie; Sanderson, Ronald Leslie; Howard, John; Price, James H.; Bessette, Russell W., Wound treatment apparatus.
  60. Henley, Alan Wayne; Moses, Leigh Marie; Sanderson, Ronald Leslie; Howard, John; Price, James H.; Bessette, Russell W., Wound treatment apparatus.
  61. Risk, Jr., James R.; Petrosenko, Robert, Wound treatment apparatus.
  62. Risk, Jr., James R.; Petrosenko, Robert, Wound treatment apparatus.
  63. Risk, Jr., James R.; Petrosenko, Robert, Wound treatment apparatus having a display.
  64. Lockwood, Jeffrey S.; Petrosenko, Robert, Wound vacuum therapy dressing kit.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로