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Hybrid matrix implants and explants 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01N-063/00
  • A61K-048/00
  • A61F-013/00
  • C12N-005/00
출원번호 US-0548002 (1995-10-25)
발명자 / 주소
  • Mineau-Hanschke Rochelle
출원인 / 주소
  • Transkaryotic Therapies, Inc.
대리인 / 주소
    Fish & Richardson P.C.
인용정보 피인용 횟수 : 51  인용 특허 : 12

초록

An implantable device having a body of matrix material made up of insoluble collagen fibrils, and disposed therewithin

대표청구항 ▼

[ What is claimed is:] [1.] A composition comprising a body of matrix material comprising insoluble collagen fibrils, there being embedded within the body of matrix material(a) a plurality of cultured vertebrate cells genetically engineered to express a medically useful polyeptide; and(b) a pluralit

이 특허에 인용된 특허 (12)

  1. Li Albert Pak-Hung (St. Louis MO) Whitehead Timothy D. (St. Louis MO) Beck Dale J. (St. Louis MO) Barker George E. (St. Louis MO), Biological artificial liver.
    상세보기
  2. Kopchick John J. (Verona NJ) Leung Frederick C. (Scotch Plains NJ) Livelli Thomas J. (Lyndhurst NJ) Malavarca Richard H. (South Orange NJ), Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH.
    상세보기
  3. Weinberg Crispin B. (Brookline MA), Fibrin-collagen tissue equivalents and methods for preparation thereof.
    상세보기
  4. Bell Eugene (Dedham MA) Dubertret Louis (Paris FRX), Skin-equivalent prepared by the use of punch biopsy.
    상세보기
  5. Naughton Gail K. (Groton VT) Naughton Brian A. (Groton VT), Three-dimensional cell and tissue culture system.
    상세보기
  6. Naughton Gail K. (Groton VT) Naughton Brian A. (Groton VT), Three-dimensional cell and tissue culture system.
    상세보기
  7. Naughton Gail K. (Groton VT) Naughton Brian A. (Groton VT), Three-dimensional skin culture system.
    상세보기
  8. Bell Eugene (Dedham MA), Tissue-equivalent and method for preparation thereof.
    상세보기
  9. Dean ; Jr. Robert C. (Norwich VT) Silver Frederick H. (Long Valley NJ) Berg Richard A. (Lambertville NJ) Phillips Philip G. (Norwich VT) Runstadler ; Jr. Peter W. (Hanover NH), Weighted collagen microsponge for immobilizing bioactive material.
    상세보기
  10. Dean ; Jr. Robert C. (Norwich VT) Silver Frederick H. (Long Valley NJ) Berg Richard A. (Lambertville NJ) Phillips Philip G. (Norwich VT) Runstadler ; Jr. Peter W. (Hanover NH), Weighted collagen microsponge for immobilizing bioactive material.
    상세보기
  11. Dean ; Jr. Robert C. (Norwich VT) Silver Frederick H. (Long Valley NJ) Berg Richard A. (Lambertville NJ) Phillips Philip G. (Norwich VT) Runstadler ; Jr. Peter W. (Hanover NH) Maffia Gennaro J. (Leba, Weighted collagen microsponge for immobilizing bioactive materials.
    상세보기
  12. Dean ; Jr. Robert C. (Norwich VT) Cahn Frederick (Bellmont MA) Phillips Philip G. (Norwich VT), Weighted microsponge for immobilizing bioactive material.
    상세보기

이 특허를 인용한 특허 (51)

  1. Shults, Mark C.; Brauker, James H.; Carr-Brendel, Victoria; Tapsak, Mark A.; Markovic, Dubravka; Updike, Stuart J.; Rhodes, Rathbun K., Analyte measuring device.
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  2. Brauker, James H.; Boock, Robert; Rixman, Monica; Simpson, Peter C.; Brister, Mark; Shults, Mark, Analyte sensor.
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  3. Kamath, Apurv Ullas; Simpson, Peter C.; Brauker, James H.; Goode, Jr., Paul V., Calibration techniques for a continuous analyte sensor.
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  4. Kamath, Apurv Ullas; Simpson, Peter C.; Brauker, James H.; Goode, Jr., Paul V., Calibration techniques for a continuous analyte sensor.
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  5. Kamath, Apurv Ullas; Simpson, Peter C.; Brauker, James H.; Goode, Jr., Paul V., Calibration techniques for a continuous analyte sensor.
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  6. Blahut, Eric, Cell and tissue culture container.
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  7. Smith, R. Lane; Tarrant, Laurence J. B.; Kusanagi, Akihiko; Claesson, Hans P. I., Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof.
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  8. Petisce, James R.; Woo, Kum Ming; Ha, Victor; Nicholas, Melissa; Boock, Robert, Cellulosic-based interference domain for an analyte sensor.
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  9. Petisce, James R.; Woo, Kum Ming; Ha, Victor; Nicholas, Melissa, Cellulosic-based resistance domain for an analyte sensor.
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  10. Geistlich, Peter; Schloesser, Lothar, Collagen carrier of therapeutic genetic material and method.
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  11. Mansbridge,Jonathan N., Compositions comprising conditioned cell culture media and uses thereof.
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  12. Sonenshein, Abraham L., Compositions, methods and kits for repressing virulence in gram positive bacteria.
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  13. Carroll, F. Ivy, Compounds and methods for promoting smoking cessation.
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  14. Naughton, Gail K.; Horwitz, David L.; Applegate, Mark A.; Zeltinger, Joan; Mansbridge, Jonathan N.; Kern, Andreas; Landeen, Lee K.; Ratcliffe, Anthony; Pinney, R. Emmett, Conditioned cell culture medium compositions and methods of use.
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  15. Naughton, Gail K.; Horwitz, David L.; Applegate, Mark A.; Zeltinger, Joan; Mansbridge, Jonathan N.; Kern, Andreas; Landeen, Lee K.; Ratcliffe, Anthony; Pinney, R. Emmett, Conditioned cell culture medium compositions and methods of use.
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  16. Naughton, Gail K.; Horwitz, David L.; Applegate, Mark A.; Zeltinger, Joan; Mansbridge, Jonathan N.; Kern, Andreas; Landeen, Lee K.; Ratcliffe, Anthony; Pinney, R. Emmett, Conditioned cell culture medium compositions and methods of use.
    상세보기
  17. Naughton, Gail K.; Horwitz, David L.; Applegate, Mark; Zeltinger, Joan; Mansbridge, Jonathan; Kern, Andreas; Landeen, Lee K.; Ratcliffe, Anthony; Pinney, R. Emmett, Conditioned cell culture medium compositions and methods of use.
    상세보기
  18. Humes,H. David; Fissell,William H.; Buffington,Deborah A.; Tziampazis,Evangelos, Device for maintaining vascularization near an implant.
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  19. Day, Thomas E.; Jung, Steven B.; Bagga, Charanpreet S., Dynamic bioactive nanofiber scaffolding.
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  20. Day, Thomas E.; Jung, Steven B.; Bagga, Charanpreet S., Dynamic bioactive nanofiber scaffolding.
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  21. Sortwell,Caryl E.; Collier,Timothy J., Erythropoietin administration to improve graft survival.
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  22. Altman, Gregory H.; Kaplan, David L.; Horan, Rebecca L.; Horan, David J., Helically organized silk fibroin fiber bundles for matrices in tissue engineering.
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  23. Kamath, Apurv U.; Yang, Richard C.; Leach, Jacob S.; Quintana, Nelson, Integrated medicament delivery device for use with continuous analyte sensor.
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  24. Kamath, Apurv Ullas; Yang, Richard C.; Leach, Jacob S.; Quintana, Nelson, Integrated medicament delivery device for use with continuous analyte sensor.
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  25. Shults, Mark C.; Rhodes, Rathburn K.; Updike, Stuart J.; Brauker, James H., Low oxygen in vivo analyte sensor.
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  26. Shults, Mark C.; Rhodes, Rathburn K.; Updike, Stuart J.; Brauker, James H., Low oxygen in vivo analyte sensor.
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  27. Shults, Mark; Rhodes, Rathbun K.; Updike, Stuart J.; Brauker, James H., Low oxygen in vivo analyte sensor.
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  28. Shults, Mark; Rhodes, Rathburn K.; Updike, Stuart J.; Brauker, James H., Low oxygen in vivo analyte sensor.
    상세보기
  29. Frondoza, Carmelita G.; Hungerford, David S.; Shikani, Alan H.; Domb, Abraham J.; Fink, David J.; Bloom, Leonard, Method for composite cell-based implants.
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  30. Frondoza, Carmelita G.; Fink, David J.; Hungerford, David S.; Shikani, Alan H., Method for fabricating cell-containing implants.
    상세보기
  31. Humes,H. David, Method of modulating inflammatory response.
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  32. Beaulieu, Andre; Paquin, Robert, Method of producing concentrated non-buffered solutions of fibronectin.
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  33. Myles, Arthur; Ilsley, Stephen R.; Mannuzza, Frank J., Method of providing a substrate with a ready-to-use, uniformly distributed extracellular matrix.
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  34. Staas, Jay K.; Tice, Thomas R.; Hudson, Bruce W.; Tipton, Arthur J., Methods for manufacturing delivery devices and devices thereof.
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  35. Murphy, William L.; Peters, Martin C.; Mooney, David J., Mineralization and biological modification of biomaterial surfaces.
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  36. Murphy, William L.; Peters, Martin C.; Mooney, David J.; Kohn, David H., Mineralization and biological modification of biomaterial surfaces.
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  37. Murphy, William L.; Peters, Martin C.; Mooney, David J.; Kohn, David H., Mineralization and biological modification of biomaterial surfaces.
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  38. Herlyn,Meenhard; Kalabis,Jiri, Organotypic intestinal culture and methods of use thereof.
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  39. Mortarino, Enrico; Akers, Jessica L., Pliable silk medical device.
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  40. Shapiro, Lilia; Glicklis, Rachel; Cohen, Smadar, Polysaccharide sponges for cell culture and transplantation.
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  41. Biggs, Danielle; Nettles, Heather, Process for preparing microparticles having a low residual solvent volume.
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  42. Samuel Asculai CA; Bruno Giannetti DE, Reinforced matrices.
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  43. Beaulieu,Andre; Paquin,Robert; Lariviere,Benoit, Solid wound healing formulations containing fibronectin.
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  44. Shea,Lonnie D.; Bonadio,Jeffrey; Mooney,David J.; Peters,Martin C., Sustained DNA delivery from structural matrices.
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  45. Berkland, Cory; Stehno-Bittel, Lisa A.; Siahaan, Teruna; Ramachandran, Karthik, Templated islet cells and small islet cell clusters for diabetes treatment.
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  46. Fette, Clay, Tissue-based compositions.
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  47. Brister, Mark; Neale, Paul V.; Brauker, James H.; Thrower, James Patrick, Transcutaneous analyte sensor.
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  48. Brister, Mark; Neale, Paul V.; Brauker, James; Thrower, James Patrick, Transcutaneous analyte sensor.
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  49. Brister, Mark; Neale, Paul V.; Saint, Sean; Petisce, James R.; Thrower, James Patrick; Kamath, Apurv Ullas; Kline, Daniel S.; Guerre, John A.; Codd, Daniel Shawn; McGee, Thomas F.; Petersen, David Michael, Transcutaneous analyte sensor.
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  50. Grogan, Shawn P.; Mainil-Varlet, Pierre; Müller, Werner; Schaffner, Thomas, Transplant/implant device and method for its production.
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  51. Lucas, John; Briggs, Kristen, Use of adipsin/complement factor D in the treatment of metabolic related disorders.
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