초록

The present invention discloses applicators containing cationic surface active agents, hydrophobic barrier-forming materials and antimicrobial compounds which form, upon application to dental surfaces, a protective and bacteria-inhibiting film.

대표청구항 ▼

[ What is claimed as new and desired to be secured by Letters Patent of the United States is:] [1.] A composition, comprising:(a) 1 to 20 wt. %, based on the total weight of (a) and (b), of a transfer agent; and(b) 80 to 99 wt. %, based on the total weight of (a) and (b), of a barrier material;where

[ What is claimed as new and desired to be secured by Letters Patent of the United States is:] [1.] A composition, comprising:(a) 1 to 20 wt. %, based on the total weight of (a) and (b), of a transfer agent; and(b) 80 to 99 wt. %, based on the total weight of (a) and (b), of a barrier material;wherein said transfer agent is selected from the group consisting of compounds of the formulae (I), (II), and (III): [ STR 2 ] wherein R is a C.sub.8-20 alkyl chain which may be substituted with one or more hydroxy groups, R', R", and R'" each independently are a C.sub.8-20 alkyl chain which may be substituted with one or more hydroxy groups, a C.sub.1-4 alkyl group which may be substituted with one or more hydroxy groups, a C.sub.6-10 aryl group, or hydrogen, and X is fluoride or chloride; laurylpyridinium chloride; laurylpyridinium bromide; cetylpyridinium chloride; cetylpyridinium bromide; cetylpyridinium fluoride; petroleum derived cationics; polydimeryl polyamines; polydiallyl dimethylammonium chlorides, polyhexamethylene biguanides; 1,5-dimethyl-1,5-diazaundecamethylene polymethobromide; polyvinylpyrrolidones; polypeptides; poly(allylamine)hydrochloride; polyoxyethylenated amines; acylated polyethyleneimines; diethylaminoethyl cellulose; poly(vinyl-benzylstearylbetaine); poly(vinyl-benzylmethyllaurylammonium chloride); poly(vinyl-benzyllaurylpyridylpyridinium chloride); poly(vinyl-benzylcetylammonylhexyl ether); compounds of the formula RN(CH.sub.3)[(C.sub.2 H.sub.4 O).sub.x H].sub.2 (+) A(-), where A(-) is chloride or fluoride, X is a number from 1 to 20, and R is a C.sub.8-22 alkyl group; polyacrylamide in which 5 to 95 mole % of the nitrogen atoms have been derivatized by reaction with a C.sub.8-20 fatty acid halide and 5 to 95 mole % of the nitrogen atoms have been quaternized with HF; polyvinylpyridine in which 5 to 95 mole % of the nitrogen atoms have been derivatized by reaction with a C.sub.8-20 fatty acid halide and 5 to 95 mole % of the nitrogen atoms have been quaternized with HF; and 5-amino-1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidine; andwherein said barrier material is selected from the group consisting of beeswax, lanolin, spermaceti, carnauba wax, paraffin waxes, microcrystalline waxes, petrolatum waxes, ethylenic polymer waxes, polymethylene waxes, polymethylalkylsiloxane, polydimethylsiloxane, poly(perfluoroalkylmethyl siloxane), poly(methyl-3,3,3-trifluoropropyl siloxane), polytetrafluoroethylene, fluorinated polyethylene-propylene, polyvinylidene fluoride, and polyvinylfluoride,wherein, when said composition is applied to a surface of a tooth, said composition forms a coating on said surface of said tooth in which said transfer agent binds electrostatically to said surface of said tooth and said barrier material binds to said transfer agent electrostatically bound to said surface of said tooth, and said coating conforms to and fills pits, fissures, cracks, and irregularities present on said surface of said tooth.