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Solid matrix system for transdermal drug delivery 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-013/02
출원번호 US-0803979 (1997-02-21)
발명자 / 주소
  • Chiang Chia-Ming
  • Tenzel Renee Ann
출원인 / 주소
  • Cygnus, Inc.
대리인 / 주소
    Horne
인용정보 피인용 횟수 : 15  인용 특허 : 40

초록

A matrix for containing drugs for transdermal delivery systems is disclosed. The matrix formed of a skin-adhesive acrylate copolymer, attains high rates of drug delivery without the addition of drug delivery rate enhancers. In preferred embodiments the matrix is used to administer steroids, in parti

대표청구항

[ What is claimed is:] [1.] A drug-containing matrix for use in a transdermal drug delivery device for administering at least one estrogen to an area of skin or mucosa comprising the drug dispersed in a body of a pressure sensitive adhesive, said pressure-sensitive adhesive comprising an acrylate co

이 특허에 인용된 특허 (40)

  1. Martens John A. (White Bear Lake MN) Clemens Lawrence M. (Minneapolis MN) Zigman Alvin R. (Woodbury MN), Acrylic-type pressure sensitive adhesives by means of ultraviolet radiation curing.
  2. Marecki Nelda M. (Plainfield NJ) Avalon Gary A. (Painesville OH), Bandage for sustained delivery of drugs.
  3. Reul Bernhard (Knigstein DEX) Hiller Dietrich (Wiesbaden DEX), Depot body on the basis of silicone rubber and process for the preparation thereof.
  4. Campbell, Patricia S.; Chandrasekaran, Santosh K., Dosage for coadministering drug and percutaneous absorption enhancer.
  5. Kim Benjamin K. (Toms River NJ), Estradiol transdermal delivery system.
  6. Hoffmann Hans-Rainer (Neuwied DEX) Klein Robert P. (Neuwied DEX) Meconi Reinhold (Neuwied DEX) Cordes Gunter (Leichingen DEX) Wolff Hans M. (Monheim DEX), Estrogen-containing active substance plaster.
  7. Otsuka Saburo (Osaka JPX) Yoshikawa Toshiyuki (Osaka JPX) Tokuda Shoichi (Osaka JPX) Ito Yuusuke (Osaka JPX), Hydrophilic therapeutic material.
  8. Inaba, Kohji; Sasatani, Seiei; Koide, Tatsushi; Nanya, Tamio, Long-lasting multi-layered film preparation.
  9. Roos Eric J. (Marlborough MA) Chiang Chia-Ming (Foster City CA) Hsu Tsung-Min (Taipei TWX), Low flux matrix system for delivering potent drugs transdermally.
  10. Kim Jung J. (Anyang-shi KRX) Lee Woo Y. (Anyang-shi KRX) Ahn Jong W. (Seoul KRX) Han Sang H. (Suwon-shi KRX), Medicinal adhesive for percutaneous administration.
  11. Ebert Charles D. (Salt Lake City UT) Patel Dinesh (Murray UT) Heiber Werner (Salt Lake City UT), Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective level.
  12. Cilento Rodolfo D. (North Brunswick NJ) Frank Margaret A. (Lawrenceville NJ) Fairbrother John E. (Wales NJ GBX) Freeman Frank M. (Lawrenceville NJ), Method of preparing adhesive dressings containing a pharmaceutically active ingredient.
  13. Lloyd Ronald (Sawbridgeworth GB2) Metcalfe Peter J. (Stansted Mountfitchet GB2), Moisture vapor transmitting film of polyurethane blended with an incompatible polymer.
  14. Campbell Patricia S. (Palo Alto CA) Chandrasekaran Santosh K. (Palo Alto CA), Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer.
  15. Nakagawa Takashi (Otsu JPX) Kurono Masayasu (Mie JPX) Sato Makoto (Aichi JPX) Ishida Tsutomu (Iwakura JPX) Tokita Kazushi (Aichi JPX) Takahashi Katsuhiko (Aichi JPX) Azuma Masato (both Osaka JPX) Uen, Percutaneous-administration-type pharmaceutical preparation of nitroglycerin.
  16. Keith Alec D. (Miami FL) Snipes Wallace (State College PA), Polymeric diffusion matrix containing estrogens.
  17. Ito Toshio (Sekimachi JPX) Ninomiya Hiroshi (Sayama JPX) Yamagami Kunio (Naruto JPX), Pressure-sensitive adhesive tape or pressure-sensitive adhesive sheet containing nitroglycerin.
  18. Kigasawa Kazuo (Tokyo JPX) Ohtani Hideaki (Tokyo JPX) Tanaka Makoto (Tokyo JPX) Hayashida Shigeru (Tokyo JPX), Soft patch.
  19. Chiang Chia-Ming (Foster City CA) Tenzel Renee A. (Mountain View CA), Solid matrix system for transdermal drug delivery.
  20. Miranda Jesus (Miami FL) Sablotsky Steven (Miami FL), Solubility parameter based drug delivery system and method for altering drug saturation concentration.
  21. Chien Yie W. (North Brunswick NJ) Lee Chia-Shun (Highland Park NJ) Valia Kirti H. (Indianapolis IN) Chien Te-Yen (Piscataway NJ), Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration.
  22. Chien Yie W. (North Brunswick NJ) Chien Te-Yen (Branchburg NJ), Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration.
  23. Chien Yie W. (N. Brunswick NJ) Chein Te-Yen (Branchburg NJ), Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process.
  24. Sablotsky Steven (Miami FL), Transdermal acrylic multipolymer drug delivery system.
  25. Sharma Kuldeepak (Mountain View CA) Roy Samir D. (Mountain View CA) Roos Eric J. (Redwood City CA), Transdermal administration of buprenorphine.
  26. Gale Robert M. (Los Altos CA) Nedberge Diane E. (Los Altos CA) Atkinson Linda E. (Portola Valley CA), Transdermal contraceptive formulations, methods and devices.
  27. Nuwayser Elie S. (Wellesley MA), Transdermal drug delivery system.
  28. Cordes Gnter (Kurlandweg 13 D-5653 Leichlingen DEX) Wolff Michael (Mozartstr. 28 D-4019 Monheim DEX), Transdermal drug patches.
  29. Nelson Gregory R. (St. Paul MN) Zerbe Horst-Georg (St. Paul MN) Moore Cheryl L. (St. Paul MN) Wick Steven M. (St. Paul MN), Transdermal estradiol delivery system.
  30. Chien Yie W. (North Brunswick NJ) Chien Te-Yen (Branchburg NJ), Transdermal estrogen/progestin dosage unit, system and process.
  31. Chien Yie W. (North Brunswick NJ) Chien Te-Yen (Piscataway NJ) Huang Yih-Chain (Piscataway NJ), Transdermal estrogen/progestin dosage unit, system and process.
  32. Chien Yie W. (North Brunswick NJ) Chien Te-Yen (Branchburg NJ) Huang Yih-Chain (Piscataway NJ), Transdermal fertility control system and process.
  33. Chien Yie W. (North Brunswick NJ) Chien Te-Yen (Piscataway NJ) Huang Yih-Chain (Piscataway NJ), Transdermal fertility control system and process.
  34. Gale Robert M. (Los Altos CA) Nedberge Diane E. (Los Altos CA) Atkinson Linda E. (Portola Valley CA), Transdermal formulations, methods and devices.
  35. Casper Robert F. (Toronto CAX), Transdermal hormone replacement therapy.
  36. Hyon Suong-Hyu (Uji JPX) Ikada Yoshito (Uji JPX), Transdermal therapeutic composition.
  37. Yamada Masayuki (Kawanishi JPX) Nonomura Muneo (Suita JPX) Nishikawa Kohei (Kyoto JPX), Transdermal therapeutic composition.
  38. Cordes Gunter,DEX ; Rovati Lucio C.,ITX, Transdermal therapeutic system for application of pharmaceuticals onto the skin.
  39. Zupan, Jacob A., Use of eucalyptol for enhancing skin permeation of bio-affecting agents.
  40. Shah Kishore R. (Chelmsford MA), Water vapor permeable pressure sensitive adhesives incorporating modified acrylate copolymers.

이 특허를 인용한 특허 (15)

  1. Kamiyama, Fumio, Block copolymer.
  2. Ye, Hai; Buckley, Christopher David; Yue, Jiang, Delivery system for oral care compositions comprising organosiloxane resins using a removable backing strip.
  3. Breitenbach, Armin, Device for the transdermal administration of a rotigotine base.
  4. Ebert, Charles; Hoel, Gary; Anigbogu, Angela; Roy, Samir, Formulations and methods for providing progestin-only contraception while minimizing adverse side effects associated therewith.
  5. Breitenbach, Armin; Wolff, Hans-Michael, Hot melt TTS for administering rotigotine.
  6. Breitenbach, Armin; Wolff, Hans-Michael, Hot-melt TTS for administering rotigotine.
  7. Rimpler,Stephan; Grapatin,Sabine; Krein,Cliff; Thelen,Markus, Injectable pharmaceutical composition for systematic administration of pharmacologically active ingredients.
  8. Li, Gai Ling; Bouwstra, Johanna Aaltje; Wolff, Hans Michael; Nugroho, Akhmad Karis, Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease.
  9. McGuire, Jr., James E.; Strange, Andrew C.; Lamone, Daniel E., Method and apparatus for continuous production of partially polymerized compositions and polymers therefrom.
  10. McGuire, Jr., James E.; Strange, Andrew C.; Lamone, Daniel E., Method for continuous production of (meth)acrylate syrup and adhesives therefrom.
  11. Sagel, Paul Albert; Nguyen, Lan Ngoc; Washington, Randy Purnell, Tooth whitening product.
  12. Schacht, Dietrich Wilhelm; Hannay, Mike; Wolff, Hans-Michael, Transdermal delivery system.
  13. Schacht, Dietrich Wilhelm; Hannay, Mike; Wolff, Hans-Michael, Transdermal delivery system for the administration of rotigotine.
  14. Schacht, Dietrich Wilhelm; Hannay, Mike; Wolff, Hans-Michael, Transdermal delivery system for the administration of rotigotine.
  15. Müller, Walter; Peck, James V., Transdermal therapeutic system and method of use thereof for treating parkinsonism.
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