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| 국가/구분 | United States(US) Patent 등록 |
|---|---|
| 국제특허분류(IPC7판) |
|
| 출원번호 | US-0829685 (1997-03-31) |
| 발명자 / 주소 |
|
| 출원인 / 주소 |
|
| 대리인 / 주소 |
|
| 인용정보 | 피인용 횟수 : 372 인용 특허 : 139 |
Methods are provided for inhibiting stenosis or restenosis following vascular trauma in a mammalian host, comprising administering to the host a therapeutically effective dosage of a cytostatic agent and/or cytoskeletal inhibitor so as to biologically stent the traumatized vessel. Also provided is a
Methods are provided for inhibiting stenosis or restenosis following vascular trauma in a mammalian host, comprising administering to the host a therapeutically effective dosage of a cytostatic agent and/or cytoskeletal inhibitor so as to biologically stent the traumatized vessel. Also provided is a method to inhibit or reduce vascular remodeling following vascular trauma, comprising administering an effective amount of a cytoskeletal inhibitor. Further provided are pharmaceutical compositions and kits comprising the therapeutic agents of the invention.
[ What is claimed is:] [1.] A therapeutic method comprising administering to a mammalian blood vessel a dosage form comprising a cytoskeletal inhibitor effective to inhibit or reduce diminution in vessel lumen area of the mammalian blood vessel, wherein the cytoskeletal inhibitor is in substantially
[ What is claimed is:] [1.] A therapeutic method comprising administering to a mammalian blood vessel a dosage form comprising a cytoskeletal inhibitor effective to inhibit or reduce diminution in vessel lumen area of the mammalian blood vessel, wherein the cytoskeletal inhibitor is in substantially crystalline form and wherein the crystals are of a size which results in sustained release of the cytoskeletal inhibitor.
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