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erbB-2 gene segments, probes, recombinant DNA and kits for detection 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
출원번호 US-0475035 (1995-06-07)
발명자 / 주소
  • King C. Richter
  • Kraus Matthias H.
  • Aaronson Stuart A.
출원인 / 주소
  • The United States of America as represented by the Department of Health and Human Services
대리인 / 주소
    Needle & Rosenberg, P.C.
인용정보 피인용 횟수 : 73  인용 특허 : 2

초록 ▼

The isolation, cloning and characterization of a human gene related to but distinct from the EGF receptor gene has been described. Nucleotide sequence of the gene and amino acid sequence of the polypeptide encoded by the gene have been determined. The use of the nucleic acid probes and antibodies ha

대표청구항 ▼

[ We claim:] [1.] A purified nucleic acid which specifically hybridinzes to at least part of a MAC117 gene or nucleic acid derivative thereof and which does not hybridize to a nucleic acid encoding epidermal growth factor receptor under stringent conditions, wherein said MAC117 gene comprises the fo

이 특허에 인용된 특허 (2)

  1. Slamon Dennis J. (Woodland Hills CA) McGuire William L. (San Antonio TX), Determination of status in neoplastic disease.
    상세보기
  2. Frankel Arthur E. (Palo Alto CA) Ring David B. (Redwood City CA) Bjorn Michael J. (Hercules CA), Monoclonal anti-human breast cancer antibodies.
    상세보기

이 특허를 인용한 특허 (73)

  1. Bryant, John L., Adjuvant therapy with an anti-ERBB2 antibody conjugated to a maytansiniod.
    상세보기
  2. Bryant, John L., Anti-ERBB2 antibody adjuvant therapy.
    상세보기
  3. Fendly,Brian M., Anti-ErbB2 antibodies.
    상세보기
  4. Majumdar,Adhip P. N.; Sarkar,Fazlul H., Antibodies to a novel EGF-receptor related protein (ERRP).
    상세보기
  5. Clinton, Gail M., Compositions and methods for treating cancer by modulating HER-2 and EGF receptors.
    상세보기
  6. Clinton,Gail M., Compositions and methods for treating cancer by modulating HER-2 and EGF receptors.
    상세보기
  7. Cheever, Martin A; Disis, Mary L, Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated.
    상세보기
  8. Cheever, Martin A; Disis, Mary L, Compounds for eliciting or enhancing immune reactivity to HER-2/protein for prevention or treatment of malignancies in which the HER-2/oncogene is associated.
    상세보기
  9. Mass, Robert D., Detection of ErbB2 gene amplification to increase the likelihood of the effectiveness of ErbB2 antibody breast cancer therapy.
    상세보기
  10. Baughman, Sharon A.; Shak, Steven, Dosages for treatment with anti-ErbB2 antibodies.
    상세보기
  11. Baughman,Sharon A.; Shak,Steven, Dosages for treatment with anti-ErbB2 antibodies.
    상세보기
  12. Freeman, Daniel J; Juan, Todd; Radinsky, Robert, Epidermal growth factor receptor mutations.
    상세보기
  13. Quinn, Thomas P.; Karasseva, Natalia G., Erb-2 receptor targeting peptide.
    상세보기
  14. Quinn, Thomas P.; Karasseva, Natalia G., ErbB-2 receptor targeting peptide.
    상세보기
  15. Baker, Joffre B.; Bryant, John L.; Paik, Soonmyung; Shak, Steven, Expression profile algorithm and test for cancer prognosis.
    상세보기
  16. Derynck, Mika K.; Kelsey, Stephen M., Extending time to disease progression or survival in cancer patients.
    상세보기
  17. Allison, David E.; Bruno, Rene; Lu, Jian-Feng; Ng, Chee M., Fixed dosing of HER antibodies.
    상세보기
  18. Allison,David E.; Bruno,Rene; Lu,Jian Feng; Ng,Chee M., Fixed dosing of HER antibodies.
    상세보기
  19. Mass, Robert D., Gene detection assay for improving the likelihood of an effective response to a HER2 antibody cancer therapy.
    상세보기
  20. Mass, Robert D., Gene detection assay for improving the likelihood of an effective response to a HER2 antibody cancer therapy.
    상세보기
  21. Mass, Robert D., Gene detection assay for improving the likelihood of an effective response to an EGFR antagonist cancer therapy.
    상세보기
  22. Cobleigh, Melody A.; Shak, Steve; Baker, Joffre B.; Cronin, Maureen T., Gene expression markers for breast cancer prognosis.
    상세보기
  23. Cobleigh, Melody A.; Shak, Steve; Baker, Joffre B.; Cronin, Maureen T., Gene expression markers for breast cancer prognosis.
    상세보기
  24. Cobleigh, Melody A.; Shak, Steve; Baker, Joffre B.; Cronin, Maureen T., Gene expression markers for breast cancer prognosis.
    상세보기
  25. Cobleigh, Melody A.; Shak, Steven; Baker, Joffre B.; Cronin, Maureen T., Gene expression markers for breast cancer prognosis.
    상세보기
  26. Cobleigh, Melody A.; Shak, Steven; Baker, Joffre B.; Cronin, Maureen T., Gene expression markers for breast cancer prognosis.
    상세보기
  27. Baker, Joffre B.; Shak, Steven; Gianni, Luca, Gene expression markers for predicting response to chemotherapy.
    상세보기
  28. Baker, Joffre B.; Shak, Steven; Gianni, Luca, Gene expression markers for predicting response to chemotherapy.
    상세보기
  29. Lee-Hoeflich, Si Tuen; Stern, Howard, Gene expression markers of tumor resistance to HER2 inhibitor treatment.
    상세보기
  30. Baker, Joffre B.; Cronin, Maureen T.; Kiefer, Michael C.; Shak, Steve; Walker, Michael Graham, Gene expression profiling in biopsied tumor tissues.
    상세보기
  31. Baker, Joffre B.; Cronin, Maureen T.; Kiefer, Michael C.; Shak, Steve; Walker, Michael Graham, Gene expression profiling in biopsied tumor tissues.
    상세보기
  32. Baker, Joffre B.; Cronin, Maureen T.; Kiefer, Michael C.; Shak, Steve; Walker, Michael Graham, Gene expression profiling in biopsied tumor tissues.
    상세보기
  33. Baker, Joffre B.; Cronin, Maureen T.; Shak, Steve; Baselga, Jose, Gene expression profiling of EGFR positive cancer.
    상세보기
  34. Baker, Joffre B.; Cronin, Maureen T.; Shak, Steven; Baselga, Jose, Gene expression profiling of EGFR positive cancer.
    상세보기
  35. Clinton, Gail M.; Evans, Adam; Henner, William D., HER-2 binding antagonists.
    상세보기
  36. Doherty,Joni Kristin; Clinton,Gail M.; Adelman,John P., HER-2 binding antagonists.
    상세보기
  37. Wicha, Max S.; Korkaya, Hasan, HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells.
    상세보기
  38. Adams, Camellia W.; Presta, Leonard G.; Sliwkowski, Mark, Humanized anti-ERBB2 antibodies and treatment with anti-ERBB2 antibodies.
    상세보기
  39. Adams, Camellia W.; Presta, Leonard G.; Sliwkowski, Mark, Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies.
    상세보기
  40. Sliwkowski, Mark, Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies.
    상세보기
  41. Cheever, Martin A.; Disis, Mary L., Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated.
    상세보기
  42. Cheever,Martin A; Disis,Mary L, Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated.
    상세보기
  43. Cheever, Martin A; Disis, Mary L, Immune reactivity to HER-2/protein for diagnosis and treatment of malignancies in which the HER-2/oncogene is associated.
    상세보기
  44. Kuriyan, John; Zhang, Xuewu; Cole, Philip, Inhibitors of the EGFR kinase targeting the asymmetric activating dimer interface.
    상세보기
  45. Baker, Joffre B.; Bryant, John L.; Paik, Soonmyung; Shak, Steven, Molecular indicators of breast cancer prognosis and prediction of treatment response.
    상세보기
  46. Hudziak Robert M. ; Shepard H. Michael ; Ullrich Axel ; Fendly Brian M., Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  47. Robert M. Hudziak ; H. Michael Shepard ; Axel Ullrich ; Brian M. Fendly, Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  48. Robert M. Hudziak ; H. Michael Shepard ; Axel Ullrich ; Brian M. Fendly, Monoclonal antibodies directed to the HER2 receptor.
    상세보기
  49. Amler, Lukas C.; Birkner, Merrill; Lin, Chin-Yu; Moecks, Joachim; Strauss, Andreas, Predicting response to a HER inhibitor.
    상세보기
  50. Amler, Lukas C.; Birkner, Merrill; Lin, Chin-Yu; Moecks, Joachim; Strauss, Andreas, Predicting response to a HER inhibitor.
    상세보기
  51. Baker, Joffre B.; Bryant, John L.; Paik, Soonmyung; Shak, Steven, Predicting response to chemotherapy using gene expression markers.
    상세보기
  52. Baker, Joffre B.; Bryant, John L.; Paik, Soonmyung; Shak, Steven, Prediction of likelihood of cancer recurrence.
    상세보기
  53. Andya, James; Cleland, Jeffrey L.; Hsu, Chung C.; Lam, Xanthe M.; Overcashier, David E.; Shire, Steven J.; Yang, Janet Yu-Feng; Wu, Sylvia Sau-Yan, Protein formulation.
    상세보기
  54. Andya, James; Cleland, Jeffrey L.; Hsu, Chung C.; Lam, Xanthe M.; Overcashier, David E.; Shire, Steven J.; Yang, Janet Yu-Feng; Wu, Sylvia Sau-Yan, Protein formulation.
    상세보기
  55. Andya, James; Cleland, Jeffrey L.; Hsu, Chung C.; Lam, Xanthe M.; Overcashier, David E.; Shire, Steven J.; Yang, Janet Yu-Feng; Wu, Sylvia Sau-Yan, Protein formulation.
    상세보기
  56. Andya,James; Cleland,Jeffrey L.; Hsu,Chung C.; Lam,Xanthe M.; Overcashier,David E.; Shire,Steven J.; Yang,Janet Yu Feng; Wu,Sylvia Sau Yan, Protein formulation.
    상세보기
  57. Cleland, Jeffrey L.; Hsu, Chung C.; Lam, Xanthe M.; Overcashier, David E.; Yang, Janet Yu-Feng, Protein formulation.
    상세보기
  58. Majumdar, Adhip P. N., Recombinant DNA encoding an epidermal growth factor receptor related protein.
    상세보기
  59. Andya, James; Hsu, Chung C.; Shire, Steven J.; Wu, Sylvia Sau-Yan, Treating a mammal with a formulation comprising an antibody which binds IgE.
    상세보기
  60. Sliwkowski,Mark X., Treating prostate cancer with anti-ErbB2 antibodies.
    상세보기
  61. Baughman, Sharon A.; Shak, Steven, Treatment with anti-ErbB2 antibodies.
    상세보기
  62. Hellmann, Susan D., Treatment with anti-ErbB2 antibodies.
    상세보기
  63. Hellmann, Susan D., Treatment with anti-ErbB2 antibodies.
    상세보기
  64. Hellmann, Susan D., Treatment with anti-ErbB2 antibodies.
    상세보기
  65. Hellmann, Susan D., Treatment with anti-ErbB2 antibodies.
    상세보기
  66. Hellmann, Susan D., Treatment with anti-ErbB2 antibodies.
    상세보기
  67. Paton, Virginia E.; Shak, Steven; Hellmann, Susan D., Treatment with anti-ErbB2 antibodies.
    상세보기
  68. Sliwkowski, Mark, Treatment with anti-ErbB2 antibodies and EGFR-targeted drugs.
    상세보기
  69. Adams,Camellia W.; Presta,Leonard G.; Sliwkowski,Mark, Treatment with anti-ErbB2 antibodies and anti-hormonal compounds.
    상세보기
  70. Adams,Camellia W.; Presta,Leonard G.; Sliwkowski,Mark, Treatment with anti-ErbB2 antibodies and chemotherapeutic agents.
    상세보기
  71. Adams,Camellia W.; Presta,Leonard G.; Sliwkowski,Mark, Treatment with anti-ErbB2 antibody combinations.
    상세보기
  72. Kiefer, Michael C.; Hoyt, Kenneth W., Universal amplification of fragmented RNA.
    상세보기
  73. Scott, Randy; Baker, Joffre B.; Kiefer, Michael C., Use of intronic RNA to measure gene expression.
    상세보기

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