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Spray-dried microparticles and their use as therapeutic vehicles 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/43
  • A61K-009/14
  • A61K-009/50
출원번호 US-0487420 (1995-06-07)
우선권정보 EP-0307126 (1994-09-29)
발명자 / 주소
  • Sutton Andrew D.,GBX
  • Johnson Richard A.,GBX
  • Senior Peter J.,GBX
  • Heath David,GBX
출원인 / 주소
  • Quadrant Healthcare (UK) Limited, GBX
대리인 / 주소
    Sterne, Kessler, Goldstein & Fox P.L.L.C.
인용정보 피인용 횟수 : 184  인용 특허 : 41

초록

Microparticles of a water-soluble material, which are smooth and spherical, and at least 90% of which have a mass median particle size of 1 to 10 .mu.m, and which carry a therapeutic or diagnostic agent can successfully be used in dry powder inhalers to deliver the said agent.

대표청구항

[ What we claim is:] [2.] A composition of matter, comprising substantially dry, discrete microparticles having a solid wall formed of a non-denatured, water-soluble wall-forming material, wherein said microparticles are hollow and substantially smooth and spherical, wherein at least 90% of said mic

이 특허에 인용된 특허 (41)

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  37. Erbel Raimund (Mainz DEX) Zotz Rainer (Mainz DEX) Krone Volker (Flrsheim DEX) Magerstdt Michael (Hofheim am Taunus DEX) Walch Axel (Frankfurt am Main DEX), Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents.
  38. Erbel Raimund (Mainz DEX) Zotz Rainer (Mainz DEX) Krone Volker (Flrsheim DEX) Magerstdt Michael (Hofheim am Taunus DEX) Walch Axel (Frankfurt am Main DEX), Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents.
  39. Erbel Raimund (Mainz) Zotz Rainer (Mainz) Krone Volker (Flrsheim) Magerstdt Michael (Hofheim am Tanus) Walch Axel (Frankfurt am Main DEX), Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents.
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