초록 ▼

An ultrasound delivery catheter equipped and configured for concurrent delivery of drugs or therapeutic agents. The catheter comprises an elongate pliable catheter body having an ultrasound delivery member or wire extending longitudinally therethrough. A drug/therapeutic agent infusion lumen also ex

An ultrasound delivery catheter equipped and configured for concurrent delivery of drugs or therapeutic agents. The catheter comprises an elongate pliable catheter body having an ultrasound delivery member or wire extending longitudinally therethrough. A drug/therapeutic agent infusion lumen also extends longitudinally through the body of the catheter and opens distally through one or more outflow apertures at or near the distal end of the catheter body. The drug/therapeutic agent outflow apertures are preferably positioned and configured to cause the drug or therapeutic agent to flow in direction(s) non-parallel to the longitudinal axis of the catheter. The delivery of ultrasound through the catheter, concurrent with infusion of drug or therapeutic agent therethrough, will cause the drug or therapeutic agent to be disseminated or dispersed by the ultrasonic vibration or movement at the distal end of the catheter.

대표청구항 ▼

[ What is claimed is:] [1.] An ultrasound delivery/medicament infusion catheter for delivering ultrasonic energy to a treatment location within a mammalian body concomitantly with an infusion of medicament, said catheter comprising:an elongate flexible catheter body having a longitudinal axis, a pro

[ What is claimed is:] [1.] An ultrasound delivery/medicament infusion catheter for delivering ultrasonic energy to a treatment location within a mammalian body concomitantly with an infusion of medicament, said catheter comprising:an elongate flexible catheter body having a longitudinal axis, a proximal end, a distal end, an outer surface, and at least one hollow lumen extending longitudinally therethrough;an ultrasound distal tip member disposed at the distal end of the catheter body;an ultrasound transmission member extending longitudinally through said catheter body and being connected at the distal end thereof to the distal tip member, said ultrasound transmission member being coupleable to an ultrasound source such that ultrasonic vibration from said ultrasound source may be transmitted through said ultrasound transmission member to the ultrasonic distal tip member at the distal end of said catheter;a medicament inlet formed near the proximal end of said catheter body for infusing a liquid medicament through a hollow lumen of said catheter; andat least one medicament outlet aperture formed in the distal tip member and oriented radially outward in relation to the longitudinal axis of the catheter body and in fluid communication with the medicament inlet through the hollow lumen to permit medicament to flow out of said catheter generally along the radial direction;whereby liquid medicament may be infused through said catheter, and out of said medicament outlet aperture(s), concurrently with the delivery of ultrasonic energy to the distal end of the catheter.