초록 ▼

An intradermal drug delivery device comprises a housing (301a, 301b) having a drug reservoir (312) therewithin and a gas generation chamber (313) separated from the reservoir (312) by a displaceable membrane (311). A microprocessor-controlled electrolytic cell (316a, 316b, 319) provides gas to expan

An intradermal drug delivery device comprises a housing (301a, 301b) having a drug reservoir (312) therewithin and a gas generation chamber (313) separated from the reservoir (312) by a displaceable membrane (311). A microprocessor-controlled electrolytic cell (316a, 316b, 319) provides gas to expand the gas generation chamber (313) and thereby contract the reservoir (312). A hollow needle (310), communicating at an inner end thereof with the reservoir (312), extends from a lower surface (308) of the housing (301) such that contraction of the reservoir (312) forces drug to escape therefrom via the needle (310). The device permits delivery of drugs of relatively large molecular weights at slow controllable rates. A displaceable protective cover (303) is mounted in means (307) allowing movement of the cover (303) between extended and retracted positions (305, 306). The cover (303) has an adhesive lower surface (309) for attachment to the skin of a subject. In use, a release liner is removed, the device is pressed against the skin and the cover (303) snaps back to the retracted position (306), the needle (310) thereby piercing the skin. After use the housing (301) is pulled away and the cover (303) snaps to the extended position (306) before detaching from the skin, thus concealing the needle (310) before disposal.

대표청구항 ▼

[ We claim:] [1.] An intradermal drug delivery device for the delivery of at least one drug to a subject via the subject's skin, comprising:(a) a housing having a lower surface;(b) a drug reservoir located with the housing;(c) a cover adjustable engaged with the housing from a first extended positio

[ We claim:] [1.] An intradermal drug delivery device for the delivery of at least one drug to a subject via the subject's skin, comprising:(a) a housing having a lower surface;(b) a drug reservoir located with the housing;(c) a cover adjustable engaged with the housing from a first extended position to a second retracted position such that the cover is proximal to the lower surface of the housing when the cover is retracted and the cover is distal to the lower surface of the housing when the cover is extended;(d) means for affixing the cover in position with the lower surface of the housing in contact with the subject's skin;(e) a single hollow needle fixed to the cover and having a first end in communication with the drug reservoir and and a second end projecting outwards no further than the lower surface of the housing when the cover is extended, and to penetrate through the epidermis and into the dermis when the cover is retracted; and(f) means for actively discharging the drug from the reservoir to the subject's skin via the needle.