초록 ▼

A stentless aortic bioprosthesis having patent, non-ligated coronary artery segments extending therefrom, and methods for surgical replacement of aortic and/or non-aortic (e.g., pulmonary) heart valves with such stentless aortic bioprosthesis. The presence of the patent, non-ligated coronary segment

A stentless aortic bioprosthesis having patent, non-ligated coronary artery segments extending therefrom, and methods for surgical replacement of aortic and/or non-aortic (e.g., pulmonary) heart valves with such stentless aortic bioprosthesis. The presence of the patent, non-ligated coronary segments facilitates end to end anastomosis of the patient's native coronary arteries and/or existing coronary artery bypass grafts to the coronary segments of the bioprosthesis even when such native coronary arteries (or coronary grafts) are too short to reach the wall of the aortic segment of the bioprosthesis. The presence of such patent, non-ligated coronary segments also eliminates the need for removal of a "button" or segment of the native aorta in connection with the native coronary artery segments prior to implantation of the bioprosthesis, and is thus advantageous for patients whose ascending aorta is diseased or otherwise compromised.

대표청구항 ▼

[ What is claimed is:] [1.] A stentless heart valve bioprosthesis comprising:tissue harvested from a mammalian donor animal, said tissue including an aortic segment having a wall, an inflow end, an outflow end, and a lumen extending therethrough and right and left coronary artery segments extending

[ What is claimed is:] [1.] A stentless heart valve bioprosthesis comprising:tissue harvested from a mammalian donor animal, said tissue including an aortic segment having a wall, an inflow end, an outflow end, and a lumen extending therethrough and right and left coronary artery segments extending outwardly from said aortic segment, said coronary artery segments having open coronary lumens which extend longitudinally therethrough, such that some of the blood which enters the lumen of the aortic segment may flow outwardly through said coronary lumens; and,a plurality of valve leaflets disposed within said aortic segment, said valve leaflets being alternately moveable between i) open positions whereby blood is permitted to flow in a first direction through the lumen of said aortic segment; and ii) closed positions whereby blood is prevented from backflowing in a second direction through the lumen of said aortic segment,wherein the bioprosthesis has been subjected to a chemical fixation process comprising placing support members into the coronary lumens during the chemical fixation process.