|국가/구분||United States(US) Patent 등록|
|미국특허분류(USC)||128/200.14 ; 128/200.23 ; 128/204.23 ; 128/203.12|
|발명자 / 주소|
|출원인 / 주소|
|대리인 / 주소||
|인용정보||피인용 횟수 : 151 인용 특허 : 23|
A method of treating human patients is provided by the intrapulmonary delivery of a formulation containing a hematopoietic drug. The formulation is automatically released in an aerosolized form from a hand-held, self-contained, portable device comprised of a means for automatically releasing a measured amount of drug into the inspiratory flow path of a patient in response to information obtained from a means for measuring the inspiratory flow rate and determining the inspiratory volume of a patient. Reproducible dosing is obtained by providing for automa...
[ I claim:] [1.] A method of administering a therapeutically effective amount of a hematopoietic drug to a patient with a hand-held, self-contained, reusable device, the method comprising:(a) determining the patient's inspiratory flow profile based on real time values of both said patient's inspiratory flow rate and inspiratory volume;(b) determining a drug release point of said inspiratory flow profile, wherein at said drug release point said patient's inspiratory flow rate is in a range of about 0.10 to about 2.0 liters/second and inspiratory volume is...