IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0106815
(1998-06-29)
|
우선권정보 |
DE-0027710 (1997-06-30) |
발명자
/ 주소 |
|
출원인 / 주소 |
- Bayer Aktiengesellschaft, DEX
|
대리인 / 주소 |
Brinks Hofer Gilson & Lione
|
인용정보 |
피인용 횟수 :
6 인용 특허 :
3 |
초록
▼
Substituted or unsubstituted cyclohexanones are advantageously prepared by hydrogenation of the corresponding phenols in the presence of a palladium-on-carbon catalyst at from 100 to 250.degree. C. and from 1 to 20 bar of hydrogen pressure if the reaction is carried out in the presence of straight-c
Substituted or unsubstituted cyclohexanones are advantageously prepared by hydrogenation of the corresponding phenols in the presence of a palladium-on-carbon catalyst at from 100 to 250.degree. C. and from 1 to 20 bar of hydrogen pressure if the reaction is carried out in the presence of straight-chain, branched or cyclic alkanes having a boiling point at atmospheric pressure of over 70.degree. C. as solvents. This makes it possible to obtain substituted or unsubstituted cyclohexanones in short hydrogenation times and in high yields using low-toxicity, physically problem-free solvents which are easy to handle from a safety point of view.
대표청구항
▼
[ I claim:] [1.] A process for preparing a cyclohexanone of the formula (I): [ STR 3 ] wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are each, independently of one another, hydrogen, hydroxyl, C.sub.1 -C.sub.10 -alkyl, C.sub.3 -C.sub.6 -cycloalkyl, C.sub.6 -C.sub.10 -aryl, C.sub.6 -C.sub.10
[ I claim:] [1.] A process for preparing a cyclohexanone of the formula (I): [ STR 3 ] wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are each, independently of one another, hydrogen, hydroxyl, C.sub.1 -C.sub.10 -alkyl, C.sub.3 -C.sub.6 -cycloalkyl, C.sub.6 -C.sub.10 -aryl, C.sub.6 -C.sub.10 -aryl--CH.sub.2 --, C.sub.6 -C.sub.10 -aryl--O--, C.sub.1 -C.sub.10 -alkoxy, C.sub.3 -C.sub.8 -cycloalkoxy, C.sub.1 -C.sub.4 -alkylamino, di- C.sub.1 -C.sub.4 -alkylamino, C.sub.1 -C.sub.4 -acylamino, COOR.sup.6 where R.sup.6 is hydrogen or C.sub.1 -C.sub.4 -alkyl or R.sup.7 --CH.sub.2 -- where R.sup.7 is hydroxyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkylamino or di- C.sub.1 -C.sub.4 -alkylamino;comprising:prior to hydrogenating, forming a catalyst mixture of palladium-on-carbon catalyst, a base component, and from 20 to 200 % by weight of water, based on the base component to form a catalyst mixture, andhydrogenating a phenol of the formula (II); [ STR 4 ] wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are defined above, in the presence of the catalyst mixture at from 100 to 250.degree. C. and from 1 to 20 bar of hydrogen pressure and in the presence of straight-chain, branched or cyclic alkanes having a boiling point at atmospheric pressure of over 70.degree. C. as solvents.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.