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Process and composition for cleaning soft tissue grafts optionally attached to bone and soft tissue and bone grafts produced thereby 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61M-031/00
출원번호 US-0895203 (1997-07-16)
발명자 / 주소
  • Wolfinbarger
  • Jr. Lloyd
출원인 / 주소
  • LifeNet Research Foundation
대리인 / 주소
    Hopkins
인용정보 피인용 횟수 : 57  인용 특허 : 4

초록

The invention relates to compositions effective for the cleansing of mammalian soft tissue optionally attached to bones, and particularly the removal of blood deposits and bone marrow therefrom. The compsotions are composed of an aqueous solution containing as its essential ingredients a detergent h

대표청구항

[ What is claimed is:] [1.] A method for producing a soft tissue graft suitable for transplantation into a human, comprising:sonicating said soft tissue with a solvent comprising one or more detergents in an ultrasonic cleaner at a temperature and for a time period effective to produce cleaned soft

이 특허에 인용된 특허 (4)

  1. Elledge David M. (2320 N. Ralph Tucson AZ 85712) Smith Dwain W. (3088 W. Monmouth Tucson AZ 85741), Aseptic cleaning apparatus.
  2. Livesey Stephen A. (Eltham TX AUX) del Campo Anthony A. (Houston TX) Nag Abhijit (Houston TX) Nichols Ken B. (The Woodlands TX) Coleman Christopher (Houston TX), Method for processing and preserving collagen-based tissues for transplantation.
  3. Morse Brenda S. (Chamblee GA) Dioh Clement D. (Marietta GA), Preparation of bone for transplantation.
  4. Morse Brenda S. (Chamblee GA) Shanbrom Edward (Santa Ana CA), Preparation of bone for transplantation.

이 특허를 인용한 특허 (57)

  1. Shi, Yaling, Allografts combined with tissue derived stem cells for bone healing.
  2. Shi, Yaling, Allografts combined with tissue derived stem cells for bone healing.
  3. Bianchi, John R.; Mills, C. Randal; Gorham, P. J.; Esch, Michael; Carter, Kevin C.; Coleman, Pat; Ross, Kevin; Rambo, Harry W.; Jones, Darren G.; Buskirk, Dayna, Assembled implant.
  4. Tian, Bin; Davidson, Jim, Biological tissue for surgical implantation.
  5. Dove, Jeffrey S.; Dobler, Darin P.; Davidson, James A.; Wright, Gregory A., Bioprosthetic tissue with reduced calcification.
  6. Williams, Michelle LeRoux; Mills, Charles Randal; Monroy, Rodney, Cancellous bone treated with collagenase and essentially free of blood cells.
  7. Dove, Jeffery; Dobler, Darin; Davidson, Jim; Wright, Gregory, Capping bioprosthetic tissue to reduce calcification.
  8. Dove, Jeffery; Dobler, Darin; Davidson, Jim; Wright, Gregory A., Capping bioprosthetic tissue to reduce calcification.
  9. Dove, Jeffrey S.; Dobler, Darin P.; Davidson, James A.; Wright, Gregory A., Capping bioprosthetic tissue to reduce calcification.
  10. Dove, Jeffrey S.; Dobler, Darin P.; Davidson, James A.; Wright, Gregory A., Capping bioprosthetic tissue to reduce calcification.
  11. Hopkins, Richard A.; Hoffman-Kim, Diane, Cardiac valve replacement.
  12. Kim, Byoung Suck; Song, Seok Beom; Jeong, Goo Won; Kang, Hyo Jung; Jung, Jae Deuck, Cleaning composition for treating tissue for transplantation derived from human/animal.
  13. Samaniego, Adrian C.; Southard, Matthew J.; Blood, Kenneth; Dempsey, Richard, Composite bone constructs and methods.
  14. Chen, Silvia S.; Qin, Xiaofei; Chen, Jingsong; Wolfinbarger, Jr., Lloyd, Crafting of cartilage.
  15. C. Randal Mills ; John F. Wironen, Cyclic implant perfusion cleaning and passivation process.
  16. Mills, C. Randal; Wironen, John F.; Hanstke, Sean, Cyclic implant perfusion, cleaning and passivation process and implant produced thereby.
  17. Mills, C. Randal; Wironen, John F.; Hanstke, Sean, Cyclic implant perfusion, cleaning and passivation process and implant produced thereby.
  18. Chen, Silvia Sihui; Qin, Xiaofei; Chen, Jingsong; Wolfinbarger, Lloyd; Moore, Mark; Thomas, Rony; Linthurst Jones, Alyce, Devitalization and recellularization of cartilage.
  19. Carpentier, Sophie M.; Carpentier, Alain F., Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability.
  20. Southard, Matthew; Samaniego, Adrian C.; Stevens, Peter J., Fascia fibrous compositions and methods for their use and manufacture.
  21. Mills, C. Randal; Wironen, John F.; Hanstke, Sean; Donda, Russell S.; Grooms, Jamie M., Implant sterilization apparatus.
  22. Marino,James F.; Cornwall,Bryan, Method of packaging a bone allograft intended for a spinal fusion procedure.
  23. Benedict, James J.; Fisher, Frank; Brock, Colin, Method of preparing a bone product by removing cancellous bone matrix.
  24. Tian, Bin; Davidson, Jim, Method of treating glutaraldehyde-fixed pericardial tissue with a non-aqueous mixture of glycerol and a C.
  25. Ronholdt, Chad, Methods for determining microbial contamination of allograft products.
  26. Ronholdt, Chad J., Methods for determining microbial contamination of allograft products.
  27. Davidson, Jim; Dove, Jeff; Dobler, Darin, Methods for pre-stressing and capping bioprosthetic tissue.
  28. Dove, Jeffrey S.; Tod, Tara J., Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates.
  29. Xu, Dengfeng; Dove, Jeffrey S., Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system.
  30. Dove, Jeffrey S.; Tian, Bin; Schneider, Ralph; Cohen, Jeffrey S.; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James M.; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
  31. Dove, Jeffrey S.; Tian, Bin; Schneider, Ralph; Cohen, Jeffrey S.; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James M.; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
  32. Dove, Jeffrey S.; Tian, Bin; Schneider, Ralph; Cohen, Jeffrey S.; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
  33. Dove, Jeffrey S.; Tian, Bin; Schneider, Ralph; Cohen, Jeffrey S.; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
  34. Schneider, Ralph; Tian, Bin; Dove, Jeffrey S.; Cohen, Jeff; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
  35. Tian, Bin; Schneider, Ralph; Dove, Jeffrey S.; Cohen, Jeff; Jankovic, Ivan; Migliazza, John F.; Wright, Gregory A.; Young, James; Campbell, Louis A., Methods of conditioning sheet bioprosthetic tissue.
  36. Southard, Matthew; Peterson, Matthew; Henriod, Nate; Bundy, Robert L., Multi-piece machine graft systems and methods.
  37. Lozier, Antony J.; Murphy, Daniel P., Osteochondral graft delivery device and uses thereof.
  38. Wolfinbarger, Jr., Lloyd; O'Leary, Robert K.; Anderson, Billy G., Plasticized bone and soft tissue grafts and methods of making and using same.
  39. Wolfinbarger, Jr., Lloyd; O'Leary, Robert K.; Anderson, Billy G., Plasticized bone and soft tissue grafts and methods of making and using same.
  40. Wolfinbarger, Jr., Lloyd; O'Leary, Robert K.; Anderson, Billy G., Plasticized bone and soft tissue grafts and methods of making and using same.
  41. Crouch,Katrina; Wolfinbarger,Lloyd; O'Leary,Robert; Ford,Louis, Plasticized bone grafts and methods of making and using same.
  42. Wolfinbarger, Jr., Lloyd; O'Leary, Robert K.; Anderson, Billy G., Plasticized soft tissue grafts, and methods of making and using same.
  43. Mills, C. Randal; Bianchi, John R.; Roberts, Michael R.; Nataraj, Chandrasekaran, Process and apparatus for treating implants comprising soft tissue.
  44. Wolfinbarger, Jr., Lloyd; Lange, Perry; Linhurst, Alyce; Moore, Eric; Nolf, Barry, Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced.
  45. Wolfinbarger, Jr., Lloyd; Lange, Perry; Linthurst Jones, Alyce; Moore, Eric; Nolf, Barry, Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced.
  46. Wolfinbarger, Jr.,Lloyd; Lange,Perry; Linhurst Jones,Alyce; Moore,Eric; Nolf,Barry, Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced.
  47. Wolfinbarger, Jr., Lloyd; Lange, Perry; Linhurst, Alyce; Moore, Eric; Nolf, Barry, Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced.
  48. Wolfinbarger, Jr., Lloyd; Lange, Perry; Linthurst-Jones, Alyce; Moore, Eric; Nolf, Barry, Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced.
  49. Wolfinbarger, Jr., Lloyd; Lange, Perry; Linthurst-Jones, Alyce; Moore, Eric; Nolf, Barry, Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced.
  50. Bleyer, Mark W.; Hiles, Michael C.; Patel, Umesh H., Radiopaque implantable collagenous biomaterial device.
  51. Bleyer, Mark W.; Hiles, Michael C.; Patel, Umesh H., Radiopaque implantable collagenous biomaterial device.
  52. Koltz, Michael L.; Shadeck, Louis M.; Little, II, David John; Norman, Gerould Winthrop; Oliver, Dana A., System and method of bone processing.
  53. Malinin, Theodore I, Tissue allograft sterilization method.
  54. Mills, C. Randal; Wironen, John F.; Hanstke, Sean; Donda, Russell S.; Grooms, Jamie M.; Bianchi, John, Tissue pooling process.
  55. Semler, Eric; Callahan, Alex; Canales, Joed; Carroll, Katrina; Dasgupta, Anouska; Shikhanovich, Roman, Tissue-derived tissuegenic implants, and methods of fabricating and using same.
  56. Carpentier, Alain F.; Carpentier, Sophie; Cunanan, Crystal M.; Quintero, Lillian J.; Helmus, Michael N.; Loshbaugh, Christine; Sarner, H. Chris, Treating biological tissues to mitigate post-implantation calcification.
  57. Carpentier, Sophie M.; Carpentier, Alain F., Treatment of bioprosthetic tissues to mitigate post implantation calcification.
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