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Fluorescent cyanine dyes 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-051/00
  • A61M-036/14
출원번호 US-0781326 (1997-01-10)
발명자 / 주소
  • Little Garrick Murray
  • Raghavachari Ramesh
  • Narayanan Narasimhachari
  • Osterman Harry Leonard
출원인 / 주소
  • Li-Cor Inc.
대리인 / 주소
    Rothwell, Figg, Ernst & Kurz
인용정보 피인용 횟수 : 85  인용 특허 : 11

초록

New fluorescent cyanine dyes are useful as reporter groups for labeling biomolecules.

대표청구항

[ What is claimed is:] [1.] A fluorescent dye having the general formula: [ STR 7 ] wherein R is --NCS, and x and y, independently, are integers between 1 and about 10.

이 특허에 인용된 특허 (11)

  1. Hobbs ; Jr. Frank W. (Wilmington DE) Cocuzza Anthony J. (Wilmington DE), Alkynylamino-nucleotides.
    상세보기
  2. Hobbs ; Jr. Frank W. (Wilmington DE) Trainor George L. (Wilmington DE), Alkynylamino-nucleotides.
    상세보기
  3. Clair Colonel (P.O. Box 94321 Las Vegas NV 89199), Apparatus for magnetically treating a fluid.
    상세보기
  4. Engelhardt Dean (New York NY) Rabbani Elazar (New York NY) Kline Stanley (Brooklyn NY) Stavrianopoulos Jannis G. (New York NY) Kirtikar Dollie (Elmhurst NY), Base moiety-labeled detectable nucleatide.
    상세보기
  5. Haugland Richard P. (Eugene OR) Yue Stephen T. (Eugene OR) Millard Paul J. (Eugene OR) Roth Bruce L. (Corvallis OR), Cyclic-substituted unsymmetrical cyanine dyes.
    상세보기
  6. Selvin Paul R. (Berkeley CA) Hearst John (Berkeley CA), Luminescent lanthanide chelates and methods of use.
    상세보기
  7. Waggoner Alan S. (Pittsburgh PA) Ernst Lauren A. (Pittsburgh PA) Mujumdar Ratnakar B. (Glenshaw PA), Method for labeling and detecting materials employing arylsulfonate cyanine dyes.
    상세보기
  8. Prober James M. (Wilmington DE) Dam Rudy J. (Landenberg PA) Robertson ; Jr. Charles W. (Rockland DE) Hobbs ; Jr. Frank W. (Wilmington DE) Trainor George L. (Glen Mills PA), Method, system and reagents for DNA sequencing.
    상세보기
  9. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Modified nucleotides and methods of preparing and using same.
    상세보기
  10. Cruickshank Kenneth (Lisle IL), Nucleotide compositions with linking groups.
    상세보기
  11. Asai Motoo (Gifu JPX) Kato Ritsuko (Gifu JPX), Resin compositions and printed circuit boards using the same.
    상세보기

이 특허를 인용한 특허 (85)

  1. Haalck, Lutz; Gedig, Erk; Hoelpert, Hans-Juergen; Podsadlowski, Viola, 3-spiro-cyanin fluorochromes and their use in bioassays.
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  2. Narayanan, Narasimhachari, 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof.
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  4. Bell, Michael L.; Lin, Yuan; Michael, Josephine M.; Pentoney, Jr., Stephen L.; Tsay, Tsong-Tseh, Analyte detection system.
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  7. Shah, Shishir, Arrays, computer program products and methods for in silico array-based comparative binding assays.
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  8. Kupcho, Kevin R.; Vogel, Kurt; Werner, Elizabeth A.; Beebe, Jane A.; Klink, Tony A.; Lasky, David A.; Kleman Leyer, Karen M.; Somberg, Richard, Bimolecular optical probes.
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  9. Narayanan, Narasimhachari; Groves, Kevin; Peterson, Jeffrey D.; Rajopadhye, Milind, Biocompatible N, N-disubstituted sulfonamide-containing fluorescent dye labels.
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  10. David, Ayelet; Ashkenasy, Gonen; Shamay, Yosi, Caged cell penetrating peptide-polymer conjugates for diagnostic and therapeutic applications.
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  12. Minami, Masato; Tomida, Yoshinori; Takahashi, Atsushi; Kato, Kouichi; Tomatsu, Fumiko; Inoue, Sachiko, Compound, probe containing the novel compound, and fluorescence-imaging contrast agent containing the novel compound or the probe.
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  34. Bradford, Jolene; Cheung, Ching-Ying; Huang, Shih-Jung; Pinson, Patrick; Yue, Stephen, Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use.
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  44. Iwata,Yuji; Sakurada,Kazuaki, Liquid crystal display device manufacturing method, liquid crystal display device manufactured with the liquid crystal display device manufacturing method, and liquid-crystal-display-device-mounted electronic device.
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  45. Dallwig, Jason Alfred; Hagen, David Carl; Cheung, Ching-Ying; Thomas, Gerald Alan; Yue, Stephen, Methine-substituted cyanine dye compounds.
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  52. Volkov, Andrei; Colbert, Costa M.; Pan, Ivan; Kraltcheva, Anelia; Reddy, Mitsu; Battulga, Nasanshargal; Rea, Michael A.; Lee, Keun Woo; Hardin, Susan H.; Mulder, Brent; Hebel, Chris; Bandekar, Alok, Method for analyzing dynamic detectable events at the single molecule level.
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