초록

Photodynamic therapy to prevent secondary cataracts is effected using photosensitizers such as green porphyrins as photoactive agents to destroy remnant lens epithelial cells.

대표청구항 ▼

[ We claim:] [1.] A method to prevent or inhibit the development of secondary cataract in the eye of a subject following removal of the lens during cataract surgery, which method comprises:administering to the lens capsule of a subject an amount of a green porphyrin sufficient to permit an effective

[ We claim:] [1.] A method to prevent or inhibit the development of secondary cataract in the eye of a subject following removal of the lens during cataract surgery, which method comprises:administering to the lens capsule of a subject an amount of a green porphyrin sufficient to permit an effective amount to localize in lens epithelial cells that remain following said surgery;permitting a sufficient time to elapse to allow said effective amount of green porphyrin to localize in said lens epithelial cells; andirradiating said lens epithelial cells with light that is absorbed by the green porphyrin at an energy level sufficient to destroy substantially all of said lens epithelial cells.