초록 ▼

The present invention relates to bioassay materials useful for the detection of toxic substances and, more particularly, to packaging materials for food and other products, along with methods for their manufacture and use. The invention provides a unique composite material capable of detecting and i

The present invention relates to bioassay materials useful for the detection of toxic substances and, more particularly, to packaging materials for food and other products, along with methods for their manufacture and use. The invention provides a unique composite material capable of detecting and identifying multiple biological materials within a single package. The biological material identification system is designed for incorporation into existing types of flexible packaging material such as polyolefin films, and its introduction into the existing packaging infrastructure will require little or no change to present systems or procedures.

대표청구항 ▼

[ I claim:] [1.] A biological assay material for detecting the presence of a particular toxic substance comprising:a base layer which is a flexible polyoletin film having a surface which has undergone a treatment step effective to enhance said film's ability to immobilize a ligand applied thereto;a

[ I claim:] [1.] A biological assay material for detecting the presence of a particular toxic substance comprising:a base layer which is a flexible polyoletin film having a surface which has undergone a treatment step effective to enhance said film's ability to immobilize a ligand applied thereto;a capture antibody which is a biologically active ligand characterized by its ability to recognize an epitope of the particular toxic substance, said ligand being immobilized onto said surface of said polyolefin film;a first agarose gelcoat layer overlying the capture antibody, said agarose layer being permeable to the toxic substance and containing ingredients to enhance the growth thereof, said layer further containing a detector antibody which is a biologically active ligand characterized by its ability to recognize a different epitope of said particular toxic substance, thereby forming a detector antibody/antigen complex; anda second protective gelcoat layer overlying the detector antibody and having a degree of porosity whereby passage of said toxic substance is permitted and passage of said detector antibody/antigen complex is prevented, said second protective gelcoat layer having a degree of abrasion resistance effective to protect the biological assay material.