초록 ▼

An apparatus and method for sealing a plurality of columns containing media for use in liquid chromatography. The invention involves two sealing assemblies, each having a plurality of sealing heads. The sealing heads are sized to receive ends of the columns and to seal the columns when the heads are

An apparatus and method for sealing a plurality of columns containing media for use in liquid chromatography. The invention involves two sealing assemblies, each having a plurality of sealing heads. The sealing heads are sized to receive ends of the columns and to seal the columns when the heads are compressed. Compressive force is exerted by or through springs to permit the sealing heads to adapt to the length of the media bed within each column. The apparatus may include a pressure containment vessel for subjecting the columns to radial compression.

대표청구항 ▼

[ What is claimed is:] [31.] The combination comprising:a plurality of chromatography columns, each of said columns containing media and having two ends;an upper sealing assembly, including a plurality of upper sealing heads, each of said upper sealing heads being sized to receive an upper end of on

[ What is claimed is:] [31.] The combination comprising:a plurality of chromatography columns, each of said columns containing media and having two ends;an upper sealing assembly, including a plurality of upper sealing heads, each of said upper sealing heads being sized to receive an upper end of one of said chromatography columns, each of said upper sealing heads being capable of creating a seal with one of said chromatography columns; anda lower sealing assembly, connectable to and alignable with said upper sealing assembly, said lower sealing assembly having a plurality of lower sealing heads aligned with respective said upper sealing heads, each of said lower sealing heads being sized to receive a lower end of one of said chromatography columns, each of said lower sealing heads being capable of creating a seal with one of said chromatography columns.