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Methods and apparatus for fine particle formation 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61M-011/00
출원번호 US-0847310 (1997-04-24)
발명자 / 주소
  • Sievers Robert E.
  • Karst Uwe,DEX
출원인 / 주소
  • The Board of Regents of the University of Co
대리인 / 주소
    Greenlee, Winner and Sullivan, P.C.
인용정보 피인용 횟수 : 170  인용 특허 : 30

초록

Methods and apparatuses are provided for forming fine particles of a desired substance comprising dissolving said substance in a fluid such as water to form a solution and mixing the solution with a second fluid such as supercritical carbon dioxide which becomes a gas upon rapid pressure release, an

대표청구항

[ What is claimed is:] [1.] A device for making fine particles of a substance having an average diameter of less than about 6.5 .mu.m comprising:(a) a first pressurized chamber containing a first nongaseous supercritical or near critical fluid;(b) a second chamber containing a solution or suspension

이 특허에 인용된 특허 (30)

  1. Sioutas Constantinos (St. Paul MN), Aerosol actuator providing increased respirable fraction.
  2. Stern ; David, Aerosol dispensed latex paint and package containing the same.
  3. Sievers Robert E. (Boulder CO) Hansen Brian N. (Boulder CO), Chemical deposition methods using supercritical fluid solutions.
  4. Yamanis Jean (Morristown NJ), Continuous process for production of fine particulate ceramics.
  5. Ecanow Bernard (Wilmette IL), Drug delivery compositions and methods.
  6. Jinks Philip A. (Mountsorrel GB3) Bell Alexander (Chilwell GB3) Fischer Franz X. (Riehen CHX), Drug-containing chlorofluorocarbon aerosol propellent formulations.
  7. Schmitt William J., Finely divided solid crystalline powders via precipitation into an anti-solvent.
  8. Varaprath Padmakumari J. (Midland MI) Vincent Judith M. (Midland MI), Hair fixatives.
  9. Makiej ; Jr. Walter J. (70 Mount Hope St. Lowell MA 01859), Inhalation device utilizing two or more aerosol containers.
  10. Zoltan Bart J. (Old Tappan NJ) Laube Beth L. (Baltimore MD) Adams ; III George K. (Baltimore MD), Medication delivery system.
  11. Radhakrishnan Ramachandran (Fremont CA) Mihalko Paul J. (Fremont CA) Abra Robert M. (San Francisco CA), Method and apparatus for administering dehydrated liposomes by inhalation.
  12. Ronge Georg (Munich DEX), Method and apparatus for compressing, atomizing, and spraying liquid substances.
  13. McNab Donald W. (Long Beach CA), Method and apparatus for dispensing of volatile fluids.
  14. Fischer Wilfried (Burscheid DEX) Mller Bernd W. (Flintbek DEX), Method and apparatus for the manufacture of a product having a substance embedded in a carrier.
  15. Millington Arthur R. (Blackburn GB2), Method for producing a preparation for diagnostic radiology and apparatus therefor.
  16. Smith Richard D. (Richland WA), Method of making supercritical fluid molecular spray films, powder and fibers.
  17. Lindsay Alexander D. (East Brunswick NJ) Omilinsky Barry A. (Princeton Junction NJ), Method of preparing mixtures of active ingredients and excipients using liquid carbon dioxide.
  18. Sievers Robert E. (655 Northstar Ct. Boulder CO 80304) Hybertson Brooks M. (280 County Rd. 83 Boulder CO 80302) Hansen Brian N. (1510 Eisenhower Dr. Boulder CO 80302), Methods and apparatus for drug delivery using supercritical solutions.
  19. Sievers Robert E. (Boulder CO) Karst Uwe (Muenster DEX), Methods for fine particle formation.
  20. Ray Jon P. (12544 Judson Rd. San Antonio TX 78233) Turner James E. (307 Wayside San Antonio TX 78213) Ellis Michael P. (811 River Rd. San Antonio TX 78212) Oldham Ronald G. (1410 Tarton San Antonio T, Nicotine dispenser with polymeric reservoir of nicotine.
  21. Stopper, Howard R., Non-flammable aerosol propellant microemulsion system.
  22. Whitsett Jeffrey A. (Cincinnati OH), SAP-6-Val proteins and methods.
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  25. Kolleth Gary G. (Lakewood CO), Stable aqueous aerosol system with carbon dioxide propellant.
  26. Smith Richard D. (Richland WA), Supercritical fluid molecular spray film deposition and powder formation.
  27. Smith Richard D. (Richland WA), Supercritical fluid molecular spray thin films and fine powders.
  28. Fulton John L. (Richland WA) Smith Richard D. (Richland WA), Supercritical fluid reverse micelle separation.
  29. Lee Chinsoo (Charleston WV) Hoy Kenneth L. (St. Albans WV) Donohue Marc D. (Ellicot City MD), Supercritical fluids as diluents in liquid spray application of coatings.
  30. Martin James H. (8322 County Line Rd. Burr Ridge IL 60521), Unit dose dispenser.

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