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Polymeric microbeads and methods of preparation

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C08J-009/26
출원번호 US-0165520 (1998-10-02)
발명자 / 주소
  • Li Nai-Hong,CAX
  • Benson James R.
  • Kitagawa Naotaka
출원인 / 주소
  • Biopore Corporation
대리인 / 주소
    McCutchen, Doyle, Brown & Enersen, LLPMaher
인용정보 피인용 횟수 : 56  인용 특허 : 49

초록

The present invention relates to porous crosslinked polymeric microbeads having cavities joined by interconnecting pores wherein at least some of the cavities at the interior of each microbead communicate with the surface of the microbead. The present invention also relates to a process for producin

대표청구항

[ What is claimed is:] [1.] Porous crosslinked polymeric microbeads having cavities joined by interconnecting pores wherein: at least some of the cavities at the interior of each microbead communicate with the surface of the microbead; approximately 10% of the microbeads are substantially spherical

이 특허에 인용된 특허 (49)

  1. DesMarais Thomas A. (Norwood OH) Stone Keith J. (Fairfield OH) Thompson Hugh A. (Fairfield OH) Young Gerald A. (Cincinnati OH) LaVon Gary D. (Harrison OH) Dyer John C. (Cincinnati OH), Absorbent foam materials for aqueous body fluids and absorbent articles containing such materials.
  2. Jaisinghani Rajan A. (4200 Northwich Rd. Midlothian VA 23112), Apparatus and method for measuring the capillary pressure distribution of porous materials.
  3. Eury Robert P. (Half Moon Bay CA) Patel Rajesh (San Mateo CA), Blocked polymeric particles having internal pore networks for delivering active substances to selected environments.
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  5. Jankower Laura J. (Lafayette LA) Shipley Larry W. (Lafayette LA), Controlled release formulating employing resilient microbeads.
  6. Connick ; Jr. William J. (New Orleans LA), Controlled release of bioactive materials using alginate gel beads.
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  8. Dahlinder Lars-Erik D. (Mlndal SEX) Johansson Mats O. (Gteborg SEX) Sandberg John A. (Mlndal SEX) Sjgren John A. (Mlnlycke SEX), Drug preparation.
  9. Young Gerald A. (Cincinnati OH) LaVon Gary D. (Harrison OH) Taylor Gregory W. (Springdale OH), High efficiency absorbent articles for incontinence management.
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  14. Nacht Sergio ; Won Richard ; Katz Martin A. ; Cheng Tai ; Liau Christine J.Y. ; Eury Robert P. ; Froix Michael, Ionic beads useful for controlled release and adsorption.
  15. Barby Donald (Chester GB2) Haq Zia (Wirral GB2), Low density porous cross-linked polymeric materials and their preparation and use as carriers for included liquids.
  16. Adamski Robert P. (Missouri City TX) Mores Maryanne (Houston TX) Wong Pui K. (Houston TX) Davis Diana D. (Houston TX), Low density porous crosslinked polymeric materials.
  17. Edwards Christopher John C. (Buxtehude DEX) Gregory Donald P. (Wirral GB2) Sharples Martin (Wirral GB2), Low density porous elastic cross-linked polymeric materials and their preparation.
  18. Li Nai-Hong (Edmonton CAX) Mazid M. Abdul (Edmonton CAX), Macroporous particles as biocompatible chromatographic supports.
  19. Pouletty Philippe J. (Redwood City CA) Ingalz Thomas (San Jose CA), Matrix controlled method of delayed fluid delivery for assays.
  20. Won Richard (Palo Alto CA), Method for delivering an active ingredient by controlled time release utilizing a novel delivery vehicle which can be pr.
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  22. Li Nai-Hong,CAX ; Benson James R. ; Kitagawa Naotaka, Methods of preparing polymeric microbeds.
  23. Girot Pierre (Paris FRX) Boschetti Egisto (Croissy sur Seine FRX), Passivated and stabilized porous mineral oxide supports and method for the preparation and use of same.
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  25. Beresford Michael P. (36 Moody St. North Balwyn ; Victoria AUX 3104) Braun Willy (39 Glencairn Ave. Brighton ; Victoria AUX 3187), Polyester resin granules and process.
  26. Mathiowitz Edith (Brookline MA) Langer Robert S. (Somerville MA) Warshawsky Abraham (Rehovot MA ILX) Edelman Elazar (Brookline MA), Polymer composite for controlled release or membrane formation.
  27. Li Nai-Hong,CAX ; Benson James R. ; Kitagawa Naotaka, Polymeric microbeads.
  28. Li Nai-Hong (Edmonton CAX) Benson James R. (Los Gatos CA), Polymeric microbeads and method of preparation.
  29. Li Nai-Hong (Edmonton CAX) Benson James R. (Los Gatos CA) Kitagawa Naotaka (Fremont CA), Polymeric microbeads and method of preparation.
  30. Edwards Christopher J. C. (Buxtehude DEX) Hitchen David A. (Cheshire GB2) Sharples Martin (Wirral GB2), Porous carbon structures and methods for their preparation.
  31. Haq, Zia, Porous cross-linked absorbent polymeric materials.
  32. Elmes Alfred R. (Wirral GB2) Hammond Kevin (Wirral GB2) Sherrington David C. (Kirkintilloch GB6), Porous material and its preparation.
  33. DeLuca Patrick P. (Lexington KY) Kanke Motoko (Fukuyama JPX) Sato Toyomi (Tokyo CA JPX) Schroeder Hans G. (Encinitas CA), Porous microspheres for drug delivery and methods for making same.
  34. Katz Martin (Menlo Park CA) Cheng Chung-Heng (San Jose CA), Porous particles in preparations involving immiscible phases.
  35. Jomes Keith (Merseyside GB2) Lothian Barry R. (Merseyside GB2) Martin Alexander (Merseyside GB2) Taylor Graham (Merseyside GB2) Haq Zia (Merseyside GB2), Porous polymers.
  36. Jones Keith (Merseyside GB2) Lothian Barry R. (Merseyside GB2) Martin Alexander (Merseyside GB2) Taylor Graham (Merseyside GB2) Haq Zia (Merseyside GB2), Porous polymers.
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  38. Morishita Masataka (Shizuoka JA) Inaba Yoshihito (Shizuoka JA) Fukushima Mitsuru (Shizuoka JA) Kobari Sadami (Shizuoka JA) Nagata Akiho (Shizuoka JA) Abe Jinnosuke (Shizuoka JA), Preparation of microcapsules.
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  40. Fong, Jones W., Process for preparation of microspheres.
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  43. Brownscombe Thomas F. (Houston TX) Bass Ronald M. (Houston TX), Process for preparing low density porous crosslinked polymeric materials.
  44. Brownscombe Thomas F. (Houston TX) Gergen William P. (Houston TX) Bass Ronald M. (Houston TX) Mores Maryanne (Houston TX) Wong Pui K. (Houston TX), Process for preparing low density porous crosslinked polymeric materials.
  45. Sherrington David C. (Kirkintilloch GB6) Small Philip W. (Merseyside GBX), Substrate and process for making a substrate.
  46. Conte Ubaldo (Busto Arsizio ITX) La Manna Aldo (Pavia ITX) Colombo Paolo (Pavia ITX), Tablets with controlled-rate release of active substances.
  47. Won Richard (Palo Alto CA), Two step method for preparation of controlled release formulations.
  48. Bass Ronald M. (Houston TX) Brownscombe Thomas F. (Houston TX), Use of viscosity as an in-line diagnostic for high internal phase emulsion generation.
  49. Kershaw Robert William (Victoria AU) Lubbock Frederick John (Victoria AU) Polgar Livia (Victoria AU), Vesiculated polymer granules.

이 특허를 인용한 특허 (56)

  1. Song,Young Ho; Welch,Eric D.; Bluni,Scott T., Block copolymer particles.
  2. Bourne, George; Madden, Mike; Madenjian, Art; Rao, Doreen; Buiser, Marcia; Li, Jianmin; Rackley, Raymond; Gellman, Barry N., Bulking agent.
  3. Bourne, George; Madden, Michael; Madenjian, Arthur R.; Rao, Doreen; Buiser, Marcia; Li, Jianmin; Rackley, Raymon; Gellman, Barry N., Bulking agents.
  4. Buiser, Marcia S.; Keenan, Steve; Seehusen, Ashley; Nardone, Christopher, Coil assemblies, components and methods.
  5. Borodic, Gary, Composition for therapeutic and cosmetic botulinum toxin.
  6. Borodic,Gary, Composition for therapeutic and cosmetic botulinum toxin.
  7. Reb, Philippe, Compositions and methods using microspheres and non-ionic contrast agents.
  8. Reb, Philippe, Compositions and methods using microspheres and non-ionic contrast agents.
  9. Reb, Philippe, Compositions and methods using microspheres and non-ionic contrast agents.
  10. Richard, Robert E., Cross-linked polymer particles.
  11. Lanphere,Janel L.; McKenna,Erin P.; Naimark,Wendy; Buiser,Marcia S.; Mangin,Stephan P., Drug delivery particle.
  12. Buiser, Marcia S.; Seehusen, Ashley; Nardone, Christopher, Embolic coils.
  13. Elliott, Christopher J.; O'Connor, Patrick G., Embolic coils.
  14. Bell, Barbara; Casey, II, Thomas V.; Shaw, William J., Embolic compositions.
  15. Buiser, Marcia; Bellisario, Marc; Knapp, David; Mangin, Stephan; Lanphere, Janel, Embolization.
  16. DiCarlo, Paul; Casey, II, Thomas V.; Mangin, Stephan P., Embolization.
  17. Kamath, Kalpana; Freyman, Toby; Mishra, Shubhang, Embolization.
  18. Lanphere, Janel L.; Buiser, Marcia S.; Casey, Thomas V., Embolization.
  19. Lanphere,Janel; Buiser,Marcia; Casey, II,Thomas V., Embolization.
  20. Rioux, Robert F.; Casey, II, Thomas V.; Lanphere, Janel, Embolization.
  21. Rioux, Robert F.; Casey, II, Thomas V.; Lanphere, Janel L., Embolization.
  22. Borodic, Gary E., Extended length botulinum toxin formulation for human or mammalian use.
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  25. Tamori, Kouji; Abe, Takayoshi; Okano, Yusuke; Momiyama, Masaki; Kawai, Hiroshi; Hyugaji, Satoshi; Wang, Yong, Filler for affinity chromatography.
  26. Baldwin,Samuel P.; Skribiski,Robert P., Forming a chemically cross-linked particle of a desired shape and diameter.
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  30. Upadhyay, Rachana; Hall, Richard W. J., High porosity abrasive articles and methods of manufacturing same.
  31. Borodic, Gary E., High-potency botulinum toxin formulations.
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  35. Tan, Sharon Mi Lyn, Methods and systems for coating particles.
  36. Vogel, Jean-Marie; Boschetti, Egisto, Methods of using microspheres for active embolization.
  37. Vogel, Jean-Marie; Boschetti, Egisto, Microspheres for active embolization.
  38. Casey, II, Thomas V.; Damiano, Bud, Mixing and delivery of therapeutic compositions.
  39. Schwab, Justin J.; Raven, Joseph S.; Liu, Futian, Mucosal tissue adhesion via textured surface.
  40. Inoue, Hiroshi; Yamanaka, Koji, Organic porous material, process for manufacturing the same, and organic porous ion exchanger.
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  42. Anderson, Steven M.; Lanphere, Janel, Particles.
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  44. Borodic,Gary, Pharmaceuticaltoxin compositions.
  45. Cooper,Andrew Ian; Zhang,Haifei, Porous beads and method of production thereof.
  46. Lanphere, Janel; St. Pierre, Ernest J.; Kapoglis, Greg; Casey, II, Thomas V., Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient.
  47. Lanphere,Janel L.; Pierre,Ernest J.; Kapoglis,Greg; Casey, II,Thomas V., Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient.
  48. Buiser,Marcia; Baldwin,Samuel P., Processes for manufacturing polymeric microspheres.
  49. Ma, Guanghui; Su, Zhiguo; Zhou, Weiqing; Wei, Qiang, Super-macroporous polymeric microspheres and preparation method thereof.
  50. Bourne, George; Buiser, Marcia S.; Casey, II, Thomas V.; Keenan, Steve; Lanphere, Janel L.; Li, Jianmin; McKenna, Erin P.; Minasian, Zarouhi; Rao, Doreen, Tissue treatment.
  51. Bourne,George; Buiser,Marcia S.; Casey, II,Thomas V.; Keenan,Steve; Lanphere,Janel L.; Li,Jianmin; McKenna,Erin P.; Minasian,Zarouhi; Rao,Doreen, Tissue treatment.
  52. Lanphere, Janel L.; DiCarlo, Paul; Anderson, Steven M., Tissue-treatment methods.
  53. Lanphere, Janel L.; DiCarlo, Paul; Anderson, Steven M., Tissue-treatment methods.
  54. Nair, Mridula; Yang, Xiqiang; Jones, Tamara K.; Morgan, Jason, Toner porous particles containing hydrocolloids.
  55. Nair, Mridula; Yang, Xiqiang; Jones, Tamara K.; Morgan, Jason, Toner porous particles containing hydrocolloids.
  56. Borodic, Gary E., Topical ocular preparation of botulinum toxin for use in ocular surface disease.
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