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Automatic immunoassay method and apparatus 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-025/20
  • G01N-021/00
  • G01N-035/00
  • C12M-003/02
출원번호 US-0147206 (1998-10-28)
국제출원번호 PCT/JP96/01194 (1996-05-01)
§371/§102 date 19981028 (19981028)
국제공개번호 WO-9741437 (1997-11-06)
발명자 / 주소
  • Iwahashi Kyoichi,JPX
  • Kawamura Toshimi,JPX
  • Ikeda Eiji,JPX
  • Sato Mitsutoshi,JPX
출원인 / 주소
  • Sanko Junyaku Co., Ltd., JPX
대리인 / 주소
    Kintner
인용정보 피인용 횟수 : 52  인용 특허 : 22

초록

An automatic immunoassay method and apparatus which not only permit automatic operations of supplying and discarding reaction tubes, washing for B/F separation, dispensation of reagents, and measurement, but also permit the reaction time to be varied arbitrarily and can cope with any of the assay te

대표청구항

[ What is claimed is:] [1.] An automatic immunoassay apparatus comprising:a reaction tube turret that rotates intermittently at a predetermined speed;a reaction tube holding portion including a plurality of reaction tube holders arranged in two rows composed of an inner row and an outer row along th

이 특허에 인용된 특허 (22)

  1. Ootani Toshihiro (Kobe JPX) Izumi Takayoshi (Kobe JPX), Apparatus for aspirating and discharging a liquid sample.
  2. Wang Chi-Chin (Wilmington DE) McKeever Robert T. (Landenberg PA) Salyers Marshall L. (Malvern PA), Apparatus for automatically processing magnetic solid phase reagents.
  3. Schulte Harvey (Los Altos CA) Noto Sal (Sunnyvale CA), Apparatus for method for causing vortices in a test tube.
  4. Babson Arthur L. (Chester NJ) Ross Arthur F. (Mendham NJ) Olson Douglas R. (Doylestown PA) Giter Gershon (Highland Park MN) Huebner Victor R. (Newtown Square PA), Automated immunoassay analyzer with pictorial display of assay information.
  5. Ootani Toshihiro (Kobe JPX) Izumi Takayoshi (Kobe JPX), Automated immunochemical analyzer.
  6. Uzan Michel,FRX ; Gicquel Thierry,FRX, Automatic apparatus for immunological assay.
  7. Suzuki Yoshiyuki (Tokyo JPX) Kato Takahiko (Chigasaki JPX), Automatic cycling reaction apparatus and automatic analyzing apparatus using the same.
  8. Sato Takeshi (Katsuta JPX) Mimura Tomonori (Katsuta JPX), Automatic enzyme immunoassay analyzer.
  9. Wakatake Koichi (Tokyo JPX), Automatic immunity analysis apparatus with magnetic particle separation.
  10. Kawaguchi Seiji,JPX ; Kono Toshiaki,JPX ; Hayashi Hidechika,JPX, Device and method for automatic sample pretreatment.
  11. Choperena Alfredo ; Krogh Ross ; Prasad Venkatesh ; Giter Gershon, Device for automatic chemical analysis.
  12. Chandler Howard M. (Mississauga CAX), Device for performing qualitative enzyme immunoassays.
  13. Chandler Howard M. (Orton CAX), Device for performing qualitative enzyme immunoassays.
  14. Chandler Howard M. (Orton CAX), Device for performing quantitative chemical and immunochemical assays.
  15. Nakayama Naoki (Wako JPX) Akiyama Akio (Tokyo JPX) Ushida Takayuki (Tokyo JPX) Takao Hiroshi (Tokyo JPX), Dispensing apparatus.
  16. Uzan Michel,FRX ; Gicquel Thierry,FRX ; Lentwojt Edouard,FRX ; Marminio Dario,FRX, Immunodiagnostic reagent for carrying out a multi-stage immunoassay of at least one biological substance in a plurality.
  17. Grandone, Cass J., Locking rack and disposable sample cartridge.
  18. Axford Herbert G. (5 Masters Rd. Willowdale ; Ontario CAX) Jacob Jacob P. (R.R. #4 Tottenham ; Ontario CAX), Method and apparatus for bacteria testing.
  19. Laska Paul F. (510 Wyndham Rd. Wilmington DE 19809) Imai Kyoko (Ichige 622-23 Katsuta ; Ibaraki JPX) Hashimoto Hiroshi (Tokai 1616 Nakagun ; Ibaraki JPX) Betsui Hajime (Tahiko 1409-2 Katsuta ; Ibarak, Method and apparatus for effecting a plurality of assays on a plurality of samples in an automatic analytical device.
  20. Chandler Howard M. (Victoria AUX) Healey Kevin (Victoria AUX) Hurrell John G. R. (Victoria AUX), Method for detecting antigens and antibodies.
  21. Bajard Jean,FRX, Process for bacteria identification and for determination of the sensitivity of bacteria to antibiotics and apparatus.
  22. Aota Kensaku (Hyogo JPX) Ishikawa Kunio (Akashi JPX) Toyoda Jun (Kobe JPX) Tani Souichi (Kakogawa JPX), Sample container turning apparatus.

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  1. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated analyzer for performing a nucleic acid-based assay.
  2. Ochranek, Brian L.; Arnquist, David C.; Oonuma, Takehiko; Tahara, Hirotoshi; Sato, Naoto; Smith, Bradley P., Automated diagnostic analyzers having rear accessible track systems and related methods.
  3. Ochranek, Brian L.; Arnquist, David C.; Oonuma, Takehiko; Tahara, Hirotoshi; Sato, Naoto, Automated diagnostic analyzers having vertically arranged carousels and related methods.
  4. Ochranek, Brian L.; Arnquist, David C.; Oonuma, Takehiko; Tahara, Hirotoshi; Sato, Naoto, Automated diagnostic analyzers having vertically arranged carousels and related methods.
  5. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  6. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  7. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  8. Ammann,Kelly G.; Burns,Ralph E.; Hansberry,Ernest V.; Horner,Glenn A.; Jakub,Cheryl A.; Kling,John E.; Nieglos,Donald J.; Schneider,Robert E.; Smith,Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  9. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for isolating and amplifying a target nucleic acid sequence.
  10. Ammann,Kelly G.; Burns,Ralph E.; Hansberry,Ernest V.; Horner,Glenn A.; Jakub,Cheryl A.; Kling,John E.; Nieglos,Donald J.; Schneider,Robert E.; Smith,Robert J., Automated process for preparing and amplifying a target nucleic acid sequence.
  11. Miller,Kerry Lynn, Automated quality control protocols in a multi-analyzer system.
  12. Ammann,Kelly G.; Burns,Ralph E.; Hansberry,Ernest V.; Horner,Glenn A.; Jakub,Cheryl A.; Kling,John E.; Nieglos,Donald J.; Schneider,Robert E.; Smith,Robert J., Automated system for isolating and amplifying a target nucleic acid sequence.
  13. Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence; Knight, Byron J.; Heinz, Robert E.; Macioszek, Jerzy A.; Davis, Christopher B.; Scalese, Robert F., Continuous process for performing multiple nucleic acid amplification assays.
  14. Ammann,Kelly G.; Hansberry,Ernest V., Device for agitating the fluid contents of a container.
  15. Ochranek, Brian L.; Arnquist, David C., Diagnostic analyzers with pretreatment carousels and related methods.
  16. Joseph E. Kercso ; Steven A. Sundberg ; Jeffrey A. Wolk ; Andrew W. Toth ; Calvin Y. H. Chow ; J. Wallace Parce, High throughput microfluidic systems and methods.
  17. Kercso,Joseph E.; Sundberg,Steven A.; Wolk,Jeffrey A.; Toth,Andrew W.; Chow,Calvin Y. H.; Parce,J. Wallace, High throughput microfluidic systems and methods.
  18. Ammann,Kelly G.; Schneider,Robert E.; Smith,Robert J., Incubator for use in an automated diagnostic analyzer.
  19. Burns,Ralph E., Instrument for detecting light emitted by the contents of a reaction receptacle.
  20. Liao, Qinghua, Integrated processing mechanism for uniformly-mixing and filtering sample.
  21. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Method for agitating the contents of a reaction receptacle within a temperature-controlled environment.
  22. Ammann, Kelly G.; Hansberry, Ernest V., Method for agitating the fluid contents of a container.
  23. Ammann, Kelly G.; Hansberry, Ernest V., Method for agitating the fluid contents of a container.
  24. Macioszek, Jerzy A.; Davis, Christopher B.; Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Scalese, Robert F.; Heinz, Robert E., Method for continuous mode processing of the contents of multiple reaction receptacles in a real-time amplification assay.
  25. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  26. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  27. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  28. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  29. Light, II, James P.; Carrick, James M., Method for determining the amount of an analyte in a sample.
  30. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Method for incubating the contents of a receptacle.
  31. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Method for introducing a fluid into a reaction receptacle contained within a temperature-controlled environment.
  32. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for performing an assay with a nucleic acid present in a specimen.
  33. Macioszek, Jerzy A.; Davis, Christopher B.; Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Scalese, Robert F.; Heinz, Robert E., Method for performing multi-formatted assays.
  34. Light, II, James P., Method for reducing the presence of amplification inhibitors in a reaction receptacle.
  35. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for simultaneously performing multiple amplification reactions.
  36. Knight, Byron J.; Opalsky, David; Schroeter, Brian, Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure.
  37. Burns,Ralph E.; Hansberry,Ernest V., Multiple ring assembly for providing specimen to reaction receptacles within an automated analyzer.
  38. Gebrian,Peter Louis; Evers,Timothy Patrick, Random access reagent delivery system for use in an automatic clinical analyzer.
  39. Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Heinz, Robert E.; Macioszek, Jerzy A.; Davis, Christopher B.; Scalese, Robert F., Signal measuring system having a movable signal measuring device.
  40. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., System and method for incubating the contents of a reaction receptacle.
  41. Ammann, Kelly G.; Hansberry, Ernest V., System for agitating the fluid contents of a container.
  42. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., System for incubating the contents of a reaction receptacle.
  43. Knight, Byron J.; Li, Haitao, System for performing multi-formatted assays.
  44. Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Heinz, Robert E.; Macioszek, Jerzy A.; Davis, Christopher B.; Scalese, Robert F., System for performing multi-formatted assays.
  45. Knight, Byron J., System for processing contents of a receptacle to detect an optical signal emitted by the contents.
  46. Hayes, Matthew J.; Knight, Byron J.; Li, Haitao; Scalese, Robert F., Systems and methods for detecting multiple optical signals.
  47. Hayes, Matthew J.; Knight, Byron J.; Li, Haitao; Scalese, Robert F., Systems and methods for detecting multiple optical signals.
  48. Heinz, Robert E.; Newell, Dennis; Opalsky, David; Rhubottom, Jason, Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector.
  49. Heinz, Robert E.; Newell, Dennis; Opalsky, David; Rhubottom, Jason, Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector.
  50. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Temperature-controlled incubator having a receptacle mixing mechanism.
  51. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Temperature-controlled incubator having an arcuate closure panel.
  52. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Temperature-controlled incubator having rotatable door.
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