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Collagen-polymer matrices with differential biodegradability 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/00
  • A61F-002/01
  • A61F-013/00
출원번호 US-0199139 (1998-11-24)
발명자 / 주소
  • Sierra David H.
출원인 / 주소
  • Cohesion Technologies, Inc.
대리인 / 주소
    Morrison & Foerster
인용정보 피인용 횟수 : 130  인용 특허 : 36

초록 ▼

The current invention is a biomedical implant comprising a biomedical matrix material and a biodegradable porosifying agent. As the porosifying agent degrades in situ, an implant with an inter-connecting network is formed. The resultant mechanically stable implant allows for tissue and fluid influx

대표청구항 ▼

[ I claim:] [1.] A method for forming a fibrin matrix at a tissue site comprising the steps of:providing particulate crosslinked gelatin in dry, liquid or solid form;mixing an effective fibrin-forming amount of thrombin with the particulate crosslinked gelatin to form a mixture; andallowing the mixt

이 특허에 인용된 특허 (36)

  1. Mikos Antonios G. (Houston TX), Biodegradable bone templates.
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  2. Urist Marshall R. (Pacific Palisades CA), Biodegradable organic polymer delivery system for bone morphogenetic protein.
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  3. Urist Marshall R. (Pacific Palisade CA), Biodegradable porous ceramic delivery system for bone morphogenetic protein.
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  4. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable system for regenerating the periodontium.
    상세보기
  5. Gerhart Tobin N. (Brookline MA) Hayes Wilson C. (Lincoln MA), Bioerodable implant composition.
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  6. Mitra Gautam (Kensington CA), Blood coagulation promoting product.
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  7. Mallouk Robert S. (Chadds Ford PA) Mortimer ; Jr. William P. (New Castle DE), Bone growth matrix and process for making it.
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  8. Sanderson John E. (North Miami FL), Bone replacement and repair putty material from unsaturated polyester resin and vinyl pyrrolidone.
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  9. Sauer Barry W. (Central SC), Canine ear implant and method for supporting defective auricular cartilage.
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  10. Kranzler Thane L. (Flagstaff AZ) Sharber Norman J. (Flagstaff AZ), Carvable implant material.
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  11. Chu George H. (Sunnyvale CA) Ogawa Yasushi (Pacifica CA) McPherson John M. (Hopkinton MA) Ksander George (Redwood City CA) Pratt Bruce (Union City CA) Hendricks Diana (Brea CA) McMullin Hugh (San Bru, Collagen wound healing matrices and process for their production.
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  12. Ksander George (Redwood City CA) Ogawa Yasushi (Pacifica CA), Collagen wound healing matrices and process for their production.
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  13. Rhee Woonza (Palo Alto CA) McCullough Kimberly (Hayward CA), Collagen-polymer tubes for use in vascular surgery.
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  14. Dillon Mark E. (Watertown MA), Composite macrostructure of ceramic and organic biomaterials.
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  15. Landi Henry P. (Westchester NY), Composite material having absorbable and non-absorbable components for use with mammalian tissue.
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  16. Dorman Linneaus C. (Midland MI) Meyers Paul A. (Dublin CA), Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics.
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  17. Dorman Linneaus C. (Midland MI) Meyers Paul A. (Dublin CA), Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics.
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  18. Gottlieb Sheldon K. (8708 Wandering Trail Drive Potomac MD 20854), Compositions containing collagen and methods of use for repairing depressed cutaneous scars.
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  19. Rose Eric (Palisades NY) Dresdale Arthur (Plainfield NJ), Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma.
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  20. Homsy Charles A. (11526 Raintree Circle Houston TX 77024), Implantable structure.
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  21. Draenert Klaus (Ottobrunn DEX), Implantation materials and a process for the production thereof.
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  22. Herweck Steve A. (Nashua) Karwoski Theodore (Hollis) Martakos Paul (Pelham NH), Manually separable multi-lumen vascular graft.
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  23. Draenert Klaus (Ottobrunn DEX), Materials for implantation comprising a polyacrylate containing spherical tricalcium phosphate particles.
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  24. Wahlig Helmut (Darmstadt DEX) Dingeldein Elvira (Dreieich DEX) Braun Dietrich (Darmstadt DEX), Medicinally useful, shaped mass of collagen resorbable in the body.
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  25. Alterbaum Robert (101 West 15th St. New York NY 10011), Method and apparatus for use in preparation of fibrinogen from a patient\s blood.
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  26. Scantlebury Todd V. (315 Woodland Dr. Flagstaff AZ 86001) Ambruster Jeanne B. (631 Toho Trail Flagstaff AZ 86001) Motsinger Suzanne (2805 N. Oakmont Flagstaff AZ 86004) Davidson Daniel F. (3923 Parad, Methods and articles for treating periodontal disease and bone defects.
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  27. Scantlebury Todd V. (Flagstaff AZ) Ambruster Jeanne B. (Flagstaff AZ) Motsinger Suzanne (Flagstaff AZ) Davidson Daniel F. (Flagstaff AZ) Hardwick William R. (Flagstaff AZ) Campbell Stephen E. (Cave C, Methods and articles for treating periodontal disease and bone defects.
    상세보기
  28. Marx Gerard (New York NY), Methods for tissue embedding and tissue culturing.
    상세보기
  29. Mathiowitz Edith (Brookline MA) Langer Robert S. (Somerville MA) Warshawsky Abraham (Rehovot MA ILX) Edelman Elazar (Brookline MA), Polymer composite for controlled release or membrane formation.
    상세보기
  30. Schindler Anton (Durham NC), Porous bioabsorbable polyesters.
    상세보기
  31. Lafferty Michael (Leucadia CA) Kline Daniel (Carlsbad CA) Slemon Charles S. (Encinitas CA), Portable arthroscope with disposable probe.
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  32. Dorman Linneaus C. (Midland MI) Meyers Paul A. (Dublin CA), Process for the preparation of hard tissue prosthetics.
    상세보기
  33. Dillon Mark E. (Watertown MA), Process of producing a composite macrostructure of organic and inorganic materials.
    상세보기
  34. Sierra David H. (San Jose CA) Luck Edward E. (Menlo Park CA) Brown Dennis M. (Menlo Park CA), Surgical adhesive material.
    상세보기
  35. Walthall Bennie J. (El Sobrante CA) McHugh Yvonne E. (Berkeley CA) Voss Houston F. (Pleasanton CA), Transplantable artificial tissue.
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  36. Kingdon Henry S. (Pasadena CA) Griffith Michael J. (Walnut CA) Lawrence Joyce (Claremont CA) Lundblad Roger L. (Chapel Hill NC), Viral-safe purified human thrombin.
    상세보기

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