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Methods for suppressing the binding of detectable probes to non-target sequences in hybridization assays 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12O-001/68
  • C12P-019/34
  • C07H-021/02
  • C07H-021/04
출원번호 US-0963472 (1997-11-03)
발명자 / 주소
  • Coull James M.
  • Hyldig-Nielsen Jens J.
  • Godtfredsen Sven E.,DKX
  • Fiandaca Mark J.
  • Stefano Kyriaki
출원인 / 주소
  • Dako A/S, DKX
대리인 / 주소
    Gildea
인용정보 피인용 횟수 : 141  인용 특허 : 33

초록

This invention relates to methods, kits and compositions suitable for the improved detection, analysis and quantitation of nucleic acid target sequences using probe based hybridization assays. The invention is more specifically directed to methods, kits and compositions suitable for suppressing the

대표청구항

[ We claim:] [1.] A method for suppressing the binding of a detectable probe to a non-target sequence in an assay of a sample for a single stranded target sequence, the method comprising the steps of:a. contacting the sample with a set containing two or more probes under conditions suitable for the

이 특허에 인용된 특허 (33)

  1. Nycz Colleen Marie ; Nadeau James G. ; Scott Patricia Brinkley ; Shank Daryl Dee ; Spears Patricia Anne, Amplification and detection of mycobacterial DNA K nucleic acids.
  2. Hyldig-Nielsen Jens J. (Vanlse DKX) Pluzek Karl-Johan (Smoerum DKX), Antibody to PNA/nucleic acid complexes.
  3. Arnold ; Jr. Lyle J. (San Diego CA), Assay for polynucleotides employing oligonucleotides to eliminate undesireable cross reactions.
  4. Ecker David J. (Leucadia CA) Buchardt Ole (Vaerlose DKX) Egholm Michael (Fredriksberg DKX) Nielsen Peter E. (Hjortevanget 509 DK 2980 Koddedal DKX) Berg Rolf H. (Rungsted Kyst DKX) Mollegaard Niels E, Cleaving double-stranded DNA with peptide nucleic acids.
  5. Wallace R. Bruce, Competitive hybridization technique.
  6. Wallace R. Bruce (Pasadena CA), Competitive hybridization technique.
  7. Gray Joe W. ; Pinkel Daniel, Compositions for chromosome-specific staining.
  8. Koster Hubert (Concord MA), DNA sequencing by mass spectrometry.
  9. Wu Annie L. (Penfield NY), Detection of amplified nucleic acid using secondary capture oligonucleotides and test kit.
  10. Pinkel Daniel (Walnut Creek CA) Gray Joe (San Francisco CA), High density array fabrication and readout method for a fiber optic biosensor.
  11. Shuber Anthony P., High throughput screening method for sequences or genetic alterations in nucleic acids.
  12. Genna John L. (Monroeville PA) Moreland Jeffrey B. (Pittsburgh PA) Eckert C. Edward (Plum Boro PA) Miller Ronald E. (Murrysville PA), In-line sampling/alloying system and method.
  13. Wang Chang-Ning J. ; Wu Kai-Yuan, Kits for detecting a target nucleic acid with blocking oligonucleotides.
  14. Trost Jrgen (Grafenberg DEX) Schieber Eberhard (Backnang DEX), Magnetic ignition system.
  15. Coull James M. (Westford MA) Christensen Leif (Valby DKX), Method for degradation and sequencing of polymers which sequentially eliminate terminal residues.
  16. Kohne David E. (La Jolla CA), Method for detecting, identifying, and quantitating organisms and viruses.
  17. Kohne David E. (La Jolla CA), Method for detecting, identifying, and quantitating organisms and viruses.
  18. Kohne David E. (La Jolla CA), Method for detecting, the presence and amount of prokaryotic organisms using specific rRNA subsequences as probes.
  19. Kohne David E. (La Jolla CA), Method for detecting, the presense or amount of a taxonomic group of organisms using specific R-RNA subsequences as prob.
  20. Kohne David E. (364 Nautilus St. La Jolla CA 92037), Method for detection, identification and quantitation of non-viral organisms.
  21. Kohne David E. (La Jolla CA), Method for determining the effect of antimicrobial agents on growth using ribosomal nucleic acid subunit subsequence spe.
  22. Kohne David E., Method for determining the sensitivity of microorganisms to anti microbial agents using ribosomal nucleic acid hybridi.
  23. Demers Daniel B. (Broad Run VA), Method for enhancing amplification in the polymerase chain reaction employing peptide nucleic acid (PNA).
  24. Kohne David E. (La Jolla CA), Method for preparing rRNA for hybridization with a probe.
  25. Wu Linxian ; Coombs Jana ; Malmstrom Sharon L. ; Glass Michael J., Methods and kits using inosine-containing probes for discriminating variant nucleic acid sequences.
  26. Glass Michael J. ; Coombs Jana ; Malmstrom Sharon L. ; Wu Linxian, Methods for detection and discrimination of multiple analytes using fluorescent technology.
  27. Caskey Charles T. (Houston TX) Gibbs Richard A. L. (Houston TX), Mutation detection by competitive oligonucleotide priming.
  28. Carrico Robert J. (Elkhart IN), Nucleic acid hybridization assay employing detectable anti-hybrid antibodies.
  29. Hammond Philip W. (Tehachapi CA) Endozo Anthony A. (Temecula CA), Nucleic acid hybridization assay probes, helper probes and amplification oligonucleotides targeted to Mycoplasma pneu.
  30. Lobberding Antonius (Wuppertal DEX) Mielke Burkhard (Leverkusen DEX) Schwemler Christoph (Leichlingen DEX) Schwenner Eckhard (Wuppertal DEX) Stropp Udo (Haan DEX) Springer Wolfgang (Wuppertal DEX) Kr, Nucleic acid-binding oligomers possessing N-branching for therapy and diagnostics.
  31. Nielsen Peter E. (Hjortevanget 509 DK 2980 Kokkedal DKX) Buchardt Ole (Sondergardsvej 73 DK 3500 Vaerlose DKX) Egholm Michael (Johnstrup Alle 3 DK 1923 Frederiksberg DKX) Berg Rolf H. (Strandvaenget , Peptide nucleic acids.
  32. Buchardt ; deceased Ole,DKX ; Buchardt ; representative by Dorte,DKX ; Egholm Michael ; Nielsen Peter Eigil,DKX ; Berg Rolf Henrik,DKX, Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility.
  33. Coull James M. (Acton MA) Gildea Brian (Canton MA) Koester Hubert (Concord MA), Succinimidyl trityl compounds and a process for preparing same.

이 특허를 인용한 특허 (141)

  1. Müller, Martin; Johns, Charles W.; Eberhardt, Michael, Aliquotter system and workflow.
  2. Winther, Lars; Key, Marc; Buchanan, Kristopher S.; Favuzzi, John; Guggenheimer, Benno, Apparatus for automated processing biological samples.
  3. Winther, Lars; Key, Marc; Buchanan, Kristopher; Favuzzi, John; Guggenheimer, Benno, Apparatus for automated processing biological samples.
  4. Winther, Lars; Key, Marc; Buchanan, Kristopher; Favuzzi, John; Guggenheimer, Benno, Apparatus for automated processing biological samples.
  5. Wilson, Brian D.; Anderson, David L.; Davis, Matthew S.; Erickson, Matthew D.; Johnson, Alan N.; Maurer, Garrick A.; Rosen, Michael J.; Sauerburger, Mark F.; Schmidt, Daniel R.; Wiltsie, Joshua D., Assay cartridge with reaction well.
  6. Lorincz, Attila T.; Lazar, James G., Assessment of human papilloma virus-related disease.
  7. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated analyzer for performing a nucleic acid-based assay.
  8. Ochranek, Brian L.; Arnquist, David C.; Oonuma, Takehiko; Tahara, Hirotoshi; Sato, Naoto; Smith, Bradley P., Automated diagnostic analyzers having rear accessible track systems and related methods.
  9. Ochranek, Brian L.; Arnquist, David C.; Oonuma, Takehiko; Tahara, Hirotoshi; Sato, Naoto, Automated diagnostic analyzers having vertically arranged carousels and related methods.
  10. Ochranek, Brian L.; Arnquist, David C.; Oonuma, Takehiko; Tahara, Hirotoshi; Sato, Naoto, Automated diagnostic analyzers having vertically arranged carousels and related methods.
  11. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  12. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  13. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  14. Ammann,Kelly G.; Burns,Ralph E.; Hansberry,Ernest V.; Horner,Glenn A.; Jakub,Cheryl A.; Kling,John E.; Nieglos,Donald J.; Schneider,Robert E.; Smith,Robert J., Automated process for detecting the presence of a target nucleic acid in a sample.
  15. Schmidt, Gunter; Thompson, Andrew Hugin, Catalytically generated mass labels.
  16. Johns, Charles W.; Otts, Stephen, Centrifuge system and workflow.
  17. Johansen, Jack T., Compositions and methods for detecting target analytes.
  18. Shoemaker, Daniel D.; Scherer, Stewart; Friend, Stephen H., Compositions and methods for exon profiling.
  19. Liu, Shubing; Ramachandran, Suganthi, Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media.
  20. Coull, James M.; Gildea, Brian D.; Hyldig-Nielsen, Jens J., Compositions comprising a linked acceptor moiety.
  21. Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence; Knight, Byron J.; Heinz, Robert E.; Macioszek, Jerzy A.; Davis, Christopher B.; Scalese, Robert F., Continuous process for performing multiple nucleic acid amplification assays.
  22. Appella, Daniel H.; Micklitsch, Christopher, Cross-coupled peptide nucleic acids for detection of nucleic acids of pathogens.
  23. Cohenford, Menashi A.; Lentrichia, Brian, Detection and typing of human papillomavirus using PNA probes.
  24. Cohenford, Menashi A.; Lentrichia, Brian, Detection and typing of human papillomavirus using PNA probes.
  25. Gildea,Brian D.; Coull,James M.; Hyldig Nielsen,Jens J.; Fiandaca,Mark J., Detection of nucleic acid using linear beacons.
  26. Anthony, James; Lorincz, Attila; Troy, John; Tan, Yanglin, Detection of nucleic acids by target-specific hybrid capture method.
  27. Nazarenko, Irina; Lorincz, Attila; Eder, Paul; Lowe, Brian; Mallonee, Richard; Thai, Ha, Detection of nucleic acids by target-specific hybrid capture method.
  28. Nazarenko, Irina; Lorincz, Attila; Eder, Paul; Lowe, Brian; Mallonee, Richard; Thai, Ha, Detection of nucleic acids by target-specific hybrid capture method.
  29. Nazarenko, Irina; Lorincz, Attila; Eder, Paul; Lowe, Brian; Mallonee, Richard; Thai, Ha, Detection of nucleic acids by target-specific hybrid capture method.
  30. Anthony, James; Lorincz, Attila; Troy, John; Tan, Yanglin, Detection of nucleic acids by type specific hybrid capture method.
  31. Anthony, James; Lorincz, Attila; Williams, Inna; Troy, John; Tang, Yanlin, Detection of nucleic acids by type-specific hybrid capture method.
  32. Anthony, James; Lorincz, Attila; Williams, Inna; Troy, John; Tang, Yanlin, Detection of nucleic acids by type-specific hybrid capture method.
  33. Anthony,James; Lorincz,Attila; Troy,John; Tan,Yanglin, Detection of nucleic acids by type-specific hybrid capture method.
  34. Ochranek, Brian L.; Arnquist, David C., Diagnostic analyzers with pretreatment carousels and related methods.
  35. Key, Marc; Feingold, Gordon; Welcher, Rosanne, Enhanced scheduling sample processing system and methods of biological slide processing.
  36. Key, Marc; Feingold, Gordon; Welcher, Rosanne, Enhanced scheduling sample processing system and methods of biological slide processing.
  37. Key, Marc; Feingold, Gordon; Welcher, Rosanne, Enhanced scheduling sample processing system and methods of biological slide processing.
  38. Mallonee, Richard; Qiu, Peter, Fast results hybrid capture assay and associated strategically truncated probes.
  39. Eder, Paul; Payne, Eric; Nazarenko, Irina; Ramachandran, Suganthi; Virmani, Arvind; Bell, Laura, Fast results hybrid capture assay and system.
  40. Eder, Paul; Payne, Eric; Nazarenko, Irina; Ramachandran, Suganthi; Virmani, Arvind; Bell, Laura, Fast results hybrid capture assay and system.
  41. Eder, Paul; Payne, Eric; Nazarenko, Irina; Ramachandran, Suganthi; Virmani, Arvind; Bell, Laura, Fast results hybrid capture assay on an automated platform.
  42. Shoemaker, Daniel D.; Scherer, Stewart; Altschuler, Steven J.; Wu, Lani F.; Armour, Christopher D., Gene discovery using microarrays.
  43. Erikson, Glen H.; Daksis, Jasmine, Genomic assay.
  44. Efimov,Vladimir; Fernandez,Joseph; Archdeacon,Dorothy; Archdeacon,John; Chakhmakhcheva,Oksana; Buryakova,Alla; Choob,Mikhail; Hondorp,Kyle, Hydroxyproline/phosphono oligonucleotide analogues, methods of synthesis and methods of use.
  45. Gildea, Brian D.; Coull, James M.; Hyldig-Nielsen, Jens J., In-situ methods for analyzing target sequences using linear beacons.
  46. Ammann,Kelly G.; Schneider,Robert E.; Smith,Robert J., Incubator for use in an automated diagnostic analyzer.
  47. Feingold, Gordon; Key, Marc; Favuzzi, John; Welcher, Rosanne, Information notification sample processing system and methods of biological slide processing.
  48. Feingold, Gordon; Key, Marc; Favuzzi, John; Welcher, Rosanne, Information notification sample processing system and methods of biological slide processing.
  49. Feingold, Gordon; Key, Marc; Favuzzi, John; Welcher, Rosanne, Information notification sample processing system and methods of biological slide processing.
  50. Feingold, Gordon; Key, Marc; Welcher, Rosanne; Favuzzi, John, Information notification sample processing system and methods of biological slide processing.
  51. Feingold,Gordon; Key,Marc; Welcher,Rosanne; Favuzzi,John, Information notification sample processing system and methods of biological slide processing.
  52. Burns,Ralph E., Instrument for detecting light emitted by the contents of a reaction receptacle.
  53. Feingold, Gordon; Key, Marc, Isolated communication sample processing system and methods of biological slide processing.
  54. Friend,Stephen H.; Stoughton,Roland; Linsley,Peter S.; Burchard,Julja, Iterative probe design and detailed expression profiling with flexible in-situ synthesis arrays.
  55. Johns, Charles W.; Rizzotte, Samuel H., Magnetic damping for specimen transport system.
  56. Lowe, Brian; Fulbright, Anna K.; Nazarenko, Irina, Materials and methods for detection of HPV nucleic acids.
  57. Sweet, Doug; Key, Marc; Feingold, Gordon; Buchanan, Kristopher S.; Lathrop, Bob; Favuzzi, John, Method and apparatus for automatic staining of tissue samples.
  58. Sweet, Doug; Key, Marc; Feingold, Gordon; Buchanan, Kristopher; Lathrop, Bob; Favuzzi, John, Method and apparatus for automatic staining of tissue samples.
  59. Sweet, Doug; Key, Marc; Feingold, Gordon; Buchanan, Kristopher; Lathrop, Bob; Favuzzi, John, Method and apparatus for automatic staining of tissue samples.
  60. Favuzzi, John; Guggenheimer, Benno; Rau, Jeff; Key, Marc; Lathrop, Robert; Welcher, Rosanne, Method and system for pretreatment of tissue slides.
  61. Favuzzi, John; Guggenheimer, Benno; Rau, Jeff; Key, Marc; Lathrop, Robert; Welcher, Rosanne, Method and system for pretreatment of tissue slides.
  62. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Method for agitating the contents of a reaction receptacle within a temperature-controlled environment.
  63. Ammann, Kelly G.; Hansberry, Ernest V., Method for agitating the fluid contents of a container.
  64. Ammann, Kelly G.; Hansberry, Ernest V., Method for agitating the fluid contents of a container.
  65. Macioszek, Jerzy A.; Davis, Christopher B.; Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Scalese, Robert F.; Heinz, Robert E., Method for continuous mode processing of the contents of multiple reaction receptacles in a real-time amplification assay.
  66. Schuler, Martin; Breitenbuecher, Frank; Hoffarth, Sandra; Stergar, Sarah-Luise, Method for detecting gene modifications by means of asymmetrical PCR and blocking agents.
  67. Arts, Eric J.; LaLonde, Matthew, Method for detecting single nucleotide polymorphisms.
  68. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  69. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  70. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  71. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for detecting the presence of a nucleic acid in a sample.
  72. Light, II, James P.; Carrick, James M., Method for determining the amount of an analyte in a sample.
  73. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Method for incubating the contents of a receptacle.
  74. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Method for introducing a fluid into a reaction receptacle contained within a temperature-controlled environment.
  75. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for performing an assay with a nucleic acid present in a specimen.
  76. Macioszek, Jerzy A.; Davis, Christopher B.; Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Scalese, Robert F.; Heinz, Robert E., Method for performing multi-formatted assays.
  77. Light, II, James P., Method for reducing the presence of amplification inhibitors in a reaction receptacle.
  78. Ammann, Kelly G.; Burns, Ralph E.; Hansberry, Ernest V.; Horner, Glenn A.; Jakub, Cheryl A.; Kling, John E.; Nieglos, Donald J.; Schneider, Robert E.; Smith, Robert J., Method for simultaneously performing multiple amplification reactions.
  79. Nazarenko, Irina, Method of determining and confirming the presence of an HPV in a sample.
  80. Okamoto, Tadashi; Yamamoto, Nobuko; Suzuki, Tomohiro, Method of spotting probes on a solid support.
  81. James M. Coull ; Brian D. Gildea ; Jens J. Hyldig-Nielsen, Method, kits and compositions pertaining to detection complexes.
  82. Knight, Byron J.; Opalsky, David; Schroeter, Brian, Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure.
  83. O'Neil, Dominic; Nazarenko, Irina; Basham, Holly; Virmani, Arvind; Agarwal, Shiuli; Shukla, Mridula, Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids.
  84. Rothmann, Thomas; Nazarenko, Irina; O'Neil, Dominic; Virmani, Arvind; Lowe, Brian; Agarwal, Shiuli; Basham, Holly, Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids.
  85. Francois J.-M. Iris FR; Jean-Louis Pourny FR, Methods for detection of nucleic acid polymorphisms using peptide-labeled oligonucleotides and antibody arrays.
  86. Rigby, Susan; O'Keefe, Heather P.; Stender, Henrik, Methods for determining organisms not requiring the separation of fixative or excess probe.
  87. Burchard,Julja, Methods for determining the specificity and sensitivity of oligonucleo tides for hybridization.
  88. Jack T. Johansen ; Jens J. Hyldig-Nielsen ; Mark J. Fiandaca ; James M. Coull, Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices.
  89. Coull, James M.; Fiandaca, Mark J.; Kristjanson, Mark D.; Hyldig Nielsen, Jens J.; Creasey, Theresa S., Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation.
  90. Coull, James M.; Fiandaca, Mark J.; Kristjanson, Mark D.; Hyldig Nielsen, Jens J.; Creasey, Theresa S., Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation.
  91. Coull, James M.; Fiandaca, Mark J.; Kristjanson, Mark D.; Hyldig Nielsen, Jens J.; Creasey, Theresa S., Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation.
  92. Coull, James M.; Fiandaca, Mark J.; Kristjanson, Mark D.; Hyldig-Nielsen, Jens J.; Creasey, Theresa S., Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation.
  93. Coull, James M.; Fiandaca, Mark J.; Kristjanson, Mark D.; Hyldig-Nielsen, Jens J.; Creasey, Theresa S., Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation.
  94. Coull, James M.; Fiandaca, Mark J.; Kristjanson, Mark D.; Hyldig-Nielsen, Jens J.; Creasey, Theresa S., Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation.
  95. Coull, James M.; Fiandaca, Mark J.; Kristjanson, Mark D.; Hyldig-Nielsen, Jens J.; Creasey, Theresa S., Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation.
  96. Coull,James M.; Fiandaca,Mark J.; Kristjanson,Mark D.; Hyldig Nielsen,Jens J.; Creasey,Theresa S., Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation.
  97. Coull, James M.; Gildea, Brian D.; Hyldig-Nielsen, Jens J., Methods, kits and compositions pertaining to detection complexes.
  98. Brian D. Gildea ; James M. Coull ; Jens J. Hyldig-Nielsen ; Mark J. Fiandaca, Methods, kits and compositions pertaining to linear beacons.
  99. Gildea, Brian D.; Coull, James M.; Hyldig-Nielsen, Jens J.; Fiandaca, Mark J., Methods, kits and compositions pertaining to linear beacons.
  100. Leproust,Eric M.; Hirschberg,David L.; Delenstarr,Glenda C., Micro arrays with structured and unstructured probes.
  101. Lutz, Gordon J.; Tallent, Melanie K.; Lykens, Nicole Michele, Modulation of pre-MRNA using splice modulating oligonucleotides as therapeutic agents in the treatment of disease.
  102. Lutz, Gordon J.; Tallent, Melanie K.; Lykens, Nicole Michele, Modulation of pre-mRNA using splice modulating oligonucleotides as therapeutic agents in the treatment of disease.
  103. Lutz, Gordon J.; Tallent, Melanie K.; Lykens, Nicole Michele, Modulation of pre-mRNA using splice modulating oligonucleotides as therapeutic agents in the treatment of disease.
  104. Lutz, Gordon J.; Tallent, Melanie K.; Lykens, Nicole Michele, Modulation of pre-mRNA using splice modulating oligonucleotides as therapeutic agents in the treatment of disease.
  105. Nelson, Bryce P.; Strother, Todd C., Molecular interaction assays on a solid surface.
  106. Burns,Ralph E.; Hansberry,Ernest V., Multiple ring assembly for providing specimen to reaction receptacles within an automated analyzer.
  107. Lowe, Brian; Fulbright, Anna K.; Nazarenko, Irina, Non-target amplification method for detection of RNA splice-forms in a sample.
  108. Efimov, Vladimir; Fernandez, Joseph; Archdeacon, Dorothy; Archdeacon, John; Chakhmakhcheva, Oksana; Buryakova, Alla; Choob, Mikhail; Hondorp, Kyle, Oligonucleotide analogues, methods of synthesis and methods of use.
  109. Stender, Henrik; Hyldig-Nielsen, Jens J., PNA oligomers, oligomer sets, methods and kits pertaining to the detection of .
  110. Stender, Henrik, Peptide nucleic acid probes for detection, identification and/or quantitation of Pseudomonas (sensu stricto).
  111. Wiltsie, Joshua D., Pipettor including compliant coupling.
  112. Kuribayashi, Hideto; Fukui, Toshifumi; Yoshii, Hiroto, Probe, probe set, probe-immobilized carrier, and genetic testing method.
  113. Monte,Woodrow C., Probiotic/prebiotic composition and delivery method.
  114. Wilson, Brian D.; Davis, Matthew S.; Erickson, Matthew D.; Johnson, Alan N.; Maurer, Garrick A.; Schmidt, Daniel R.; Wiltsie, Joshua D., Reaction vessel.
  115. Wilson, Brian D.; Johnson, Alan N.; Kraihanzel, Charles S.; Wiltsie, Joshua D., Reagent cartridge.
  116. Baker, Tony, Removal of molecular assay interferences.
  117. Johns, Charles W.; Quint, Joseph F.; Chen, Chi S., Robotic arm.
  118. Müller, Martin; Weihs, Andreas; Gunzer, Gerhard; Eberhardt, Michael, Sample container cap with centrifugation status indicator device.
  119. Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Heinz, Robert E.; Macioszek, Jerzy A.; Davis, Christopher B.; Scalese, Robert F., Signal measuring system having a movable signal measuring device.
  120. Müller, Martin; Weihs, Andreas; Gunzer, Gerhard; Eberhardt, Michael, Specimen container detection.
  121. Wilson, Brian D.; Davis, Matthew S.; Johnson, Alan N.; Maurer, Garrick A., System and method for controlling thermal cycler modules.
  122. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., System and method for incubating the contents of a reaction receptacle.
  123. Johns, Charles W., System and method for processing samples.
  124. Gwynn, Robert B.; Wagner, Reed B., System and method including analytical units.
  125. Kraihanzel, Charles S., System and method including analytical units.
  126. Wilson, Brian D.; Anderson, David L.; Erickson, Matthew D.; Johnson, Alan N.; Rosen, Michael J.; Schmidt, Daniel R.; Wiltsie, Joshua D., System and method including analytical units.
  127. Wilson, Brian D.; Anderson, David L.; Davis, Matthew S.; Erickson, Matthew D.; Johnson, Alan N.; Maurer, Garrick A.; Rosen, Michael J.; Sauerburger, Mark F.; Schmidt, Daniel R.; Wiltsie, Joshua D., System and method including multiple processing lanes executing processing protocols.
  128. Wilson, Brian D.; Alaruri, Sami D.; Davis, Matthew S.; Erickson, Matthew D.; Johnson, Alan N.; Maurer, Garrick A.; Sauerburger, Mark F.; Schmidt, Daniel R.; Wiltsie, Joshua D.; Stachelek, Thomas M.; Yang, David L., System and method including thermal cycler modules.
  129. Ammann, Kelly G.; Hansberry, Ernest V., System for agitating the fluid contents of a container.
  130. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., System for incubating the contents of a reaction receptacle.
  131. Knight, Byron J.; Li, Haitao, System for performing multi-formatted assays.
  132. Lair, Gary D.; Nguyen, Thanh N.; Li, Haitao; Li, Florence F.; Knight, Byron J.; Heinz, Robert E.; Macioszek, Jerzy A.; Davis, Christopher B.; Scalese, Robert F., System for performing multi-formatted assays.
  133. Knight, Byron J., System for processing contents of a receptacle to detect an optical signal emitted by the contents.
  134. Hayes, Matthew J.; Knight, Byron J.; Li, Haitao; Scalese, Robert F., Systems and methods for detecting multiple optical signals.
  135. Hayes, Matthew J.; Knight, Byron J.; Li, Haitao; Scalese, Robert F., Systems and methods for detecting multiple optical signals.
  136. Heinz, Robert E.; Newell, Dennis; Opalsky, David; Rhubottom, Jason, Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector.
  137. Heinz, Robert E.; Newell, Dennis; Opalsky, David; Rhubottom, Jason, Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector.
  138. Buchanan, Kristopher; Key, Marc; Favuzzi, John; Welcher, Rosanne; Guggenheimer, Benno; Clark, Robert; Barber, Michael; Lathrop, Bob, Systems and methods of sample processing and temperature control.
  139. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Temperature-controlled incubator having a receptacle mixing mechanism.
  140. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Temperature-controlled incubator having an arcuate closure panel.
  141. Ammann, Kelly G.; Schneider, Robert E.; Smith, Robert J., Temperature-controlled incubator having rotatable door.

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