초록 ▼

An apparatus and method is provided for preparing and using a very large and diverse array of compounds on a substrate having rapidly accessible locations. The substrate contains cells in which the compounds of the array are located. Surrounding the cells is a non-wetable surface that prevents the s

An apparatus and method is provided for preparing and using a very large and diverse array of compounds on a substrate having rapidly accessible locations. The substrate contains cells in which the compounds of the array are located. Surrounding the cells is a non-wetable surface that prevents the solution in one cell from moving to adjacent cells. The compounds are delivered to the individual cells of the array by a micropipette attached to an X-Y translation stage.

대표청구항 ▼

[ What is claimed is:] [1.] A method for conducting a plurality of reactions on a substrate comprising at least one surface, said at least one surface comprising a plurality of cells at known locations, the location of each cell being encoded by information readable with an optical, electrical, magn

[ What is claimed is:] [1.] A method for conducting a plurality of reactions on a substrate comprising at least one surface, said at least one surface comprising a plurality of cells at known locations, the location of each cell being encoded by information readable with an optical, electrical, magnetic or electromagnetic sensor, said method comprising:(a) selecting a first set of one or more cells on said at least one surface of said substrate;(b) decoding the locations of said first set of one or more cells by said sensor and delivering a first reactant to each cell of said first set of one or more cells;(c) selecting a second set of one or more cells on said at least one surface of said substrate;(d) decoding the locations of said second set of one or more cells by said sensor and delivering a second reactant to each cell of said second set of one or more cells; and(e) reacting said first reactant in each cell of said first set of one or more cells and said second reactant in each cell of said second set of one or more cells such that covalent bonds are formed with said surface, wherein the first reactant is prevented from contacting the second set of one or more cells and the second reactant is prevented from contacting the first set of one or more cells.