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Fabrication of microchip drug delivery devices

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C25F-007/00
출원번호 US-0022322 (1998-02-11)
발명자 / 주소
  • Santini
  • Jr. John T.
  • Cima Michael J.
  • Langer Robert S.
출원인 / 주소
  • Massachusetts Institute of Technology
대리인 / 주소
    Arnall Golden & Gregory, LLP
인용정보 피인용 횟수 : 251  인용 특허 : 37

초록

Fabrication methods are provided for microchips that control both the rate and time of release of multiple chemical substances and allow for the release of a wide variety of molecules in either a continuous or pulsatile manner. In all of the preferred embodiments, a material that is impermeable to t

대표청구항

[ We claim:] [1.] A method of fabricating a microchip device for release of molecules having reservoirs containing the molecules for release comprising:providing a substrate;depositing and patterning a material on the substrate for use as an etch mask;etching a plurality of reservoirs in the substra

이 특허에 인용된 특허 (37)

  1. Stewart Russell J., Active microtubule-based separations by kinesins.
  2. Benjamin John D. (Malvern GB2) Mears Adrian L. (Cheltenham GB2) White John C. (Lincoln GB2), Active silicon implant devices.
  3. Ellinwood ; Jr. Everett H. (3519 Tonbridge Way Durham NC 27707), Apparatus and method for implanted self-powered medication dispensing.
  4. Parsi Edgardo J. (Lexington MA), Cell for electrically controlled transdermal drug delivery.
  5. Heil, Jr., Ronald W., Electrically controllable, non-occluding, body implantable drug delivery system.
  6. Miller Larry L. (Minneapolis MN) Blankespoor Ronald L. (Grand Rapids MI) Zinger Baruch (Rehovot ILX), Electrochemical controlled release drug delivery system.
  7. Wellinghoff Stephen T. (7718 Benbcook San Antonio TX 78250) Baker Charles K. (902 River Stone Dr. San Antonio TX 78258), Electrochemical drug release and article.
  8. Hanover Barry K. (Salt Lake City) Jacobsen Stephen C. (Salt Lake City) Simon Eric M. (Salt Lake City) Petelenz Tomasz (Salt Lake City) Mladejovsky Michael G. (Murray UT), Implantable drug delivery system with piston acutation.
  9. Portner Peer M. (Kensington CA) Jassawalla Jal S. (San Francisco CA), Implantable infusion device.
  10. Currie John F. (Montreal CAX) Ivanov Dentcho V. (Pierrefonds CAX) Lecours Andre (Longueuil CAX), Implantable medication dispensing device.
  11. Chien Yie W. (North Brunswick NJ) Kong-Jiann Li John (Plainsboro NJ) Liu Jue-Chen (East Brunswick NJ) Shi Wei-Min (Piscataway NJ) Siddiqui Ovais (Piscataway NJ) Sun Ying (King of Prussia PA), Iontotherapeutic device and process and iontotherapeutic unit dose.
  12. Kambara Koji (Tokyo JPX) Misawa Kazuo (Tokyo JPX) Honda Mikio (Tokyo JPX) Matsui Koichi (Tokyo JPX) Kohri Kitijiro (Tokyo JPX), Medical capsule device.
  13. Casper Robert A. (Raleigh NC) McCartney Michael L. (Durham NC) Jochem Warren J. (Cary NC) Parr Alan F. (Cary NC), Medical capsule device actuated by radio-frequency (RF) signal.
  14. Gross Joseph (Moshav Mazor ILX), Medication administering device.
  15. Keller Christopher G. (Albany CA), Method for fabrication of high vertical aspect ratio thin film structures.
  16. Ohman Ove,SEX ; Vieider Christian,SEX, Method for the manufacture of a membrane-containing microstructure.
  17. Whitesides George M. ; Xia Younan ; Wilbur James L. ; Jackman Rebecca J. ; Kim Enoch ; Prentiss Mara G. ; Mrksich Milan ; Kumar Amit ; Gorman Christopher B. ; Biebuyck Hans,CHX ; Berggren Karl K., Methods of etching articles via microcontact printing.
  18. Madou Marc J. (Palo Alto CA) Tierney Michael J. (San Jose CA), Micro-electrochemical valves and method.
  19. Wise Kensall D. ; Chen Jingkuang, Microchannel system for fluid delivery.
  20. Keller Christopher G. ; Ferrari Mauro, Microfabricated capsules for immunological isolation of cell transplants.
  21. Tu Jay Kuang-Jieh ; Ferrari Mauro, Microfabricated filter and capsule using a substrate sandwich.
  22. Chu Wen-Hwa ; Ferrari Mauro, Microfabricated filter with specially constructed channel walls, and containment well and capsule constructed with such.
  23. Keller Christopher G. (Albany CA) Ferrari Mauro (Walnut Creek CA), Microfabricated particle filter.
  24. Keller Christopher G. ; Ferrari Mauro, Microfabricated particle thin film filter and method of making it.
  25. Chu Wen-Hwa ; Ferrari Mauro, Micromachined capsules having porous membranes and bulk supports.
  26. Chu Wen-Hua ; Ferrari Mauro, Micromachined porous membranes with bulk support.
  27. Maurer Donald D. (Anoka MN) Williams Thomas J. (Oak Grove MN) Stevens Scott A. (Minneapolis MN), Multiple site drug iontophoresis electronic device and method.
  28. Jacobsen Stephen C. (Salt Lake City UT) Hanover Barry K. (Salt Lake City UT) Simon Eric M. (Salt Lake City UT) Petelenz Tomasz (Salt Lake City UT) Mladejovsky Michael G. (Murray UT), Multiple vesicle implantable drug delivery system.
  29. Bettinger David S. (8030 Coventry Grosse Ile MI 48138), Parenteral fluid medication reservoir pump.
  30. Cima Linda G. (Lexington MA) Cima Michael J. (Lexington MA), Preparation of medical devices by solid free-form fabrication methods.
  31. Fischell Robert E. (Silver Spring MD), Programmable control means for providing safe and controlled medication infusion.
  32. D\Angelo Joseph P. (Miami FL) Schur Henry (Miami FL), Selectable dosage transdermal delivery system.
  33. Ellinwood ; Jr. Everett H. (3519 Tonbridge Way Durham NC 27707), Self-powered implanted programmable medication system and method.
  34. Giampapa Vincent C. (89 Valley Rd. Montclair NJ 07042), Subcutaneous implantable multiple agent delivery system.
  35. Levy Robert J. (Ann Arbor MI) Sintov Amnon (Ann Arbor MI), System for controlled release of antiarrhythmic agents.
  36. Schentag Jerome J. (Eggertsville NY) D\Andrea David T. (Amherst NY), Telemetry capsule and process.
  37. Cima Linda G. (Lexington MA) Cima Michael J. (Lexington MA), Tissue regeneration matrices by solid free form fabrication techniques.

이 특허를 인용한 특허 (251)

  1. Zanzucchi, Peter J.; McBride, Sterling E.; Tsekoun, Alexei Guennadievich, Analyte concentration detection devices and methods.
  2. Zanzucchi, Peter J.; McBride, Sterling E.; Tsekoun, Alexei Guennadievich, Analyte concentration detection devices and methods.
  3. Emery, Jeffrey L.; Stivers, Carole R., Analyte detection devices and methods with hematocrit-volume correction and feedback control.
  4. Emery, Jeffrey L.; Stivers, Carole R., Analyte detection devices and methods with hematocrit/volume correction and feedback control.
  5. Emery, Jeffrey L.; Stivers, Carole R., Analyte detection devices and methods with hematocrit/volume correction and feedback control.
  6. Aceti, John Gregory; Loewy, Zvi Gerald; Moroney, III, Richard Morgan; Gregory, Christopher Carter; Zanzucchi, Peter John, Analyte monitor.
  7. Aceti, John Gregory; Loewy, Zvi Gerald; Moroney, III, Richard Morgan; Gregory, Christopher Carter; Zanzucchi, Peter John, Analyte monitor.
  8. Aceti, John Gregory; Lowey, Zvi Gerald; Moroney, Richard Morgan; Gregory, Christopher Carter; Zanzucchi, Peter John, Analyte monitor.
  9. Vitello,Christopher John; King,William F.; Ames,Eric L.; Ornellas,Frederic Adam, Apparatus and methods for administering bioactive compositions.
  10. Escutia, Raúl; Emery, Jeffrey L.; Litherland, Craig M., Arrangement for body fluid sample extraction.
  11. Stahmann, Jeffrey E.; Siejko, Krzysztof Z., Assessment of pulmonary vascular resistance via pulmonary artery pressure.
  12. Aceti, John Gregory; McBride, Sterling Eduard; Moroney, III, Richard Morgan; Gregory, Christopher Carter; Zanzucchi, Peter John, Autonomous, ambulatory analyte monitor or drug delivery device.
  13. Aceti, John Gregory; Mcbride, Sterling Eduard; Moroney, Richard Morgan; Gregory, Christopher Carter; Zanzucchi, Peter John, Autonomous, ambulatory analyte monitor or drug delivery device.
  14. Aceti,John Gregory; McBride,Sterling Eduard; Moroney, III,Richard Morgan; Gregory,Christopher Carter; Zanzucchi,Peter John, Autonomous, ambulatory analyte monitor or drug delivery device.
  15. Penner, Avi, Barometric pressure correction based on remote sources of information.
  16. Flanagan, Aiden, Bioabsorbable metal medical device and method of manufacture.
  17. Atanasoska, Liliana; Weber, Jan; Warner, Robert W., Bioerodible endoprostheses and methods of making the same.
  18. Atanasoska, Liliana; Weber, Jan; Warner, Robert W.; Grovender, Amy, Bioerodible endoprostheses and methods of making the same.
  19. Boismier, Dennis A.; Girton, Timothy S.; Larsen, Steven R.; Shedlov, Matt; Merdan, Ken; O'Brien, Barry, Bioerodible endoprostheses and methods of making the same.
  20. Weber, Jan, Bioerodible endoprostheses and methods of making the same.
  21. Radhakrishnan, Rajesh; Chandrasekaran, Chandru; Schewe, Scott R.; Merdan, Ken, Bioerodible endoprosthesis.
  22. Weber, Jan, Bioerodible endoprosthesis.
  23. Weber, Jan; Atanasoska, Liliana; Schewe, Scott, Bioerodible endoprosthesis with biostable inorganic layers.
  24. Stinson, Jonathan S., Bioerodible metallic ENDOPROSTHESES.
  25. Zhang, Yanan, Biosensor membrane composition, biosensor, and methods for making same.
  26. Escutia, Raul; Emery, Jeffrey L.; Litherland, Craig M., Body fluid sampling arrangements.
  27. Escutia, Raul; Emery, Jeffrey L.; Litherland, Craig M., Body fluid sampling arrangements.
  28. Escutia, Raúl; Litherland, Craig M.; Emery, Jeffrey L.; Jones, Jeffrey M.; Tomasco, Michael F.; Lipman, Kelley J., Body fluid sampling device—sampling site interface.
  29. Ganey, Timothy, Bone implants and method of manufacture.
  30. Lipman, Kelley J.; Tomasco, Michael F.; Ly, Peter Uy-Vu; Blomo, Jennifer Y.; Reynolds, Paul D.; Larkin, John F.; Gaffney, Robin S.; Tansey, Kimberly J.; Stewart, Christopher L.; Escutia, Raúl; Bowers, Robert W., Calibration material delivery devices and methods.
  31. Lipman, Kelley J.; Tomasco, Michael F.; Ly, Peter Uy-Vu; Chen, Jennifer Yuh-Jen; Reynolds, Paul D.; Larkin, John F.; Gaffney, Robin S.; Tansey, Kimberly J.; Stewart, Christopher L.; Escutia, Raúl; Bowers, Robert W., Calibration material delivery devices and methods.
  32. Gibbons, Ian; Wang, Chengwang; Roy, Shaunak; Holmes, Elizabeth A., Calibration of fluidic devices.
  33. Gibbons, Ian; Wang, Chengwang; Roy, Shaunak; Holmes, Elizabeth A., Calibration of fluidic devices.
  34. Escutia, Raul; Emery, Jeffrey L.; Litherland, Craig M., Catalysts for body fluid sample extraction.
  35. Kulessa,Sigmund, Catheter with block-overriding system.
  36. Foulger, Stephen H.; Jiang, Ping; Lattam, Amanda C.; Baughman, Travis; Ballato, John; Smith, Dennis W., Chemical compositions comprising crystalline colloidal arrays.
  37. Lee, Der-Yang; Sowden, Harry S.; Thomas, Martin, Composite dosage forms having an inlaid portion.
  38. Coppeta, Jonathan R.; Shelton, Kurt; Sheppard, Jr., Norman F.; Snell, Douglas; Santini, Catherine M. B., Compression and cold weld sealing method for an electrical via connection.
  39. Gazdzinski, Robert F., Computerized apparatus with ingestible probe.
  40. Gazdzinski, Robert F., Computerized information collection and processing apparatus.
  41. Gazdzinski, Robert F., Computerized information collection and processing apparatus.
  42. Gazdzinski, Robert F., Computerized information collection and processing apparatus and methods.
  43. Uhland, Scott A.; Polito, Benjamin F.; Maloney, John M.; Sheppard, Jr., Norman F.; Herman, Stephen J.; Yomtov, Barry M., Containment device with multi-layer reservoir cap structure.
  44. Prescott,James H.; Kreiger,Timothy; Proos,Elizabeth R., Control of drug release by transient modification of local microenvironments.
  45. Uhland,Scott A.; Polito,Benjamin F.; Maloney,John M.; Sheppard, Jr.,Norman F.; Herman,Stephen J.; Yomtov,Barry Y., Controlled release device and method using electrothermal ablation.
  46. Uhland,Scott A.; Polito,Benjamin F.; Maloney,John M.; Sheppard, Jr.,Norman F.; Herman,Stephen J.; Yomtov,Barry Y., Controlled release device and method using electrothermal ablation.
  47. Poirier, Christopher; Campbell, Anthony Stewart; Roberts, Carmichael S.; Rogers, John A.; Henderson, Winston E., Controlled transformation of non-transient electronics.
  48. Pickup, Ray L.; Lo, Clement C.; Noonan, William D., Cutaneous administration system.
  49. Pickup, Ray L.; Lo, Clement C.; Noonan, William D., Cutaneous administration system.
  50. Gibbons, Ian; Roy, Shaunak; Ku, Edmond, Detection and quantification of analytes in bodily fluids.
  51. Gibbons, Ian; Roy, Shaunak; Ku, Edmond, Detection and quantification of analytes in bodily fluids.
  52. Emery, Jeffrey L.; Tomasco, Michael F.; Hu, Charles, Detection meter and mode of operation.
  53. Santini, Jr., John T.; Cima, Michael J.; Uhland, Scott A., Device for controlling exposure of reservoir contents to surroundings.
  54. Santini, Jr.,John T.; Sheppard, Jr.,Norman F.; Young,Chung Chang; Langer,Robert S., Device for the controlled exposure of reservoir-based sensors.
  55. Kaelberer, Arnd; Baumann, Helmut; Scheuerer, Roland; Weber, Heribert, Device made of single-crystal silicon.
  56. Kaelberer, Arnd; Baumann, Helmut; Scheuerer, Roland; Weber, Heribert, Device made of single-crystal silicon.
  57. Reynolds, Paul D.; Escutia, Raul; Larkin, John F.; Hu, Charles; Tomasco, Michael F.; Bloom, Daniel R.; Vivolo, Joseph A.; Wiard, Richard M., Devices and methods for body fluid sampling and analysis.
  58. Escutia, Raul; Emery, Jeffrey Lorne, Devices and methods for facilitating fluid transport.
  59. Marga, Francoise Suzanne, Dried food products formed from cultured muscle cells.
  60. Lu, Shey-Shi; Yang, Yao-Joe; Huang, Yu-Jie; Lin, Chii-Wann; Liao, Hsin-Hung; Wang, Tao; Huang, Pen-Li; Wang, Yao-Hong, Drug delivery chip and fabricating method thereof.
  61. Shanley,John F.; Parker,Theodore L., Drug delivery device and method for bi-directional drug delivery.
  62. Kliman, Gilbert H., Drug delivery devices, kits and methods therefor.
  63. Madou, Marc J.; Daunert, Sylvia, Dual stage microvalve and method of use.
  64. Marga, Francoise Suzanne; Purcell, Brendan Patrick; Forgacs, Gabor; Forgacs, Andras, Edible and animal-product-free microcarriers for engineered meat.
  65. d'Alarcao, Marc; Calias, Pericles, Electrochemically degradable polymers.
  66. Gilad, Pinchas, Electronically-controlled device for release of drugs, proteins, and other organic or inorganic chemicals.
  67. Atanasoska, Liliana; Radhakrishnan, Rajesh; Arcand, Ben; Warner, Robert W., Endoprostheses.
  68. Weber, Jan, Endoprosthesis.
  69. Weber, Jan; Feng, James Q.; Atanasoska, Liliana, Endoprosthesis having a fiber meshwork disposed thereon.
  70. Weber, Jan; Atanasoska, Liliana, Endoprosthesis with three-dimensional disintegration control.
  71. Gazdzinski, Robert F., Endoscopic smart probe.
  72. Gazdzinski, Robert F., Endoscopic smart probe and method.
  73. Gazdzinski, Robert F., Endoscopic smart probe and method.
  74. Gazdzinski, Robert F., Endoscopic smart probe and method.
  75. Forgacs, Gabor; Marga, Francoise; Jakab, Karoly Robert, Engineered comestible meat.
  76. Shanley, John F., Expandable medical device for delivery of beneficial agent.
  77. Shanley, John F., Expandable medical device for delivery of beneficial agent.
  78. Shanley, John F., Expandable medical device for delivery of beneficial agent.
  79. Shanley, John F.; Eigler, Neal L.; Park, Kinam; Edelman, Elazer R., Expandable medical device for delivery of beneficial agent.
  80. Shanley, John F.; Eigler, Neal L.; Park, Kinam; Edelman, Elazer R., Expandable medical device for delivery of beneficial agent.
  81. Shanley,John F., Expandable medical device for delivery of beneficial agent.
  82. Shanley,John F., Expandable medical device for delivery of beneficial agent.
  83. Shanley,John F., Expandable medical device for delivery of beneficial agent.
  84. Shanley,John F.; Eigler,Neal L.; Park,Kinam; Edelman,Elazer R., Expandable medical device for delivery of beneficial agent.
  85. Shanley, John F., Expandable medical device with S-shaped bridging elements.
  86. Shanley, John F., Expandable medical device with beneficial agent concentration gradient.
  87. Shanley, John F., Expandable medical device with beneficial agent delivery mechanism.
  88. Shanley, John F., Expandable medical device with beneficial agent delivery mechanism.
  89. Shanley, John F., Expandable medical device with ductile hinges.
  90. Shanley, John F., Expandable medical device with ductile hinges.
  91. Shanley, John F.; Eigler, Neal L.; Edelman, Elazer R., Expandable medical device with improved spatial distribution.
  92. Shanley, John F.; Litvack, Frank; Parker, Theodore L.; Nguyen, Thai Minh, Expandable medical device with openings for delivery of multiple beneficial agents.
  93. Maloney,John M.; Sbiaa,Zouhair; Santini, Jr.,John T.; Sheppard, Jr.,Norman F.; Uhland,Scott A., Fabrication methods and structures for micro-reservoir devices.
  94. Santini, Jr., John T.; Cima, Michael J.; Langer, Robert S.; Ausiello, Dennis; Sheppard, Jr., Norman F.; Herman, Stephen J., Flexible microchip devices for ophthalmic and other applications.
  95. Doud, Darren; Campbell, Randolph E.; Erickson, Signe; MacFarlane, K. Angela; Barrett, Mike; Skieller, Christina; Batten, David; Stine, Greg; de Juan, Jr., Eugene; Sutton, Douglas; Farinas, Kathleen Cogan, Fluid exchange apparatus and methods.
  96. Kemp, Timothy M.; Todd, Chris; Oral, Ron; Zeng, Shulin; Howard, John; Fenton, Jeff, Fluidic medical devices and uses thereof.
  97. Kemp, Timothy Michael; Todd, Chris; Oral, Ron; Zeng, Shulin; Howard, John; Fenton, Jeff, Fluidic medical devices and uses thereof.
  98. Escutia, Raul; Litherland, Craig M.; Emery, Jeffrey L.; Pfeiffer, James W.; Pamichev, Christo P., Fully integrated wearable or handheld monitor.
  99. Uhland,Scott A.; Polito,Benjamin F.; Herman,Stephen J.; Santini, Jr.,John T.; Maloney,John M., Hermetically sealed microchip reservoir devices.
  100. Coppeta, Jonathan R.; Shelton, Kurt; Sheppard, Jr., Norman F.; Snell, Douglas; Santini, Catherine M. B., Hermetically sealing using a cold welded tongue and groove structure.
  101. Zeltser, Gregory; Piliavin, Michael, Implantable bioartificial perfusion system.
  102. Zeltser, Gregory; Piliavin, Michael, Implantable bioartificial perfusion system.
  103. Ausiello, Dennis; Santini, Jr., John T.; Herman, Stephen J.; Prescott, James H.; Uhland, Scott A.; Maloney, John M.; Polito, Benjamin F., Implantable device for controlled, extended delivery of parathyroid hormone.
  104. Tepper, Robert I.; Fuller, Jason; Jonas, Oliver; Santini, John, Implantable devices and methods for evaluation of active agents.
  105. Greenberg, Robert, Implantable drug delivery device.
  106. Greenberg,Robert, Implantable drug delivery device.
  107. Uhland,Scott A., Implantable drug delivery device.
  108. Adamis, Anthony P.; Miller, Joan W.; Gragoudas, Evangelos S.; Mescher, Mark J.; Dubé, Christopher E.; Borenstein, Jeffrey T.; Weinstein, Marcie G.; Miller, Raanan A.; Hansberry, Mitchell L., Implantable drug delivery device and use thereof.
  109. Santini, Jr., John T.; Hutchinson, Charles E., Implantable drug delivery stents.
  110. Santini, Jr., John T.; Sheppard, Jr., Norman F., Implantable medical device for diagnostic sensing.
  111. Farra, Robert, Implantable medical device for minimally-invasive insertion.
  112. Farra, Robert, Implantable medical device for minimally-invasive insertion.
  113. Shanley, John F.; Parker, Theodore L.; Park, Kinam, Implantable medical device with beneficial agent concentration gradient.
  114. Shanley,John F.; Parker,Theodore L., Implantable medical device with drug filled holes.
  115. Greenberg, Robert J.; Mech, Brian V., Implantable microfluidic delivery system using ultra-nanocrystalline diamond coating.
  116. de Juan, Jr., Eugene; Alster, Yair; Farinas, Kathleen Cogan; MacFarlane, K. Angela; Reich, Cary J.; Campbell, Randolph E., Implantable therapeutic device.
  117. de Juan, Jr., Eugene; Alster, Yair; Farinas, Kathleen Cogan; MacFarlane, K. Angela; Reich, Cary J.; Campbell, Randolph E., Implantable therapeutic device.
  118. de Juan, Jr., Eugene; Alster, Yair; Farinas, Kathleen Cogan; MacFarlane, K. Angela; Reich, Cary J.; Campbell, Randolph E., Implantable therapeutic device.
  119. Santini, Jr., John T.; Cima, Michael J.; Sheppard, Jr., Norman F.; Herman, Stephen J., Implantable, tissue conforming drug delivery device.
  120. Doron, Eyal; Rippin, Boaz, Implanted sensor system with optimized operational and sensing parameters.
  121. Gazdzinski, Robert F., Ingestible probe with agent delivery.
  122. Hyde, Roderick A.; Kindsvogel, Wayne R.; McKnight, Gary L.; Wood, Jr., Lowell L., Ingestible salt grabber.
  123. Chou, Kang-Jye; Guo, Hong; Ashton, Paul; Shimizu, Robert W.; Watson, David A., Injectable sustained release delivery devices.
  124. de Juan, Jr., Eugene; Alster, Yair; Farinas, Kathleen Cogan; MacFarlane, K. Angela; Reich, Cary J.; Campbell, Randolph E.; Doud, Darren; Erickson, Signe; Barrett, Mike; Batten, David; Skieller, Christina; Stine, Greg, Injector apparatus and method for drug delivery.
  125. de Juan, Jr., Eugene; Alster, Yair; Farinas, Kathleen Cogan; MacFarlane, K. Angela; Reich, Cary J.; Campbell, Randolph E.; Doud, Darren; Erickson, Signe; Barrett, Mike; Batten, David; Skieller, Christina; Stine, Greg, Injector apparatus and method for drug delivery.
  126. de Juan, Jr., Eugene; Erickson, Signe; Campbell, Randolph E.; Doud, Darren; Barrett, Michael; Batten, David; Skieller, Christina; Stine, Greg, Injector apparatus and method for drug delivery.
  127. Boland,Thomas; Wilson, Jr.,William Crisp; Xu,Tao, Ink-jet printing of viable cells.
  128. de Juan, Jr., Eugene; Campbell, Randolph E.; Erickson, Signe; Barrett, Mike; Skieller, Christina; Batten, David; Doud, Darren, Insertion and removal methods and apparatus for therapeutic devices.
  129. Martinson, James B.; Stark, John G.; Hanson, Timothy J. B.; Backes, Steven, Instrumented implantable stents, vascular grafts and other medical devices.
  130. Martinson, James B.; Stark, John G.; Hanson, Timothy J. B.; Backes, Steven J., Instrumented implantable stents, vascular grafts and other medical devices.
  131. Martinson, James B.; Stark, John G.; Hanson, Timothy J. B.; Backes, Steven, Instrumented orthopedic and other medical implants.
  132. Martinson, James B.; Stark, John G.; Hanson, Timothy J. B.; Backes, Steven J., Instrumented orthopedic and other medical implants.
  133. Holmes, Elizabeth A.; Gibbons, Ian; Young, Daniel L.; Michelson, Seth G., Integrated health data capture and analysis system.
  134. Holmes, Elizabeth A.; Gibbons, Ian; Young, Daniel L.; Michelson, Seth G., Integrated health data capture and analysis system.
  135. Metters, Andrew T.; Chollangi, Srinivas, Ligand-mediated controlled drug delivery.
  136. Coppeta,Jonathan R.; Uhland,Scott A.; Polito,Benjamin F.; Sheppard, Jr.,Norman F.; Feakes,Christina M.; Snell,Douglas B.; Santini, Jr.,John T., Low temperature methods for hermetically sealing reservoir devices.
  137. Santini, Jr.,John T.; Sheppard, Jr.,Norman F., Medical device and method for diagnostic sensing.
  138. Holmes, Elizabeth A., Medical device for analyte monitoring and drug delivery.
  139. Holmes, Elizabeth A., Medical device for analyte monitoring and drug delivery.
  140. Holmes, Elizabeth A.; Roy, Shaunak; Howard, John; Wang, Chengwang, Medical device for analyte monitoring and drug delivery.
  141. Holmes, Elizabeth A.; Roy, Shaunak; Howard, John; Wang, Chengwang, Medical device for analyte monitoring and drug delivery.
  142. Holmes,Elizabeth A.; Roy,Shaunak; Howard,John; Wang,Chengwang, Medical device for analyte monitoring and drug delivery.
  143. Yomtov, Barry M.; Herman, Stephen J.; Santini, Jr., John T., Medical device for neural stimulation and controlled drug delivery.
  144. Santini, Jr., John T.; Herman, Stephen J., Medical device for sensing glucose.
  145. Santini, Jr.,John T.; Cima,Michael J.; Langer,Robert S., Medical device with array of electrode-containing reservoirs.
  146. Santini, Jr., John T.; Sheppard, Jr., Norman F.; Young, Chung Chang; Langer, Robert S., Medical device with reservoir-based sensors.
  147. Girton, Timothy S., Medical devices and methods of making the same.
  148. Weber, Jan, Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides.
  149. Cho, Steven T.; Cromack, Keith; Jara-Almonte, James; VerLee, Don J, Medicine delivery system.
  150. Birdsall,Matthew J.; Klein,Richard L.; Maier,Nathan, Metallic composite coating for delivery of therapeutic agents from the surface of implantable devices.
  151. Gertner, Michael E.; Dadvand, Nazila; Klein, Richard L.; Maier, Nathan Christopher, Metallic structures incorporating bioactive materials and methods for creating the same.
  152. Diaz, Stephen Hunter; Park, Kinam, Method and apparatus for loading a beneficial agent into an expandable medical device.
  153. Diaz, Stephen Hunter; Park, Kinam, Method and apparatus for loading a beneficial agent into an expandable medical device.
  154. Diaz, Stephen Hunter; Park, Kinam; Shanley, John F., Method and apparatus for loading a beneficial agent into an expandable medical device.
  155. Shanley, John F.; Diaz, Stephen Hunter, Method and apparatus for loading a beneficial agent into an expandable medical device.
  156. Shanley, John F.; Diaz, Stephen Hunter, Method and apparatus for loading a beneficial agent into an expandable medical device.
  157. Penner, Avi; Gileadi, Eilezer, Method and device for electrochemical formation of therapeutic species in vivo.
  158. Penner, Avi; Gileadi, Eilezer, Method and device for electrochemical formation of therapeutic species in vivo.
  159. Ausiello,Dennis; Santini, Jr.,John T.; Herman,Stephen J.; Prescott,James H.; Uhland,Scott A.; Maloney,John M.; Polito,Benjamin F., Method and device for the controlled delivery of parathyroid hormone.
  160. Escutia, Raúl; Emery, Jeffrey L.; Litherland, Craig M., Method for body fluid sample extraction.
  161. Santini, Jr., John T.; Sheppard, Jr., Norman F.; Langer, Robert S.; Young, Chung Chang, Method for making reservoir-based sensor device.
  162. Santini, Jr., John T.; Sheppard, Jr., Norman F.; Langer, Robert S.; Young, Chung Chang, Method for operating a reservoir-based sensor device.
  163. Ashton, Paul, Method for treating and/or preventing retinal diseases with sustained release corticosteroids.
  164. Sheppard, Jr., Norman F.; Santini, Jr., John T.; Cima, Michael J.; Langer, Robert S.; Ausiello, Dennis, Method for wirelessly monitoring implanted medical device.
  165. Santini, Jr., John T.; Cima, Michael J.; Langer, Robert S.; Ausiello, Dennis; Sheppard, Jr., Norman F., Method of actuating implanted medical device.
  166. Santini, Jr., John T.; Cima, Michael J.; Langer, Robert S.; Göpferich, Achim, Method of controlled drug delivery from implant device.
  167. Greenberg, Robert J.; Mech, Brian V., Method of fabricating a microfluidic delivery system.
  168. Li, Shun-Por; Sowden, Harry S.; Wynn, David; Lee, Der-Yang; Thomas, Martin, Method of manufacturing modified release dosage forms.
  169. Santini, Jr., John T.; Cima, Michael J.; Langer, Robert S.; Ausiello, Dennis; Sheppard, Jr., Norman F., Method of opening reservoir of containment device.
  170. Shawgo, Rebecca S.; Sheppard, Jr., Norman F.; Cima, Michael J.; Santini, Jr., John T.; Herman, Stephen J.; Polito, Benjamin F.; Uhland, Scott A., Methods and devices for sealing microchip reservoir devices.
  171. Sheppard, Jr., Norman F.; Feakes, Christina M., Methods for conformal coating and sealing microchip reservoir devices.
  172. Uhland, Scott A.; Polito, Benjamin F.; Herman, Stephen J.; Santini, Jr., John T.; Maloney, John M., Methods for hermetically sealing microchip reservoir devices.
  173. Gibbons, Ian; Roy, Shaunak; Ku, Edmond, Methods for the detection of analytes in small-volume blood samples.
  174. Shuros, Allan C.; Li, Dan; Ni, Quan, Methods of monitoring hemodynamic status for rhythm discrimination within the heart.
  175. Gazdzinski, Robert F., Methods of processing data obtained from medical device.
  176. Gazdzinski, Robert F., Methods of processing data obtained from medical device.
  177. Coppeta, Jonathan R.; Santini, Jr., John T.; Uhland, Scott A., Micro-reservoir osmotic release systems and microtube array device.
  178. Richards, Amy C.; Santini, Jr., John T.; Cima, Michael J.; Langer, Robert S., Microchip devices for delivery of molecules and methods of fabrication thereof.
  179. Santini, Jr., John T.; Cima, Michael J.; Sheppard, Jr., Norman F.; Flynn, Nolan T.; Uhland, Scott A.; Sbiaa, Zouhair; Maloney, John M., Microchip devices with improved reservoir opening.
  180. Santini, Jr.,John T.; Cima,Michael J.; Langer,Robert S., Microchip drug delivery devices.
  181. Sheppard, Jr., Norman F.; Feakes, Christina M.; Santini, Jr., John T., Microchip reservoir devices and facilitated corrosion of electrodes.
  182. Sheppard, Jr.,Norman F.; Santini, Jr.,John T.; Herman,Stephen J.; Cima,Michael J.; Langer,Robert S.; Ausiello,Dennis, Microchip reservoir devices using wireless transmission of power and data.
  183. John T. Santini, Jr. ; Charles E. Hutchinson ; Scott A. Uhland ; Michael J. Cima ; Robert S. Langer ; Dennis Ausiello, Microfabricated devices for the delivery of molecules into a carrier fluid.
  184. Santini, Jr., John T.; Hutchinson, Charles E.; Uhland, Scott A.; Cima, Michael J.; Langer, Robert S.; Ausiello, Dennis, Microfabricated devices for the delivery of molecules into a carrier fluid.
  185. Santini, Jr., John T.; Sheppard, Jr., Norman F.; Young, Chung Chang; Langer, Robert S., Microfabricated devices for the storage and selective exposure of chemicals and devices.
  186. Santini, Jr., John T.; Sheppard, Jr., Norman F.; Young, Chung Chang; Langer, Robert S., Microfabricated devices for the storage and selective exposure of chemicals and devices.
  187. Johnson,Audrey M.; Cima,Michael J.; Langer,Robert S., Microscale lyophilization and drying methods for the stabilization of molecules.
  188. LaFollette, Rodney M.; Salmon, Linton G.; Harb, John N., Microscopic batteries for MEMS systems.
  189. LaFollette,Rodney M.; Salmon,Linton G.; Harb,John N., Microscopic batteries for MEMS systems.
  190. LaFollette,Rodney M.; Salmon,Linton G.; Harb,John N., Microscopic batteries integrated with MEMS systems.
  191. Sowden, Harry S., Modified release dosage form.
  192. Li, Shun-Por; Sowden, Harry S; Wynn, David; Lee, Der-Yang; Thomas, Martin, Modified release dosage forms.
  193. Sowden, Harry S.; Wynn, David; Li, Shun-Por; Lee, Der-Yang; Thomas, Martin, Modified release dosage forms.
  194. Santini, Jr., John T.; Sbiaa, Zouhair; Coppeta, Jonathan R.; Uhland, Scott A.; Sheppard, Jr., Norman F., Multi-cap reservoir devices for controlled release or exposure of reservoir contents.
  195. Santini, Jr., John T.; Sbiaa, Zouhair; Coppeta, Jonathan R.; Uhland, Scott A.; Sheppard, Jr., Norman F., Multi-opening reservoir devices for controlled release or exposure of reservoir contents.
  196. Santini, Jr., John T.; Staples, Mark A.; Herman, Stephen J., Multi-reservoir device for transdermal drug delivery and sensing.
  197. Litherland, Craig M.; Emery, Jeffrey L.; Escutia, Raul; Pfeiffer, James W.; Jones, Jeffrey M., Multi-site body fluid sampling and analysis cartridge.
  198. Bianchi, Keith; Hartsig, Bill; Nunn, Scott; Patel, Mukund; Sponsel, Mark; Vedrine, Lionel; Waitz, Ariel, Ocular implant delivery device and method.
  199. Erickson, Signe; Campbell, Randolph E.; Doud, Darren, Ophthalmic implant for delivering therapeutic substances.
  200. Holmes, Elizabeth A.; Roy, Shaunak; Howard, John; Wang, Chengwang; Gibbons, Ian; Kemp, Timothy M.; Qi, Shize Daniel, Point-of-care fluidic systems and uses thereof.
  201. Holmes, Elizabeth A.; Roy, Shaunak; Howard, John; Wang, Chengwang; Gibbons, Ian; Kemp, Timothy M.; Qi, Shize Daniel, Point-of-care fluidic systems and uses thereof.
  202. Reich, Cary J.; Barrett, Michael; Campbell, Randolph E.; Farinas, Kathleen C., Posterior segment drug delivery.
  203. Reich, Cary J.; Barrett, Michael; Campbell, Randolph E.; Farinas, Kathleen C., Posterior segment drug delivery.
  204. de Juan, Jr., Eugene; Alster, Yair; Chamow, Steven M.; Farinas, Kathleen Cogan; Giffor, III, Hanson S.; MacFarlane, K. Angela; Reich, Cary J.; Barrett, Michael; Campbell, Randolph E.; George, Robert; Sutton, Douglas, Posterior segment drug delivery.
  205. de Juan, Jr., Eugene; Alster, Yair; Chamow, Steven M.; Farinas, Kathleen Cogan; Gifford, III, Hanson S.; Macfarlane, K. Angela; Reich, Cary J.; Barrett, Michael; Campbell, Randolph E.; George, Robert; Sutton, Douglas, Posterior segment drug delivery.
  206. de Juan, Jr., Eugene; Alster, Yair; Farinas, Kathleen Cogan; Gifford, III, Hanson S.; MacFarlane, K. Angela; Reich, Cary J.; Barrett, Michael; Campbell, Randolph E.; Sutton, Douglas, Posterior segment drug delivery.
  207. de Juan, Jr., Eugene; Alster, Yair; Farinas, Kathleen Cogan; Gifford, III, Hanson S.; MacFarlane, K. Angela; Reich, Cary J.; Barrett, Michael; Campbell, Randolph E.; Sutton, Douglas, Posterior segment drug delivery.
  208. de Juan, Jr., Eugene; Alster, Yair; Gifford, III, Hanson S.; Barrett, Michael; Campbell, Randolph E.; Sutton, Douglas, Posterior segment drug delivery.
  209. Contadini, Carl D.; Skeath, Perry, Precision release aerosol device.
  210. Holmes, Elizabeth A.; Gibbons, Ian, Real-time detection of influenza virus.
  211. Holmes, Elizabeth A.; Gibbons, Ian, Real-time detection of influenza virus.
  212. Holmes, Elizabeth A.; Gibbons, Ian, Real-time detection of influenza virus.
  213. Stark, John G.; Oyen, Duane P. M.; Bybee, Thomas; Lohmann, Arthur M.; Boyd, Joel L., Remote monitoring of a patient.
  214. Stark, John G.; Oyen, Duane P.; Bybee, Thomas; Lohmann, Arthur M.; Boyd, Joel L., Remote monitoring of a patient.
  215. Stark, John G.; Oyen, Duane; Mowery, Blair P., Remote psychological evaluation.
  216. Varner, Signe Erickson; De Juan, Eugene; Barnes, Aaron Christopher; Shelley, Terry Harrison; Cooney, Michael J., Reservoir device for intraocular drug delivery.
  217. Varner, Signe Erickson; Dejuan, Eugene; Barnes, Aaron Christopher; Shelley, Terry Harrison; Cooney, Michael J., Reservoir device for intraocular drug delivery.
  218. Varner, Signe Erickson; de Juan, Jr., Eugene; Barnes, Aaron Christopher; Shelley, Terry Harrison; Cooney, Michael J., Reservoir device for intraocular drug delivery.
  219. Atanasoska, Liliana; Shippy, III, James Lee; Holman, Tom; Arney, Michael S.; Schoenle, Victor; Genovese, Frank; Feng, James Q.; Flanagan, Aiden; Weber, Jan, Self-buffering medical implants.
  220. De Juan, Jr., Eugene; Alster, Yair; Farinas, Kathleen Cogan; MacFarlane, K. Angela; Reich, Cary J.; Campbell, Randolph E.; Erickson, Signe, Small molecule delivery with implantable therapeutic device.
  221. Dong, Lijun; Zhao, Chao, Solid hole array and method for forming the same.
  222. Horvath, Judit; Astafieva, Irina; Erickson, Signe; Farinas, Kathleen Cogan, Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof.
  223. Horvath, Judit; Astafieva, Irina; Erickson, Signe; Farinas, Kathleen Cogan, Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof.
  224. Santini, Jr.,John T.; Hutchinson,Charles E., Stent for controlled release of drug.
  225. Shanley,John F., Stent wall structure.
  226. Shanley,John F., Stent wall structure.
  227. Scheuermann, Torsten; Weber, Jan; Deng, Charles; Stinson, Jonathan S.; Larsen, Steven R.; Boismier, Dennis A.; Edick, Jacob D., Surface treated bioerodible metal endoprostheses.
  228. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
  229. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
  230. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
  231. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
  232. Vitello, Christopher John; Welkley, Stephen R.; Evans, Andrew L; Greeven, John C., System and methods for administering bioactive compositions.
  233. Holmes, Elizabeth A.; Gibbons, Ian; Kemp, Timothy M.; Howard, John; Roy, Shaunak, Systems and methods for conducting animal studies.
  234. Tran, Binh C.; Mi, Bin; Harguth, Robert S., Systems and methods for controlling wireless signal transfers between ultrasound-enabled medical devices.
  235. Von Arx, Jeffrey A.; Mazar, Scott T.; Chavan, Abhi, Systems and methods for deriving relative physiologic measurements.
  236. Von Arx, Jeffrey A.; Mazar, Scott T.; Chavan, Abhi, Systems and methods for deriving relative physiologic measurements using a backend computing system.
  237. Doron, Eyal, Systems and methods for determining cardiac output using pulmonary artery pressure measurements.
  238. Holmes, Elizabeth A.; Gibbons, Ian; Howard, John; Roy, Shaunak; Wang, Chengwang; Kemp, Timothy M., Systems and methods for improving medical treatments.
  239. Roy, Shaunak; Takahashi, Malissa; Gibbons, Ian; Ku, Edmond; Dang, Thanh; Burd, Tammy; Vollmer, Adam; Holmes, Elizabeth A., Systems and methods of fluidic sample processing.
  240. Roy, Shaunak; Takahashi, Malissa; Gibbons, Ian; Ku, Edmond; Dang, Thanh; Burd, Tammy; Vollmer, Adam; Holmes, Elizabeth A., Systems and methods of fluidic sample processing.
  241. Roy, Shaunak; Takahashi, Melissa; Gibbons, Ian; Ku, Edmond; Dang, Thanh; Burd, Tammy; Vollmer, Adam; Holmes, Elizabeth A., Systems and methods of fluidic sample processing.
  242. Holmes, Elizabeth A.; Roy, Shaunak; Gibbons, Ian; Qi, Shize Daniel; Ku, Edmond; Todd, Chris; Takahashi, Melissa; Johnson, Bruce; Fenton, Jeff; Moravick, Keith; Springborn, Uwe; Delacruz, Anthony, Systems and methods of sample processing and fluid control in a fluidic system.
  243. Holmes, Elizabeth A.; Roy, Shaunak; Gibbons, Ian; Qi, Shize Daniel; Ku, Edmond; Todd, Chris; Takahashi, Melissa; Johnson, Bruce; Fenton, Jeff; Moravick, Keith; Springborn, Uwe; Delacruz, Anthony, Systems and methods of sample processing and fluid control in a fluidic system.
  244. Astafieva, Irina; Horvath, Judit; Farinas, Kathleen Cogan; Bueche, Blaine; Erickson, Signe, Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant.
  245. Shanley, John F.; Parker, Theodore L., Therapeutic agent delivery device with controlled therapeutic agent release rates.
  246. Shanley,John F.; Parker,Theodore L., Therapeutic agent delivery device with controlled therapeutic agent release rates.
  247. Santini, Jr., John T.; Cima, Michael J.; Uhland, Scott Albert, Thermally-activated microchip chemical delivery devices.
  248. Santini, Jr., John T.; Cima, Michael J.; Uhland, Scott Albert, Thermally-activated microchip chemical delivery devices.
  249. Santini, Jr.,John T.; Cima,Michael J.; Uhland,Scott Albert, Thermally-activated reservoir devices.
  250. Greenberg, Robert; Humayan, Mark, Transretinal implant and method of manufacture.
  251. Salo, Rodney; Chavan, Abhijeet, Using implanted sensors for feedback control of implanted medical devices.
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