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Method of suppressing tumor growth with combinations of isoprenoids and statins 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/355
  • A61K-031/12
출원번호 US-0027546 (1998-02-23)
발명자 / 주소
  • Elson Charles E.
출원인 / 주소
  • Wisconsin Alumni Research Foundation
대리인 / 주소
    Quarles & Brady LLP
인용정보 피인용 횟수 : 12  인용 특허 : 17

초록

A method of inhibiting the growth of tumor cells is disclosed. In one embodiment, this method comprises the step of exposing tumor cells to an effective amount of a composition comprising at least two compounds selected from the group consisting of tocotrienols, statins and ionones.

대표청구항 ▼

[ I claim:] [1.] A method of inhibiting the growth of a tumor sensitive to the combination of ionone and tocotrienol within a patient comprising the step of orally administer to the patient an effective amount of a composition comprising tocotrienol and ionone, wherein the amount is effective to inh

이 특허에 인용된 특허 (17)

  1. Pearce Bradley C. (East Hampton CT) Wright John J. (Guilford CT), Antihyperlipidemic/antioxidant dihydroquinolines.
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  2. Pearce Bradley C. (East Hampton CT) Wright John J. (Guilford CT), Cholesterol lowering/antioxidant nitroxides.
    상세보기
  3. Samid Dvorit (Rockville MD), Compositions and methods for treating and preventing pathologies including cancer.
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  4. Mattson Fred H. (San Diego CA), Compositions for inhibiting absorption of cholesterol.
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  5. Bacon Dennis R. (Milford OH) Trinh Toan (Maineville OH), Detergent compositions containing enduring perfume.
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  6. Bradfute David L. (Wooster OH) Simoni Robert D. (Palo Alto CA), Farnesyl compounds as cholesterol lowering agents.
    상세보기
  7. Pearce Bradley C. (East Hampton CT), Farnesylated tetrahydro-naphthalenols as hypolipidemic agents.
    상세보기
  8. Scavone Timothy A. (Maineville OH) Braun ; deceased James L. (late of Cincinnati OH by Pauletta Mary Braun ; legal representative), High temperature vacuum steam distillation process to purify and increase the frylife of edible oils.
    상세보기
  9. Tan Barrie (Amherst MA) Saleh Mohammed H. (Amherst MA), Integrated process for recovery of carotenoids and tocotrienols from oil.
    상세보기
  10. Perricone Nicholas V. (35 Pleasant St. - Suite 2A Meriden CT 06450), Method and compositions for topical application of ascorbic acid fatty acid esters for treatment and/or prevention of sk.
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  11. Perricone Nicholas V. (27 Coginchaug Ct. Guilford CT 06437), Method and compositions for topical application to the skin for prevention and/or treatment of radiation-induced skin da.
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  12. Perricone Nicholas V. (35 Pleasant St. 0 Suite 2A Meriden CT 06450), Method and compositions for treatment and/or prevention of skin damage and aging.
    상세보기
  13. Top Abdul G. Md. (Kuala Lumpur) Leong Leong W. (Shah Alam) Ong Augustine S. H. (Kuala Lumpur MYX) Kawada Tsukasa (Tokyo JPX) Watanabe Hisashi (Tokyo JPX) Tsuchiya Nozomu (Tokyo JPX), Production of high concentration tocopherols and tocotrienols from palm-oil by-products.
    상세보기
  14. Pearce Bradley C. (East Hampton CT), Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia.
    상세보기
  15. Lane Ronald H. (Phoenix AZ) Qureshi Asaf A. (Madison WI) Salser Winston A. (Pacific Palisades CA), Tocotrienols and tocotrienol-like compounds and methods for their use.
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  16. Wright John J. (North Guilford CT) Pearce Bradley C. (East Hampton CT) Parker Rex (Branford CT) Qureshi Asaf A. (Madison WI), Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders.
    상세보기
  17. Jandacek Ronald J. (Cincinnati OH) Mattson Fred H. (San Diego CA) Taylor Harry M. (Cincinnati OH), Vitaminized compositions for treating hypercholesterolemia.
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이 특허를 인용한 특허 (12)

  1. Bessette,Steven M.; Enan,Essam E., Cancer treatment composition and method using natural plant essential oils.
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  2. Mo,Huanbiao; Elson,Charles E.; Peffley,Dennis M.; Hentosh,Patricia M., Composition and method for treating cancer.
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  3. Guthrie, Najla, Compositions and methods for glycemic control of subjects with impaired fasting glucose.
    상세보기
  4. Guthrie, Najla, Compositions and methods for glycemic control of subjects with impaired fasting glucose.
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  5. Guthrie Najla,CAX ; Kurowska Elzbieta Maria,CAX, Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols.
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  6. Compadre, Cesar M.; Breen, Philip; Aykin-Burns, Nukhet; Hauer-Jensen, Martin; Enriquez, Raul G.; Kharade, Sujay; Malagon, Omar; Ordonez, Yadira; Ojeda, Edgar; Thakkar, Shraddha; Pineda, E. Nathalie; Jones, Darin, Preparation and use of a composition for prevention and mitigation of the effects of radiation.
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  7. Sanders, Bob G.; Kline, Kimberly; Hurley, Daurence; Gardner, Robb; Menchaca, Marla; Yu, Weiping; Ramanan, Puthucode N.; Liu, Shenquan; Israel, Karen, Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof.
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  8. Sanders, Bob G.; Kline, Kimberly; Yu, Weiping, Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof.
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  9. Sanders, Bob G.; Kline, Kimberly; Yu, Weiping, Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof.
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  10. Sanders, Bob G.; Kline, Kimberly; Yu, Weiping, Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof.
    상세보기
  11. Sanders,Bob G.; Kline,Kimberly; Hurley,Laurence; Gardner,Robb; Menchaca,Marla; Yu,Weiping; Ramanan,Puthucode N.; Liu,Shenquan; Israel,Karen, Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof.
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  12. Sanders,Bob G.; Kline,Kimberly; Yu,Weiping, Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof.
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