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Composition for therapy of diseases with ultrasonic and pharmaceutical liquid composition containing the same 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61B-008/00
출원번호 US-0652690 (1996-05-30)
우선권정보 JP0058970 (1991-03-22)
발명자 / 주소
  • Tachibana Katsuro,JPX
  • Tachibana Shunro,JPX
출원인 / 주소
  • EKOS Corporation
대리인 / 주소
    Weitz
인용정보 피인용 횟수 : 78  인용 특허 : 14

초록 ▼

A booster comprising a plenty of microbubbles of a gas in a liquid, e.g. about 4.times.10.sup.7 cells/ml of microbubbles of a gas having a diameter of 0.1 to 100 .mu.m in a 3 to 5% human serum albumin solution, and a pharmaceutical liquid composition comprising the booster as set forth above and a m

대표청구항 ▼

[ What is claim is:] [1.] A .[.booster.]. .Iadd.composition .Iaddend.for enhancing effects of ultrasound in the therapy of diseases, which comprises:.Iadd.a liquid; .Iaddend..[.a..]. a medicament.Iadd.; .Iaddend.and.[.b..]. microbubbles of a gas having a diameter of 0.1 to 100 .mu.m.Iadd., .Iaddend.

이 특허에 인용된 특허 (14)

  1. Hilmann Juergen (Berlin DEX) Hoffmann Rolf-Ruediger (Berlin DEX) Muetzel Wolfgang (Berlin DEX) Zimmermann Ingfried (Berlin DEX), Carrier liquid solutions for the production of gas microbubbles, preparation thereof, and use thereof as contrast medium.
    상세보기
  2. Line Bruce R. (Delmar NY) Weber Peter B. (Delmar NY), Complex for in-vivo target localization.
    상세보기
  3. Widder Kenneth J. (Del Mar CA) Westkaemper Peter J. (San Diego CA), Concentrated stabilized microbubble-type ultrasonic imaging agent.
    상세보기
  4. Guess Joe F. (Estes Park CO) Zalesky Paul J. (Huntington Beach CA), Intravascular ultrasonic angioplasty probe.
    상세보기
  5. Ryan Patrick J. (Worcester MA) Davis Michael A. (Westwood MA) Melchior Donald L. (Framingham MA), Lipisomes containing gas for ultrasound detection.
    상세보기
  6. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same.
    상세보기
  7. Barenholz Yechezkel (Jerusalem CA ILX) Gabizon Alberto (San Francisco CA), Lipsome/anthraquinone drug composition and method.
    상세보기
  8. Katakura Kageyoshi (Tokyo JPX), Method and apparatus for the measurement and medical treatment using an ultrasonic wave.
    상세보기
  9. D\Arrigo Joseph S. (Farmington CT), Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and the.
    상세보기
  10. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes.
    상세보기
  11. Rasor Julia S. (Cupertino CA) Tickner Ernest G. (Gilroy CA), Microbubble precursors and apparatus for their production and use.
    상세보기
  12. Kung Viola T. (Menlo Park CA) Redemann Carl T. (Walnut Creek CA), Protein-liposome conjugates.
    상세보기
  13. Feinstein Steven B. (295 Hasting Ave. Highland Park IL 60035), Ultrasonic imaging agent and method of preparation.
    상세보기
  14. Stasz Peter (Moundsview MN), Ultrasonically enhanced RF ablation catheter.
    상세보기

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  3. Gifford, III, Hanson; Deem, Mark; Boyd, Stephen, Aortic valve repair.
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  4. Babaev,Eilaz, Apparatus and method for the treatment of tissue with ultrasound energy by direct contact.
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  5. Babaev, Eilaz, Apparatus and methods for debridement with ultrasound energy.
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  6. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Apparatus for reducing the appearance of cellulite.
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  7. Deem, Mark E.; Gifford, III, Hanson S.; Sutton, Douglas, Apparatus for treating subcutaneous tissues.
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  10. Cordemans de Meulenaer, Eric; Hannecart, Baudouin; Canivet, Yves, Device and process for treating a liquid medium.
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  11. de Meulenaer,Eric Cordemans; Hannecart,Baudouin; Canivet,Yves, Device and process for treating a liquid medium.
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  12. Swinnen,Mario; Cordemans de Meulenaer,Eric D.; Hannecart,Baudouin O.; Beardwood,Edward S., Device and process for treating cutting fluids using ultrasound.
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  13. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Device for dissection of subcutaneous tissue.
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  14. de Meulenaer,Eric Cordemans; Hannecart,Baudouin; Gottschalk,Kevin M., Devices and method for treating cooling fluids utilized in tire manufacturing.
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  15. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Devices and methods for performing subcutaneous surgery.
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  16. Merchant, Adnan I.; Deem, Mark E., Devices and methods for selectively lysing cells.
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  17. de Meulenaer, Eric Cordemans; Swinnen, Mario; Gosker, Jan Reinier; Hannecart, Baudouin, Devices and methods for treating fluids utilized in electrocoating processes with ultrasound.
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  18. Swinnen, Mario; Moffat, Harold; Beardwood, Edward S.; Hannecart, Baudouin; Cordemans de Meulenaer, Eric D., Devices and processes for use in ultrasound treatment.
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  19. Morriss, John; Gifford, III, Hanson; Fann, James I.; Dueri, Jean-Pierre; Gittings, Darin; Luna, Michael; Deem, Mark; Sutton, Douglas, Devices, systems and methods for heart valve replacement.
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  20. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Dissection handpiece and method for reducing the appearance of cellulite.
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  21. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Dissection handpiece and method for reducing the appearance of cellulite.
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  22. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Dissection handpiece and method for reducing the appearance of cellulite.
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  23. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Dissection handpiece and method for reducing the appearance of cellulite.
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  24. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Dissection handpiece and method for reducing the appearance of cellulite.
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  25. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Dissection handpiece with aspiration means for reducing the appearance of cellulite.
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  26. Davidson,Michael, Enhancement of transfection of DNA into the liver.
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  28. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Handpiece and methods for performing subcutaneous surgery.
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  29. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., Handpiece for use in tissue dissection.
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  30. Deem, Mark; Gifford, III, Hanson; Morriss, John; McLean, Matt; Luna, Michael, Hydraulic delivery systems for prosthetic heart valve devices and associated methods.
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  31. Deem, Mark; Gifford, III, Hanson; Morriss, John; McLean, Matt; Luna, Michael, Hydraulic delivery systems for prosthetic heart valve devices and associated methods.
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  32. Gifford, III, Hanson, Implant heart valve devices, mitral valve repair devices and associated systems and methods.
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  41. Deem, Mark E.; Gifford, III, Hanson S.; Sutton, Douglas, Methods and system for treating subcutaneous tissues.
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  47. Cordemans De Meulenaer, Eric D.; Hannecart, Baudouin; Canivet, Yves, Process for treating a liquid medium using ultrasound.
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  48. Morriss, John; Gifford, III, Hanson, Prosthetic heart valve devices and associated systems and methods.
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  50. Morriss, John; Gifford, III, Hanson, Prosthetic heart valve devices and associated systems and methods.
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  55. Morriss, John; Gifford, III, Hanson; Fann, James I.; Dueri, Jean-Pierre; McLean, Matt; Gittings, Darin; Luna, Michael; Deem, Mark; Sutton, Douglas; Grainger, Jeffry J., Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods.
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  56. Morriss, John; Gifford, III, Hanson; Fann, James I.; Dueri, Jean-Pierre; McLean, Matt; Gittings, Darin; Luna, Michael; Deem, Mark; Sutton, Douglas; Grainger, Jeffry J., Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods.
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  57. Babaev, Eilaz; Peterson, Michael T.; Van Houten, Alan; Doten, Greg, Removable applicator nozzle for ultrasound wound therapy device.
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  58. Babaev, Eilaz; Van Houten, Alan; Peterson, Michael T.; Doten, Greg, Removable applicator nozzle for ultrasound wound therapy device.
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  61. Coles, Eric; Davidson, Michael, Sonochemical induction of ABCA1 expression and compositions therefor.
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  62. Deem, Mark E.; Gifford, III, Hanson S.; Sutton, Douglas S., System and method for treating subcutaneous tissues.
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  64. Gifford, III, Hanson S.; Fann, James I.; Morriss, John; Deem, Mark; Grainger, Jeffry J., System for mitral valve repair and replacement.
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  65. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F., System for tissue dissection and aspiration.
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  70. Babaev, Eliaz, Ultrasonic catheter drug delivery method and device.
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  75. Soltani, Azita; Prokop, Adrian F., Ultrasound therapy system.
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