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Process for preparing microparticles through phase inversion phenomena 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B01J-013/04
  • B01J-013/06
출원번호 US-0686928 (1996-07-03)
발명자 / 주소
  • Mathiowitz Edith
  • Chickering
  • III Donald
  • Jong Yong S.
  • Jacob Jules S.
출원인 / 주소
  • Brown University Foundation
대리인 / 주소
    Wolf, Greenfield & Sacks, P.C.
인용정보 피인용 횟수 : 76  인용 특허 : 25

초록 ▼

A process for preparing nanoparticles and microparticles is provided. The process involves forming a mixture of a polymer and a solvent, wherein the solvent is present in a continuous phase and introducing the mixture into an effective amount of a nonsolvent to cause the spontaneous formation of mic

대표청구항 ▼

[ What we claim is:] [1.] A method for microencapsulating an agent to form a microencapsulated product, comprising:dissolving a polymer in an effective amount of a solvent,dissolving or dispersing said agent in said effective amount of said solvent, wherein said polymer, said agent and said solvent

이 특허에 인용된 특허 (25)

  1. Grinstaff Mark W. (Pasadena CA) Soon-Shiong Patrick (Los Angeles CA) Wong Michael (Champaign IL) Sandford Paul A. (Los Angeles CA) Suslick Kenneth S. (Champaign IL) Desai Neil P. (Los Angeles CA), Composition useful for in vivo delivery of biologics and methods employing same.
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  2. Wellman Russel E. (Pittsford NY) Brown Robert W. (Rochester NY), Encapsulation process.
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  3. Abatjoglou Anthony G. (Charlestown WV) Bryant David R. (So. Charleston WV), Hydroformylation using low volatile phosphine ligands.
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  4. Kuehnle Adelheid R. (1617 Keeaumoku St. #1008 Honolulu HI 96822) Kuehnle Manfred R. (Waldesruh Rte. 103A ; P.O. Box 1020 New London NH 03257), Magnetophoretic particle delivery method and apparatus for the treatment of cells.
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  5. Fitzpatrick-McElligott Sandra G. (Media PA) Lavin John G. (Swarthmore PA) Rivard Germain F. (Philadelphia PA) Subramoney Shekhar (Hockessin DE), Method for introducing a biological substance into a target.
    상세보기
  6. Violante Michael R. (Rochester NY) Fischer Harry W. (Pittsford NY), Method for making uniformly-sized particles from insoluble compounds.
    상세보기
  7. Sanford John C. (Geneva NY) Wolf Edward D. (Ithaca NY) Allen Nelson K. (Newfield NY), Method for transporting substances into living cells and tissues and apparatus therefor.
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  8. Tice Thomas R. (Birmingham AL) Gilley Richard M. (Birmingham AL) Eldridge John H. (Birmingham AL) Staas Jay K. (Birmingham AL) Hollingshead Melinda G. (Birmingham AL) Shannon William M. (Birmingham A, Method of potentiating an immune response.
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  9. Tice Thomas R. (Birmingham AL) Gilley Richard M. (Birmingham AL), Microencapsulation process and products therefrom.
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  10. Chang James N. (Irvine CA), Monolithic maleic anhydride drug delivery systems.
    상세보기
  11. Meadows David L. (Mission Viejo CA), Nonaqueous fluorinated drug delivery vehicle suspensions.
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  12. Meadows David L. (Mission Viejo CA), Nonaqueous thixotropic drug delivery suspensions and methods of their use.
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  13. Boyes Robert N. (St. Albans AL GB2) Tice Thomas R. (Birmingham AL) Gilley Richard M. (Birmingham AL) Pledger Kenneth L. (Huntsville AL), Pharmaceutical formulations comprising microcapsules.
    상세보기
  14. McGinity James W. (Austin TX) Iwata Motokazu (Osaka JPX), Preparation and uses of multi-phase microspheres.
    상세보기
  15. Morishita Masataka (Shizuoka JA) Inaba Yoshihito (Shizuoka JA) Fukushima Mitsuru (Shizuoka JA) Kobari Sadami (Shizuoka JA) Nagata Akiho (Shizuoka JA) Abe Jinnosuke (Shizuoka JA), Preparation of microcapsules.
    상세보기
  16. Mathiowitz Edith (Brookline MA) Langer Robert S. (Somerville MA), Preparation of multiwall polymeric microcapsules.
    상세보기
  17. Samejima, Masayoshi; Hirata, Goichi; Ishibashi, Takashi, Process for preparing free-flowing ethylcellulose microcapsules.
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  18. Spenleuhauer Gilles,FRX ; Bazile Didier,FRX ; Veillard Michel,FRX ; Prud'Homme Christian,FRX ; Michalon Jean-Paul,FRX, Process for preparing nanoparticles.
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  19. Fessi Curt (Paris FRX) Devissaguet Jean-Philippe (Neuilly S/Seine FRX) Puisieux Francis (Maisons Alfort MO FRX) Thies Curt (St. Louis MO), Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles.
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  20. Devissaguet Jean-Philippe (Neuilly sur Seine FRX) Fessi Hatem (Paris FRX) Puisieux Francis (Maisons Alfort FRX), Process for the preparaton of dispersible colloidal systems of a substance in the form of nanocapsules.
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  21. Gardner David L. (Bellville OH), Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or e 상세보기
  • Samulski Richard J. (Pittsburgh PA) Xiao Xiao (Pittsburgh PA), Recombinant viral vector system.
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  • Long Robert B. (Atlantic Highlands NJ) Griffel Jack (Sarnia CAX), Selective removal of coke precursors from hydrocarbon feedstock.
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  • Kossovsky Nir (Los Angeles CA) Hnatyszyn H. James (Los Angeles CA) Gelman Andrew (Los Angeles CA), Targeted transfection nanoparticles.
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  • Violante Michael R. ; Parker Kevin J., Ultrasmall, non-aggregated porous particles of uniform size for entrapping gas bubbles within and methods.
    상세보기

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