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Tocotrienols and tocotrienol-like compounds and methods for their use 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/355
  • A61K-031/455
  • C07D-021/132
  • C07D-031/104
출원번호 US-0182531 (1998-10-28)
발명자 / 주소
  • Lane Ronald H.
  • Qureshi Asaf A.
  • Salser Winston A.
출원인 / 주소
  • Lipogenics, Inc.
대리인 / 주소
    Lyon & Lyon LLP
인용정보 피인용 횟수 : 26  인용 특허 : 12

초록 ▼

The present invention relates to novel tocotrienols and tocotrienol-like compounds displaying biological activity. The tocotrienols and tocotrienol-like compounds of this invention may be conveniently obtained from biological sources or by chemical synthesis and may be used in pharmaceutical composi

대표청구항

[ We claim:] [1.] A composition comprising a tocotrienol or a mixture thereof and nicotinic acid or a nicotinic acid derivative or conjugate.

이 특허에 인용된 특허 (12)

  1. Wang, Jonas C. T., Compositions and method for stabilization of anthralin comprising the addition of an oil soluble antioxidant and an anionic surfactant.
    상세보기
  2. Ohgaki Kazunari (Nara JPX) Katayama Takashi (Toyonaka JPX), Extractive separation method.
    상세보기
  3. Pearce Bradley C. (East Hampton CT), Farnesylated tetrahydro-naphthalenols as hypolipidemic agents.
    상세보기
  4. Pearce Bradley C. (East Hampton CT), Farnesylated tetrahydro-naphthalenols as hypolipidemic agents.
    상세보기
  5. Schmidt Douglass N. (Grosse Ile MI), Free-flowing, high density, fat soluble vitamin powders with improved stability.
    상세보기
  6. Marshall Lisa A. (Wayne PA) Steiner Kurt E. (Devon PA) Schiehser Guy A. (Malvern PA), Phospholipase A2 inhibitors.
    상세보기
  7. Pearce Bradley C. (East Hampton CT), Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia.
    상세보기
  8. Lane Ronald H. (Phoenix AZ) Qureshi Asaf A. (Madison WI) Salser Winston A. (Pacific Palisades CA), Tocotrienols and tocotrienol-like compounds and methods for their use.
    상세보기
  9. Lane Ronald H. ; Qureshi Asaf A. ; Salser Winston A., Tocotrienols and tocotrienol-like compounds and methods for their use.
    상세보기
  10. Lane Ronald H. ; Qureshi Asaf A. ; Salser Winston A., Tocotrienols and tocotrienol-like compounds and methods for their use.
    상세보기
  11. Wright John J. (North Guilford CT) Pearce Bradley C. (East Hampton CT) Parker Rex (Branford CT) Qureshi Asaf A. (Madison WI), Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders.
    상세보기
  12. Wright John J. (North Guilford CT) Pearce Bradley C. (East Hampton CT) Parker Rex (Branford CT) Qureshi Asaf A. (Madison WI), Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders.
    상세보기

이 특허를 인용한 특허 (26)

  1. West, Simon Michael; Ogru, Esra; Gianello, Robert, Alkaloid formulations.
    상세보기
  2. Berry Christopher J.,THX ; Bierenbaum Marvin L., Anticholesterolemic edible oil.
    상세보기
  3. West, Simon Michael; Kannar, David, Carrier.
    상세보기
  4. Libinaki, Roksan, Carrier comprising non-neutralised tocopheryl phosphate.
    상세보기
  5. Gavin, Paul; Gianello, Robert; Ogru, Esra, Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof.
    상세보기
  6. Libinaki, Roksan, Composition.
    상세보기
  7. Libinaki, Roksan, Composition comprising non-neutralised tocol phosphate and a vitamin A compound.
    상세보기
  8. Guthrie, Najla, Compositions and methods for glycemic control of subjects with impaired fasting glucose.
    상세보기
  9. Guthrie, Najla, Compositions and methods for glycemic control of subjects with impaired fasting glucose.
    상세보기
  10. Guthrie Najla,CAX ; Kurowska Elzbieta Maria,CAX, Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols.
    상세보기
  11. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  12. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  13. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  14. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  15. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  16. Brian Keller, Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase-2.
    상세보기
  17. Keller,Brian, Compounds and methods for inhibition of phospholipase Aand cyclooxygenase-2.
    상세보기
  18. West, Simon Michael; Verdicchio, Robert J.; Kannar, David; Mills, Jr., Otto H., Dermal therapy using phosphate derivatives of electron transfer agents.
    상세보기
  19. West, Simon Michael, Formulation containing phosphate derivatives of electron transfer agents.
    상세보기
  20. West, Simon Michael, Formulation containing phosphate derivatives of electron transfer agents.
    상세보기
  21. Bromley, Philip J., Formulations of water-soluble derivatives of vitamin E and compositions containing same.
    상세보기
  22. Gregory R. Mundy ; I. Ross Garrett ; Gloria E. Gutierrez, Nutritional supplements for stimulating bone growth.
    상세보기
  23. Compadre, Cesar M.; Breen, Philip; Aykin-Burns, Nukhet; Hauer-Jensen, Martin; Enriquez, Raul G.; Kharade, Sujay; Malagon, Omar; Ordonez, Yadira; Ojeda, Edgar; Thakkar, Shraddha; Pineda, E. Nathalie; Jones, Darin, Preparation and use of a composition for prevention and mitigation of the effects of radiation.
    상세보기
  24. Howard, Luke, Process of producing purified gamma- and delta-tocotrienols from tocol-rich oils or distillates.
    상세보기
  25. Cottrell, Jeremy; Gaetano, Giacinto; El-Tamimy, Mahmoud; Kennedy, Nicholas; Gavin, Paul David, Transdermal delivery patch.
    상세보기
  26. Cottrell, Jeremy; Gaetano, Giacinto; El-Tamimy, Mahmoud; Kennedy, Nicholas; Gavin, Paul David, Transdermal delivery patch.
    상세보기

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