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Taste of active pharmaceutical ingredients 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/14
출원번호 US-0180022 (1998-10-30)
국제출원번호 PCT/EP97/01781 (1997-04-10)
§371/§102 date 19981030 (19981030)
국제공개번호 WO-9741835 (1997-11-13)
발명자 / 주소
  • Schwarz Eugen,DEX
  • Moschl Gernot,DEX
  • Tallavajhala Siva
출원인 / 주소
  • Merck Patent Gesellschaft mit, DEX
대리인 / 주소
    Millen, White, Zelano & Branigan, P.C.
인용정보 피인용 횟수 : 49  인용 특허 : 1

초록

The invention relates to a process for improving the taste of solid formulations containing one or more active ingredients.

대표청구항 ▼

[ What is claimed is:] [1.] A method for improving the flavor profile of a solid formulation which comprises one or more active substances, comprising co-spray drying said active substance(s) and at least one polyol, wherein the polyol is dissolved in water, and the active substance(s) are dissolved

이 특허에 인용된 특허 (1)

  1. Kirk Paula S. (Dearborn Heights MI) Olson Dale R. (Riverview MI), Process for making a spray-dried, directly-compressible vitamin powder comprising unhydrolyzed gelatin.
    상세보기

이 특허를 인용한 특허 (49)

  1. Redmond, Mark J.; Fielder, David A., Cereal β glucan compositions, methods of preparation and uses thereof.
    상세보기
  2. Olsen, Peder M.; Christensen, Karin L.; Sørensen, Dina W., Chewable, suckable and swallowable tablet containing a calcium-containing compound as an active substance.
    상세보기
  3. Norman, Gary T.; Nuguru, Kalyan S.; Amin, Arun F.; Chandar, Sarath, Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms.
    상세보기
  4. Norman, Gary T.; Nuguru, Kalyan S.; Amin, Arun F.; Chandar, Sarath, Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms.
    상세보기
  5. Norman,Gary Telfer; Nuguru,Kalyan S.; Amin,Arun F.; Chandar,Sarath, Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms.
    상세보기
  6. Dang, Phuong Grace; Lawrence, Brian D.; Balwani, Gul; D'Addio, Alexander D., Compositions comprising azelastine.
    상세보기
  7. Dang, Phuong Grace; Lawrence, Brian D.; Balwani, Gul; D'Addio, Alexander D., Compositions comprising azelastine and methods of use thereof.
    상세보기
  8. Dang, Phuong Grace; Lawrence, Brian D.; Balwani, Gul; D'Addio, Alexander D., Compositions comprising azelastine and methods of use thereof.
    상세보기
  9. Fuge, Dennis; Higson, John; Roecklein, Bryan A.; Balwani, Gul; D'Addio, Alexander D., Compositions comprising azelastine and methods of use thereof.
    상세보기
  10. Balwani, Gul; Sacks, Harry J.; Roecklein, Bryan A.; Johns, Benjamin, Compositions comprising carisoprodol and methods of use thereof.
    상세보기
  11. Hanna, Mazen H.; York, Peter, Compositions of particulate coformulation.
    상세보기
  12. Prakash, Indra; DuBois, Grant E., Condiments with high-potency sweetener.
    상세보기
  13. Platz, Robert M.; Brewer, Thomas K.; Boardman, Terence D., Dispersible macromolecule compositions and methods for their preparation and use.
    상세보기
  14. Olsen, Peder Mohr; Bertelsen, Poul Egon; Thisted, Thomas; Aage, Henrik Ravn, Dissolution stability of calcium carbonate tablets.
    상세보기
  15. Olsen, Peder Mohr; Bertelsen, Poul Egon; Thisted, Thomas; Aage, Henrik Ravn, Dissolution stability of calcium carbonate tablets.
    상세보기
  16. Bertelsen, Poul Egon; Olsen, Peder Mohr; Nielsen, Carsten Martini; Tolleshaug, Magnus Wilhelm, Fast wet-massing method for the preparation of calcium-containing compositions.
    상세보기
  17. Piene, Jan Y., Film-coated and/or granulated calcium-containing compounds and use thereof in pharmaceutical compositions.
    상세보기
  18. Piene, Jan Yngvar, Film-coated and/or granulated calcium-containing compounds and use therof in pharmaceutical compositions.
    상세보기
  19. Prakash, Indra; DuBois, Grant E., High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith.
    상세보기
  20. Tillotson, John; Propst, Cecil, Highly compactable and durable direct compression excipients and excipient systems.
    상세보기
  21. Tillotson, John; Propst, Cecil, Highly compactable and durable direct compression excipients and excipient systems.
    상세보기
  22. Bertelsen, Poul Egon; Olsen, Peder Mohr; Nielsen, Carsten Martini; Tolleshaug, Magnus Wilhelm, Melt granulation of a composition containing a calcium-containing compound.
    상세보기
  23. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
    상세보기
  24. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
    상세보기
  25. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
    상세보기
  26. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
    상세보기
  27. Cook, Robert O.; Shrewsbury, Stephen B.; Ramadan, Nabih N.; Armer, Thomas A., Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile.
    상세보기
  28. Mathiesen, Jacob; Nielsen, Carsten Martini; Olsen, Peder Mohr; Bertelsen, Poul Egon, Particulate comprising a calcium-containing compound and a sugar alcohol.
    상세보기
  29. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
    상세보기
  30. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
    상세보기
  31. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
    상세보기
  32. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
    상세보기
  33. Kordikowski, Andreas; Walker, Stephen Ernest; York, Peter, Particulate materials.
    상세보기
  34. York, Peter; Shekunov, Boris Yu; Rehman, Mahboob Ur; Feeley, Jane Catherine, Particulate materials.
    상세보기
  35. York, Peter; Shekunov, Boris Yu; Rehman, Mahboob Ur; Feeley, Jane Catherine, Particulate materials.
    상세보기
  36. York, Peter; Shekunov, Boris Yu; Rehman, Mahboob Ur; Feeley, Jane Catherine, Particulate materials.
    상세보기
  37. Vehring, Reinhard; Miller, Danforth P.; Lechuga-Ballesteros, David, Pharmaceutical formulation comprising a water-insoluble active agent.
    상세보기
  38. Vehring, Reinhard; Miller, Danforth P; Lechuga-Ballesteros, David, Pharmaceutical formulation comprising a water-insoluble active agent.
    상세보기
  39. Bertelsen, Poul Egon; Olsen, Peder Mohr, Pre-compacted calcium-containing compositions.
    상세보기
  40. Kulkarni, Sunanda R.; McFadden, Robert T.; Rogers, David H.; Walter, Jr., James T., Preblend of microcrystalline cellulose and lactase for making tablets.
    상세보기
  41. Snyder, Herman E.; Nasiatka, James; Varga, Christopher M., Prefilming atomizer.
    상세보기
  42. Snyder, Herman E; Nasiatka, James; Varga, Christopher M, Prefilming atomizer.
    상세보기
  43. Piene, Jan Yngvar; Schmidt, Dina Dogger, Process for preparing oral calcium compositions.
    상세보기
  44. Johal, Sarjit; Pollmeier, Albert J., Salt composition.
    상세보기
  45. Snyder, Herman E.; Vosberg, Michael J.; Varga, Christopher M., Spray drying methods and related compositions.
    상세보기
  46. Snyder, Herman E; Vosberg, Michael J; Varga, Christopher M, Spray drying methods and related compositions.
    상세보기
  47. Bennett, David B.; Brewer, Thomas K.; Platz, Robert M.; Snyder, Herman, Spray drying process control of drying kinetics.
    상세보기
  48. Bennett, David B; Brewer, Thomas K; Platz, Robert M; Snyder, Herman, Spray drying process control of drying kinetics.
    상세보기
  49. Gordon, Marc S.; Clark, Andrew; Brewer, Thomas K., Systems and processes for spray drying hydrophobic and hydrophilic components.
    상세보기

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