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Local administration of type III phosphodiesterase inhibitors for the treatment of erectile dysfunction 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/50
출원번호 US-0437682 (1999-11-10)
발명자 / 주소
  • Doherty
  • Jr. Paul C.
  • Place Virgil A.
  • Smith William L.
출원인 / 주소
  • Vivus, Inc.
대리인 / 주소
    Reed
인용정보 피인용 횟수 : 56  인용 특허 : 11

초록

A method is provided for treating erectile dysfunction, e.g., vasculogenic erectile dysfunction such as vasculogenic impotence. The method involves the administration of a Type III phosphodiesterase inhibitor or a pharmaceutically acceptable salt, ester, amide or derivative thereof, wherein administ

대표청구항

[ What is claimed is:] [1.] A method for treating erectile dysfunction in a male individual, comprising administering to the individual a therapeutically effective amount of a pharmaceutical formulation comprised of a Type III phosphodiesterase inhibitor or a pharmaceutically acceptable salt, ester,

이 특허에 인용된 특허 (11)

  1. Hamilton Harriet W. (Chelsea MI), 5-Substituted pyrazolo[4,3-d]pyrimidine-7-ones and methods of use.
  2. Broughton Barbara Joyce (Croydon EN) Large Bryan John (Ilkley EN) Marshall Stuart Malcolm (Stanford-Le-Hope EN) Pain David Lord (Upminster EN) Wooldridge Kenneth Robert Harry (Brentwood EN), Azapurinones.
  3. Broughton Barbara Joyce (Croydon EN) Large Bryan John (Ilkley EN) Marshall Stuart Malcolm (Stanford-le-Hope EN) Pain David Lord (Upminster EN) Wooldridge Kenneth Robert Harry (Brentwood EN), Azapurinones.
  4. Voss Gene (213 Alcade Moreno San Antonio TX 78232) Eichler Allen C. (1347 Lockhill-Selma San Antonio TX 78213), Impotence ointment.
  5. Erion Mark D. (Del Mar CA) Ugarkar Bheemarao G. (Escondido CA) Castellino Angelo J. (San Diego CA), Lyxofuranosyl analogues of adenosine.
  6. Bell Andrew S. (Deal GBX) Brown David (Nr Canterbury GBX) Terrett Nicholas K. (Deal GBX), Pyrazolopyrimidinone antianginal agents.
  7. Bell Andrew S. (Groton CT) Brown David (Groton CT) Terrett Nicholas K. (Groton CT), Pyrazolopyrimidinone antianginal agents.
  8. Bell Andrew S. (Groton CT) Terrett Nicholas K. (Groton CT), Pyrazolopyrimidinone antianginal agents.
  9. Bell Andrew S. (Groton CT) Terrett Nicholas K. (Groton CT), Pyrazolopyrimidinone antianginal agents.
  10. Place Virgil A. (Kawaihae HI) Gale Robert M. (Los Altos CA) Berggren Randall G. (Livermore CA), Urethral insert for treatment of erectile dysfunction.
  11. Virag Ronald (5 ; avenue Clodoald F-92210 Saint-Cloud FRX), Vaso-active medicament to treat impotence.

이 특허를 인용한 특허 (56)

  1. Barlow, Carrolee; Carter, Todd; Morse, Andrew; Treuner, Kai; Lorrain, Kym I., 5 HT receptor mediated neurogenesis.
  2. Leland F. Wilson ; Paul C. Doherty, Jr. ; Virgil A. Place ; William L. Smith ; Ibrahim AbouBakr Abdel-Hamid Abdou Ali EG, Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation.
  3. Combrink, Keith D.; Mohapatra, Suchismita; Hellberg, Mark R.; Sharif, Najam A.; Prasanna, Ganesh; Pang, Iok-Hou; Severns, Bryon; Chen, Hwang-Hsing; Namil, Abdelmoula, Bradykinin receptor agonists and uses thereof to treat ocular hypertension and glaucoma.
  4. Barlow, Carrolee; Carter, Todd A.; Morse, Andrew; Treuner, Kai; Lorrain, Kym I., Combinations containing a 4-acylaminopyridine derivative.
  5. Hyde, Roderick A.; Ishikawa, Muriel Y.; Wood, Jr., Lowell L., Condoms configured to facilitate release of nitric oxide.
  6. Hyde, Roderick A.; Ishikawa, Muriel Y.; Stordal, Leif T.; Wood, Jr., Lowell L., Devices and systems that deliver nitric oxide.
  7. Hyde, Roderick A.; Ishikawa, Muriel Y.; Stordal, Leif T.; Wood, Jr., Lowell L., Devices and systems that deliver nitric oxide.
  8. Armer, Thomas; McKinley, Geoff; Borland, Scott; Guzman, Miguel; Szabolcs, Ármin; Gerencser, János, Ergoline compounds and uses thereof.
  9. Armer, Thomas; McKinley, Geoff; Borland, Scott; Guzman, Miguel; Szabolcs, Ármin; Gerencser, János, Ergoline compounds and uses thereof.
  10. Armer, Thomas; McKinley, Geoff; Borland, Scott; Guzman, Miguel; Szabolcs, Ármin; Gerencser, János, Ergoline compounds and uses thereof.
  11. Armer, Thomas; McKinley, Geoff; Borland, Scott; Guzman, Miguel; Szabolcs, Ármin; Gerencser, János, Ergoline compounds and uses thereof.
  12. DiPerna, Paul M, Flow regulating stopcocks and related methods.
  13. DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
  14. DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
  15. Michaud, Michael; Kruse, Geoffrey A., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
  16. Michaud, Michael; Kruse, Geoffrey A., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
  17. Verhoef, Erik T.; DiPerna, Paul M.; Rosinko, Mike; Williamson, Mark; Kruse, Geoffrey A.; Ulrich, Thomas R.; Lamb, Phil; Saint, Sean; Michaud, Michael; Trevaskis, William, Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
  18. Armer, Thomas; McKinley, Geoff; Borland, Scott; Guzman, Miguel, Isoergoline compounds and uses thereof.
  19. Armer, Thomas; McKinley, Geoff; Borland, Scott; Guzman, Miguel, Isoergoline compounds and uses thereof.
  20. Armer, Thomas; McKinley, Geoff; Borland, Scott; Guzman, Miguel, Isoergoline compounds and uses thereof.
  21. Arthur W. Wallace, L-arginine and phosphodiesterase (PDE) inhibitor synergism.
  22. Hanson, Stephen R., Methods and compositions for treating platelet-related disorders.
  23. Rosinko, Michael J.; DiPerna, Paul M., Methods and devices for determination of flow reservoir volume.
  24. Rosinko, Michael J; DiPerna, Paul M., Methods and devices for determination of flow reservoir volume.
  25. Hyde, Roderick A.; Ishikawa, Muriel Y.; Wood, Jr., Lowell L., Methods and systems for use of photolyzable nitric oxide donors.
  26. Hyde, Roderick A.; Ishikawa, Muriel Y.; Wood, Jr., Lowell L., Methods and systems for use of photolyzable nitric oxide donors.
  27. Barlow, Carrolee; Carter, Todd A.; Lorrain, Kym I.; Pires, Jammieson C.; Treuner, Kai, Modulation of neurogenesis by PDE inhibition.
  28. Hyde, Roderick A.; Ishikawa, Muriel Y.; Wood, Jr., Lowell L., Nitric oxide permeable housings.
  29. Hyde, Roderick A.; Ishikawa, Muriel Y.; Stordal, Leif T.; Wood, Jr., Lowell L., Nitric oxide sensors and systems.
  30. Cutler, Neal R., PDE III inhibitors for treating sexual dysfunction.
  31. Dudley, Robert E.; Drouin, Dominique, Pharmaceutical composition and method for treating hypogonadism.
  32. Dudley, Robert E.; Drouin, Dominique, Pharmaceutical composition and method for treating hypogonadism.
  33. Dudley, Robert E.; Kottayil, S. George; Palatchi, Olivier, Pharmaceutical composition and method for treating hypogonadism.
  34. Liao, Yihua; Zhao, Zhong; Araldi, Gian Luca, Pyrrolidine derivatives as prostaglandin modulators.
  35. Liao, Yihua; Zhao, Zhong; Araldi, Gian Luca, Pyrrolidine derivatives as prostaglandin modulators.
  36. Liao,Yihua; Zhao,Zhong; Araldi,Gian Luca, Pyrrolidine derivatives as prostaglandin modulators.
  37. Franklin, Richard, Quinazoline derivatives and their use in the treatment of thrombocythemia.
  38. DiPerna, Paul M., Slideable flow metering devices and related methods.
  39. Brown, David, Solute concentration measurement device and related methods.
  40. Forsell, Peter, Stimulation of penis erection.
  41. Franklin, Richard; Golding, Bernard T.; Cicala, Peter A., Substituted quinazolines for reducing platelet count.
  42. Hyde, Roderick A.; Ishikawa, Muriel Y.; Stordal, Leif T.; Wood, Jr., Lowell L., Substrates for nitric oxide releasing devices.
  43. Hyde, Roderick A.; Ishikawa, Muriel Y.; Stordal, Leif T.; Wood, Jr., Lowell L., Substrates for nitric oxide releasing devices.
  44. Rosinko, Michael J.; Kruse, Geoffrey A.; Harris, Paul, System and method for detecting occlusions in an infusion pump.
  45. Hyde, Roderick A.; Ishikawa, Muriel Y.; Wood, Jr., Lowell L., Systems and devices that utilize photolyzable nitric oxide donors.
  46. Metzmaker, Thomas; Saint, Sean; Michaud, Michael; Rosinko, Michael J.; Swanson, Vance, Systems including vial adapter for fluid transfer.
  47. Malladi, Ramana; Miller, Jodi, Testosterone gel and method of use.
  48. Malladi, Ramana; Miller, Jodi, Testosterone gel and method of use.
  49. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  50. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  51. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  52. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  53. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  54. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
  55. Neal R. Cutler, Treatment of sexual dysfunction in certain patient groups.
  56. DiPerna, Paul M., Two chamber pumps and related methods.
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