초록 ▼

The disclosed invention relates to an improved electrotransport device. The improvement relates to a membrane assembly including a low porosity membrane adhered or sealed to one or two high porosity membranes. The high porosity membranes protect the low porosity membrane from being damaged by compon

The disclosed invention relates to an improved electrotransport device. The improvement relates to a membrane assembly including a low porosity membrane adhered or sealed to one or two high porosity membranes. The high porosity membranes protect the low porosity membrane from being damaged by components or contaminates on the body surface and/or in the drug reservoir which can lead to undesirable passive flux and/or insufficient iontophoretic flux. As a result, the electrotransport device having the membrane assembly more reliably, precisely, and accurately delivers drug and/or therapeutic agent through the body surface by electrotransport.

대표청구항 ▼

[ Wherein, what is claimed is:] [1.] An electrotransport device for delivering a therapeutic agent through a body surface comprising:a controller,a power source,a counter electrode assembly, andat least one donor electrode assembly including an electrode, a donor reservoir containing the agent, and

[ Wherein, what is claimed is:] [1.] An electrotransport device for delivering a therapeutic agent through a body surface comprising:a controller,a power source,a counter electrode assembly, andat least one donor electrode assembly including an electrode, a donor reservoir containing the agent, and a membrane assembly located on the body surface distal side of the donor electrode assembly, said membrane assembly comprising:a first membrane having a first average pore size, porosity, pore size distribution, and spatial pore distribution affixed toa second membrane having a second average pore size, porosity, pore size distribution, and spatial pore distribution,wherein the first porosity is less than the second porosity.