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Agents and methods for enhancing contrast in ultrasound imaging 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61B-005/055
출원번호 US-0474468 (1995-06-07)
우선권정보 DE3803972 (1988-02-05)
발명자 / 주소
  • Stein Michael,DEX
  • Heldmann Dieter,DEX
  • Fritzsch Thomas,DEX
  • Siegert Joachim,DEX
  • Roessling Georg,DEX
출원인 / 주소
  • Schering Aktiengesellschaft, DEX
대리인 / 주소
    Millen, White, Zelano & Branigan, P.C.
인용정보 피인용 횟수 : 51  인용 특허 : 39

초록

The invention relates to ultrasonic contrast agents comprising microparticles which comprise synthetic biodegradable polymers and a gas and/or a fluid with a boiling point below 60.degree. C., processes for the preparation thereof and their use as diagnostic and therapeutic agents.

대표청구항 ▼

[ What is claimed is:] [1.] A method of enhancing an ultrasound image of a liquid which comprises administering an effective amount of an ultrasound imaging contrast agent to said liquid and obtaining an ultrasound image of said liquid, said ultrasound imaging contrast agent comprising:(i) micropart

이 특허에 인용된 특허 (39)

  1. Hilmann Juergen (Berlin DEX) Hoffmann Rolf-Ruediger (Berlin DEX) Muetzel Wolfgang (Berlin DEX) Zimmermann Ingfried (Berlin DEX), Carrier liquid solutions for the production of gas microbubbles, preparation thereof, and use thereof as contrast medium.
    상세보기
  2. Rypcek Frantisek (Praha CSX) Uher Jan (Praha CSX) Drobnk Jaroslav (Praha CSX), Composition for diagnosing the transport function of the fallopian tube and a method for preparing said composition.
    상세보기
  3. Widder Kenneth J. (Del Mar CA) Westkaemper Peter J. (San Diego CA), Concentrated stabilized microbubble-type ultrasonic imaging agent.
    상세보기
  4. Feinstein Steven B. (295 Hasting Ave. Highland Park IL 60035), Contrast agents for ultrasonic imaging.
    상세보기
  5. Berwing Klaus (Bad Nauheim DEX) Schlepper Martin (Bad Nauheim DEX), Contrast medium for ultrasonic examinations and process for its preparation.
    상세보기
  6. Schroder Ulf (Lund SEX) Salford Leif G. (Lund SEX), Diagnostic and contrast agent.
    상세보기
  7. Miller Robert C. (Penn Hills Township ; Allegheny County PA), Electrically driven meter totalizing device.
    상세보기
  8. Moriya Tadashi (Hachioji JPX) Seki Masahiro (Tokyo JPX) Nakamura Toshiomi (Yokohama JPX), Gas containing contrast agent particles having external magnetic layer.
    상세보기
  9. Ryan Patrick J. (Worcester MA) Davis Michael A. (Westwood MA) Melchior Donald L. (Framingham MA), Lipisomes containing gas for ultrasound detection.
    상세보기
  10. Lee Richard T. (Weston MA), Medical ultrasound contrast agent and method of using same.
    상세보기
  11. Tickner Ernest G. (Morgan Hill CA), Method of determining pressure within liquid containing vessel.
    상세보기
  12. Temple ; Rodger G., Method of preparing microcapsules.
    상세보기
  13. Rasor Julia S. (Cupertino CA) Tickner Ernest G. (Gilroy CA), Method of production and use of microbubble precursors.
    상세보기
  14. Levene Harold B. (San Diego CA) Villapando Elaine (San Diego CA) Barnhart James L. (Encinitas CA) Widder Kenneth J. (Del Mar CA), Method of ultrasound imaging of the gastrointestinal tract.
    상세보기
  15. Quay Steven C. (Los Angeles CA), Methods for selecting and using gases as ultrasound contrast media.
    상세보기
  16. Rasor Julia S. (Cupertino CA) Tickner Ernest G. (Gilroy CA), Microbubble precursors and apparatus for their production and use.
    상세보기
  17. Rasor Julia S. (Cupertino CA) Tickner Ernest G. (Gilroy CA), Microbubble precursors and methods for their production and use.
    상세보기
  18. Wismer Marco (Gibsonia PA) Seiner Jerome A. (Pittsburgh PA), Microcapsular opacifiers and method for their production.
    상세보기
  19. Vassiliades Anthony E. (Deerfield IL) Shroff Shrenik (Lake Forest IL) Nauman Edward F. (Chicago IL), Oil-in-water emulsions containing hydropholeic starch.
    상세보기
  20. Kreighbaum William E. (Evansville IN) Comer William T. (Evansville IN), Phenyltetrazolyloxy propanolamines.
    상세보기
  21. Vanderhoff John W. (345 9th Ave. Bethlehem PA 18018) El-Aasser Mohamed S. (1201 N. Maxwell St. Allentown PA 18103) Ugelstad John (SINTEF ; 7034 Trondheim-NTH Trondheim NOX), Polymer emulsification process.
    상세보기
  22. Glajch Joseph L. (Nashua NH) Loomis Gary L. (Drexel Hill PA) Mahler Walter (Wilmington DE), Porous inorganic ultrasound contrast agents.
    상세보기
  23. De Luca Patrick P. (Lexington KY) Rypacek Frantisek (Leckova CZX), Preparation of biodegradable microspheres useful as carriers for macromolecules.
    상세보기
  24. Couvreur Patrick (Wavre BEX) Roland Michel (Brussels BEX) Speiser Peter (Forch CHX), Preparation of submicroscopic particles, particles thus obtained and pharmaceutical compositions containing them.
    상세보기
  25. Ziemelis Maris J. (Midland MI), Process for preparing silicone microparticles.
    상세보기
  26. Stainmesse Serge (Choisy le Roi FRX) Fessi Hatem (Paris FRX) Devissaguet Jean-Philippe (Neuilly sur Seine FRX) Puisieux Francis (Maisons-Alfort FRX), Process for the preparation of dispersible colloidal systems of amphiphilic lipids in the form of oligolamellar liposome.
    상세보기
  27. Devissaguet Jean-Philippe (Neuilly sur Seine FRX) Fessi Hatem (Paris FRX) Puisieux Francis (Maisons Alfort FRX), Process for the preparaton of dispersible colloidal systems of a substance in the form of nanocapsules.
    상세보기
  28. Margel, Shlomo; Beitler, Uzi, Process for the production of polyacrolein microspheres and grafted microspheres.
    상세보기
  29. Gardner David L. (Bellville OH), Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or e 상세보기
  • Osuna Carillo de Albornoz Antonio (Granada ESX) Castanys Santiago (Granada ESX), Therapeutic agents in the form of submicroscopic particles against Leishmaniasis and pharmaceutical compositions contain.
    상세보기
  • Schroder Ulf (Lund SEX), Ultrasonic contrast agent comprising carbohydrate particles.
    상세보기
  • Reinhardt Michael (Berlin DEX) Fritzsch Thomas (Berlin DEX) Heldmann Dieter (Berlin DEX) Siegert Joachim (Berlin DEX), Ultrasonic contrast agents for color Doppler imaging.
    상세보기
  • Erbel Raimund (Mainz DEX) Zotz Rainer (Mainz DEX) Krone Volker (Flrsheim DEX) Magerstdt Michael (Hofheim am Taunus DEX) Walch Axel (Frankfurt am Main DEX), Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents.
    상세보기
  • Rasor Ned S. (Cupertino CA) Hilmann Jurgen (Berlin DEX) Lange Lothar (Berlin DEX) Fritzsch Thomas (Berlin DEX) Siegert Joachim (Berlin DEX) Zimmermann Ingfried (Weiler DEX), Ultrasonic contrast medium comprising gas bubbles and solid lipophilic surfactant-containing microparticles and use ther.
    상세보기
  • Kaneko Nagao (Yokohama JPX) Wada Moriyasu (Ninomiya JPX) Saitoh Shiroh (Yokohama JPX) Honda Hiroki (Yokohama JPX), Ultrasonic coupling agent.
    상세보기
  • Tickner Ernest G. (Morgan Hill CA) Rasor Ned S. (Santa Clara County CA), Ultrasonic image enhancement.
    상세보기
  • Feinstein Steven B. (295 Hasting Ave. Highland Park IL 60035), Ultrasonic imaging agent and method of preparation.
    상세보기
  • Schlief Reinhard (Berlin) Poland Hans (Berlin DEX), Ultrasonic manometry process in a fluid by means of microbubbles.
    상세보기
  • Rothman ; Ulf Sven Erik, X-ray contrast preparation containing a hydrophilic polymer containing amino groups.
    상세보기

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