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Powdered pharmaceutical formulations having improved dispersibility 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/14
출원번호 US-0903658 (1997-07-31)
발명자 / 주소
  • Eljamal Mohammed
  • Patton John S.
  • Foster Linda C.
  • Platz Robert M.
출원인 / 주소
  • Inhale Therapeutic Systems
대리인 / 주소
    Evans
인용정보 피인용 횟수 : 56  인용 특허 : 2

초록

Dispersibility of a respirable powder, administrable by inhalation, is increased by including a pharmaceutically acceptable water-soluble polypeptide.

대표청구항 ▼

[ The claimed subject matter is:] [1.] A spray-dried dispersible powdered composition suitable for inhalation by a human subject, comprising:(a) a therapeutically effective amount of an active agent suitable for treating a condition in said subject by inhalation;(b) a pharmaceutically-acceptable exc

이 특허에 인용된 특허 (2)

  1. Platz Robert M. (Half Moon Bay CA) Ip Anna (Moorpark CA) Whitham Clyde L. (Montara CA), Process for preparing micronized polypeptide drugs.
    상세보기
  2. Pitt Colin G. (Thousand Oaks CA) Platz Robert M. (Half Moon Bay CA), Pulmonary administration of erythropoietin.
    상세보기

이 특허를 인용한 특허 (56)

  1. Pavkov, Richard M.; Armer, Thomas A.; Mohsen, Nahed M., Aerosol air flow control system and method.
    상세보기
  2. Cox, Kenneth A.; Beane, Timothy Paul; Sweeney, William R., Aerosol generator and methods of making and using an aerosol generator.
    상세보기
  3. Cox, Kenneth A.; Beane, Timothy Paul; Sweeney, William R.; Nichols, Walter A.; Sprinkel, Jr., F. Murphy, Aerosol generator and methods of making and using an aerosol generator.
    상세보기
  4. Cox,Kenneth A.; Beane,Timothy Paul; Sweeney,William R.; Nichols,Walter A.; Sprinkel, Jr.,F. Murphy, Aerosol generator and methods of making and using an aerosol generator.
    상세보기
  5. Sprinkel, Jr., F. Murphy; Nichols, Walter A., Aerosol generator having a multiple path heater arrangement and method of use thereof.
    상세보기
  6. Sherwood, Timothy S.; Sowers, Scott A.; Reddy, Sirisha P.; Sprinkel, Jr., F. Murphy; Cox, Kenneth A.; Nichols, Walter A., Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate.
    상세보기
  7. Sprinkel, Jr., F. Murphy; Nichols, Walter A.; Cox, Kenneth A.; Sherwood, Timothy S.; Sowers, Scott A.; Washington, Zelita R.; Reddy, Sirisha, Aerosol generator having heater in multilayered composite and method of use thereof.
    상세보기
  8. Sharpe, David E.; Felter, John L., Aerosol generator having inductive heater and method of use thereof.
    상세보기
  9. Kenneth A. Cox ; Walter A. Nichols ; F. Murphy Sprinkel, Jr. ; Douglas D. McRae ; William R. Sweeney, Aerosol generator having multiple heating zones and methods of use thereof.
    상세보기
  10. Cox,Kenneth A.; Nichols,Walter A.; Sprinkel, Jr.,F. Murphy; McRae,Douglas D.; Sweeney,William R., Aerosol generator having temperature controlled heating zone and method of use thereof.
    상세보기
  11. Hunt, John F.; Gaston, Benjamin M., Airway alkalinization as a therapy for airway diseases.
    상세보기
  12. Hunt, John F.; Gaston, Benjamin M., Airway alkalinization as therapy for airway diseases.
    상세보기
  13. Nichols, Walter A.; Sprinkel, Jr., F. Murphy, Disposable aerosol generator system and methods for administering the aerosol.
    상세보기
  14. Nichols,Walter A.; Sprinkel, Jr.,F. Murphy, Disposable aerosol generator system and methods for administering the aerosol.
    상세보기
  15. Nichols,Walter A.; Sprinkel, Jr.,F. Murphy, Disposable inhaler system.
    상세보기
  16. Nichols,Walter A.; Sprinkel, Jr.,F. Murphy, Disposable inhaler system.
    상세보기
  17. Yadidi, Kambiz, Dry powder formulations and methods of use.
    상세보기
  18. Yadidi, Kambiz, Dry powder formulations for inhalation.
    상세보기
  19. Yadidi, Kambiz, Dry powder inhaler and methods of use.
    상세보기
  20. Yadidi, Kambiz, Dry powder inhaler and methods of use.
    상세보기
  21. Nichols, Walter A.; Cox, Kenneth A.; Nguyen, Tung Tien, Dual capillary fluid vaporizing device.
    상세보기
  22. Nichols, Walter A.; Cox, Kenneth A.; Nguyen, Tung Tien, Dual capillary fluid vaporizing device.
    상세보기
  23. Tarara, Thomas E.; Weers, Jeffry G.; Kabalnov, Alexey; Schutt, Ernest G.; Dellamary, Luis A., Engineered particles and methods of use.
    상세보기
  24. Tarara,Thomas E.; Weers,Jeffry G.; Kabalnov,Alexey; Schutt,Ernest G.; Dellamary,Luis A., Engineered particles and methods of use.
    상세보기
  25. Faison, Jr.,Gene G.; Gupta,Rajiv; McRae,Douglas D.; Nichols,Walter A., Fluid vaporizing device having controlled temperature profile heater/capillary tube.
    상세보기
  26. Nichols, Walter A.; Cox, Kenneth A.; McRae, Douglas D.; Nguyen, Tung Tien, Fluid vaporizing device having controlled temperature profile heater/capillary tube.
    상세보기
  27. Tarara, Thomas E.; Weers, Jeffry G.; Eldon, Michael A.; Narashimhan, Rangachari; Clark, Andrew, Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use.
    상세보기
  28. Lipp, Michael W.; Batycky, Richard P.; Caponetti, Giovanni, Formulation for spray-drying large porous particles.
    상세보기
  29. Altboum, Zeev; Levine, Myron M.; Barry, Eileen M., Isolation and characterization of the csa operon (ETEC-CS4 pili) and methods of using same.
    상세보기
  30. Altboum,Zeev; Levine,Myron M.; Barry,Eileen M., Isolation and characterization of theoperon (ETEC-CS4 pili) and methods of using same.
    상세보기
  31. Byron,Peter R.; Hindle,Michael, Method and apparatus for generating an aerosol.
    상세보기
  32. Hindle, Michael; Byron, Peter R.; Gupta, Rajiv, Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution.
    상세보기
  33. Patton, John S.; Foster, Linda S.; Platz, Robert M., Methods and compositions for pulmonary delivery of insulin.
    상세보기
  34. Xu, Kai Yuan, Methods of inhibiting platelet aggregation and preventing thrombosis using antibodies that bind (Na++K+)-ATPase beta subunit.
    상세보기
  35. Hindle, Michael; Byron, Peter R.; Hong, John N., Mouthpiece entrainment airflow control for aerosol generators.
    상세보기
  36. Edwards, David A.; Hrkach, Jeffrey S., Particles for inhalation having sustained release properties.
    상세보기
  37. Batycky,Richard P.; Edwards,David A.; Lipp,Michael M., Particulate compositions for pulmonary delivery.
    상세보기
  38. Batycky,Richard P.; Edwards,David A.; Lipp,Michael M., Particulate compositions for pulmonary delivery.
    상세보기
  39. Weers, Jeffry G.; Tarara, Thomas E.; Dellamary, Luis A.; Riess, Jean G.; Schutt, Ernest G., Phospholipid-based powders for drug delivery.
    상세보기
  40. Weers, Jeffry G; Tarara, Thomas E; Dellamary, Luis A; Riess, Jean G; Schutt, Ernest G, Phospholipid-based powders for drug delivery.
    상세보기
  41. Patton,John S., Pulmonary delivery of active fragments of parathyroid hormone.
    상세보기
  42. Tarara, Thomas E.; Weers, Jeffry G.; Venthoye, Geraldine, Pulmonary delivery of aminoglycoside.
    상세보기
  43. Tarara, Thomas E; Weers, Jeffry G; Venthoye, Maria Geraldine, Pulmonary delivery of aminoglycoside.
    상세보기
  44. Tarara, Thomas E.; Weers, Jeffrey G.; Kabalnov, Alexey; Schutt, Ernest G.; Dellamary, Luis A., Pulmonary delivery particles comprising an active agent.
    상세보기
  45. Weers, Jeffry G.; Schutt, Ernest G.; Dellamary, Luis A.; Tarara, Thomas E.; Kabalnov, Alexey, Respiratory dispersion for metered dose inhalers comprising perforated microstructures.
    상세보기
  46. Roser, Bruce J.; Kampinga, Jaap; Colaco, Camilo; Blair, Julian, Solid dose delivery vehicle and methods of making same.
    상세보기
  47. Roser, Bruce J.; Kampinga, Jaap; Colaco, Camilo; Blair, Julian, Solid dose delivery vehicle and methods of making same.
    상세보기
  48. Roser, Bruce J.; Kampinga, Jaap; Colaco, Camilo; Blair, Julian, Solid dose delivery vehicle and methods of making same.
    상세보기
  49. Weers, Jeffry G.; Schutt, Ernest G.; Dellamary, Luis; Tarara, Thomas E.; Kabalnov, Alexey, Stabilized preparations for use in metered dose inhalers.
    상세보기
  50. Dellamary, Luis A.; Reiss, Jean; Schutt, Ernest G.; Weers, Jeffry G.; Tarara, Thomas E., Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery.
    상세보기
  51. Dellamary, Luis A.; Riess, Jean; Schutt, Ernest G.; Weers, Jeffry G.; Tarara, Thomas E., Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use.
    상세보기
  52. Dellamary, Luis A; Riess, Jean; Schutt, Ernest G; Weers, Jeffry G; Tarara, Thomas E, Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use.
    상세보기
  53. Edwards, David A.; Hrkach, Jeffrey S., Stable spray-dried protein formulations.
    상세보기
  54. Batycky,Richard P.; Lipp,Michael M.; Niven,Ralph W., Use of simple amino acids to form porous particles.
    상세보기
  55. Batycky, Richard P.; Lipp, Michael M.; Niven, Ralph W., Use of simple amino acids to form porous particles during spray drying.
    상세보기
  56. Walter A. Nichols, Vapor driven aerosol generator and method of use thereof.
    상세보기

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