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Apparatus for performing assays on liquid samples accurately, rapidly and simply 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/53
  • G01N-033/531
  • G01N-033/543
  • G01N-033/545
출원번호 US-0819341 (1997-03-18)
발명자 / 주소
  • Oberhardt Bruce
출원인 / 주소
  • Cardiovascular Diagnostics, Inc.
대리인 / 주소
    Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
인용정보 피인용 횟수 : 78  인용 특허 : 9

초록

An element and method for easily performing liquid assays are disclosed. The element uses capillary action to draw a predetermined volume of a liquid sample into a reaction chamber charged with reagent, where reaction between the liquid sample and the reagent is monitored.

대표청구항

[What is claimed as new and desired to be secured by Letters Patent of the United States is:] [1.]

이 특허에 인용된 특허 (9)

  1. Lilja ; Jan E. ; Nilsson ; Sven E. L., Apparatus for sampling, mixing the sample with a reagent and making particularly optical analyses.
  2. Hillman Robert S. (Cupertino CA) Cobb Michael E. (Sunnyvale CA) Allen Jim (Los Altos CA) Gibbons Ian (Menlo Park CA) Ostoich Vladimir (San Jose CA) Winfrey Laura J. (Belmont CA), Capillary flow device.
  3. Rapkin Myron C. (Cupertino CA) Schoengold Ronald J. (San Jose CA) Shockey David R. (San Jose CA) Van Rysselberghe Pierre C. (Palo Alto CA), Device and method for whole blood separation and analysis.
  4. Oberhardt Bruce (Raleigh NC), Immunoassay system using forced convection currents.
  5. Columbus Richard L. (Rochester NY), Liquid transport device and method.
  6. Columbus Richard L. (Rochester NY), Multi-analyte test device.
  7. Oberhardt Bruce (Raleigh NC), Reaction system element and method for performing prothrombin time assay.
  8. Berger Dieter (Mannheim DEX) Biegel Elke (Mannheim DEX) Frey Gnter (Ellerstadt DEX) Murawski Hans-Rdiger (Lampertheim DEX), Test carrier.
  9. Blatt Joel M. (Granger IN) Heiland Robert (Goshen IN) Morris James R. (South Bend IN) Pugh Jerry (Elkhart IN) Wogoman Frank W. (South Bend IN), Volume metering capillary gap device for applying a liquid sample onto a reactive surface.

이 특허를 인용한 특허 (78)

  1. Sterling, Bernhard B.; Braig, James R.; Witte, Kenneth G.; Rule, Peter; Keenan, Richard; Hall, W. Dale, Analyte detection system for multiple analytes.
  2. Braig, James R.; Rule, Peter; Hartstein, Philip C.; Sterling, Bernhard B.; Gable, Jennifer H.; Li, Kenneth I., Analyte monitoring systems and methods.
  3. Braig, James R.; Rule, Peter; Hartstein, Philip C.; Sterling, Bernhard B.; Gable, Jennifer H.; Li, Kenneth I., Analyte monitoring systems and methods.
  4. Rule, Peter; Rivas, Gil, Analyte monitoring systems and methods.
  5. Large, Timothy Andrew; Gifford, Graham Eric; Marriott, Stephen Paul, Analytical apparatus.
  6. Taguchi,Takayuki; Kitamura,Shigeru, Analytical instrument.
  7. Fujimoto, Koji; Kitamura, Shigeru; Hori, Masaki, Analyzing article, analyzer and method of analyzing a sample using the analyzing article, and a method of forming an opening in the analyzing article.
  8. Kram, Brian Howard; Marshall, Kevin David; Otter, Michael; Martin, Carl David; Jones, Jessica, Arcuate member for moving liquids along a microscope slide.
  9. Kram, Brian Howard; Marshall, Kevin David; Otter, Michael; Martin, Carl David; Jones, Jessica, Arcuate member for moving liquids along a microscope slide.
  10. Oberhardt, Bruce, Assay card for an assay chamber.
  11. Nazeer H. Shareef ; Jack L. Zuidema, Assay test system for regulating temperature.
  12. Shareef,Nazeer H.; Smous,James E.; Albarella,James P., Assay test system for regulating temperature.
  13. LaCourt,Michael W.; Shaw,James David; Avdenko,Michael; David,Lee William; Ryan,Dale Robert, Auxiliary sample supply for a clinical analyzer.
  14. Clague,Cynthia T.; Cheek,Daniel S.; Nippoldt,Douglas D., Blood coagulation test cartridge, system, and method.
  15. Nippoldt,Douglas D.; Clague,Cynthia T.; Ericson,Daniel G., Blood coagulation test cartridge, system, and method.
  16. Wright,David W.; Kriewall,Timothy J.; Cheek,Daniel S., Blood coagulation test cartridge, system, and method.
  17. Forsell, Tommy, Blood viscosity analysis.
  18. Gable, Jennifer H.; Braig, James R.; Li, Kenneth I.; Wechsler, Mark; Zheng, Peng; Keenan, Richard, Bodily fluid composition analyzer with disposable cassette.
  19. Gable, Jennifer H.; Braig, James R.; Li, Kenneth I.; Wechsler, Mark; Zheng, Peng; Keenan, Richard, Bodily fluid composition analyzer with disposable cassette.
  20. Leonard, Leslie; Drese, Klaus Stefan; Boecker, Dirk, Capillary flow for a heterogenous assay in a micro-channel environment.
  21. Baudenbacher, Franz; Mernaugh, Raymond; Mayo, John; Lubbers, Brad; Wiley, Robert G., Device and method for detecting a target analyte.
  22. Braig,James R.; Rule,Peter; Hartstein,Philip C.; Sterling,Bernard B.; Gable,Jennifer H.; Li,Kenneth I., Device and method for in vitro determination of analyte concentrations within body fluids.
  23. Mueller, Bruno; Bird, William E., Display unit and methods of displaying an image.
  24. Esfandiari, Javanbakhsh, Dual path immunoassay device.
  25. Esfandiari, Javanbakhsh, Dual path immunoassay device.
  26. Esfandiari, Javanbakhsh, Dual path immunoassay device.
  27. Esfandiari, Javanbakhsh, Dual path immunoassay device.
  28. Esfandiari, Javanbakhsh, Dual path immunoassay device.
  29. Esfandiari,Javanbakhsh, Dual path immunoassay device.
  30. Teodorczyk,Maria; Kiser,Ernest J.; Olson,Lorin P.; McAllister,Devin; Yuzhakov,Vadim V.; Leong,Koon wah, Electrochemical test strip with an integrated micro-needle and associated methods.
  31. Horiuchi, Tsutomu; Miura, Toru; Iwasaki, Yuzuru; Takahashi, Jyunichi; Hayashi, Katsuyoshi; Haga, Tsuneyuki; Seyama, Michiko; Camou, Serge, Flow cell and method for manufacturing the same.
  32. Drewes,Joel A.; Bogart,Gregory R.; Etter,Jeffrey B.; Steaffens,Jeffrey W.; Ostroff,Rachel M.; Crosby,Mark, Flow-through optical assay devices providing laminar flow of fluid samples, and methods of construction thereof.
  33. Lim, Eugene; Tong, Roger; Rule, Peter; Braig, James R.; Keenan, Richard; Callicoat, David N., Fluid analysis system.
  34. Lim, Eugene; Tong, Roger; Rule, Peter; Braig, James R.; Keenan, Richard; Callicoat, David N., Fluid analysis system.
  35. Gable, Jennifer H.; Braig, James R.; Li, Kenneth I.; Wechsler, Mark; Zheng, Peng; Keenan, Richard, Fluid handling cassette.
  36. Gable, Jennifer H.; Braig, James R.; Li, Kenneth I.; Wechsler, Mark; Zheng, Peng; Keenan, Richard, Fluid handling cassette having a spectroscopic sample cell.
  37. Keenan, Richard; Chiou, Jeff; Gable, Jennifer; Li, Ken; Tong, Roger; Recknor, Mike; Braig, James R., Fluid handling cassette system for body fluid analyzer.
  38. Keenan, Richard; Chiou, Jeffrey; Gable, Jennifer; Li, Kenneth I-Shen; Tong, Roger; Recknor, Mike; Braig, James R., Fluid handling cassette system for body fluid analyzer.
  39. Leonard, Edward F.; Reich, Ilan K.; Cortell, Stanley, Fluid separation devices, systems and methods.
  40. Esfandiari, Javanbakhsh, Immunoassay methods utilizing trapping conjugate.
  41. Esfandiari, Javanbakhsh, Immunoassay utilizing trapping conjugate.
  42. Braig, James R.; Rule, Peter; Hartstein, Philip C.; Sterling, Bernhard B.; Gable, Jennifer H.; Li, Kenneth I., In vitro determination of analyte levels within body fluids.
  43. Braig, James R.; Rule, Peter; Hartstein, Phillip C.; Sterling, Bernhard B.; Gable, Jennifer H.; Li, Kenneth I., In vitro determination of analyte levels within body fluids.
  44. Adey,Nils B., Laminated microarray interface device.
  45. Rule,Peter; Braig,James R.; Hartstein,Philip C., Layered spectroscopic sample element with microporous membrane.
  46. Mize, Patrick D., Low molecular weight heparin assay, system and reagent therefor.
  47. Meisegeier, Bernhard; Zwingmann, Detlev; Oberstrass, Jurgen; Schaper, Reinhard, Measuring device and measuring method for detecting analytes.
  48. Harding, Ian; Iyengar, Sridhar G.; Nguyen, Ha; Williams, Richard, Method and apparatus for monitoring alteration of flow characteristics in a liquid sample.
  49. Harding, Ian; Iyengar, Sridhar G.; Nguyen, Ha; Williams, Richard, Method and apparatus for monitoring alteration of flow characteristics in a liquid sample.
  50. Harding, Ian; Iyengar, Sridhar G.; Nguyen, Ha; Williams, Richard; Rao, Anoop, Method and apparatus for monitoring alteration of flow characteristics in a liquid sample.
  51. Grzeda,Barbara R.; Maggiore,Jack A., Method and device for measurement of hematocrit.
  52. McNeely,Michael; Adey,Nils; Spute,Mark; Ayliffe,Edward; Howard,Michael; Beutel,Darin; Jensen,John; Coffin,Stephen; Moyer,Thomas, Method and system for microfluidic interfacing to arrays.
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  54. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang, Methods of blood-based therapies having a microfluidic membraneless exchange device.
  55. Otter, Michael; Kram, Brian Howard; Martin, Carl David; Jones, Jessica; Marshall, Kevin David; Tse, Christine; Harrison, Josh, Opposables and automated specimen processing systems with opposables.
  56. Follonier, Stéphane; Fan, Linsey; Indermuhle, Pierre, Pipette tip, pipette system and method for performing analysis with the pipette tip and system.
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  58. Braig,James R.; Rule,Peter; Gaffney,Robert D.; Hartstein,Philip C.; Cortella,Julian M.; Li,Kenneth I.; Sterling,Bernhard B.; Zheng,Peng; Hall,W. Dale; Witte,Kenneth G.; Agostino,Mark D.; Goldberger,D, Reagent-less whole-blood glucose meter.
  59. Esfandiari, Javanbakhsh, Reduced step dual path immunoassay device and method.
  60. Rule, Peter; Braig, James R.; Hartstein, Philip C.; Gable, Jennifer H., Sample adapter.
  61. Lim, Eugene; Tong, Roger, Sample cell for fluid analysis system.
  62. Hirao, Konomu; Murata, Yasuhito, Specimen analyzing implement.
  63. Raz Ryan S.,CAX ; Robertson Gordon,CAX, System for biological specimen preparation.
  64. Rule, Peter; Causey, III, James D., Systems and methods for detecting leaks.
  65. Rule, Peter; Braig, James R.; Keenan, II, Richard; Callicoat, David, Systems and methods for measuring multiple analytes in a sample.
  66. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang, Systems and methods for membraneless dialysis.
  67. Chiou, Pei Yu; Wu, Ming C., Systems and methods for optical actuation of microfluidics based on OPTO-electrowetting.
  68. Chiou, Pei Yu; Wu, Ming C., Systems and methods for optical actuation of microfluidics based on opto-electrowetting.
  69. Leonard, Edward F.; West, Alan C.; Shaplely, Nina C.; Tang, Zhongliang, Systems and methods of blood-based therapies having a microfluidic membraneless exchange device.
  70. Leonard, Edward F.; West, Alan C.; Shapley, Nina C.; Tang, Zhongliang, Systems and methods of blood-based therapies having a microfluidic membraneless exchange device.
  71. Leonard, Edward F.; West, Alan C.; Aucoin, Christian P.; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  72. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  73. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  74. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  75. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  76. Leonard, Edward F.; West, Alan C.; Aucoin, Christian Paul; Nanne, Edgar E., Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams.
  77. Kram, Brian Howard; Marshall, Kevin David; Tse, Christine; Keller, Timothy James; Ashby, Austin Micheil, Thin film processing apparatuses for adjustable volume accommodation.
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