$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Multiblock biodegradable hydrogels for drug delivery and tissue treatment 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C08L-053/00
  • C08L-051/00
  • A61K-009/00
출원번호 US-0692914 (1996-07-26)
발명자 / 주소
  • Pathak Chandrashekhar P.
  • Barman Shikha P.
  • Philbrook C. Michael
  • Sawhney Amarpreet S.
  • Coury Arthur J.
  • Avila Luis Z.
  • Kieras Mark T.
출원인 / 주소
  • Focal, Inc.
대리인 / 주소
    Arnall Golden & Gregory, LLP
인용정보 피인용 횟수 : 173  인용 특허 : 44

초록

Gel-forming macromers including at least four polymeric blocks, at least two of which are hydrophobic and at least one of which is hydrophilic, and including a crosslinkable group are provided. The macromers can be covalently crosslinked to form a gel on a tissue surface in vivo. The gels formed fro

대표청구항

[What is claimed is:] [1.]a) at least one polymer block is hydrophilic and each hydrophilic polymer block individually has a water solubility of at least 1 gram/liter;b) at least two blocks are sufficiently hydrophobic to cause the macromer to aggregate to form micelles in an aqueous continuous phas

이 특허에 인용된 특허 (44)

  1. Langdon William K. (Grosse Ile MI), Acetal group-containing non-ionic surfactants.
  2. Langdon William K. (Grosse Ile MI), Alkali stable polyoxyethylene acetal surfactants.
  3. Langdon William K. (Grosse Ile MI), Amine-coupled polyepichlorohydrin and polyamines derived therefrom.
  4. Steiner Carol A. (1166 Hope St. #6 Stamford CT 06907), Associative polymer hydrogels.
  5. Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.
  6. DeLuca Patrick P. (Lexington KY) Rypacek Frantisek (Leckova CSX), Biodegradable microspheres as a carrier for macromolecules.
  7. Slepian Marvin J. (Cleveland Heights OH) Schindler Anton (Durham NC), Biodegradable polymeric endoluminal sealing process.
  8. Cohn Daniel (Jerusalem ILX) Younes Hani (Ara-Meshulush ILX) Uretzky Gideon (Jerusalem ILX), Biodegradable polymeric materials based on polyether glycols, processes for the preparation thereof and surgical article.
  9. Nair Mridula (Penfield NY) Yoo Youngtai (Seoul KRX), Chemically fixed micelles.
  10. Kopecek Jindrich (Salt Lake City UT) Kim Sung W. (Salt Lake City UT) Brondsted Helle (Salt Lake City UT) Kopeckova Pavla (Salt Lake City UT), Colonic-targeted oral drug-dosage forms based on crosslinked hydrogels containing azobonds and exhibiting PH-dependent s.
  11. Churchill Jeffrey R. (Northwich GBX) Hutchinson Francis G. (Lymm GBX), Continuous release formulations.
  12. Langer Robert S. (Sommerville MA) Domb Abraham J. (Brookline MA) Laurencin Cato T. (Cambridge MA), Controlled drug delivery high molecular weight polyanhydrides.
  13. della Valle Francesco (Padova ITX) Romeo Aurelio (Rome ITX), Cross-linked esters of hyaluronic acid.
  14. Handley James R. (Amherst NY) Pahade Ravindra F. (Getzville NY), Cryogenic distillation with unbalanced heat pump.
  15. Hult Anders (Tby SEX) Malmstrom Eva (Bandhagen SEX) Johansson Mats (Stockholm SEX) Srensen Kent (Perstorp SEX), Dendritic macromolecule and process for preparation thereof.
  16. Casey Donald J. (Ridgefield CT) Jarrett Peter K. (Trumbull CT) Rosati Louis (Norwalk CT), Diblock and triblock copolymers.
  17. Nagase Yu (Sagamihara JPX) Aoyagi Takao (Sagamihara JPX) Miyata Fusae (Tokyo JPX), Drug release controlling material responsive to changes in temperature.
  18. Tang Robert H. (Murrysville PA) Chakrabarti Paritosh M. (Pittsburgh PA), Ethylenically unsaturated poly(alkyleneoxy) surfactants.
  19. Thir Basil (Grosse Ile MI) Newkirk David D. (Beaverton OR) Eisenstein Stephen E. (Oak Park MI) Langdon William K. (Grosse Ile MI), Fiber lubricants yielding low residues upon oxidation.
  20. Domb Abraham J. (Brookline MA) Langer Robert S. (Somerville MA), High molecular weight polyanhydride and preparation thereof.
  21. Langdon William K. (Grosse Ile MI), Hydroxyalkylamino glycosides and process of preparation.
  22. Winnik Francoise M. (Toronto CAX) Davidson Anthony R. (Toronto NY CAX) Lin John W-P. (Webster NY) Croucher Melvin D. (Oakville CAX), Inks containing block copolymer micelles.
  23. Tanaka Toyoichi (Wellesley MA) Ilmain Franck (St. Etienne FRX) Kokufuta Etsuo (Tsukuba MA JPX) Annaka Masahiko (Arlington MA), Interpenetrating-polymer network phase-transition gels.
  24. Anchor Michael J. (Northville MI) Hollis Rebecca P. (Flemington NJ) Drewno Gregory W. (Riverview MI), Latex composition employing specifically defined ethylene oxide/propylene oxide block copolymer surfactant and hydrophob.
  25. Slepian Marvin J. (Cleveland Heights OH), Method and apparatus for treatment of focal disease in hollow tubular organs and other tissue lumens.
  26. Nair Mridula (Penfield NY) Tan Julia S. (Rochester NY), Microgel drug delivery system.
  27. Langdon ; William K., Multi-block coupled polyoxyalkylene copolymer surfactants.
  28. Langdon William K. (Grosse Ile MI), Multi-block coupled polyoxyalkylene copolymer surfactants.
  29. Langdon William K. (Grosse Ile MI), Multi-block polyacetal copolymer surfactants.
  30. Langdon William K. (Grosse Ile MI), Non-ionic surface-active agents coupled with carbonates or carboxylic esters.
  31. Langdon William K. (Grosse Ile MI), Non-ionic surfactants containing acetal groups.
  32. Mller Beat (Marly CHX), Photocrosslinked polymers.
  33. Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  34. Yokoyama Masayuki (Matsudo JPX) Sakurai Yasuhisa (Tokyo JPX) Okano Teruo (Ichikawa JPX) Kataoka Kazunori (Kashiwa JPX), Physical trapping type polymeric micelle drug preparation.
  35. Zalipsky Samuel (Princeton NJ) Bolikal Durgadas (Edison NJ) Nathan Aruna (Piscataway NJ) Kohn Joachim B. (Highland Park NJ), Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon.
  36. Langdon William K. (Grosse Ile MI), Polyalkylene polyamine ether derivatives of polyoxyalkylene compounds.
  37. Domb Abraham J. (Brookline MA) Langer Robert S. (Somerville MA), Polyanhydrides with improved hydrolytic degradation properties.
  38. Yianni Yiannakis P. (Middlesex GBX) Wiles Martin C. (Middlesex GBX), Polymeric coating.
  39. Langdon William K. (Grosse Ile MI), Polyoxyalkylene polyamine detergent compositions.
  40. DeLuca Patrick P. (Lexington KY) Kanke Motoko (Fukuyama JPX) Sato Toyomi (Tokyo CA JPX) Schroeder Hans G. (Encinitas CA), Porous microspheres for drug delivery and methods for making same.
  41. Domb Abraham J. (Brookline MA) Langer Robert S. (Somerville MA), Preparation of anhydride copolymers.
  42. Langdon William K. (Grosse Ile MI), Process for preparing polyalkylene polyamine polyethers.
  43. Langdon William K. (Grosse Ile MI) Lundsted Lester G. (Grosse Ile MI), Surfactants derived from the reaction product of polyoxyalkylene polyols and polyglycidyl ethers and glycol-based antifr.
  44. Smith Carl R. (Bloomingdale NJ) Gaterud Mark T. (Annandale NJ) Jamiolkowski Dennis D. (Long Valley NJ) Newman ; Jr. Hugh D. (Chester NJ) Shalaby Shalaby W. (Lebanon NJ), Surgical fastener made from glycolide-rich polymer blends.

이 특허를 인용한 특허 (173)

  1. Sawhney,Amarpreet S., Adhesion barriers applicable by minimally invasive surgery and methods of use thereof.
  2. Sawhney, Amarpreet S.; Ransone, II, William H., Adhesive hydrogels for ophthalmic drug delivery.
  3. Ali,Mahfuza B.; Mitra,Sumita B.; Oxman,Joel D., Amide-functional polymers, compositions, and methods.
  4. Lele,Bhalchandra Shripad; Leroux,Jean Christophe, Amphiphilic diblock, triblock and star-block copolymers and their pharmaceutical compositions.
  5. Burke, Thomas H.; Cox, Brian J.; Fitz, Matthew J.; Ferrera, David, Aneurysm treatment device and method of use.
  6. Burke, Thomas H.; Cox, Brian J.; Fitz, Matthew J.; Ferrera, David, Aneurysm treatment device and method of use.
  7. Cox, Brian J., Aneurysm treatment device and method of use.
  8. Cox, Brian J., Aneurysm treatment device and method of use.
  9. Cox, Brian J., Aneurysm treatment device and method of use.
  10. Stupp, Samuel I.; Rajangam, Kanya; Hulvat, James F., Angiogenic heparin-binding epitopes, peptide amphiphiles, self-assembled compositions and related methods of use.
  11. Bavouzet, Bruno; Destarac, Mathias, Aqueous compositions comprising a chemical microgel associated with an aqueous polymer.
  12. Stopek, Joshua B.; Hadba, Ahmad Robert, Bioabsorbable surgical composition.
  13. Barman,Shikha P.; Schramm,Helice A.; Warner,Nicholas F., Biocompatible chemically crosslinked hydrogels for glucose sensing.
  14. Pathak,Chandrashekhar P.; Sawhney,Amarpreet S.; Edelman,Peter G., Biocompatible crosslinked polymers.
  15. Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Edelman, Peter G., Biocompatible crosslinked polymers with visualization agents.
  16. Pathak,Chandrashekhar P.; Sawhney,Amarpreet S.; Edelman,Peter G., Biocompatible crosslinked polymers with visualization agents.
  17. Sawhney, Amarpreet S.; Bennett, Steven; Edelman, Peter G., Biocompatible hydrogels made with small molecule precursors.
  18. Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Edelman, Peter G., Biocompatible polymers and hydrogels and methods of use.
  19. Shih, Chung; Zentner, Gaylen M., Biodegradable block copolymeric compositions for drug delivery.
  20. Shih, Chung; Zentner, Gaylen M., Biodegradable block copolymeric compositions for drug delivery.
  21. Shih, Chung; Zentner, Gaylen M., Biodegradable block copolymeric compositions for drug delivery.
  22. Elisseeff, Jennifer H., Biological adhesive.
  23. Stupp,Samuel I.; Guler,Mustafa O., Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof.
  24. Stupp, Samuel I.; Spoerke, Erik D.; Anthony, Shawn G.; Niece, Krista L., Charged peptide-amphiphile solutions and self-assembled peptide nanofiber networks formed therefrom.
  25. Sawhney, Amarpreet S., Composite hydrogel drug delivery systems.
  26. Stupp, Samuel I.; Beniash, Elia; Hartgerink, Jeffrey D., Composition and method for self-assembly and mineralization of peptide amphiphiles.
  27. Stupp, Samuel I.; Beniash, Elia; Hartgerink, Jeffrey D., Composition and method for self-assembly and mineralization of peptide-amphiphiles.
  28. Fuller, Gerald G.; Rappleye, C. Travis; Mandrusov, Evgenia, Compositions and methods for joining non-conjoined lumens.
  29. Gurtner, Geoffrey C.; Fuller, Gerald G.; Longaker, Michael T.; Rajadas, Jayakumar, Compositions and methods for joining non-conjoined lumens.
  30. Gurtner, Geoffrey C.; Fuller, Gerald G.; Longaker, Michael T.; Rajadas, Jayakumar; Saul, Gordon; Rappleye, C. Travis; Mandrusov, Evgenia, Compositions and methods for joining non-conjoined lumens.
  31. Gurtner, Geoffrey C.; Fuller, Gerald G.; Longaker, Michael T.; Rajadas, Jayakumar; Saul, Gordon; Rappleye, C. Travis; Mandrusov, Evgenia, Compositions and methods for joining non-conjoined lumens.
  32. Rappleye, C. Travis; Rimsa, Joseph; Hoffmann, Drew A., Compositions and methods for joining non-conjoined lumens.
  33. Rodeheaver, George; Katz, Adam, Compositions for treating biofilms and methods for using same.
  34. Rodeheaver, George; Katz, Adam, Compositions for treating biofilms and methods for using same.
  35. Rodeheaver, George; Katz, Adam, Compositions for treating biofilms and methods for using same.
  36. Rodeheaver, George; Katz, Adam, Compositions for treating biofilms and methods for using same.
  37. Havenstrite, Karen L.; McCray, Victor Wayne; Felkins, Brandon McNary; Ackermann, Douglas Michael; Smith, Garrett Cale; Cook, Paul A.; Luxon, Evan S.; McGibbon, Andrew A., Contact lens with a hydrophilic layer.
  38. Havenstrite, Karen L.; McCray, Victor Wayne; Felkins, Brandon McNary; Cook, Paul A., Contact lens with a hydrophilic layer.
  39. Ward, Robert S.; McCrea, Keith R.; Tian, Yuan; Parakka, James P., Control of polymer surface molecular architecture via amphipathic endgroups.
  40. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release antimicrobial compositions and methods for the treatment of OTIC disorders.
  41. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release antimicrobial compositions and methods for the treatment of otic disorders.
  42. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release antimicrobial compositions and methods for the treatment of otic disorders.
  43. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release antimicrobial compositions and methods for the treatment of otic disorders.
  44. Lichter, Jay; Lebel, Carl; Piu, Fabrice; Trammel, Andrew M., Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders.
  45. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Vollrath, Benedikt; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders.
  46. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Vollrath, Benedikt; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders.
  47. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Duron, Sergio G.; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release compositions for modulating free-radical induced damage and methods of use thereof.
  48. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Scaife, Michael Christopher; Vollrath, Benedikt; Duron, Sergio G.; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release compositions for modulating free-radical induced damage and methods of use thereof.
  49. Lichter, Jay; Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Lebel, Carl; Trammel, Andrew M.; Harris, Jeffrey P., Controlled release corticosteroid compositions and methods for the treatment of otic disorders.
  50. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Dellamary, Luis A.; Ye, Qiang; Lebel, Carl; Harris, Jeffrey P., Controlled release corticosteroid compositions and methods for the treatment of otic disorders.
  51. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release corticosteroid compositions and methods for the treatment of otic disorders.
  52. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release corticosteroid compositions and methods for the treatment of otic disorders.
  53. Lichter, Jay; Vollrath, Benedikt; Trammel, Andrew M.; Durón, Sergio G.; Piu, Fabrice; Dellamary, Luis A.; Ye, Qiang; Lebel, Carl; Scaife, Michael Christopher; Harris, Jeffrey P., Controlled release corticosteroid compositions and methods for the treatment of otic disorders.
  54. Lichter, Jay; Vollrath, Benedikt; Trammel, Andrew M.; Durón, Sergio G.; Piu, Fabrice; Dellamary, Luis A.; Ye, Qiang; Lebel, Carl; Scaife, Michael Christopher; Harris, Jeffrey P., Controlled release corticosteroid compositions and methods for the treatment of otic disorders.
  55. Ye, Qiang; Dellamary, Luis A., Controlled release corticosteroid compositions and methods for the treatment of otic disorders.
  56. Lichter, Jay; Lebel, Carl; Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Trammel, Andrew M.; Harris, Jeffrey P., Controlled-release CNS modulating compositions and methods for the treatment of otic disorders.
  57. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Scaife, Michael Christopher; Vollrath, Benedikt; Duron, Sergio G.; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled-release CNS modulating compositions and methods for the treatment of otic disorders.
  58. Pathak,Chandrashekhar P., Crosslinked albumin hydrogels.
  59. Asgarzadeh, Firouz; Costantino, Henry R., Crosslinked hydrogel copolymers.
  60. Pathak, Chandrashekhar P., Crosslinking agents and methods of use.
  61. Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Dreher, James H., Crosslinking methods and applications thereof.
  62. Shastri, Venkatram P., Degradable polymers from derivatized ring-opened epoxides.
  63. Yoo, James J.; Atala, Anthony; Binder, Kyle W.; Albanna, Mohammad Z.; Zhao, Weixin; Dice, Dennis; Xu, Tao, Delivery system.
  64. Schultz, Clyde L.; Schentag, Jerome J., Device and method for the delivery of drugs for the treatment of posterior segment disease.
  65. Fitz, Matthew; Tieu, Tai D.; O'Leary, Shawn, Device for occluding a lumen.
  66. Bennett, Steven L., Drug delivery device.
  67. Jarrett, Peter; El-Hayek, Rami; Sawhney, Amarpreet S.; Guedez, Sarah, Drug delivery systems and applications.
  68. Jarrett, Peter; Bassett, Michael; Blizzard, Charles D.; Sawhney, Amarpreet S., Drug delivery through hydrogel plugs.
  69. Sawhney, Amarpreet S.; Jarrett, Peter; Bassett, Michael; Blizzard, Charles, Drug delivery through hydrogel plugs.
  70. Goupil, Dennis W.; Chaouk, Hassan; Holland, Troy; Asfaw, Bruktawit T.; Goodrich, Stephen D.; Latini, Lucas, Embolic compositions.
  71. Goupil, Dennis W.; Chaouk, Hassan; Holland, Troy; Asfaw, Bruktawit T.; Goodrich, Stephen D.; Latini, Lucas, Embolic compositions.
  72. Goupil, Dennis W.; Chaouk, Hassan; Holland, Troy; Asfaw, Bruktawit T.; Goodrich, Stephen D.; Latini, Lucas, Embolic compositions.
  73. Constant, Michael; Garretson, Josh; Cruise, Gregory M., Embolic devices.
  74. Constant, Michael; Keeley, Edward Michael; Garretson, Joshua; Cruise, Gregory M., Embolic devices.
  75. Constant, Michael; Keeley, Edward Michael; Garretson, Joshua; Cruise, Gregory M.; Graczyk, Wendy, Embolic devices.
  76. Cruise, Gregory M.; Constant, Michael J.; Tran, Terrance, Embolization device constructed from expansile polymer.
  77. Cruise, Gregory M.; Constant, Michael J.; Tran, Terrance, Embolization device constructed from expansile polymer.
  78. Cruise, Gregory M.; Constant, Michael J.; Tran, Terrance, Embolization device constructed from expansile polymer.
  79. Cruise, Gregory M.; Constant, Michael; Tran, Terrance, Embolization device constructed from expansile polymer.
  80. Cruise, Gregory M.; Constant, Michael; Tran, Terrance; Gulachenski, Joseph, Embolization device constructed from expansile polymer.
  81. Cruise, Gregory M.; Constant, Michael; Tran, Terrance; Gulachenski, Joseph, Embolization device constructed from expansile polymer.
  82. Keeley, E. Michael; Cruise, Gregory M.; Constant, Michael J.; Warner, Sheila; Walker, Maricela, Embolization device constructed from expansile polymer.
  83. Kay,John F.; Eisch,John J., End-capped polymers and compositions containing such compounds.
  84. Kay,John F.; Eisch,John J., End-capped polymers and compositions containing such compounds.
  85. Cheng,Yu Ling; Lin,Hai Hui, Environment responsive gelling copolymer.
  86. Do, Hiep Q.; Davis, III, Richard Champion; Jones, Donald K.; Lorenzo, Juan A.; Mitelberg, Vladimir; Sherman, Darren R.; Vyakarnam, Murty, Foam matrix embolization device.
  87. Gong, Glen; Pai, Suresh Subraya; Sershen, Scott Robert, Fragmented hydrogels.
  88. Schultz, Clyde L., Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease.
  89. Schultz,Clyde L., Growth factor delivery systems for the healing of wounds and the prevention of inflammation and disease.
  90. Oxman, Joel D.; Nguyen, Mai T.; Mitra, Sumita B.; Bui, Hoa T.; Ma, Jingwen; Liu, Jie J.; Ali, Mahfuza B., Hardenable thermally responsive compositions.
  91. Koberstein, Jeffrey T.; Rengifo, Hernan R.; Grigoras, Cristian; Lancaster, Jeffrey, Heterobifunctional polymers and methods for layer-by-layer construction of multilayer films.
  92. Lancaster, Jeffrey; Koberstein, Jeffrey T.; Turro, Nicholas J., Heterotrifunctional molecules and methods for the synthesis of dendrimeric materials.
  93. Goupil,Dennis W.; Chaouk,Hassan; Holland,Troy; Asfaw,Bruktawit T.; Goodrich,Stephen D.; Latini,Lucas, Hydrogel biomedical articles.
  94. Sershen, Scott Robert; Pai, Suresh Subraya; Gong, Glen, Hydrogel compositions.
  95. Sershen, Scott Robert; Pai, Suresh Subraya; Gong, Glen, Hydrogel compositions.
  96. Sershen, Scott Robert; Pai, Suresh Subraya; Gong, Glen, Hydrogel compositions.
  97. Sershen, Scott Robert; Pai, Suresh Subraya; Gong, Glen, Hydrogel compositions.
  98. Engler, Amanda C.; Han, Wei; Maune, Hareem T.; Nelson, Alshakim; Vora, Ankit; Wojtecki, Rudy J.; Zhang, Mu San, Hydrogel compositions for direct-write printing applications.
  99. Won, Chee-Youb; Zhang, Yeli; Chu, Chih-Chang, Hydrogel entrapping therapeutic agent and stent with coating comprising this.
  100. Won, Chee-Youb; Zhang, Yeli; Chu, Chih-Chang, Hydrogel entrapping therapeutic agent and stent with coating comprising this.
  101. Won,Chee Youb; Zhang,Yeli; Chu,Chih Chang, Hydrogel entrapping therapeutic agent and stent with coating comprising this.
  102. Cruise, Gregory M.; Constant, Michael J.; Keeley, Edward Michael; Tran, Terrance T., Hydrogel filaments for biomedical uses.
  103. Sawhney, Amarpreet S.; Ransone, II, William H., Hydrogel polymeric compositions and methods.
  104. Sawhney, Amarpreet S.; Ransone, II, William H., Hydrogel polymeric compositions and methods.
  105. Sawhney, Amarpreet S.; Ransone, II, William H., Hydrogel polymeric compositions and methods.
  106. Won, Chee-Youb; Zhang, Yeli; Chu, Chih-Chang, Hydrogel-forming system with hydrophobic and hydrophilic components.
  107. Won, Chee-Youb; Zhang, Yeli; Chu, Chih-Chang, Hydrogel-forming system with hydrophobic and hydrophilic components.
  108. Pathak, Chandrashekhar P., Hydrogels for protein concentration.
  109. Bentley, Michael D.; Harris, J. Milton; Zhao, Xuan; Battle, III, William Dudley; Shen, Xiaoming, Hydrolytically degradable alkylene oxide based polymers.
  110. Cruise, Gregory M.; Constant, Michael J.; Keeley, Edward Michael; Tran, Terrance T., Implantation devices including hydrogel filaments.
  111. Campbell, Patrick; Sawhney, Amarpreet S., Implants and biodegradable fiducial markers.
  112. Campbell, Patrick; Sawhney, Amarpreet S., Implants and biodegradable tissue markers.
  113. Sawhney, Amarpreet S.; Spiridigliozzi, John, In situ materials formation.
  114. Sawhney, Amarpreet S., In situ polymerizable hydrogels.
  115. Asfaw, Bruktawit T.; Jackson, John C.; Lu, Zhihua; Zhai, Xiaowen; Shums, Sameer; Hirt, Thomas; Hu, Xianbo; René, Claude-Raymond, In-situ forming hydrogel wound dressings containing antimicrobial agents.
  116. Constant, Michael J.; Cruise, Gregory M.; Keeley, E. Michael; Berenstein, Alejandro, Injectable hydrogel filaments for biomedical uses.
  117. McHugh,Anthony J.; DesNoyer,Jessica R., Injectable system for controlled drug delivery.
  118. Khosravi, Farhad; Dreher, James, Materials formable in situ within a medical device.
  119. Khosravi, Farhad; Dreher, James, Materials formable in situ within a medical device.
  120. Kalinin,Iouri Tikhosovich; Davydov,Anatoly Borisovich; Leoniv,Boris Ivanovich; Solodkaya,Tatjana Igorevna; Khromov,Gennadiy Ljvovich; Bobkov,Iouri Gennadievich, Means for maintenance and/or correction of glucose concentration in blood.
  121. Jarrett, Peter; El Hayek, Rami; Bassett, Michael; Biggins, James, Method for applying flowable hydrogels to a cornea.
  122. Dalal, Paresh S.; Diamaano, Godofredo R.; Kulkarni, Shailesh C., Method for producing porous β-tricalcium phosphate granules.
  123. Dalal,Paresh S; Dimaano,Godofredo R; Toth,Carol A; Kulkarni,Shailesh C, Method of delivering a bioactive agent with porous β-tricalcium phosphate granules.
  124. Dalal,Paresh S; Dimaano,Godofredo R; Toth,Carol A; Kulkarni,Shailesh C, Method of forming bone with porous βtricalcium phosphate granules.
  125. Cohn,Daniel; Pines,Eli; Hotovely,Anna, Methods and compositions for reducing or eliminating post-surgical adhesion formation.
  126. Stupp,Samuel I.; Spoerke,Erik D.; Anthony,Shawn G.; Niece,Krista L., Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon.
  127. Sawhney,Amarpreet S., Methods for forming regional tissue adherent barriers and drug delivery systems.
  128. Pathak, Chandrashekhar P., Methods for preparation of platelet rich plasma.
  129. Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Lebel, Carl, Methods for the treatment of pediatric otic disorders.
  130. Pathak,Chandrashekhar P.; Barman,Shikha P.; Philbrook,C. Michael; Sawhney,Amarpreet S.; Coury,Arthur J.; Avila,Luis Z.; Kieras,Mark T., Multiblock biodegradable hydrogels for drug delivery and tissue treatment.
  131. Seo, Min-Hyo; Choi, In-Ja; Kong, Han-Uk, Negatively charged amphiphilic block copolymer as drug carrier.
  132. Chauhan, Anuj; Gulsen, Derya, Ophthalmic drug delivery system.
  133. Garigapati, Venkat R.; TenHuisen, Kevor S., Organophosphorous and multivalent metal compound compositions and methods.
  134. Garigapati, Venkat R.; Hess, Brian J.; Kimsey, Cassandra L.; Murphy, Matthew E., Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods.
  135. Fowers, Kirk Dee; Zentner, Gaylen M.; Shih, Chung; Piao, Ai-Zhi, PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water.
  136. Campbell, Patrick; Sawhney, Amarpreet S., Particulate implants and biodegradable fiducial markers.
  137. Hulvat, James F.; Guler, Mustafa O., Peptide amphiphiles having improved solubility and methods of using same.
  138. Shah, Ramille N.; Shah, Nirav A.; Stupp, Samuel I., Peptide-based scaffolds for cartilage regeneration and methods for their use.
  139. Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  140. Cruise, Gregory M.; Harris, Clayton G.; Constant, Michael J., Polymer filaments including pharmaceutical agents and delivering same.
  141. Cohn, Daniel; Stern, Theodor; Levi, Avraham, Polymeric compositions.
  142. Gupta, Kavita; Clark, Meredith R.; Kiser, Patrick F.; Jay, Julie I., Polymeric compositions and methods of making and using thereof.
  143. Constant, Michael; Cruise, Gregory M.; Chen, Samuel, Polymers.
  144. Gong, Glen; Pai, Suresh Subraya; Sershen, Scott Robert, Polysaccharide based hydrogels.
  145. Dalal, Paresh S.; Dimaano, Godofredo R.; Toth, Carol Ann; Kulkarni, Shailesh C., Porous β-tricalcium phosphate granules for regeneration of bone tissue.
  146. Seo,Min Hyo; Choi,In Ja; Cho,Young Hoon, Positively charged amphiphilic block copolymer as drug carrier and complex thereof with negatively charged drug.
  147. Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Dreher, James H., Protein crosslinkers, crosslinking methods and applications thereof.
  148. Pathak,Chandrashekhar P., Proteinaceous gels having visualization agents and methods of use thereof.
  149. Campbell, Patrick; Sawhney, Amarpreet S., Radioopaque covalently crosslinked hydrogel particle implants.
  150. Hossainy,Syed F. A., Remote activation of an implantable device.
  151. Cohn,Daniel; Sosnik,Alejandro, Responsive biomedical composites.
  152. Cohn, Daniel; Levi, Avraham, Reverse thermal gellation polymer of chain-extended optional polyester-terminated PEO-PPO-PEO.
  153. Stupp, Samuel I.; Donners, Jack J. J. M.; Silva, Gabriel A.; Behanna, Heather A.; Anthony, Shawn G., Self-assembling peptide amphiphiles and related methods for growth factor delivery.
  154. Stupp, Samuel I.; Donners, Jack J. J. M.; Silva, Gabriel A.; Behanna, Heather A.; Anthony, Shawn G., Self-assembling peptide amphiphiles and related methods for growth factor delivery.
  155. Stupp, Samuel I.; Donners, Jack J. J. M.; Silva, Gabriel A.; Behanna, Heather A.; Anthony, Shawn G., Self-assembling peptide amphiphiles and related methods for growth factor delivery.
  156. Stupp, Samuel I.; Hartgerink, Jeffrey D.; Beniash, Elia, Self-assembly and mineralization of peptide-amphiphile nanofibers.
  157. Stupp,Samuel I.; Hartgerink,Jeffrey D.; Beniash,Elia, Self-assembly and mineralization of peptide-amphiphile nanofibers.
  158. Stupp, Samuel I.; Hartgerink, Jeffrey D.; Beniash, Elia, Self-assembly of peptide-amphiphile nanofibers under physiological conditions.
  159. Stupp, Samuel I.; Hartgerink, Jeffrey D.; Beniash, Elia, Self-assembly of peptide-amphiphile nanofibers under physiological conditions.
  160. Stupp,Samuel I.; Hartgerink,Jeffrey D.; Beniash,Elia, Self-assembly of peptide-amphiphile nanofibers under physiological conditions.
  161. Tieu, Tai D.; Gulachenski, Joseph, Self-expanding prosthesis.
  162. Chaouk, Hassan; Asfaw, Bruktawit T.; Goupil, Dennis W., Spinal disc nucleus pulposus implant.
  163. Rapoport, Natalya; Pitt, William G., Stabilization and acoustic activation of polymeric micelles for drug delivery.
  164. Koller, Neal; Rodeheaver, George; Cassino, Roberto, Surface active agent compositions and methods for enhancing oxygenation, reducing bacteria and improving wound healing at a site of treatment.
  165. Zhang, Shuguang; Vauthey, Sylvain, Surfactant peptide nanostructures, and uses thereof.
  166. Stupp, Samuel I; Claussen, Randal C.; Rabatic, Bryan M., Synthesis and self-assembly of ABC triblock bola peptide amphiphiles.
  167. Hadba, Ahmad R.; Kennedy, John; Roby, Mark, Synthetic sealants.
  168. Lee, Doo Sung; Dayananda, Kasala; Kim, Bong Sup, Temperature and pH-sensitive block copolymer having excellent gel strength.
  169. Cheng,Yu Ling; May,Michael H.; Semple,John L.; Lin,Hai Hui, Thermally reversible implant and filler.
  170. Ding,Jiandong; Zhu,Wen; Wang,Biaobing; Zhang,Ying, Thermosensitive and biodegradable microgel and a method for the preparation thereof.
  171. Goupil, Dennis W.; Chaouk, Hassan; Holland, Troy; Asfaw, Bruktawit T.; Goodrich, Stephen D.; Latini, Lucas, Tissue bulking and coating compositions.
  172. Meier, Wolfgang; Sauer, Marc, Triblock copolymer hollow particles for agent delivery by permeability change.
  173. Ranger,Maxime; Leroux,Jean Christophe, Water-soluble stabilized self-assembled polyelectrolytes.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로