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Tocotrienols and tocotrienol-like compounds and methods for their use 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/355
  • C07D-311/22
  • C07D-311/72
출원번호 US-0182530 (1998-10-28)
발명자 / 주소
  • Lane Ronald H.
  • Qureshi Asaf A.
  • Salser Winston A.
출원인 / 주소
  • Lipogenics, Inc.
대리인 / 주소
    Lyon & Lyon LLP
인용정보 피인용 횟수 : 34  인용 특허 : 12

초록 ▼

The present invention relates to novel tocotrienols and tocotrienol-like compounds displaying biological activity. The tocotrienols and tocotrienol-like compounds of this invention may be conveniently obtained from biological sources or by chemical synthesis and may be used in pharmaceutical composi

대표청구항

[ What is claimed is:] [1.]1. A method for treating an inflammatory condition in a subject in need thereof comprising administering to said subject a composition comprising an effective amount of a tocotrienol or a mixture of tocotrienols.

이 특허에 인용된 특허 (12)

  1. Wang, Jonas C. T., Compositions and method for stabilization of anthralin comprising the addition of an oil soluble antioxidant and an anionic surfactant.
    상세보기
  2. Ohgaki Kazunari (Nara JPX) Katayama Takashi (Toyonaka JPX), Extractive separation method.
    상세보기
  3. Pearce Bradley C. (East Hampton CT), Farnesylated tetrahydro-naphthalenols as hypolipidemic agents.
    상세보기
  4. Pearce Bradley C. (East Hampton CT), Farnesylated tetrahydro-naphthalenols as hypolipidemic agents.
    상세보기
  5. Schmidt Douglass N. (Grosse Ile MI), Free-flowing, high density, fat soluble vitamin powders with improved stability.
    상세보기
  6. Marshall Lisa A. (Wayne PA) Steiner Kurt E. (Devon PA) Schiehser Guy A. (Malvern PA), Phospholipase A2 inhibitors.
    상세보기
  7. Pearce Bradley C. (East Hampton CT), Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia.
    상세보기
  8. Lane Ronald H. (Phoenix AZ) Qureshi Asaf A. (Madison WI) Salser Winston A. (Pacific Palisades CA), Tocotrienols and tocotrienol-like compounds and methods for their use.
    상세보기
  9. Lane Ronald H. ; Qureshi Asaf A. ; Salser Winston A., Tocotrienols and tocotrienol-like compounds and methods for their use.
    상세보기
  10. Lane Ronald H. ; Qureshi Asaf A. ; Salser Winston A., Tocotrienols and tocotrienol-like compounds and methods for their use.
    상세보기
  11. Wright John J. (North Guilford CT) Pearce Bradley C. (East Hampton CT) Parker Rex (Branford CT) Qureshi Asaf A. (Madison WI), Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders.
    상세보기
  12. Wright John J. (North Guilford CT) Pearce Bradley C. (East Hampton CT) Parker Rex (Branford CT) Qureshi Asaf A. (Madison WI), Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders.
    상세보기

이 특허를 인용한 특허 (34)

  1. Tan, Barrie, Annatto extract compositions, including geranyl geraniols and methods of use.
    상세보기
  2. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  3. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  4. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  5. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  6. Bromley, Philip J., Compositions containing non-polar compounds.
    상세보기
  7. Rich,Mel; Udell,Ronald G.; Hari,Siva P., Formulation and delivery method to enhance antioxidant potency of Vitamin E.
    상세보기
  8. Rich, Melvin Lee; Udell, Ronald G.; Hari, Siva P., Formulation and delivery method to enhance antioxidant potency of vitamin E.
    상세보기
  9. Rich, Melvin Lee; Udell, Ronald G.; Hari, Siva P., Formulation and delivery method to enhance antioxidant potency of vitamin E.
    상세보기
  10. Rich,Melvin; Udell,Ronald G.; Hari,Siva P., Formulation to enhance antioxidant potency of Vitamin E.
    상세보기
  11. Bromley, Philip J., Formulations of water-soluble derivatives of vitamin E and compositions containing same.
    상세보기
  12. Kim, Kwang-Soo; Park, Jun-Ho, Method for preparing pellets from rice husk and apparatus for removing odor using rice husk pellet bio-media.
    상세보기
  13. Hitz, William D.; Sauber, Thomas E.; Saunders, Court; Wolf, Fred R., Method of improving animal tissue quality by supplementing the animal diet with oleic acid and selected tocols.
    상세보기
  14. Sen, Chandan; Roy, Sashwati; Khanna, Savita; Rink, Cameron, Methods for treating burn and scar injury using tocotrienol compositions.
    상세보기
  15. McPeak, Patricia; Cheruvanky, Rukmini; Cherukuri, Reddy Sastry V.; Mazhar, Mohammed, Methods for treating joint inflammation, pain, and loss of mobility.
    상세보기
  16. Naguib, Yousry M. A.; Udell, Ronald G.; Passwater, Jr., Richard A.; Rich, Melvin Lee, Natural vitamin E compositions with superior antioxidant potency.
    상세보기
  17. Naguib,Yousry M. A.; Udell,Ronald G.; Passwater, Jr.,Richard A.; Rich,Melvin Lee, Natural vitamin E compositions with superior antioxidant potency.
    상세보기
  18. Naguib,Yousry M. A.; Udell,Ronald G.; Passwater, Jr.,Richard A.; Rich,Melvin Lee, Natural vitamin E compositions with superior antioxidant potency.
    상세보기
  19. Compadre, Cesar M.; Breen, Philip; Aykin-Burns, Nukhet; Hauer-Jensen, Martin; Enriquez, Raul G.; Kharade, Sujay; Malagon, Omar; Ordonez, Yadira; Ojeda, Edgar; Thakkar, Shraddha; Pineda, E. Nathalie; Jones, Darin, Preparation and use of a composition for prevention and mitigation of the effects of radiation.
    상세보기
  20. Wesson, Kieron E.; Hinman, Andrew W.; Jankowski, Orion D., Process for the production of alpha-tocotrienol and derivatives.
    상세보기
  21. Wesson, Kieron E.; Hinman, Andrew W.; Jankowski, Orion D., Process for the production of alpha-tocotrienol and derivatives.
    상세보기
  22. Wesson, Kieron W.; Hinman, Andrew W.; Jankowski, Orion D., Process for the production of alpha-tocotrienol and derivatives.
    상세보기
  23. Howard, Luke, Process of producing purified gamma- and delta-tocotrienols from tocol-rich oils or distillates.
    상세보기
  24. Miller, Guy M.; Hecht, Sidney M., Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers.
    상세보기
  25. Miller, Guy M.; Hecht, Sidney M.; Jankowski, Orion D.; Wesson, Kieron E.; Mollard, Paul, Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers.
    상세보기
  26. Miller, Guy M.; Hecht, Sidney M.; Jankowski, Orion D.; Wesson, Kieron E.; Mollard, Paul, Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers.
    상세보기
  27. Beinlich,Peggy; Boddupalli,Sekhar; Brown,Lesley A.; Dreon,Darlene M.; Flaim,Stephen; Miller,Guy; Phinney,Stephen D., Tocopherol enriched compositions and amelioration of inflammatory symptoms.
    상세보기
  28. Beinlich,Peggy; Boddupalli,Sekhar; Brown,Lesley A.; Dreon,Darlene M.; Flaim,Stephen; Miller,Guy; Phinney,Stephen D., Tocopherol enriched compositions for reducing IL6 levels.
    상세보기
  29. Miller, Guy M., Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones.
    상세보기
  30. Miller, Guy M., Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones.
    상세보기
  31. Miller, Guy M., Treatment of pervasive developmental disorders with redox-active therapeutics.
    상세보기
  32. Miller, Guy M.; Kheifets, Viktoria, Treatment of pervasive developmental disorders with redox-active therapeutics.
    상세보기
  33. Miller, Guy M.; Kheifets, Viktoria, Treatment of pervasive developmental disorders with redox-active therapeutics.
    상세보기
  34. Miller, Guy M.; Kheifets, Viktoria, Treatment of pervasive developmental disorders with redox-active therapeutics.
    상세보기

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