초록 ▼

A method for the reduction in the risk of transmitting a sexually transmitted disease--especially HIV and/or HSV--during sexual activity is provided. This method generally comprises the application of an effective amount of an inhibitory agent, preferably as a topical formulation, to the area or are

A method for the reduction in the risk of transmitting a sexually transmitted disease--especially HIV and/or HSV--during sexual activity is provided. This method generally comprises the application of an effective amount of an inhibitory agent, preferably as a topical formulation, to the area or areas of sexual contact prior to engaging in sexual activity. Inhibitory agents which are useful in the present invention include, for example, phosphorylated hesperidins, sulfonated hesperidins, polystyrene sulfonates, substituted benzenesulfonic acid formaldehyde co-polymers, H.sub.2 SO.sub.4 -modified mandelic acids, and the like. This method can be used by heterosexuals, homosexuals, and/or bisexuals engaged in a wide variety of sexual activities. In addition to anti-STD activity, these agents may also act as vaginal contraceptives; moreover, they generally have fewer side effects than conventional vaginal contraceptives (e.g., nonoxynol-9). For example, the compounds useful in this invention are generally not toxic to natural and beneficial vaginal flora and, thus, do not upset the local microbiological balance. The anti-STD method of the present invention has the added advantage that it can be implemented and controlled by either sexual party. Methods are also provided for reducing the risk of transmission of STD-causing organisms to health care providers and laboratory personnel (or other persons) who may come into contact with biological samples and specimens.

대표청구항 ▼

[ That which is claimed is:] [1.]1. A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two or more parties where the parties are not at risk of pregnancy, said method comprising applying an effective amount of a polystyrene

[ That which is claimed is:] [1.]1. A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two or more parties where the parties are not at risk of pregnancy, said method comprising applying an effective amount of a polystyrene sulfonate to an area of the body to be engaged in the sexual activity of at least one of the parties prior to the sexual activity and then engaging in the sexual activity, wherein the polystyrene sulfonate contains less than about 50 ppm dichloroethane and wherein the sexually transmitted disease is caused by gonococci, papilloma virus, or chlamydia.