초록 ▼

A method of forming an iridium oxide coating on a metal stent to achieve a firmattachment of a thin biocompatible coating of the iridium oxide such that the iridium oxide resists being dislodged from the stent upon expansion thereof in a vessel of the human body during implantation of the stent. The

A method of forming an iridium oxide coating on a metal stent to achieve a firmattachment of a thin biocompatible coating of the iridium oxide such that the iridium oxide resists being dislodged from the stent upon expansion thereof in a vessel of the human body during implantation of the stent. The method includes submerging the stent in a coating solution having an adequate concentration of iridium chloride in a suitable liquid vehicle, and subjecting the coating solution with stent immersed therein to combined heating and application of ultrasonic energy at a temperature and energy level and for a time interval sufficient to form a coating of iridium oxide of desired thickness and surface roughness on the underlying metal surface of the stent. An biomedical implant with such underlying metal surface of primarily passive structure and an iridium oxide coating as a biologically active surface firmly attached to the underlying metal surface has catalytic properties similar to the normal catalytic activity in the cell cycle of a human body to assist in reducing inflammation associated with contact of the biomedical implant with tissue and blood of the body.

대표청구항 ▼

[ What is claimed is:] [1.]1. A method of forming an iridium oxide coating on a stent to achieve a firm attachment of a thin biocompatible layer of the iridium oxide such that the iridium oxide resists being dislodged upon expansion of the stent in a vessel of the human body during implantation of t

[ What is claimed is:] [1.]1. A method of forming an iridium oxide coating on a stent to achieve a firm attachment of a thin biocompatible layer of the iridium oxide such that the iridium oxide resists being dislodged upon expansion of the stent in a vessel of the human body during implantation of the stent, said method comprising the steps of submerging the stent in a solution having an adequate concentration of an idium compound in a suitable liquid vehicle, and subjecting said solution with said stent immersed therein to combined heating and application of ultrasonic energy at a temperature and energy level and for a time interval sufficient to form a layer of iridium oxide of desired thickness on said stent.