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특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Rapid cryobaric sterilization and vaccine preparation

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61L-002/02    C12N-007/04   
미국특허분류(USC) 422/039 ; 422/001 ; 435/236 ; 436/543
출원번호 US-0165829 (1998-10-02)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Fish & Richardson P.C.
인용정보 피인용 횟수 : 53  인용 특허 : 14
초록
▼

The invention is based on the discovery that biological and non-biological materials can be sterilized, decontaminated, or disinfected by repeatedly cycling between relatively high and low pressures. Pressure cycling can be carried out at low, ambient, or elevated temperatures (e.g., from about -20.degree. C. to about 95.degree. C.). New methods based on this discovery can have applications in, for example, the preparation of vaccines, the sterilization of blood plasma or serum, the decontamination of military devices, and the disinfection of medical equ...

대표
청구항

[ What is claimed is:] [1.]1. A method for sterilizing a material comprising at least one desired protein, the method comprising:providing said material and, while maintaining the temperature of the material at 4.degree. C. or lower, increasing the pressure to an elevated pressure sufficient to sterilize the material but insufficient to irreversibly denatured the desired protein, thereby providing a sterilized material.

이 특허에 인용된 특허 (14)

  1. Shinitzky Meir (Rehovot ILX). Anti-tumor vaccines. USP1996125582831.
  2. Ting Edmund Y. (Kent WA) Raghavan Chidambaram (Kent WA). High pressure sterilization apparatus and method. USP1994055316745.
  3. Goodsir Stephen W. (Wayne PA) Ventura Dominic A. (Berlin NJ). Hypodermic syringe tray. USP1988064753345.
  4. Young Jack H. (Cambridge Springs PA) Halleck Frank E. (Erie PA). Load conditioning control method for steam sterilization. USP1979084164538.
  5. Carter Stephen D. (1895 Chartwell Trace Stone Mountain GA 30083). Method for the heat independent sterilization of microbially contaminated instruments. USP1997115686045.
  6. Liebert Richard T. (Ballston Spa NY) Brown Neil H. (Nassau NY) Pistolese John R. (Valatie NY). Method of terminal steam sterilization. USP1993055207983.
  7. Cheng Suzanne (El Cerrito CA). Methods and reagents for the polymerase chain reaction amplification of long DNA sequences. USP1996045512462.
  8. Hrinda Michael E. (Gwynedd Valley PA) D\Alisa Rose (Warrington PA) Tarr George C. (Jeffersonville PA). Methods for the inactivation of viruses in viral-contaminated pharmaceutical compositions. USP1994045300433.
  9. Laugharn ; Jr. James A. ; Hess Robert A. ; Tao Feng. Pressure-enhanced extraction and purification. USP2000096120985.
  10. Russell Alan J. (Wexford PA) Beckman Eric J. (Edgewood PA) Abderrahmare Diaf (Pittsburgh PA) Chaudhary Apurva K. (Pittsburgh PA). Process for the production of polyesters using enzymes and supercritical fluids. USP1995125478910.
  11. Wittwer Carl T. (Salt Lake City UT) Hillyard David R. (Salt Lake City UT) Ririe Kirk M. (Idaho Falls ID). Rapid thermal cycling device. USP1995105455175.
  12. Cox John Cooper,AUX ; Sparks Robert Edward ; Jacobs Irwin Clay ; Mason Norbert Simon. Spray dried vaccine preparation comprising aluminium adsorbed immunogens. USP1999055902565.
  13. Carter Stephen D. (Stone Mountain GA) Brazell James W. (Atlanta GA). Sterilization apparatus and method. USP1994025288462.
  14. Sewell Kenneth R. (Columbus OH). Sterilizing apparatus and method for sterilizing infectious waste materials. USP1993065217687.

이 특허를 인용한 특허 피인용횟수: 53

  1. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013108545857.
  2. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013108563012.
  3. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013108551506.
  4. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013128603494.
  5. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2013128603495.
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  7. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2013108545806.
  8. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2014058731842.
  9. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2013128613937.
  10. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2014078788212.
  11. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for delivery of frozen particle adhesives. USP2015069056047.
  12. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for delivery of frozen particle adhesives. USP2015069050251.
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  14. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for delivery of frozen particle adhesives. USP2015069060931.
  15. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2013048409376.
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  17. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2014058721583.
  18. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2014058725420.
  19. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2013108545855.
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