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Method for specific substance and molecule detection

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/543
출원번호 US-0346039 (1999-07-06)
발명자 / 주소
  • Starzl Timothy W.
  • Nunnery David W.
  • Robinson MaryBeth
  • Hanlin H. John
출원인 / 주소
  • Accelr8 Technology Corporation
대리인 / 주소
    Sheridan Ross, P.C.
인용정보 피인용 횟수 : 40  인용 특허 : 59

초록

A system for detecting a specific substance or analyte of interest is provided that includes one or more sensing units and an instrument for analyzing the sensing units. Each sensing unit preferably includes a substrate, an attachment layer and at least one capture layer that includes a ligand layer

대표청구항

[ What is claimed is:] [1.]1. A method for obtaining assay data, comprising:providing a test piece having a number of sensing units;controlling movement of said test piece;checking for identifying means on said test piece;discontinuing movement of said test piece based on said checking step;obtainin

이 특허에 인용된 특허 (59)

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  11. Tsay Yuh-Geng (San Jose CA) Calenoff Emanuel (Palo Alto CA) Gustafson Eric K. (Palo Alto CA) Trebino Rick (Livermore CA) Lee John (Cupertino CA), DNA probe diffraction assay and reagents.
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  24. Yasoshima Seikichi (Hino JPX) Koyama Mikio (Hino JPX) Okaniwa Kenichiro (Hino JPX), Immunoassay method for measuring immunological antigen in fluid sample.
  25. Nicoli David F. (448 Mills Way Goleta CA 93117) Elings Virgil B. (1155 Via Tranquilla Santa Barbara CA 93110), Immunoassay using optical interference detection.
  26. Giaever Ivar (Schenectady NY) Harrigan Dale (Tuskegee AL), Immunological detection device and method for its preparation.
  27. Backman Keith C. (Bedford MA) Munkholm Christiane (Salem MA), Ligand assay using interference modulation.
  28. Ofenloch-Hhnle Beatus (Munich DEX) Berger Michael (Penzberg DEX) Deger Arno (Seeshaupt DEX), Ligand trap useful in immunoassays of biotin or free biotin containing samples and improved immunoassays using these lig.
  29. Bergstrm Jan (Blinge SEX) Lfaas Stefan (Uppsala SEX) Johnsson Bo (Storvreta SEX), Matrix coating for sensing surfaces capable of selective biomolecular interactions, to be used in biosensor systems.
  30. Lambotte Paul P. (San Diego CA) Darter Robert C. (San Diego CA) Sarno Mark J. (Escondido CA), Membrane-based immunoassay method.
  31. Lange Gerald R. (Rochester NY), Method and apparatus for measuring optical retardation in transparent materials.
  32. Joseph Jose P. (Menlo Park CA) Itoh Kiminori (Tokyo JPX), Method and apparatus for optically detecting presence of immunological components.
  33. Stenberg Johan E. (Hedelundsragn 5 S-41743 Gteborg SEX) Stiblert Lars B. (vre Besvrsgatan 4 S-411 29 Gteborg SEX) Sandstrm Erland T. (Jungmansgaton 53 S-413 11 Gteborg SEX), Method and apparatus for studying surface properties.
  34. Kawaguchi Takeyuki (Hachioji JPX) Shiro Takashi (Hino JPX), Method and kit having layered device for detecting biological component by interference color.
  35. Nygren, B. Hakan; Sandstrom, E. Torbjorn; Stenberg, Johan E.; Stiblert, Lars B., Method and member for detecting and/or measuring the concentration of a chemical substance.
  36. Uzgiris Egidijus E. (Schenectady NY) Yates James R. (Schenectady NY), Method for forming 2-D crystals of proteins and macromolecules.
  37. Cielo Paolo (Montreal CAX) Cole Kenneth C. (St. Hubert CAX) Lamontagne Mario (Longueuil CAX), Method for on-line thickness monitoring of a transparent film.
  38. Yamada Takashi (Sagamihara JPX) Kaneko Nobutaka (Hachioji JPX) Tabara Takashi (Kokubunji JPX) Takahashi Takeo (Hachioji JPX), Method of effecting immunological analysis and apparatus for carrying out the same.
  39. Clark Brian R. (Mission Hills CA), Method of preparing derivatized polystyrene for spectroscopic studies.
  40. Walter Bert (South Bend IN), Multilayer analytical element having an impermeable radiation diffusing and blocking layer.
  41. Graves Howard (Albany CA), Noise controlled immunoassays.
  42. Spanier Richard F. (Chester NJ), Optical amplifier and method for amplifying optical polarization state change effects.
  43. Layton Derek G. (Cambridge GB2) Smith Alan M. (Royston GB2) Fisher John H. (Royston GB2) Pettigrew Robert M. (Cambridgeshire GB2) Petty-Saphon Satham (Saffron Waldon GB2), Optical assay technique.
  44. Koshiishi Kiyozou (Sagamihara JPX) Shinohara Etsuo (Hachioji JPX) Shimomura Masatsugu (Koganei JPX), Optical sensor.
  45. Lundstrm Kurt I. (Faergaregatan 10 S-582 52 Linkoeping SEX) Arwin Hans R. (Linkoeping SEX) Rieke Erwin (Seeheim-Jugenheim DEX) Sielaff Gnter (Bensheim DEX) Hennrich Norbert (Darmstadt DEX), Optical specific binding assay with reflection of polarized electromagnetic radiation.
  46. Walker Clifford G. (915 Weatherly Rd. Huntsville AL 35803), Passive laser accelerometer.
  47. Godfrey Robin E. (Welwyn GBX), Polymer-coated optical structures and methods of making and using the same.
  48. Yamori Tsunefumi (Kobe JPX) Yuasa Eiji (Amagasaki JPX) Hayashi Ryuzo (Higashiosaka JPX), Preparation of a selectively permeable membrane for an enzyme electrode.
  49. Berger Michael (Penzberg DEX) Deger Arno (Seeshaupt DEX) Maier Josef (Weilheim DEX), Preparation of a solid phase matrix containing a bound specific binding pair.
  50. Giese Roger W. (56 Oakland Ave. Quincy MA 02170), Process for applying multiple layers of a protein and a ligand extender to a surface and to the multiple-layer system.
  51. Wang Chao-Huei (Gurnee IL) Shah Dinesh O. (Vernon Hills IL), Process for producing magnetically responsive polymer particles and application thereof.
  52. Nygren Bo H. (Billdal SEX) Stenberg Johan E. (Gothenburg SEX), Process for providing articles with a biocompatible surface layer.
  53. Maurer Eberhard (Weilheim DEX) Deeg Rolf (Bernried DEX), Process for the production of a solid phase matrix coated with an immunologically active substance.
  54. Wang Chao-Huei J. (Gurnee IL) Shah Dinesh O. (Vernon Hills IL), Process to make magnetically responsive fluorescent polymer particles.
  55. Sano Takeshi (Albany CA) Cantor Charles R. (Berkeley CA), Recombinant streptavidin-protein chimeras useful for conjugation of molecules in the immune system.
  56. Reed Andrew M. (Arvada CO) Askill Ian N. (Arvada CO) Weber Willis W. (Morrison CO), Segmented polyether polyurethane.
  57. Bergstrm Jan (Blinge SEX) Lfas Stefan (Uppsala SEX) Johnsson Bo (Storvreta SEX), Sensing surfaces capable of selective biomolecular interactions, to be used in biosensor systems.
  58. Malmqvist Magnus (Upsala SEX) Karlsson Robert (Upsala SEX) Rnnberg Inger (Upsala SEX), Surface plasmon resonance sensor unit and its use in biosensor systems.
  59. Sleytr Uwe (10 Parhamerplatz A-1170 Vienna ATX) Sara Margit (90/2/24 Vorgartenstr A-1200 Vienna ATX), Use of structure with membrane having continuous pores.

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  13. Takeuchi,James M.; Song,Xuedong; Yang,Kaiyuan; Wei,Ning; Feaster,Shawn R., Metering technique for lateral flow assay devices.
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  17. Garimella,Viswanadham; Bernal,Yasmith, Method for attachment of silylated molecules to glass surfaces.
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  24. Cohen, David Samuel; Feaster, Shawn Ray, Microfluidic assay devices.
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  28. Withrow, III, Edward W.; Gorlach, Jorn, Portable apparatus for improved sample analysis.
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  36. Shamsheyeva, Alena; Howson, David C.; Metzger, Steven W., Rapid determination of microbial growth and antimicrobial susceptibility.
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  38. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  39. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  40. Kaylor,Rosann Marie; Yang,Difei; Atanassov,Zdravko Savov; Knotts,Michael Eugene, Systems to view and analyze the results from diffraction-based diagnostics.
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