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Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/00
  • C07K-005/00
  • C07K-007/00
  • A01N-038/17
출원번호 US-0302596 (1999-04-30)
발명자 / 주소
  • Coolidge Thomas R.
  • Ehlers Mario R. W.
출원인 / 주소
  • BioNebraska, Inc.
대리인 / 주소
    Zarley, McKee, Thomte, Voorhees & Sease
인용정보 피인용 횟수 : 92  인용 특허 : 3

초록

Individuals in need of treatment of ischemia-related reperfusion are treated, preferably intravenously, with a composition which includes a compound which binds to a receptor for the glucagon-like peptide-1. The invention relates to both the method and compositions for such treatment.

대표청구항 ▼

[ What is claimed is:] [1.]1. A method for amelioration of organ tissue injury caused by reperfusion of blood flow following a period of ischemia, which comprises:administering to an individual in need of such treatment an effective amount of a composition which includes a compound which binds to a

이 특허에 인용된 특허 (3)

  1. Tiholiz Ivan C. (18250 Roscoe Blvd. Northridge CA 91324), Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states.
    상세보기
  2. Mishra Lopa, Nucleic acids encoding proteins for early liver development.
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  3. Hoover Dennis J. ; Hulin Bernard ; Martin William H. ; Phillips Douglas ; Treadway Judith L., Substituted n-(indole-2-carbonyl)-glycinamides and derivatives as glycogen phosphorylase inhibitors.
    상세보기

이 특허를 인용한 특허 (92)

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  9. Rosen,Craig A.; Haseltine,William A.; Ruben,Steven M., Albumin fusion proteins.
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  10. Rosen,Craig A.; Haseltine,William A.; Ballance,David J.; Turner,Andrew J.; Ruben,Steven M., Albumin fusion proteins comprising GLP-1 polypeptides.
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