초록 ▼

A porous implantable prosthesis is loaded with a substance for subsequent application to biological tissues. A method according to loading the substance to the porous prosthesis is provided. A first fluid in combination with an added substance is applied to the porous prosthesis. During the applicat

A porous implantable prosthesis is loaded with a substance for subsequent application to biological tissues. A method according to loading the substance to the porous prosthesis is provided. A first fluid in combination with an added substance is applied to the porous prosthesis. During the application, the first fluid containing the substance is capable of penetrating into prosthesis pores. The first fluid is removed and a second fluid is applied to the prosthesis. The second fluid is not capable of significantly penetrating into the pores. Prior to the application of the second fluid, the prosthesis can be immersed in a third fluid and agitated via mechanical perturbation techniques so that any of the substance gathered on the surface of the body, after the application of the first fluid, is removed. The third fluid should not be capable of dissolving the substance.

대표청구항 ▼

[ What is claimed is:] [1.]1. A method of loading a substance into pores of an implantable prosthesis:providing a prosthesis having a surface and pores formed in said surface;applying a first fluid including a substance to said prosthesis, wherein during said act of applying, said first fluid penetr

[ What is claimed is:] [1.]1. A method of loading a substance into pores of an implantable prosthesis:providing a prosthesis having a surface and pores formed in said surface;applying a first fluid including a substance to said prosthesis, wherein during said act of applying, said first fluid penetrates into said pores;removing said first fluid from said prosthesis;applying a second fluid to said prosthesis to remove said substance from said surface of said prosthesis, wherein said second fluid has a contact angle greater than about 90.degree. so as to prevent said second fluid from significantly penetrating into said pores to remove said substance out from said pores during the application of said second fluid; andremoving said second fluid from said prosthesis, wherein said substance is deposited into said pores.