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Systems for electrophoretic transport and detection of analytes 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-027/26
출원번호 US-0134058 (1998-08-14)
발명자 / 주소
  • Kayyem Jon Faiz
  • Blackburn Gary
  • O'Connor Stephen D.
출원인 / 주소
  • Clinical Micro Sensors, Inc.
대리인 / 주소
    Flehr Hohbach Test Albritton & Herbert LLPTrecartin, Esq.
인용정보 피인용 횟수 : 77  인용 특허 : 47

초록

The invention relates to compositions and methods useful in the electrophoretic transport of target analytes to a detection electrode comprising a self-assembled monolayer (SAM). Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, eithe

대표청구항

[ We claim:] [1.]1. A method of detecting a target analyte in a sample comprising:a) placing said sample in an electric field between at least a first electrode and at least a second electrode sufficient to cause electrophoretic transport of said sample to the vicinity of a detection electrode compr

이 특허에 인용된 특허 (47)

  1. Pontius Brian W. (Palo Alto CA), Acceleration of nucleic acid hybridization.
  2. Heller Michael J. (Encinitas CA) Tu Eugene (San Diego CA), Active programmable electronic devices for molecular biological analysis and diagnostics.
  3. Stavrianopoulos Jannis (New York NY) Rabbani Elazar (New York NY) Abrams Samuel B. (New York NY) Wetmur James G. (Scardsdale NY), Analyte detection by means of energy transfer.
  4. Ribi Hans O. (Hillsborough CA) Guion Todd (San Mateo CA) Shafer Paul T. (Campbell CA), Analyte detection with multilayered bioelectronic conductivity sensors.
  5. Engelhardt Dean (New York NY) Rabbani Elazar (New York NY) Kline Stanley (Brooklyn NY) Stavrianopoulos Jannis G. (New York NY) Kirtikar Dollie (Elmhurst NY), Base moiety-labeled detectable nucleatide.
  6. Ribi Hans O. (Mateo CA), Biosensors employing electrical, optical and mechanical signals.
  7. Rabbani Elazar (New York NY) Engelhardt Dean L. (New York NY), Composition and method for the detection of the presence of a polynucleotide sequence of interest.
  8. Stavrianopoulos Jannis G. (New York NY), Compound and detectable molecules having an oligo- or polynucleotide with modifiable reactive group.
  9. Smith Lloyd M. (South Pasadena CA) Fung Steven (Palo Alto CA), Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for t.
  10. Stavrianopoulos Jannis G. (New York NY), Detectable molecules, method of preparation and use.
  11. Stavrianopoulos Jannis G. (New York NY), Detectable molecules, method of preparation and use.
  12. Stavrianopoulos Jannis G. (New York NY), Detectable molecules, method of preparation and use.
  13. Stavrianopoulos Jannis G. (New York NY), Detectable molecules, method preparation and use.
  14. Bannwarth Wilhelm (Upper Saddle River NJ) Muller Francis (Basel CHX), Detection of nucleic acids using a hairpin forming oligonucleotide primer and an energy transfer detection system.
  15. Hill Hugh A. O. (Oxford GB2) Libor Susan I. (Oxford GB2), Electrochemical assay for nucleic acids and nucleic acid probes.
  16. Krihak Michael ; Shieh Chan-Long, Electrochemical-based molecular detection apparatus and method.
  17. Ackley Donald E., Electrode configuration for matrix addressing of a molecular detection device.
  18. Brakel Christine L. (Brightwaters NY) Cook Alan F. (Cedar Groove NJ) Vuocolo Edmund (Bronx NY), End labeled nucleotide probe.
  19. Hashimoto Koji,JPX ; Ito Keiko,JPX ; Ishimori Yoshio,JPX ; Gotoh Masanori,JPX, Gene detection method.
  20. Englehardt Dean L. (New York NY) Rabbani Elazar (New York NY), Hybridization method for the detection of genetic material.
  21. Sargent Jeannine P. (22270 Kendle St. Cupertino CA 95014) Marks Jeff (4730 Cielo Vista Way San Jose CA 95129), Method and apparatus for determining the sequence of polynucleotides.
  22. Riviello John M. (2430 Paul Minnie Ave. Santa Cruz CA 95062) Wallace Gordon (35 Francis Street Wollongong NSW AUX) Sadik Omowunmi A. (c/o Dr PO Ogunbona ; PO Box 19 Keiraville NSW 2500 AUX), Method and apparatus for pulsed electrochemical detection using polymer electroactive electrodes.
  23. MacConnell William P. (Cardiff CA), Method and means for annealing complementary nucleic acid molecules at an accelerated rate.
  24. Stavrianopoulos Jannis G. (New York NY) Kirtikar Dollie (Elmhurst NY) Johnston Kenneth H. (New York NY) Thalenfeld Barbara E. (New York NY), Method and structures employing chemically-labelled polynucleotide probes.
  25. Okamoto Tadashi,JPX ; Tomida Yoshinori,JPX ; Yamamoto Nobuko,JPX ; Kawaguchi Masahiro,JPX ; Makino Keisuke,JPX ; Murakami Akira,JPX, Method for detecting a target nucleic acid by using an interaction of two kinds of reagents.
  26. Magda Darren (Cupertino CA) Sessler Jonathan L. (Austin TX) Iverson Brent L. (Austin TX) Sansom Petra I. (Austin TX) Crofts Shaun P. (Campbell CA), Method of expanded porphyrin-oligonucleotide conjugate synthesis.
  27. Stavrianopoulos Jannis G. (New York NY), Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group.
  28. Bieniarz Christopher (Highland Park IL) Huff Jeffrey B. (Park Ridge IL) Henrard Denis R. (Lake Forest IL), Methods of use of phenanthridium DNA intercalators for fluorescence detection.
  29. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Methods of using labeled nucleotides.
  30. Beattie Kenneth L., Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions.
  31. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Modified nucleotides and methods of preparing and using same.
  32. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Modified nucleotides and polynucleotides and complexes form therefrom.
  33. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Modified polynucleotides and methods of preparing same.
  34. Heller Michael J. (Encinitas CA) Tu Eugene (San Diego CA) Butler William F. (Carlsbad CA), Molecular biological diagnostic systems including electrodes.
  35. Bamdad Cynthia C. (Sharon MA) Sigal George B. (Arlington MA) Strominger Jack L. (Lexington MA) Whitesides George M. (Newton MA), Molecular recognition at surfaces derivatized with self-assembled monolayers.
  36. Eggers Mitchell D. (The Woodlands TX) Hogan Michael E. (The Woodlands TX) Beattie Kenneth L. (The Woodlands TX) Shumaker John (Houston TX) Ehrlich Daniel J. (Lexington MA) Hollis Mark (Concord MA), Multi-site detection apparatus.
  37. Ribi Hans O. (San Mateo CA) Guion Todd (Palo Alto CA) Shafer Paul T. (Burlingame CA), Multilayered bioelectronic sensors.
  38. Stavrianopoulos Jannis G. (New York NY), Nucleic acid hybridization assay and detectable molecules useful in such assay.
  39. Meade Thomas J. (Altadena CA) Kayyem Jon F. (Pasadena CA) Fraser Scott E. (Newport Beach CA), Nucleic acid mediated electron transfer.
  40. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  41. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  42. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  43. Fawcett Newton C. (Hattiesburg MS) Evans Jeffrey A. (Hattiesburg MS), Piezoelectric device for detection of polynucleotide hybridization.
  44. Bannwarth Wilhelm (Rheinfelden-Beuggen DEX) Mller Francis (Basel CHX), Ruthenium-lumazine energy transfer systems.
  45. Clark Michael G. (Buckinghamshire) Lee Rosemary A. (Middlesex) Lowe Christopher R. (Essex) Maynard Philip (Cambridgeshire) Sethi Rajinder S. (Northampton) Weir Donald J. (London GB2), Sensor devices.
  46. Beebe Thomas P. (Salt Lake City UT) Rabke-Clemmer Carol E. (Rochester NY), Thiol labeling of DNA for attachment to gold surfaces.
  47. Mikkelsen Susan R. (Montreal CAX) Millan Kelly M. (LaSalle CAX) Spurmanis Aleksandrs J. (Montreal CAX), Voltammetric sequence-selective sensor for target polynucleotide sequences.

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  2. Kayyem,Jon Faiz; O'Connor,Stephen D., AC/DC voltage apparatus for detection of nucleic acids.
  3. Wright, David Walter; Aiello, Dominic; Clark, Robert, Apparatus and methods for manipulating deformable fluid vessels.
  4. Wright, David Walter; Aiello, Dominic, Apparatus, devices, and methods for manipulating deformable fluid vessels.
  5. Braven, Helen; Keay, Russell, Assays and apparatus for detecting electrochemical active markers in an electric field.
  6. Blackburn, Gary; Creager, Stephen E.; Fraser, Scott; Irvine, Bruce D.; Meade, Thomas J.; O'Connor, Stephen J.; Terbrueggen, Robert H.; Vielmetter, Jost G.; Welch, Thomas W., Binding acceleration techniques for the detection of analytes.
  7. Mamine, Takayoshi; Yamamoto, Takuro, Bioassay method, bioassay device, and bioassay substrate.
  8. Shieh, Chan-Long; Foley, Barbara; Yu, Huinan; Choong, Vi-En, Biochannel assay for hybridization with biomaterial.
  9. Gau, Jen-Jr, Biological identification system with integrated sensor chip.
  10. Wright, David Walter; Aiello, Dominic; Kroehl, Peter; Kayyem, Jon Faiz; Gray, Darren Scott, Cartridge for performing assays in a closed sample preparation and reaction system.
  11. Ushiwata, Shigeharu; Takano, Shinji; Terashima, Hideaki; Matsunaga, Kenichi; Imamura, Ryuichi, Cutter with laser generator that irradiates cutting position on workpiece to facilitate alignment of blade with cutting position.
  12. Ushiwata, Shigeharu; Takano, Shinji; Terashima, Hideaki; Matsunaga, Kenichi; Imamura, Ryuichi, Cutter with laser generator that irradiates cutting position on workpiece to facilitate alignment of blade with cutting position.
  13. Ushiwata, Shigeharu; Takano, Shinji; Terashima, Hideaki; Matsunaga, Kenichi; Imamura, Ryuichi, Cutter with laser generator that irradiates cutting position on workpiece to facilitate alignment of blade with cutting position.
  14. Meade, Thomas J., Detection of analytes using reorganization energy.
  15. Meade, Thomas J., Detection of analytes using reorganization energy.
  16. Meade, Thomas J., Detection of analytes using reorganization energy.
  17. Meade, Thomas J., Detection of analytes using reorganization energy.
  18. Meade, Thomas J., Detection of analytes using reorganization energy.
  19. Meade,Thomas J., Detection of analytes using reorganization energy.
  20. Bamdad, Cynthia C.; Mucic, Robert C., Detection of target analytes using particles and electrodes.
  21. Duong,Hau H.; Blackburn,Gary; Kayyem,Jon F.; O'Connor,Stephen D.; Olsen,Gary T.; Pietri,Robert; Terbrueggen,Robert H., Devices and methods for biochip multiplexing.
  22. Wright, David Walter; Aiello, Dominic, Devices and methods for manipulating deformable fluid vessels.
  23. Maki, Wusi C., Direct electric biological agent detector.
  24. Roberts, Peter C.; Zenhausern, Frederic; Burdon, Jeremy W.; Sadler, Daniel J., Electro-chemical analysis device with integrated thermal sensor and method for monitoring a sample using the device.
  25. Brown, Bradley Adam; Martinez, Milena Iacobelli; Freeman-Cook, Lisa Lynn; Harvey, John Jay; Shaw, Christine J.; Al-Khouri, Anna Maria, Electrochemical detection of bacterial and/or fungal infections.
  26. Kayyem,Jon F.; O'Connor,Stephen D.; Gozin,Michael; Yu,Changjun; Meade,Thomas J., Electrodes linked via conductive oligomers to nucleic acids.
  27. Kayyem,Jon Faiz; O'Connor,Stephen D.; Gozin,Michael; Yu,Changjun, Electrodes linked via conductive oligomers to nucleic acids.
  28. Kayyem,Jon F.; O'Connor,Stephen D.; Gozin,Michael; Yu,Changjun; Meade,Thomas J., Electrodes linked via oligomers to nucleic acids.
  29. Pisharody, Sobha M.; Kunwar, Sandeep; Mathai, George T., Electronic detection of biological molecules using thin layers.
  30. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  31. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  32. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  33. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  34. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  35. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  36. O'Connor, Stephen D.; Kayyem, Jon Faiz, Electronics method for the detection of analytes.
  37. Segawa, Yuji; Kishii, Noriyuki, Hybridization detecting unit relying on dielectrophoresis and sensor chip provided with the detecting unit.
  38. Kayyem, Jon Faiz; Ford, Sean; Pamula, Vamsee K.; Srinivasan, Vijay; Corey, Scott; Murphy, Brian; Wright, David Walter; Aiello, Dominic, Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation.
  39. Richards, William L.; Ashby, Austin; Ketterer, Matthew; Marshall, Kevin; Harrison, Josh; Mette, Matthew; Richards, Paul; Showalter, Wayne; Cote, Jasmin; Halbert, Phillip C.; Bourgeois, Solene; Metzger, Steven W.; Hance, Ken; Mensack, Meghan; Michel, Carlos; Allers, Elke; Gamage, Dulini; Prisbrey, Landon; Gusyatin, Oleg; Shamsheyeva, Alena; Turng, Ben; Ghusson, Andrew; Reinhardt, Kurt, Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing.
  40. Richards, William L.; Ashby, Austin; Ketterer, Matthew; Marshall, Kevin; Harrison, Josh; Mette, Matthew; Richards, Paul; Showalter, Wayne; Cote, Jasmin; Halbert, Phillip C.; Bourgeois, Solene; Metzger, Steven W.; Hance, Ken; Mensack, Meghan; Michel, Carlos; Allers, Elke; Gamage, Dulini; Prisbrey, Landon; Gusyatin, Oleg; Shamsheyeva, Alena; Turng, Ben; Ghusson, Andrew; Reinhardt, Kurt, Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing.
  41. Corey, Scott; Murphy, Brian; Schneider, Eric; Wright, David Walter; Aiello, Dominic; Fish, Andrew; Srinivasan, Jay; Maltezos, George, Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system.
  42. Kayyem, Jon Faiz; Srinivasan, Jayashankar; Ford, Sean, Integrated multiplex target analysis.
  43. Ward, Jonathan W.; Meinhold, Mitchell; Bertin, Claude L.; Schlatka, Benjamin; Segal, Brent M.; Ruckes, Thomas, Light emitters using nanotubes and methods of making same.
  44. Prisbrey, Landon; Blackmore, Elise; Hance, Kenneth R.; Metzger, Steven W.; Marshall, Kevin, Membrane-assisted purification.
  45. Choong, Vi-En; Li, Changming; Shi, Song; Maracas, George, Method for enhanced bio-conjugation events.
  46. Barlow,Carrolee; Bhatia,Sangeeta N.; Ozkan,Mihrimah; Esener,Sadik C., Microelectronic arrays for cell-based functional genomics/high throughput phenotyping by electrokinetic assembly.
  47. Kayyem, Jon Faiz, Microfluidic systems in the electrochemical detection of target analytes.
  48. Mobley,J. Kenneth; Kuhr,Werner, Molecular memory.
  49. Kuhr,Werner G.; Gallo,Antonio R., Molecular memory devices and methods.
  50. Misra, Veena; Shrivastava, Ritu; Chen, Zhong; Mathur, Guru, Molecular memory devices including solid-state dielectric layers and related methods.
  51. Meade, Thomas J; Kayyem, Jon Faiz; Fraser, Scott E, Nucleic acid mediated electron transfer.
  52. Braven, Helen; Keay, Russell, Nucleic acid probes, their synthesis and use.
  53. Kuhr, Werner G.; Shrivastava, Ritu; Gallo, Antonio R.; Mobley, Kenneth J.; DeBolske, Tom, Processing systems and methods for molecular memory.
  54. Li, Changming; Sawyer, Jaymie Robin; Choong, Vi-En; Maracas, George; Zhang, Peiming, Protein and peptide sensors using electrical detection methods.
  55. Kahlman, Josephus Arnoldus Henricus Maria; Thilwind, Rachel Estelle; Prins, Menno Willem Jose; Megens, Mischa; Wimberger-Friedl, Reinhold, Rapid and sensitive biosensing.
  56. Metzger, Steven W.; Hance, Kenneth Robert, Rapid cell purification systems.
  57. Metzger, Steven W.; Hance, Kenneth Robert, Rapid cell purification systems.
  58. Metzger, Steven W.; Hance, Kenneth Robert, Rapid cell purification systems.
  59. Shamsheyeva, Alena; Howson, David C.; Metzger, Steven W., Rapid determination of microbial growth and antimicrobial susceptibility.
  60. Metzger, Steven W.; Howson, David C.; Goldberg, David A.; Buttry, Daniel A., Rapid microbial detection and antimicrobial susceptibility testing.
  61. Metzger,Steven W.; Howson,David C.; Goldberg,David A.; Buttry,Daniel A., Rapid microbial detection and antimicrobial susceptibility testing.
  62. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  63. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  64. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  65. Goldberg, David A.; Howson, David C.; Metzger, Steven W.; Buttry, Daniel A.; Saavedra, Steven Scott, Sensitive and rapid determination of antimicrobial susceptibility.
  66. Dayagi, Yohai Y.; Dayan, Lev; Shalom, Moshe, Sensitive and selective method and device for the detection of trace amounts of a substance.
  67. Dayagi,Yohai Y.; Dayan,Lev; Shalom,Moshe, Sensitive and selective method and device for the detection of trace amounts of a substance.
  68. Dayan, Lev; Dayagi, Yohai Y.; Shalom, Moshe, Sensitive and selective method and device for the detection of trace amounts of a substance.
  69. Segal, Brent M.; Rueckes, Thomas; Vogeli, Bernhard; Brock, Darren K.; Jaiprakash, Venkatachalam C.; Bertin, Claude L., Sensor platform using a horizontally oriented nanotube element.
  70. Segal, Brent M.; Rueckes, Thomas; Vogeli, Bernhard; Brock, Darren; Jaiprakash, Venkatachalam C.; Bertin, Claude L., Sensor platform using a horizontally oriented nanotube element.
  71. Segal,Brent M.; Rueckes,Thomas; Vogeli,Bernhard; Brock,Darren; Jaiprakash,Venkatachalam C.; Bertin,Claude L., Sensor platform using a non-horizontally oriented nanotube element.
  72. Umek, Robert M.; Blackburn, Gary; Irvine, Bruce D.; Terbrueggen, Robert; Yu, Changjun; Vielmetter, Jost G., Signal detection techniques for the detection of analytes.
  73. Monbouquette, Harold G.; Garcia Garibay, Miguel, Surface nanopatterning.
  74. Gallo, Antonio R.; Kuhr, Werner G., Systems, tools and methods for production of molecular memory.
  75. Kayyem, Jon Faiz, Use of microfluidic systems in the electrochemical detection of target analytes.
  76. Kayyem, Jon Faiz, Use of microfluidic systems in the electrochemical detection of target analytes.
  77. Kayyem, Jon Faiz, Use of microfluidic systems in the electrochemical detection of target analytes.
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