초록 ▼

A medical graft, such as a vascular graft, made of a fabric containing an inorganic antimicrobial agent. The fabric has a coating material with the inorganic antimicrobial agent bonded to it, the agent preferably being a zeolite. The fabric can be porous so as to permit tissue to grow on it with the

A medical graft, such as a vascular graft, made of a fabric containing an inorganic antimicrobial agent. The fabric has a coating material with the inorganic antimicrobial agent bonded to it, the agent preferably being a zeolite. The fabric can be porous so as to permit tissue to grow on it with the fabric pores providing attachment sites for the tissue. Alternatively, the fabric can be coated with a tissue biocompatible material, such as collagen. A porous fabric applicable for the graft, and for other medical uses, and a method of manufacturing the porous fabric having a coating thereon to which is bonded an antimicrobial agent, such as a zeolite, also is provided. The fabric is antimicrobial, remains pliable, and is also porous.

대표청구항 ▼

[ We claim:] [1.]1. A porous, flexible, medical graft comprising:(a) fabric material in a generally tubular shape; and(b) ceramic particles bound to the fabric material, the particles comprising antimicrobial metal cations ion-exchanged thereon, wherein some or all of the ceramic particles are exter

[ We claim:] [1.]1. A porous, flexible, medical graft comprising:(a) fabric material in a generally tubular shape; and(b) ceramic particles bound to the fabric material, the particles comprising antimicrobial metal cations ion-exchanged thereon, wherein some or all of the ceramic particles are exteriorly exposed to permit entry into the particles of water and cations, thereby effecting an ion exchange reaction, which releases antibiotic cations from the ceramic particles in an antimicrobially effective amount.