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Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/543
출원번호 US-0249321 (1999-02-11)
발명자 / 주소
  • Nowakowski Mark R.
  • Buechler Kenneth F.
  • Anderson Richard R.
  • Valkirs Gunars E.
출원인 / 주소
  • Biosite Diagnostics, Inc.
대리인 / 주소
    Foley & Lardner
인용정보 피인용 횟수 : 44  인용 특허 : 36

초록

Devices for use in heterogeneous ligand-receptor assays, having a porous member in contact with a nonabsorbent textured surface, where the surface texturing is such that a capillary network is formed when in fluid communication with the porous member. More particularly, these devices comprise:

대표청구항 ▼

[ What is claimed is:] [1.]1. A device for performing a heterogeneous assay, comprising:(a) a porous member having (i) a means for physically entrapping at least one target ligand on said porous member from a fluid sample in at least one zone and (ii) a means for detecting the presence or amount of

이 특허에 인용된 특허 (36)

  1. Deutsch Alice (New York NY) Brandwein Harvey (Port Washington NY) Platt Herbert (Great Neck NY) Hunter Dianne M. (New Rochelle NY) Dubitsky Andrew (Amityville NY) Durham Susan M. (Westbury NY), Antigen assay method and kit.
    상세보기
  2. Guire Patrick E. (Eden Prairie MN) Swanson Melvin J. (Carver MN), Chemical analysis apparatus and method.
    상세보기
  3. Houts Thomas M. (Mountain View CA) Ullman Edwin F. (Atherton CA), Chromatographic devices having modified edges.
    상세보기
  4. Litman David (Los Altos CA) Zuk Robert (Menlo Park CA) Rowley Gerald (San Jose CA), Chromatographic strip having non-compressed edges.
    상세보기
  5. Weng Litai (Mountain View CA) Calderhead David (Menlo Park CA) Khanna Pyare (San Jose CA) Ullman Edwin F. (Atherton CA), Concentrating immunochemical test device and method.
    상세보기
  6. Tom Henry K. (La Honda CA) Rowley Gerald L. (Cupertino CA), Concentrating zone method in heterogeneous immunoassays.
    상세보기
  7. Katz David H. (La Jolla CA) Cooper Steven W. (San Diego CA) Lee Theodore T. (San Diego CA) Chang Shung-Ho (Encinitas CA), Detection of HCG with solid phase support having avidin coating.
    상세보기
  8. Sheiman Mark I. (Miami FL) Giegel Joseph L. (Miami FL) Brotherton Mary (Miami FL), Detection of serum antibody and surface antigen by radial partition immunoassay.
    상세보기
  9. Buechler Kenneth F. (San Diego CA), Diagnostic devices for the controlled movement of reagents without membranes.
    상세보기
  10. Parikh Indu (Chapel Hill NC) Cuatrecasas Pedro (Chapel Hill NC), Diagnostic reagent.
    상세보기
  11. Liotta Lance A. (5621 Sonoma Rd. Bethesda MD 20817), Enzyme immunoassay with two-zoned device having bound antigens.
    상세보기
  12. Lenhoff Howard M. (Costa Mesa CA) Ngo That T. (Irvine CA), Heterogeneous immunoassay method.
    상세보기
  13. Frickey Paul H. (Rochester NY) Sanford Karl J. (Rochester NY) Dappen Glen M. (Webster NY) Thunberg Allen L. (Pittsford NY) Sundberg Michael W. (Penfield NY) Danielson Susan J. (Rochester NY), Heterogeneous immunoassay utilizing horizontal separation in an analytical element.
    상세보기
  14. Root David M. (Bedford MA) Cole Francis X. (Stow MA), Immunoassay with membrane immobilized antibody.
    상세보기
  15. Grubb Anders O. (Lund SEX) Glad Ulla C. (Malmo SEX), Immunoassay with test strip having antibodies bound thereto.
    상세보기
  16. Zuk Robert F. (Menlo Park CA) Litman David J. (Mountain View CA), Immunochromatographic assay with support having bound “MIP”and second enzyme.
    상세보기
  17. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.
    상세보기
  18. Gefter Malcolm L. (Newton MA), Ligand assay with one or two particulate reagents and filter.
    상세보기
  19. Columbus Richard L. (Rochester NY), Liquid transport device and method.
    상세보기
  20. Columbus Richard L. (Rochester NY), Liquid transport device containing means for delaying capillary flow.
    상세보기
  21. Valkirs Gunars E. (San Marcos CA) Owen Newton C. (Encinitas CA) Levinson Philip A. (San Diego CA), Method and apparatus for immunoassays.
    상세보기
  22. Valkirs Gunars E. (San Marcos CA) Owen Newton C. (Encinitas CA) Levinson Philip A. (San Diego CA), Method and apparatus for immunoassays.
    상세보기
  23. Kawai ; Shoji ; Yamada ; Shigeki ; Kishimoto ; Shinichi, Method and device for testing liquids.
    상세보기
  24. Columbus Richard L. (Rochester NY), Multi-zoned reaction vessel having pressure-actuatable control means between zones.
    상세보기
  25. Alcock Susan,GBX ; White Stephen,GBX ; Turner Anthony,GBX ; Setford Steven,GBX ; Tothill Ibtisam,GBX ; Dicks Jon,GBX ; Stephens Sarah,GBX ; Hall Jennifer,GBX ; Warner Phillip,GBX, Printed fluid transport devices.
    상세보기
  26. Swanson Melvin J. (Carver MN) Guire Patrick E. (Eden Prairie MN), Quantitative analysis apparatus and method.
    상세보기
  27. Ullman Edwin F. (Atherton CA), Sample collector and assay device and method for its use.
    상세보기
  28. Giegel Joseph L. (Miami FL) Brotherton Mary M. (Miami FL), Solid phase system for ligand assay.
    상세보기
  29. Giegel Joseph L. (Miami FL) Brotherton Mary M. (Miami FL), Solid phase system for ligand assay.
    상세보기
  30. Giegel Joseph L. (Miami FL) Brotherton Mary M. (Miami FL), Solid phase system for ligand assay.
    상세보기
  31. Cole Francis X. (Stowe MA) Edwards James H. (Winchester MA) Hendrick Clifford L. (Boxboro MA) VanVoorhis Deborah M. (Watertown MA), Test device.
    상세보기
  32. Deutsch ; Marshall E. ; Mead ; Louis W., Test device.
    상세보기
  33. Deutsch Marshall E. (Sudbury MA) Mead Louis W. (Lexington MA), Test device and method for its use.
    상세보기
  34. Deutsch Marshall E. (Sudbury MA) Mead Louis W. (Lexington MA), Test device and method for its use.
    상세보기
  35. Buechler Kenneth F. (Santee CA) Valkirs Gunars E. (Escondido CA) Anderson Richard R. (Encinitas CA), Threshold ligand-receptor assay.
    상세보기
  36. Buechler Kenneth F. (Santee CA) Valkirs Gunars E. (Escondido CA) Anderson Richard R. (Encinitas CA), Threshold ligand-receptor assay.
    상세보기

이 특허를 인용한 특허 (44)

  1. Redmond, Gareth; Kewell, Adrian; Kruger, Jan; Von Papen, Georg, Analysis system.
    상세보기
  2. Bachand,Steven S., Binding assay device with non-absorbent carrier material.
    상세보기
  3. Bachand,Steven S., Binding assay device with non-absorbent carrier material.
    상세보기
  4. Cohen, David; Kaylor, Rosann; Sayre, Curtis, Biomolecule diagnostic device.
    상세보기
  5. Sayre, Curtis; Cohen, David; Kaylor, Rosann, Biomolecule diagnostic devices.
    상세보기
  6. Sayre,Curtis; Cohen,David; Kaylor,Rosann, Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices.
    상세보기
  7. Peltier, Eric, Device for depositing cells on an analytical plate.
    상세보기
  8. Liang, Greg; Kirby, Kevin J., Device for handling and analysis of a biological sample.
    상세보기
  9. Rhode, Heidrun; Kreusch, Stefan; Endmann, Helga; Händel, Michael; Sammler, Günther; Zimmermann, Edith, Device for receiving, treating, and storing small volume samples.
    상세보기
  10. Buechler, Kenneth F., Diagnostic devices and apparatus for the controlled movement of reagents without membranes.
    상세보기
  11. Cohen,David; Kaylor,Rosann, Diffraction-based diagnostic devices.
    상세보기
  12. Cohen,David; Kaylor,Rosann, Diffraction-based diagnostic devices.
    상세보기
  13. Cohen,David; Kaylor,Rosann, Diffraction-based diagnostic devices.
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  14. Kaylor,Rosann; Cohen,David; Sayre,Curtis, Diffraction-based diagnostic devices.
    상세보기
  15. Sayre,Curtis; Kaylor,Rosann; Cohen,David, Diffraction-based diagnostic devices.
    상세보기
  16. Esfandiari, Javanbakhsh, Dual path immunoassay device.
    상세보기
  17. Esfandiari, Javanbakhsh, Dual path immunoassay device.
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  18. Esfandiari, Javanbakhsh, Dual path immunoassay device.
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  19. Esfandiari, Javanbakhsh, Dual path immunoassay device.
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  20. Esfandiari, Javanbakhsh, Dual path immunoassay device.
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  21. Esfandiari,Javanbakhsh, Dual path immunoassay device.
    상세보기
  22. Boga,Rameshbabu; Chidebelu Eze,Chibueze Obinna; Kaylor,Rosann M.; Song,Xuedong, Enhanced diffraction-based biosensor devices.
    상세보기
  23. Flavin, Diarmuid; Moynihan, Shane; Kruger, Jan; Walsh, Jim, Flow control device for assays.
    상세보기
  24. Gokhan, Cem, Hybrid phase lateral flow assay.
    상세보기
  25. Esfandiari, Javanbakhsh, Immunoassay methods utilizing trapping conjugate.
    상세보기
  26. Esfandiari, Javanbakhsh, Immunoassay utilizing trapping conjugate.
    상세보기
  27. McDevitt, John T.; Ballard, Karri L.; Floriano, Pierre N.; Christodoulides, Nick J.; Neikirk, Dean; Anslyn, Eric; Shear, Jason, Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems.
    상세보기
  28. Owens, Mitchell, Lateral flow test strip.
    상세보기
  29. Masters, Brett P., Method and apparatus for analyzing bioprocess fluids.
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  30. Masters, Brett P.; Miller, Michael; Gulati, Vishal K.; Lundstrom, Mark; Srivastava, Alok; Wang, Wayne U., Method and apparatus for detecting estradiol and metabolites thereof using an acoustic device.
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  31. Miller,Michael F.; Masters,Brett P.; Lundstrom,Mark E., Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles.
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  32. Srivastava, Alok; Wang, Wayne U.; Miller, Michael; Masters, Brett P.; Lundstrom, Mark, Method and apparatus for detection of analyte using an acoustic device.
    상세보기
  33. Miller, Michael; Masters, Brett P.; Lundstrom, Mark; Srivastava, Alok; Wang, Wayne U., Method and apparatus for therapeutic drug monitoring using an acoustic device.
    상세보기
  34. Cohen, David; Kaylor, Rosann; Sayre, Curtis, Method for producing biomolecule diagnostic devices.
    상세보기
  35. Sauer Budge, Alexis F.; Fitch, Eric; Masters, Brett P.; Miller, Michael; Lundstrom, Mark, Methods and apparatus for detecting bacteria using an acoustic device.
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  36. Masters, Brett P.; Miller, Michael; Lundstrom, Mark, Methods and apparatus for detecting cardiac injury markers using an acoustic device.
    상세보기
  37. Sauer Budge, Alexis F.; Masters, Brett P.; Miller, Michael; Lundstrom, Mark, Methods and apparatus for detecting viruses using an acoustic device.
    상세보기
  38. McDevitt, John T.; Christodoulides, Nicolaos J.; Floriano, Pierre N.; Douglas, Gary N.; Rogers, Patrick E., Methods and compositions related to determination and use of white blood cell counts.
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  39. Buechler, Kenneth F.; Anderberg, Joseph M; McPherson, Paul H., Methods for monitoring the status of assays and immunoassays.
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  40. Dubrow, Robert S.; Kennedy, Colin B.; Nagle, Robert; Chazan, David; Lee, Ernest C. W.; Gandhi, Khushroo; Chow, Calvin Y. H., Microfluidic devices and systems incorporating cover layers.
    상세보기
  41. Ohman, Per Ove; Lindstrom, Tomas; Mendel Hartvig, Ib, Optical assay system.
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  42. Liang, Greg; Liang, Yahong, Rapid test apparatus.
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  43. Esfandiari, Javanbakhsh, Reduced step dual path immunoassay device and method.
    상세보기
  44. Arenas, Jaime E.; Choi, Hyun-Goo; Dickerson, William Matthew; Hembree, Sarah Beth; Madison, Lara Louise; Masters, Brett P.; Miller, Michael F.; Wang, Wayne U., Reusable detection surfaces and methods of using same.
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