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pH-modified biocompatible monomer and polymer compositions 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C09J-101/00
출원번호 US-0588621 (2000-06-07)
발명자 / 주소
  • Clark Jeffrey G.
  • Leung Jeffrey C.
출원인 / 주소
  • Closure Medical Corporation
대리인 / 주소
    Oliff & Berridge, PLC
인용정보 피인용 횟수 : 39  인용 특허 : 50

초록

The pH-modified monomer and polymer compositions are useful as biomedical and surgical adhesives, sealants, implants and bioactive agent release carriers or matrices. They comprise a monomer or polymer; and an effective amount of an acidic or basic pH modifier effective to modify the pH of an immedi

대표청구항

[ We claim:] [1.]1. A method comprising:(a) applying to an in vivo surface a biocompatible composition comprising:(1) at least one monomer which forms a polymer in situ at a physiologic pH; and(2) an effective amount of at least one biocompatible pH modifier to modify the pH of an immediate in vivo

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  1. Dombroski John R. (Kingsport TN) Weemes Doyle A. (Greeneville TN), 2-Cyanoacrylate adhesive composition.
  2. Hirakawa Eisuke (Osaka JPX), a 상세보기
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  • Coquard Jean (Grezieu-La Varenne FR) Sedivy Pierre (Sceaux FR) Ruaud Michel (Ternay FR) Verrier Jean (Boulogne-sur-Seine FR), Bioresorbable surgical articles.
  • Sagae Kyuta (Fuji JPX) Takemura Naoto (Fujinomiya JPX) Sugiyama Yoshiaki (Numazu JPX) Tanabe Susumu (Fujinomiya JPX), Catheter for repair of blood vessel.
  • Raju Katari S. (Jacksonville FL), Chain-stopped unsaturated polyester resins.
  • Marshall Joseph W. (1617 Beverly Blvd. Los Angeles CA 90026), Composition with selectively active modifier and method.
  • Overhults Wendell C. (East Brunswick NJ), Cross-linked cyanoacrylate adhesive compositions.
  • Lim Richard (Livingston NJ) Leone Robert (Fanwood NJ), Denture adhesive composition.
  • Kensey Kenneth (Hinsdale IL), Device for sealing percutaneous puncture in a vessel.
  • Kensey Kenneth (Hinsdale IL), Device for sealing percutaneous puncture in a vessel.
  • Lemelson Jerome H. (48 Parkside Dr. Princeton NJ 08540), Dispensing catheter and method.
  • Janese Woodrow W. (2806 N. Navarro ; Ste. M Victoria TX 79901), Dural sealing needle and method of use.
  • Devry William E. (Fairview Park OH), Fabric coating composition with low formaldehyde evolution.
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  • Makower Joshua (Nanuet NY) Vidal Claude A. (Santa Barbara CA) LeMott Steven R. (East Lyme CT) Wells Rodney E. (East Lyme CT) Banks Thomas F. (Santa Barbara CA), Hemostatic implant introducer.
  • Kensey Kenneth (Chester Springs PA) Nash John (Downingtown PA) Evans Douglas (King of Prussia PA), Hemostatic puncture closure system and method of use.
  • Kensey Kenneth (Chester Springs PA) Nash John E. (Downingtown PA) Evans Douglas (Devon PA), Hemostatic puncture closure system and method of use.
  • Mariotti Chris S. (Newington CT) Liu Ju-Chao (Newington CT), Hot strength cyanoacrylate adhesive composition.
  • Jones Lonnie S. (Minneapolis MN) Boespflug Donald W. (Lino Lakes MN) Ruhoff Philip J. (Minneapolis MN), Hydrolysis resistant alkyl resin coating composition.
  • Lemelson Jerome H. (85 Rector St. Metuchen NJ 08840), Injection catheter and method.
  • Fowler Bradford C. (Woodinville WA), Insertion assembly and method of inserting a vessel plug into the body of a patient.
  • Fowler Bradford C. (Woodinville WA), Insertion assembly and method of inserting a vessel plug into the body of a patient.
  • Fowler Bradford C. (Woodinville WA), Insertion assembly and method of inserting a vessel plug into the body of a patient.
  • Tiefenbrun Jonathan (62 Country Rd. Mamaronek NY 10543) Wilk Peter J. (185 W. End Ave. New York NY 10023), Instrument and associated method for applying biologically effective composition during laparoscopic operation.
  • Kusayama Senji (Toyonaka JPX) Nishi Eijiro (Otsu CA JPX) Stock Hugh J. (Saratoga CA), Locking and sealing compositions and methods for their application.
  • Kensey Kenneth (Hinsdale IL), Method and apparatus for sealing an opening in tissue of a living being.
  • Hermes Matthew E. (Easton CT) Muth Ross R. (Brookfield CT), Method for improving the storage stability of a polymeric article susceptible to hydrolytic degradation and resulting ar.
  • Hermes, Matthew E.; Kaplan, Donald S., Method for improving the storage stability of a polymeric braided suture susceptible to hydrolytic degradation and resulting article.
  • English James P. (Birmingham AL) McNeely Gerald W. (Spartanburg SC) Dunn Richard L. (Birmingham AL), Method for making a biodegradable adhesive for soft living tissue.
  • Chou Yungnien J. (Midland MI) Saam John C. (Midland MI), Method for preparing polyacetals and polyketals by emulsion polymerization.
  • Leung Jeffrey C. (Raleigh NC) Clark Jeffrey G. (Raleigh NC), Method of hemostatic sealing of blood vessels and internal organs.
  • Lee Benjamin I. (4911 Van Ness St ; NW. Washington DC 20016), Methods and device for percutanceous sealing of arterial puncture sites.
  • Shaffer John W. (Williamsport PA), Modified polycarbonate resin.
  • Kimura Kaoru (Kuroishi JPX) Sakabe Kazuyuki (Tokai JPX), Novel 2-cyanoacrylate, process for producing same and curable composition comprising same.
  • Kensey Kenneth (Chester Springs PA), Plug device for sealing openings and method of use.
  • Kensey Kenneth (Chester Springs PA) Nash John (Downingtown PA) Evans Douglas (King of Prussia PA), Plug device with pulley for sealing punctures in tissue and methods of use.
  • Sivaramakrishnan Parameswar (New Martinsville WV), Polycarbonate having improved hydrolytic stability.
  • Rosenfeld Jerold C. (Tonawanda NY), Polyester composition, process therefor and molded articles therefrom.
  • Sparer Randall V. (Lawrence KS) Zentner Gaylen (Lawrence KS), Process for the manufacture of bioerodible poly (orthoester)s and polyacetals.
  • Perry ; Ronald S., Process for the reduction of free formaldehyde on textile fabrics.
  • Stupka Jonathan C. (Austin) Bokros Jack C. (Austin) Emken Michael R. (Austin) Haubold Axel D. (Liberty Hill) Peters T. Scott (Georgetown TX), Prosthetic heart valve.
  • Woods John G. (Dublin IEX) Rooney John M. (Kildare IEX), Resists formed by vapor deposition of anionically polymerizable monomer.
  • Kronenthal Richard L. (Fair Lawn NJ) Schipper Edgar (Highland Park NJ), Surgical adhesives.
  • Weldon Thomas D. (Aguadilla PR) Larsen Charles (Aguadilla PR), Wound clotting device and method of using same.
  • Weldon Thomas D. (Aguadilla PRX) Larsen Charles (Aguadilla PRX), Wound treating device and method of using same.
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