초록 ▼

A topical insect repellent with extended duration of protection was obtained from mixtures of molecules based on two or more volatile repellent organic molecular species occurring naturally on the human skin surface. The novel repellent comprises mixtures of lower, intermediate, and higher volatilit

A topical insect repellent with extended duration of protection was obtained from mixtures of molecules based on two or more volatile repellent organic molecular species occurring naturally on the human skin surface. The novel repellent comprises mixtures of lower, intermediate, and higher volatility organic molecules. Active ingredients for formulations are obtained from homologous series of carboxylic acids, alcohols, ketones, and lactones which span a similar range of volatility and which occur naturally on the skin surface. Volatile silicone fluid imparts mildness and water repellency to the repellent formulations. The new natural repellent exhibits the longevity and repellency that is comparable to N,N-diethyl-m-toluamide (DEET), a synthetic compound employed in almost all commercial formulations, but the inventive natural repellent is more acceptable than DEET, which has an unpleasant odor and imparts a greasy feel to the skin. The inventive insect repellent, formulated in a volatile silicone fluid, was shown to repel and incapacitate stable flies. This finding demonstrated that repellency was not limited to mosquitoes, but extends to other biting flies or insects, thus demonstrating the utility of the novel insect repellent for protecting pets and livestock as well as humans.

대표청구항 ▼

[ What is claimed is:] [1.]1. A method for repelling flies away from a human or an animal, the method comprising:providing an insect repellant composition comprisinga) a dermatologically acceptable carrier, andb) active ingredients consisting of(i) octanoic acid,(ii) nonanoic acid, and(iii) decanoic

[ What is claimed is:] [1.]1. A method for repelling flies away from a human or an animal, the method comprising:providing an insect repellant composition comprisinga) a dermatologically acceptable carrier, andb) active ingredients consisting of(i) octanoic acid,(ii) nonanoic acid, and(iii) decanoic acid,wherein the active ingredients are in an amount effective to repel more flies away from a test subject that has been treated with the insect repellant composition than a control subject without the insect repellant composition after about 3 hours or more, andwherein the octanoic acid, the nonanoic acid, and the decanoic acid are in about a 1:1:1 ratio by weight in the active ingredients; andapplying a topical dose of the insect repellant composition to the human or the animal to repel flies, wherein the topical dose includes octanoic acid in an amount of about 0.2 mg/cm.sup.2 or more, nonanoic acid in an amount of about 0.2 mg/cm.sup.2 or more, and decanoic acid in an amount of about 0.2 mg/cm.sup.2 or more.