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Stabilized, acid-free formulation for sustained release of bupropion hydrochloride 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/20
  • A61K-009/22
  • A61K-009/28
  • A61K-009/14
  • A61K-047/00
출원번호 US-0562240 (2000-04-28)
발명자 / 주소
  • Chungi Shubha
  • Lin Kangwen
출원인 / 주소
  • Teva Pharmaceuticals USA, Inc.
대리인 / 주소
    Reed
인용정보 피인용 횟수 : 55  인용 특허 : 7

초록

Stabilized bupropion hydrochloride pharmaceutical compositions are disclosed that are free of acid additives and provide for a sustained release of the bupropion hydrochloride. The particulate bupropion hydrochloride may be coated with a membrane coating and large-size particles may also be used. Me

대표청구항

[ What is claimed is:] [1.]1. A pharmaceutical composition for oral administration, comprising a solid dosage form that is free of added acid and contains a therapeutically effective amount of particulate, crystalline bupropion hydrochloride as an active agent and a pharmaceutically acceptable carri

이 특허에 인용된 특허 (7)

  1. Ludwig Jennie Sue G. (Greenville NC) Bass ; Jr. William L. (Farmville NC) Sutton ; Jr. Joel E. (Greenville NC), Controlled sustained release tablets containing bupropion.
  2. Ruff Michael D. (Greenville NC) Kalidindi Sanyasi R. (Edison NJ) Sutton ; Jr. Joel E. (Greenville NC), Pharmaceutical composition containing bupropion hydrochloride and a stabilizer.
  3. Maitra Amitava ; Kulkarni Prakash Shriram ; Shah Bharat Bhogilal ; DeVito Joseph Michael, Pharmaceutical composition containing bupropion hydrochloride and an inorganic acid stabilizer.
  4. Wong Patrick S. L. ; Dong Liang-Chang ; Edgren David E. ; Theeuwes Felix ; Gardner Phyllis I. ; Jao Francisco ; Wan Jason J., Prolonged release active agent dosage form adapted for gastric retention.
  5. Ruff Michael D. (Greenville NC) Kalidindi Sanvasi R. (Edison NJ) Sutton ; Jr. Joel E. (Greenville NC), Stabilized Pharmaceutical.
  6. Ruff Michael D. ; Kalidindi Sanvasi R. ; Sutton ; Jr. Joel Elmore, Stabilized pharmaceutical.
  7. Ruff Michael David ; Kalidindi Sanyasi Raju ; Sutton ; Jr. Joel Elmore, Stabilized pharmaceutical composition containing bupropion.

이 특허를 인용한 특허 (55)

  1. Sanganabhatla, Shankar; Soni, Vijay; Khan, Mubeen Ahmed; Agarwal, Nandlal; Kamble, Hemanth; Gore, Sharad, Amorphous bupropion hydrobromide and preparation thereof.
  2. Rudnic,Edward M., Antibiotic composition with inhibitor.
  3. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  4. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  5. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  6. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  7. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  8. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  9. Burnside, Beth A.; Flanner, Henry H.; Rowlings, Colin, Antibiotic product, use and formulation thereof.
  10. Rudnic, Edward M.; Isbister, James D.; Treacy, Jr., Donald J.; Wassink, Sandra E., Antifungal once-a-day product, use and formulation thereof.
  11. Rudnic,Edward M.; Isbister,James D.; Treacy, Jr.,Donald J.; Wassink,Sandra E., Antiviral product, use and formulation thereof.
  12. Flanner, Henry H.; Guttendorf, Robert J.; Clausen, Susan P.; Treacy, Donald; Burnside, Beth A., Compositions and methods for improved efficacy of penicillin-type antibiotics.
  13. Cowley, Michael A.; McKinney, Anthony A.; Tollefson, Gary, Compositions and methods for increasing insulin sensitivity.
  14. Cowley, Michael A.; McKinney, Anthony A.; Tollefson, Gary, Compositions and methods for increasing insulin sensitivity.
  15. Klassen, Preston; Taylor, Kristin, Compositions and methods for reducing major adverse cardiovascular events.
  16. Klassen, Preston; Taylor, Kristin, Compositions and methods for weight loss in at risk patient populations.
  17. Klassen, Preston; Taylor, Kristin, Compositions and methods for weight loss in at risk patient populations.
  18. Klassen, Preston; Taylor, Kristin, Compositions and methods for weight loss in at risk patient populations.
  19. Klassen, Preston; Taylor, Kristin, Compositions and methods for weight loss in at risk patient populations.
  20. Weber, Eckard; Cowley, Michael Alexander, Compositions for affecting weight loss.
  21. Li, Boyong; Nangia, Avinash; Chen, Chih Ming; Cheng, Xiu Xiu, Controlled release oral dosage form.
  22. Li, Boyong; Nangia, Avinash; Chen, Chih Ming; Cheng, Xiu Xiu, Controlled release oral dosage form.
  23. Li, Boyong; Nangia, Avinash; Chen, Chih Ming; Cheng, Xiu Xiu, Controlled release oral dosage form.
  24. Li, Boyong; Nangia, Avinash; Chen, Chih Ming; Cheng, Xiu Xiu, Controlled release oral dosage form.
  25. Zerbe, Horst G.; Paiement, Nadine, Controlled-release pharmaceutical tablets.
  26. Lee, Hun Joo; Lim, Jung Youl; Jung, Yong Woo; Lim, Bum Hyun; Shim, Kwang Hyun; Choi, Jin Sung; Yang, Kwang Ho; Kim, Hyun Bin, Database cache system.
  27. Cherukuri, S. Rao, Drug delivery systems.
  28. McKinney, Anthony; Tollefson, Gary; Weber, Eckard; Soltero, Rick, Layered pharmaceutical formulations.
  29. McKinney, Anthony; Tollefson, Gary; Weber, Eckard; Soltero, Rick, Layered pharmaceutical formulations.
  30. Chow, San-Laung; Wong, David; Garcia, Damian, Methods and formulations for making pharmaceutical compositions containing bupropion.
  31. McKinney, Anthony A.; Tollefson, Gary; Weber, Eckard; Soltero, Rick, Methods for administering weight loss medications.
  32. McKinney, Anthony; Tollefson, Gary; Weber, Eckard; Soltero, Rick, Methods for administering weight loss medications.
  33. Dunayevich, Eduardo; Tollefson, Gary, Methods of providing weight loss therapy in patients with major depression.
  34. Klassen, Preston; Taylor, Kristin, Methods of treating overweight and obesity.
  35. Flanner, Henry H.; Tolle-Sander, Sanna; Treacy, Donald; Burnside, Beth A.; Clausen, Susan P., Modified release amoxicillin products.
  36. Oberegger, Werner; Maes, Paul; Jackson, Graham; Saleh, Mohammad Ashty, Modified release formulations of a bupropion salt.
  37. Oberegger, Werner; Maes, Paul; Jackson, Graham; Saleh, Mohammad Ashty, Modified release formulations of a bupropion salt.
  38. Oberegger, Werner; Zhou, Fang; Maes, Paul; Jackson, Graham; Saleh, Mohammad Ashty, Modified release formulations of a bupropion salt.
  39. Oberegger, Werner; Zhou, Fang; Maes, Paul; Turchetta, Stefano; Jackson, Graham; Massardo, Pietro; Saleh, Mohammad Ashty, Modified release formulations of a bupropion salt.
  40. Oberegger,Werner; Zhou,Fang; Maes,Paul; Turchetta,Stefano; Jackson,Graham; Massardo,Pietro; Saleh,Mohammad Ashty, Modified release formulations of a bupropion salt.
  41. Patel,Shashank Bababhai; Yadav,Kamala Sultansingh; Mandal,Jayant Kumar; Maheshwari,Kirti Bansidhar, Modified release oral dosage form using co-polymer of polyvinyl acetate.
  42. Oberegger, Werner; Eradiri, Okponanabofa; Zhou, Fang; Maes, Paul, Modified release tablet of bupropion hydrochloride.
  43. Oberegger, Werner; Zhou, Fang; Maes, Paul; Turchetta, Stefano; Jackson, Graham; Massardo, Pietro; Saleh, Mohammad Ashty, Modified-release formulations of a bupropion salt.
  44. Jeary,Theresa Ann; Morrissey,Catherine Ann; Stark,Paul, Multiparticulate controlled release selective serotonin reuptake inhibitor formulations.
  45. Rudnic, Edward M; Isbister, James D; Treacy, Jr., Donald J; Wassink, Sandra E, Once a day amoxicillin product comprising immediate and delayed release dosage forms.
  46. Flanner, Henry H.; Guttendorf, Robert; Treacy, Donald; Clausen, Susan P.; Burnside, Beth A., Pharmaceutical compositions and methods for improved bacterial eradication.
  47. Am Ende, Mary T.; Roy, Michael C.; Smith, Scott W.; Waterman, Kenneth C.; Moses, Sara Kristen, Pharmaceutical compositions of 5,7,14-triazatetracyclo[10.3.1.0.0]-hexadeca-2(11),3,5,7,9-pentaene.
  48. Cao, Bruce X.; Burnside, Beth A.; Wassink, Sandra E.; Baker, Matt R., Robust pellet.
  49. Zerbe, Horst; Paiement, Nadine; Angusti, Angela; Long, Cormac, Solid oral film dosage forms and methods for making same.
  50. Li, Boyong; Cheng, Xiu Xiu, Stable pharmaceutical compositions without a stabilizer.
  51. Li, Boyong; Cheng, Xiu Xiu, Stable pharmaceutical compositions without a stabilizer.
  52. McKinney, Anthony A.; Tollefson, Gary D.; Soltero, Richard; Dunzo, Thea Elise, Sustained release formulation of naltrexone.
  53. McKinney, Anthony A.; Tollefson, Gary D.; Soltero, Richard; Dunzo, Thea Elise, Sustained release formulation of naltrexone.
  54. Zerbe, Horst G.; Paiement, Nadine, Sustained-release bupropion and bupropion/mecamylamine tablets.
  55. Cao, Bruce; Wassink, Sandra E.; Treacy, Jr., Donald J.; Burnside, Beth A.; Rowlings, Colin E.; Bonck, John A., Tablet for pulsed delivery.
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